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Review

A review of the metabolic effects of sibutramine

, , , &
Pages 457-466 | Accepted 08 Feb 2005, Published online: 01 Mar 2005

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Andréa Name Colado Simão, Marcell Alysson Batisti Lozovoy & Isaias Dichi. (2012) The uric acid metabolism pathway as a therapeutic target in hyperuricemia related to metabolic syndrome. Expert Opinion on Therapeutic Targets 16:12, pages 1175-1187.
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Niki Katsiki, Dimitri P Mikhailidis, Anna Gotzamani-Psarrakou, John G Yovos & Dimitrios Karamitsos. (2011) Effect of various treatments on leptin, adiponectin, ghrelin and neuropeptide Y in patients with type 2 diabetes mellitus. Expert Opinion on Therapeutic Targets 15:4, pages 401-420.
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Konstantinos Tziomalos, Gerasimos E Krassas & Themistoklis Tzotzas. (2009) The use of sibutramine in the management of obesity and related disorders: An update. Vascular Health and Risk Management 5, pages 441-452.
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M Florentin, EN Liberopoulos, TD Filippatos, C Kostara, A Tselepis, DP Mikhailidis & M Elisaf. (2008) Effect of rimonabant, micronised fenofibrate and their combination on cardiometabolic risk factors in overweight/obese patients: a pilot study. Expert Opinion on Pharmacotherapy 9:16, pages 2741-2750.
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E Nakou, TD Filippatos, EN Liberopoulos, AD Tselepis, DN Kiortsis, DP Mikhailidis & MS Elisaf. (2008) Effects of sibutramine plus verapamil sustained release/trandolapril combination on blood pressure and metabolic variables in obese hypertensive patients. Expert Opinion on Pharmacotherapy 9:10, pages 1629-1639.
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E. S. Nakou, T. D. Filippatos, M. Georgoula, D. N. Kiortsis, A. D. Tselepis, D. P. Mikhailidis & M. S. Elisaf. (2008) The effect of orlistat and ezetimibe, alone or in combination, on serum LDL and small dense LDL cholesterol levels in overweight and obese patients with hypercholesterolaemia. Current Medical Research and Opinion 24:7, pages 1919-1929.
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Alessandro Federico, Marco Niosi, Camillo Del Vecchio Blanco & Carmela Loguercio. (2008) Emerging drugs for non-alcoholic fatty liver disease. Expert Opinion on Emerging Drugs 13:1, pages 145-158.
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Harold Bays, Lawrence Blonde & Robert Rosenson. (2006) Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients?. Expert Review of Cardiovascular Therapy 4:6, pages 871-895.
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T. D. Filippatos, D. N. Kiortsis, E. N. Liberopoulos, M. Georgoula, D. P. Mikhailidis & M. S. Elisaf. (2005) Effect of orlistat, micronised fenofibrate and their combination on metabolic parameters in overweight and obese patients with the metabolic syndrome: the FenOrli study. Current Medical Research and Opinion 21:12, pages 1997-2006.
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Sheila A Doggrell. (2005) Is the cannabinoid CB1 receptor antagonist rimonabant advancing the treatment of obesity?. Expert Opinion on Pharmacotherapy 6:12, pages 2141-2144.
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Titus Kaletta & Michael O. Hengartner. (2006) Finding function in novel targets: C. elegans as a model organism. Nature Reviews Drug Discovery 5:5, pages 387-399.
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AH Barnett & S Bellary. (2006) Novel metabolic drugs for the management of type 2 diabetes. Practical Diabetes International 23:3, pages 129-134.
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Harold Bays & Carlos A. Dujovne. (2006) Adiposopathy is a more rational treatment target for metabolic disease than obesity alone. Current Atherosclerosis Reports 8:2, pages 144-156.
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Jan O. Nehlin. 2006. Prevention and Treatment of Age-related Diseases. Prevention and Treatment of Age-related Diseases 133 157 .
E. N. Liberopoulos, D. P. Mikhailidis & M. S. Elisaf. (2005) Diagnosis and management of the metabolic syndrome in obesity. Obesity Reviews 6:4, pages 283-296.
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R. L. Kennedy & E. Y. H. Khoo. (2005) New options for drug treatment of obesity in patients with Type 2 diabetes. Diabetic Medicine 22:s4, pages 23-26.
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