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Original Article

The effects of teriparatide on the incidence of back pain in postmenopausal women with osteoporosis

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Pages 1027-1034 | Accepted 29 Apr 2005, Published online: 31 May 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Sophia Ish-Shalom, Constantin Dumitrache, Timour Fikry El-Husseini, Azza Hussein, Clare Barker & Imre Pavo. (2011) Postmenopausal women with osteoporosis: experience when treated with teriparatide in clinical practice. Current Medical Research and Opinion 27:2, pages 343-353.
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George Lyritis, Fernando Marin, Clare Barker, Michael Pfeifer, Jordi Farrerons, Kim Brixen, Javier del Pino, Richard Keen & Thomas N. Nickelsen. (2010) Back pain during different sequential treatment regimens of teriparatide: results from EUROFORS. Current Medical Research and Opinion 26:8, pages 1799-1807.
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S. Scharla, H. Oertel, K. Helsberg, F. Kessler, F. Langer & T. Nickelsen. (2006) Skeletal pain in postmenopausal women with osteoporosis: prevalence and course during raloxifene treatment in a prospective observational study of 6 months duration. Current Medical Research and Opinion 22:12, pages 2393-2402.
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Articles from other publishers (42)

Marie‐Eva Pickering, Rose‐Marie Javier, Sandrine Malochet, Gisele Pickering & Jules Desmeules. (2023) Osteoporosis treatment and pain relief: A scoping review. European Journal of Pain 28:1, pages 3-20.
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Pun Yuet Lam, Prudence Wing Hang Cheung, Sin Ting Lau & Jason Pui Yin Cheung. (2022) Quality of life of postmenopausal women with teriparatide, denosumab and alendronate: One-year prospective study with a propensity score-matched comparison. Journal of Orthopaedics, Trauma and Rehabilitation 30:1.
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Masayuki Miyagi, Gen Inoue, Kosuke Murata, Tomohisa Koyama, Akiyoshi Kuroda, Ayumu Kawakubo, Yuji Yokozeki, Yusuke Mimura, Yuta Nanri, Kazuhide Inage, Tsutomu Akazawa, Seiji Ohtori, Kentaro Uchida & Masashi Takaso. (2021) Factors associated with pain-related disorders and gait disturbance scores from the Japanese orthopedic association back pain evaluation questionnaire and Oswestry Disability Index in patients with osteoporosis. Archives of Osteoporosis 17:1.
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John H Krege, Alicia W Gilsenan, John L Komacko & Nicole Kellier‐Steele. (2022) Teriparatide and Osteosarcoma Risk: History, Science, Elimination of Boxed Warning, and Other Label Updates. JBMR Plus 6:9.
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Nimesh Patel, Mohamed Fayed, Priyansh Faldu, Wissam Maroun & Janki Chandarana. (2022) Chronic Proton-Pump Inhibitor Therapy and Fracture Risk in Women Aged Between 50 and 65 years: A Retrospective Case-Control Study. Cureus.
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N. O. Khovasova, E. N. Dudinskaya, A. V. Naumov, O. N. Tkacheva, L. V. Machekhina & Ju. S. Onuchina. (2022) Effect of bone anabolic therapy on bone remodeling and bone density in geriatric patients with osteoporosis and falling syndrome. Problems of Endocrinology 68:3, pages 67-75.
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Fernando Marin & Yanfei L. Ma. 2022. Osteoporotic Fracture and Systemic Skeletal Disorders. Osteoporotic Fracture and Systemic Skeletal Disorders 339 359 .
Takahiro Mori, Carolyn J. Crandall, Tomoko Fujii & David A. Ganz. (2021) Cost-effectiveness of sequential daily teriparatide/weekly alendronate compared with alendronate monotherapy for older osteoporotic women with prior vertebral fracture in Japan. Archives of Osteoporosis 16:1.
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Takashi Hara, Yasukazu Hijikata, Yukiko Matsubara & Norio Watanabe. (2021) Pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic kidney disease stages 3-5D. Cochrane Database of Systematic Reviews 2021:7.
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海铭 李. (2021) Effects of Teriparatide (PTH 1-34) and Zoledronic Acid on Postmenopausal Osteoporotic Patients with Low Bone Turnover. Advances in Clinical Medicine 11:06, pages 2670-2677.
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Cristina Carbonell Abella & Daniel Martínez Laguna. (2020) Fractura aplastamiento vertebral por fragilidad. FMC - Formación Médica Continuada en Atención Primaria 27:7, pages 320-328.
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Tomoya Tanaka, Ryoko Takao-Kawabata, Aya Takakura, Yukari Shimazu, Momoko Nakatsugawa, Akitoshi Ito, Ji-Won Lee, Koh Kawasaki & Tadahiro Iimura. (2020) Teriparatide relieves ovariectomy-induced hyperalgesia in rats, suggesting the involvement of functional regulation in primary sensory neurons by PTH-mediated signaling. Scientific Reports 10:1.
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Sho Kato, Hiroki Wakabayashi, Taro Nakagawa, Gaku Miyamura, Yohei Naito, Takahiro Iino & Akihiro Sudo. (2019) Teriparatide improves pain-related behavior and prevents bone loss in ovariectomized mice. Journal of Orthopaedic Surgery 28:1, pages 230949901989319.
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Fumitoshi Omura. (2019) Impact of patient background factors on the treatment efficacy of once-weekly teriparatide. Osteoporosis and Sarcopenia 5:2, pages 51-56.
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Bente L. Langdahl, Stuart Silverman, Saeko Fujiwara, Ken Saag, Nicola Napoli, Satoshi Soen, Hiroyuki Enomoto, Thomas E. Melby, Damon P. Disch, Fernando Marin & John H. Krege. (2018) Real-world effectiveness of teriparatide on fracture reduction in patients with osteoporosis and comorbidities or risk factors for fractures: Integrated analysis of 4 prospective observational studies. Bone 116, pages 58-66.
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Nicola Napoli, Bente. L. Langdahl, Östen Ljunggren, Eric Lespessailles, George Kapetanos, Tomaz Kocjan, Tatjana Nikolic, Pia Eiken, Helmut Petto, Thomas Moll, Erik Lindh & Fernando Marin. (2018) Effects of Teriparatide in Patients with Osteoporosis in Clinical Practice: 42-Month Results During and After Discontinuation of Treatment from the European Extended Forsteo® Observational Study (ExFOS). Calcified Tissue International 103:4, pages 359-371.
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. (2018) Manage osteoporotic pain by treating osteoporosis and taking a multidimensional approach to pain management. Drugs & Therapy Perspectives 34:7, pages 311-315.
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R. Vellucci, R. Terenzi, J. A Kanis, H. G. Kress, R. D. Mediati, J.-Y. Reginster, R. Rizzoli & M. L. Brandi. (2018) Understanding osteoporotic pain and its pharmacological treatment. Osteoporosis International 29:7, pages 1477-1491.
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Antonino Catalano, Gabriella Martino, Nunziata Morabito, Claudia Scarcella, Agostino Gaudio, Giorgio Basile & Antonino Lasco. (2017) Pain in Osteoporosis: From Pathophysiology to Therapeutic Approach. Drugs & Aging 34:10, pages 755-765.
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Ivo K. GenevMatthew K. TobinSaher P. Zaidi, Sajeel R. Khan, Farid M. L. Amirouche & Ankit I. Mehta. (2017) Spinal Compression Fracture Management. Global Spine Journal 7:1, pages 71-82.
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Bente L. Langdahl, Östen Ljunggren, Claude-Laurent Benhamou, Fernando Marin, George Kapetanos, Tomaz Kocjan, Eric Lespessailles, Nicola Napoli, Tatjana Nikolic, Helmut Petto, Thomas Moll & Erik Lindh. (2016) Fracture Rate, Quality of Life and Back Pain in Patients with Osteoporosis Treated with Teriparatide: 24-Month Results from the Extended Forsteo Observational Study (ExFOS). Calcified Tissue International 99:3, pages 259-271.
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Fergus E. McKiernan. (2016) Violet Fox: A Clinical View of Vertebral Fractures. Journal of Clinical Densitometry 19:1, pages 35-39.
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Kyoung Min Lee, Chin Youb Chung, Soon-Sun Kwon, Tae Gyun Kim, In Hyeok Lee, Ki Jin Jung, Jin Woo Park, Sang Young Moon & Moon Seok Park. (2014) Bone mineral density is not associated with musculoskeletal pain in postmenopausal Korean women aged ≥50 years. Clinical Rheumatology 34:2, pages 337-343.
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O. Lamy, B. Uebelhart & B. Aubry-Rozier. (2013) Risks and benefits of percutaneous vertebroplasty or kyphoplasty in the management of osteoporotic vertebral fractures. Osteoporosis International 25:3, pages 807-819.
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Östen Ljunggren, Annabel Barrett, Ivaylo Stoykov, Bente L Langdahl, Willem F Lems, J Bernard Walsh, Astrid Fahrleitner-Pammer, Gerald Rajzbaum, Franz Jakob, Dimitrios Karras & Fernando Marin. (2013) Effective osteoporosis treatment with teriparatide is associated with enhanced quality of life in postmenopausal women with osteoporosis: the European Forsteo Observational Study. BMC Musculoskeletal Disorders 14:1.
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Daniel R. Murphy, Robert W. Klein, Lee J. Smolen, Timothy M. Klein & Stephen D. Roberts. (2013) Using Common Random Numbers in Health Care Cost-Effectiveness Simulation Modeling. Health Services Research 48:4, pages 1508-1525.
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Daniel R Murphy, Lee J Smolen, Timothy M Klein & Robert W Klein. (2012) The cost effectiveness of teriparatide as a first-line treatment for glucocorticoid-induced and postmenopausal osteoporosis patients in Sweden. BMC Musculoskeletal Disorders 13:1.
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P. Hadji, J. R. Zanchetta, L. Russo, C. P. Recknor, K. G. Saag, F. E. McKiernan, S. L. Silverman, J. Alam, R. T. Burge, J. H. Krege, M. C. Lakshmanan, D. N. Masica, B. H. Mitlak & J. L. Stock. (2011) The effect of teriparatide compared with risedronate on reduction of back pain in postmenopausal women with osteoporotic vertebral fractures. Osteoporosis International 23:8, pages 2141-2150.
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Y.-Y. Tseng, C.-H. Su, T.-N. Lui, Y.-S. Yeh & S.-H. Yeh. (2011) Prospective comparison of the therapeutic effect of teriparatide with that of combined vertebroplasty with antiresorptive agents for the treatment of new-onset adjacent vertebral compression fracture after percutaneous vertebroplasty. Osteoporosis International 23:5, pages 1613-1622.
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Po-Hsun Tu, Zhuo-Hao Liu, Shih-Tseng Lee & Jyi-Feng Chen. (2012) Treatment of repeated and multiple new-onset osteoporotic vertebral compression fractures with teriparatide. Journal of Clinical Neuroscience 19:4, pages 532-535.
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Jane A Cauley, Dennis Black, Steven Boonen, Steven R Cummings, Peter Mesenbrink, Lisa Palermo, Zulema Man, Peyman Hadji & Ian R Reid. (2011) Once-yearly zoledronic acid and days of disability, bed rest, and back pain: Randomized, controlled HORIZON Pivotal Fracture Trial. Journal of Bone and Mineral Research 26:5, pages 984-992.
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Bente L. Langdahl, Gerald Rajzbaum, Franz Jakob, Dimitrios Karras, Östen Ljunggren, Willem F. Lems, Astrid Fahrleitner-Pammer, J. Bernard Walsh, Clare Barker, Alexey Kutahov & Fernando Marin. (2009) Reduction in Fracture Rate and Back Pain and Increased Quality of Life in Postmenopausal Women Treated with Teriparatide: 18-Month Data from the European Forsteo Observational Study (EFOS). Calcified Tissue International 85:6, pages 484-493.
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R. Lindsay, P. Miller, G. Pohl, E. V. Glass, P. Chen & J. H. Krege. (2008) Relationship between duration of teriparatide therapy and clinical outcomes in postmenopausal women with osteoporosis. Osteoporosis International 20:6, pages 943-948.
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Fergus Eoin McKiernan. (2009) The broadening spectrum of osteoporotic vertebral fracture. Skeletal Radiology 38:4, pages 303-308.
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R. M. Francis, T. J. Aspray, G. Hide, A. M. Sutcliffe & P. Wilkinson. (2007) Back pain in osteoporotic vertebral fractures. Osteoporosis International 19:7, pages 895-903.
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Paul D. Miller. (2008) Safety of parathyroid hormone for the treatment of osteoporosis. Current Osteoporosis Reports 6:1, pages 12-16.
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Stephanie K A Blick, Sohita Dhillon & Susan J Keam. (2008) Teriparatide. Drugs 68:18, pages 2709-2737.
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S. Manuele, L. Sorbello, N. Puglisi, S. Grasso, L. La Malfa, G. D’Urbino, M. Rizzotto, S. Strano & D. Maugeri. (2007) The teriparatide in the treatment of severe senile osteoporosis. Archives of Gerontology and Geriatrics 44, pages 249-258.
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P. Vestergaard, N. R. Jorgensen, L. Mosekilde & P. Schwarz. (2006) Effects of parathyroid hormone alone or in combination with antiresorptive therapy on bone mineral density and fracture risk – a meta-analysis. Osteoporosis International 18:1, pages 45-57.
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M. C. Nevitt, P. Chen, D. P. Kiel, J.-Y. Reginster, R. K. Dore, J. R. Zanchetta, E. V. Glass & J. H. Krege. (2006) Reduction in the risk of developing back pain persists at least 30 months after discontinuation of teriparatide treatment: a meta-analysis. Osteoporosis International 17:11, pages 1630-1637.
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Françoise Debiais & Géraldine Durand. (2006) Le tériparatide. Revue du Rhumatisme 73:8, pages 838-845.
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Michael C. Nevitt, Peiqi Chen, Robin K. Dore, Jean-Yves Reginster, Douglas P. Kiel, Jose R. Zanchetta, Emmett V. Glass & John H. Krege. (2005) Reduced risk of back pain following teriparatide treatment: a meta-analysis. Osteoporosis International 17:2, pages 273-280.
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