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Current Medical Research and Opinion Volume 20, 2004 - Issue 6
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Brief Report

Efficacy and tolerability of a new chlorhexidine-based vaginal gel in vaginal infections

Bruno Molteni Obstetric and Gynecology Department ‘Ospedale Civile’, Giussano, Italy
,
Antonietta D’Antuono Sexually Transmitted Diseases Center, Ospedale Sant’Orsola-Malpighi, Bologna, Italy
,
Patrizia Bandini Sexually Transmitted Diseases Center, Ospedale Sant’Orsola-Malpighi, Bologna, Italy
,
Giuseppe Sintini Obstetric and Gynecology Department, Ospedale Civile, Lugo, Italy
,
Eliana Barcellona Gynecology Service Vicenza, Italy
,
Antonella Agnello Gynecology Service Padua, Italy
&
Massimo Milani R&D Mipharm, Milan, ItalyCorrespondence[email protected]
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Pages 849-853 | Accepted 22 Mar 2004, Published online: 15 Apr 2004

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Hans Verstraelen & Rita Verhelst. (2009) Bacterial vaginosis: an update on diagnosis and treatment. Expert Review of Anti-infective Therapy 7:9, pages 1109-1124.
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Muhammad Ahsan Hafiz, Mohsin Ahmad Ghauri, Nasir Abbas, Talib Hussain & Nadeem Irfan Bukhari. (2023) Development of cervix-targeted hydrogel carrier for carboplatin-loaded nanosponges: In-vitro and ex-vivo evaluation. Journal of Drug Delivery Science and Technology 84, pages 104472.
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Mayram Hacioglu, Ozlem Oyardi, Fatima Nur Yilmaz & Markus Nagl. (2022) Comparative Fungicidal Activities of N-Chlorotaurine and Conventional Antiseptics against Candida spp. Isolated from Vulvovaginal Candidiasis. Journal of Fungi 8:7, pages 682.
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Željka Vanić, May Wenche Jøraholmen & Nataša Škalko-Basnet. (2021) Nanomedicines for the topical treatment of vulvovaginal infections: Addressing the challenges of antimicrobial resistance. Advanced Drug Delivery Reviews 178, pages 113855.
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Shahla Mirzaeei, Maryam Zangeneh, Firoozeh Veisi, Somayeh Parsa & Maryam Hematti. (2021) Chlorhexidine, clotrimazole, metronidazole and combination therapy in the treatment of vaginal infections. Journal of Medicine and Life 14:2, pages 250-256.
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Cathrin Alvendal, Soumitra Mohanty, Nina Bohm-Starke & Annelie Brauner. (2020) Anti-biofilm activity of chlorhexidine digluconate against Candida albicans vaginal isolates. PLOS ONE 15:9, pages e0238428.
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Mariana Tomás, Ana Palmeira-de-Oliveira, Sérgio Simões, José Martinez-de-Oliveira & Rita Palmeira-de-Oliveira. (2020) Bacterial vaginosis: Standard treatments and alternative strategies. International Journal of Pharmaceutics 587, pages 119659.
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Angelica Maria Parra Linares, Jairo Amaya-Guio, Carlos F Grillo-Ardila & Angelica Maria Toro Cubides. (2019) Antiseptics and disinfectants for the treatment of vaginal discharge in non-pregnant women. Cochrane Database of Systematic Reviews.
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Barbara Giordani, Angela Abruzzo, Umberto Maria Musazzi, Francesco Cilurzo, Fiore Pasquale Nicoletta, Francesco Dalena, Carola Parolin, Beatrice Vitali, Teresa Cerchiara, Barbara Luppi & Federica Bigucci. (2019) Freeze-Dried Matrices Based on Polyanion Polymers for Chlorhexidine Local Release in the Buccal and Vaginal Cavities. Journal of Pharmaceutical Sciences 108:7, pages 2447-2457.
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A. M. Savicheva, E. V. Spasibova & K. V. Shalepo. (2019) Investigation of the susceptibility of clinical microbial isolates from the female urogenital tract to the active ingredients contained in Depanthol. Rossiiskii vestnik akushera-ginekologa 19:1, pages 86.
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Daniela Machado, Joana Castro, Ana Palmeira-de-Oliveira, José Martinez-de-Oliveira & Nuno Cerca. (2016) Bacterial Vaginosis Biofilms: Challenges to Current Therapies and Emerging Solutions. Frontiers in Microbiology 6.
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Rita Palmeira-de-Oliveira, Ana Palmeira-de-Oliveira & José Martinez-de-Oliveira. (2015) New strategies for local treatment of vaginal infections. Advanced Drug Delivery Reviews 92, pages 105-122.
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Federica Bigucci, Angela Abruzzo, Beatrice Vitali, Bruno Saladini, Teresa Cerchiara, Maria Caterina Gallucci & Barbara Luppi. (2015) Vaginal inserts based on chitosan and carboxymethylcellulose complexes for local delivery of chlorhexidine: Preparation, characterization and antimicrobial activity. International Journal of Pharmaceutics 478:2, pages 456-463.
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Michele J. Anderson, Patrick J. Parks & Marnie L. Peterson. (2013) A mucosal model to study microbial biofilm development and anti-biofilm therapeutics. Journal of Microbiological Methods 92:2, pages 201-208.
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A. Abruzzo, F. Bigucci, T. Cerchiara, B. Saladini, M.C. Gallucci, F. Cruciani, B. Vitali & B. Luppi. (2013) Chitosan/alginate complexes for vaginal delivery of chlorhexidine digluconate. Carbohydrate Polymers 91:2, pages 651-658.
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Hans Verstraelen, Rita Verhelst, Kristien Roelens & Marleen Temmerman. (2012) Antiseptics and disinfectants for the treatment of bacterial vaginosis: A systematic review. BMC Infectious Diseases 12:1.
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Craig R. Cohen, Su-Chun Cheng, Stephen Shiboski, Tsungai Chipato, Martin Matu, James Mwangi, Monalisa E. S. Mutimutema, Jennifer Tuveson, Mavis Kamba, Nancy Padian & Ariane van der Straten. (2012) Diaphragm Used with Replens Gel and Risk of Bacterial Vaginosis: Results from a Randomized Controlled Trial. Infectious Diseases in Obstetrics and Gynecology 2012, pages 1-8.
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José das Neves, Eugénia Pinto, Branca Teixeira, Gustavo Dias, Patrocínia Rocha, Teresa Cunha, Bárbara Santos, Maria H Amaral & Maria F Bahia. (2008) Local Treatment of Vulvovaginal Candidosis. Drugs 68:13, pages 1787-1802.
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