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Current Medical Research and Opinion Volume 21, 2005 - Issue 5
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Original Article

Imipenem/cilastatin versus piperacillin/tazobactam plus amikacin for empirical therapy in febrile neutropenic patients: results of the COSTINE study

Miguel A. Sanz Servicio de Hematología, Hospital Universitario La Fe, Valencia, Spain
,
Arancha Bermúdez Servicio de Hematología, Hospital Universitario Marqués de Valdecilla, Santander, Spain
,
Montserrat Rovira Servicio de Hematología, Hospital Clínic i Provincial, Barcelona, Spain
,
Juan Besalduch Servicio de Hematología, Hospital Son Dureta, Palma de Mallorca, Spain
,
Maria-Jesus Pascual Servicio de Hematología, Hospital Carlos Haya, Málaga, Spain
,
Gonzalo Nocea Department of Outcomes Research, Merck Sharp & Dohme of Spain, Madrid, Spain
,
César Sanz-Rodríguez Department of Clinical Research, Merck Sharp & Dohme of Spain, Madrid, SpainCorrespondence[email protected]
& for the COSTINE StudyGroup show all
Pages 645-655 | Accepted 17 Mar 2005, Published online: 31 Mar 2005

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Alfred Gin, Leanne Dilay, James A Karlowsky, Andrew Walkty, Ethan Rubinstein & George G Zhanel. (2007) Piperacillin–tazobactam: a β-lactam/β-lactamase inhibitor combination. Expert Review of Anti-infective Therapy 5:3, pages 365-383.
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Articles from other publishers (12)

Charulata Ramaprasad & Kenneth J. Pursell. 2014. Infectious Complications in Cancer Patients. Infectious Complications in Cancer Patients 351 370 .
Mical Paul, Yaakov Dickstein, Agata Schlesinger, Simona Grozinsky-Glasberg, Karla Soares-Weiser & Leonard Leibovici. (2013) Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia. Cochrane Database of Systematic Reviews 2016:9.
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Jong Kim, Joowon Chung, Sang-Ho Choi, Hang Jang, Sang-Bum Hong, Chae-Man Lim & Younsuck Koh. (2012) Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial. Critical Care 16:1, pages R28.
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N. Oztoprak, N. Piskin, H. Aydemir, G. Celebi, D. Akduman, A. S. Keskin, A. Gokmen, H. Engin & H. Ankarali. (2010) Piperacillin-tazobactam Versus Carbapenem Therapy With and Without Amikacin as Empirical Treatment of Febrile Neutropenia in Cancer Patients: Results of an Open Randomized Trial at a University Hospital. Japanese Journal of Clinical Oncology 40:8, pages 761-767.
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Fernando Antonanzas, Roberto Rodríguez‐Ibeas, Carmelo Juárez, Florencia Hutter, Reyes Lorente & Mariola Pinillos. (2009) Transferability indices for health economic evaluations: methods and applications. Health Economics 18:6, pages 629-643.
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Cornelia B. Landersdorfer, Carl M. J. Kirkpatrick, Martina Kinzig, Jürgen B. Bulitta, Ulrike Holzgrabe & Fritz Sörgel. (2008) Inhibition of flucloxacillin tubular renal secretion by piperacillin. British Journal of Clinical Pharmacology 66:5, pages 648-659.
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Tore Midtvedt. 2008. A worldwide yearly survey of new data and trends in adverse drug reactions and interactions. A worldwide yearly survey of new data and trends in adverse drug reactions and interactions 280 296 .
Lubos Drgona, Mical Paul, Giampaolo Bucaneve, Thierry Calandra & Francesco Menichetti. (2007) The need for aminoglycosides in combination with β-lactams for high-risk, febrile neutropaenic patients with leukaemia. European Journal of Cancer Supplements 5:2, pages 13-22.
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E. J. Bow, C. Rotstein, G. A. Noskin, M. L. re, A. P. Schwarer, B. H. Segal, J. F. Seymour, J. Szer & S. Sanche. (2006) A Randomized, Open-Label, Multicenter Comparative Study of the Efficacy and Safety of Piperacillin-Tazobactam and Cefepime for the Empirical Treatment of Febrile Neutropenic Episodes in Patients with Hematologic Malignancies. Clinical Infectious Diseases 43:4, pages 447-459.
Crossref
Isidro Jarque, Miguel Salavert & Miguel A. Sanz. (2005) Manejo del paciente neutropénico con fiebre. Enfermedades Infecciosas y Microbiología Clínica 23, pages 24-29.
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Enric Carreras & Josep Mensa. (2005) Neutropenia febril: pasado, presente y futuro. Enfermedades Infecciosas y Microbiolog?a Cl?nica 23, pages 2-6.
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Mical Paul, Agata Schlesinger, Simona Grozinsky-Glasberg, Karla Soares-Weiser & Leonard Leibovici. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.

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