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Original Article

Real-world utilization of DMARDs and biologics in rheumatoid arthritis: the RADIUS (Rheumatoid Arthritis Disease-Modifying Anti-Rheumatic Drug Intervention and Utilization Study) study

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Pages 169-183 | Accepted 07 Nov 2005, Published online: 05 Dec 2005

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Read on this site (6)

Katsuhiko Takabayashi, Fumihiko Ando & Takahiro Suzuki. (2019) Comparing the effectiveness of biological disease-modifying antirheumatic drugs using real-world data. Modern Rheumatology 29:1, pages 87-97.
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Takao Koike, Masayoshi Harigai, Shigeko Inokuma, Naoki Ishiguro, Junnosuke Ryu, Tsutomu Takeuchi, Yoshiya Tanaka, Hisashi Yamanaka, Koichi Fujii, Takunari Yoshinaga, Bruce Freundlich & Michio Suzukawa. (2011) Postmarketing surveillance of safety and effectiveness of etanercept in Japanese patients with rheumatoid arthritis. Modern Rheumatology 21:4, pages 343-351.
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Juan Li, EricM. Chi, Chunyao Feng & Shein-Chung Chow. (2011) Imputation Method Adjusted for Covariates for Nonrespondents in Instruments with Applications. Journal of Biopharmaceutical Statistics 21:2, pages 342-354.
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Wayne N Burton, Alan Morrison, Yong Yuan, Tracy Li, Riccardo E Marioni & Ross Maclean. (2008) Productivity cost model of the treatment of rheumatoid arthritis with abatacept. Journal of Medical Economics 11:1, pages 3-21.
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Chenglong Han, Ning Zhao, Abizer Gaslightwala & Mohan Bala. (2007) An epidemiological and healthcare utilisation study of rheumatoid arthritis in an adult population in the US. Journal of Medical Economics 10:4, pages 489-499.
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Arthur L. Weaver, Richard L. Lautzenheiser, Michael H. Schiff, Allan Gibofsky, James L. Perruquet, John Luetkemeyer, Harold E. Paulus, H. Amy Xia & Jonathan A. Leff. (2006) Real-world effectiveness of select biologic and DMARD monotherapy and combination therapy in the treatment of rheumatoid arthritis: results from the RADIUS observational registry. Current Medical Research and Opinion 22:1, pages 185-198.
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Chi Zhang, Daogang Guan, Miao Jiang, Chao Liang, Li Li, Ning Zhao, Qinglin Zha, Wandong Zhang, Cheng Lu, Ge Zhang, Jian Liu & Aiping Lu. (2019) Efficacy of leflunomide combined with ligustrazine in the treatment of rheumatoid arthritis: prediction with network pharmacology and validation in a clinical trial. Chinese Medicine 14:1.
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Sara Monti, Vittorio Grosso, Monica Todoerti & Roberto Caporali. (2018) Randomized controlled trials and real-world data: differences and similarities to untangle literature data. Rheumatology 57:Supplement_7, pages vii54-vii58.
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Priyanka Vashisht, Harlan Sayles, Amy C. Cannella, Ted R. Mikuls & Kaleb Michaud. (2016) Generalizability of Patients With Rheumatoid Arthritis in Biologic Agent Clinical Trials. Arthritis Care & Research 68:10, pages 1478-1488.
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Abdul Samad, Abdul Khalil, Iftikhar Ali & Aziz Ullah Khan. (2016) Methotrexate‐induced pneumonitis in a patient with rheumatoid arthritis: a case report. Journal of Pharmacy Practice and Research 46:3, pages 256-260.
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Matthew Geisz, Christina Ha, Michael D. Kappelman, Christopher F. Martin, Wenli Chen, Kristen Anton, Robert S. Sandler & Millie D. Long. (2016) Medication Utilization and the Impact of Continued Corticosteroid Use on Patient-reported Outcomes in Older Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases 22:6, pages 1435-1441.
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John Koo, Ethan Levin, Argentina Leon, Jashin Wu & Alice GottliebJason Emer & Mark Lebwohl. 2014. Moderate to Severe Psoriasis, Fourth Edition. Moderate to Severe Psoriasis, Fourth Edition 121 138 .
Joseph A. Markenson, Andrew S. Koenig, Jing Yuan Feng, Sandeep Chaudhari, Debra J. Zack, David Collier & Arthur Weaver. (2013) Comparison of Physician and Patient Global Assessments Over Time in Patients With Rheumatoid Arthritis. Journal of Clinical Rheumatology 19:6, pages 317-323.
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Arthur Weaver, Orrin Troum, Michele Hooper, Andrew S. Koenig, Sandeep Chaudhari, JingYuan Feng & Deborah Wenkert. (2013) Rheumatoid Arthritis Disease Activity and Disability Affect the Risk of Serious Infection Events in RADIUS 1. The Journal of Rheumatology 40:8, pages 1275-1281.
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Federico Augustovski, Andrea Beratarrechea, Vilma Irazola, Fernando Rubinstein, Pablo Tesolin, Juan Gonzalez, Verónica Lencina, Marina Scolnik, Christian Waimann, David Navarta, Gustavo Citera & Enrique R. Soriano. (2013) Patient Preferences for Biologic Agents in Rheumatoid Arthritis: A Discrete-Choice Experiment. Value in Health 16:2, pages 385-393.
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J. Zeidler, H. Zeidler & J.-M. Graf von der Schulenburg. (2012) Therapie der rheumatoiden Arthritis mit MethotrexatTherapy of rheumatoid arthritis with methotrexate. Zeitschrift für Rheumatologie 71:10, pages 900-907.
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Arun Shrivastava & Dhanita Khanna. (2012) CHOPping the biologics?!. Indian Journal of Rheumatology 7:1, pages 29-34.
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Daniel H. Solomon, John Z. Ayanian, Ed Yelin, Tamara Shaykevich, M. Alan Brookhart & Jeffrey N. Katz. (2012) Use of disease‐modifying medications for rheumatoid arthritis by race and ethnicity in the National Ambulatory Medical Care Survey. Arthritis Care & Research 64:2, pages 184-189.
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John J. Cush. 2012. Great Health Care. Great Health Care 123 136 .
Sarika Ogale, Elena Hitraya & Henry J Henk. (2011) Patterns of biologic agent utilization among patients with rheumatoid arthritis: a retrospective cohort study. BMC Musculoskeletal Disorders 12:1.
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Alexandra N Colebatch, Jonathan L Marks & Christopher J Edwards. (2011) Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis). Cochrane Database of Systematic Reviews.
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JOSEPH A. MARKENSON, ALLAN GIBOFSKY, WILLIAM R. PALMER, EDWARD C. KEYSTONE, MICHAEL H. SCHIFF, JINGYUAN FENG & SCOTT W. BAUMGARTNER. (2011) Persistence with Anti-Tumor Necrosis Factor Therapies in Patients with Rheumatoid Arthritis: Observations from the RADIUS Registry. The Journal of Rheumatology 38:7, pages 1273-1281.
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Michael A. Lane, Jay R. McDonald, Angelique L. Zeringue, Liron Caplan, Jeffrey R. Curtis, Prabha Ranganathan & Seth A. Eisen. (2011) TNF-α Antagonist Use and Risk of Hospitalization for Infection in a National Cohort of Veterans With Rheumatoid Arthritis. Medicine 90:2, pages 139-145.
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Ronald F. van Vollenhoven & Johan L. Severens. (2010) Observational studies: a valuable source for data on the true value of RA therapies. Clinical Rheumatology 30:S1, pages 19-24.
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ALLAN GIBOFSKY, WILLIAM R. PALMER, EDWARD C. KEYSTONE, MICHAEL H. SCHIFF, JINGYUAN FENG, PETER McCROSKERY, SCOTT W. BAUMGARTNER & JOSEPH A. MARKENSON. (2011) Rheumatoid Arthritis Disease-modifying Antirheumatic Drug Intervention and Utilization Study: Safety and Etanercept Utilization Analyses from the RADIUS 1 and RADIUS 2 Registries. The Journal of Rheumatology 38:1, pages 21-28.
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Jean-Marie Berthelot, Stéphanie Benoist-Gérard, Benoît le Goff, Florence Muller-Chevalet & Yves Maugars. (2010) Outcome and safety of TNFα antagonist therapy in 475 consecutive outpatients (with rheumatoid arthritis or spondyloarthropathies) treated by a single physician according to their eligibility for clinical trials. Joint Bone Spine 77:6, pages 564-569.
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Milka Maravic. (2010) Impact économique des biothérapies dans le traitement de la polyarthrite rhumatoïde (PR) en France. Revue du Rhumatisme 77:5, pages 474-479.
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P Taylor, B Manger, J Alvaro-Gracia, R Johnstone, J Gomez-Reino, E Eberhardt, F Wolfe, S Schwartzman, N Furfaro & A Kavanaugh. (2010) Patient Perceptions concerning Pain Management in the Treatment of Rheumatoid Arthritis. Journal of International Medical Research 38:4, pages 1213-1224.
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Jean-Marie Berthelot, Stéphanie Benoist-Gérard, Benoît le Goff, Florence Muller-Chevalet & Yves Maugars. (2010) Réponse et tolérance aux anti-TNF des 475 premiers patients (polyarthrites rhumatoïdes ou spondylarthrites) traités par un même praticien, selon la capacité de ceux-ci à participer ou non aux études pivots. Revue du Rhumatisme 77:4, pages 344-349.
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Milka Maravic. (2010) Economic impact of rheumatoid arthritis (RA) biotherapies in France. Joint Bone Spine 77:4, pages 319-324.
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Leona Cuttler, Detelina Marinova, Mary Beth Mercer, Alfred Connors, Rebecca Meehan & J B. Silvers. (2009) Patient, Physician, and Consumer Drivers. Medical Care 47:8, pages 858-865.
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Charles J. Malemud. (2009) The Discovery of Novel Experimental Therapies for Inflammatory Arthritis. Mediators of Inflammation 2009, pages 1-16.
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Jason Emer. 2008. Moderate-to-Severe Psoriasis, Third Edition. Moderate-to-Severe Psoriasis, Third Edition 193 217 .
B. Chikura, N. Sathi, S. Lane & J. K. Dawson. (2008) Variation of immunological response in methotrexate-induced pneumonitis. Rheumatology 47:11, pages 1647-1650.
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Kenneth G. Saag, Gim Gee Teng, Nivedita M. Patkar, Jeremy Anuntiyo, Catherine Finney, Jeffrey R. Curtis, Harold E. Paulus, Amy Mudano, Maria Pisu, Mary Elkins‐Melton, Ryan Outman, Jeroan J. Allison, Maria Suarez Almazor, S. Louis BridgesJr.Jr., W. Winn Chatham, Marc Hochberg, Catherine Maclean, Ted Mikuls, Larry W. Moreland, James O'dell, Anthony M. Turkiewicz & Daniel E. Furst. (2008) American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease‐modifying antirheumatic drugs in rheumatoid arthritis. Arthritis Care & Research 59:6, pages 762-784.
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Pradip Nandi, Gabrielle H Kingsley & David L Scott. (2008) Disease-modifying antirheumatic drugs other than methotrexate in rheumatoid arthritis and seronegative arthritis. Current Opinion in Rheumatology 20:3, pages 251-256.
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Edward C Keystone. (2006) Strategies to control disease in rheumatoid arthritis with tumor necrosis factor antagonists—an opportunity to improve outcomes. Nature Clinical Practice Rheumatology 2:11, pages 594-601.
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Alexander Kai-Lik So & Jonathan Kay. (2006) Preface. Best Practice & Research Clinical Rheumatology 20:4, pages 623-625.
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