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Original Article

Effect of age on response to rivastigmine or donepezil in patients with Alzheimer's disease

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Pages 483-494 | Accepted 08 Dec 2005, Published online: 27 Jan 2006

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Marion Ortner, Marion Stange, Heike Schneider, Charlotte Schröder, Katharina Buerger, Claudia Müller, Felix Müller-Sarnowski, Janine Diehl-Schmid, Hans Förstl, Timo Grimmer & Werner Steimer. (2020) Therapeutic Drug Monitoring of Rivastigmine and Donepezil Under Consideration of CYP2D6 Genotype-Dependent Metabolism of Donepezil. Drug Design, Development and Therapy 14, pages 3251-3262.
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Dana Mohammad, Parco Chan, Janelle Bradley, Krista Lanctôt & Nathan Herrmann. (2017) Acetylcholinesterase inhibitors for treating dementia symptoms - a safety evaluation. Expert Opinion on Drug Safety 16:9, pages 1009-1019.
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Nagaendran Kandiah, Ming-Chyi Pai, Vorapun Senanarong, Irene Looi, Encarnita Ampil, Kyung Won Park, Ananda Krishna Karanam & Stephen Christopher. (2017) Rivastigmine: the advantages of dual inhibition of acetylcholinesterase and butyrylcholinesterase and its role in subcortical vascular dementia and Parkinson’s disease dementia. Clinical Interventions in Aging 12, pages 697-707.
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Michael Shanks, Miia Kivipelto, Roger Bullock & Roger Lane. (2009) Cholinesterase inhibition: is there evidence for disease-modifying effects?. Current Medical Research and Opinion 25:10, pages 2439-2446.
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Norifumi Tsuno. (2009) Donepezil in the treatment of patients with Alzheimer’s disease. Expert Review of Neurotherapeutics 9:5, pages 591-598.
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Richard A Hansen, Gerald Gartlehner, Aaron P Webb, Laura C Morgan, Charity G Moore & Daniel E Jonas. (2008) Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer’s disease: A systematic review and meta-analysis. Clinical Interventions in Aging 3:2, pages 211-225.
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Ramón Cacabelos. (2007) Donepezil in Alzheimer’s disease: From conventional trials to pharmacogenetics. Neuropsychiatric Disease and Treatment 3:3, pages 303-333.
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Articles from other publishers (37)

Jill S. Chotiyanonta, Kengo Onda, Milap A. Nowrangi, Xin Li, Xin Xu, Roy Adams, Constantine G. Lyketsos, Peter Zandi & Kenichi Oishi. (2023) Translating clinical notes into quantitative measures—a real-world observation on the response to cholinesterase inhibitors or selective serotonin reuptake inhibitors prescribed to outpatients with dementia using electronic medical records. Frontiers in Pharmacology 14.
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Ezio Giacobini, A Claudio Cuello & Abraham Fisher. (2022) Reimagining cholinergic therapy for Alzheimer’s disease. Brain 145:7, pages 2250-2275.
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Natalie Argueta, Emily Notari & Kinga Szigeti. (2022) Role of Pharmacogenomics in Individualizing Treatment for Alzheimer’s Disease. CNS Drugs 36:4, pages 365-376.
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Chantal Vidal & Li Zhang. (2021) An Analysis of the Neurological and Molecular Alterations Underlying the Pathogenesis of Alzheimer’s Disease. Cells 10:3, pages 546.
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Khaled S. Abd-Elrahman, Alison Hamilton, Awatif Albaker & Stephen S. G. Ferguson. (2020) mGluR5 Contribution to Neuropathology in Alzheimer Mice Is Disease Stage-Dependent. ACS Pharmacology & Translational Science 3:2, pages 334-344.
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Patrizia Mecocci, Lucia Paolacci & Virginia Boccardi. 2020. Diagnosis and Management in Dementia. Diagnosis and Management in Dementia 457 475 .
Norifumi Tsuno, Takahiro Mori, Ichiro Ishikawa, Nobuyasu Bando, Haeyoung Park, Yoshito Matsumoto, Itsuko Mori, Mariko Tanaka, Takayuki Hirano & Yu Nakamura. (2019) Efficacy of rivastigmine transdermal therapy on low food intake in patients with Alzheimer's disease: The Attitude Towards Food Consumption in Alzheimer's Disease Patients Revive with Rivastigmine Effects study. Geriatrics & Gerontology International 19:7, pages 571-576.
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Daniela Volpato & Ulrike Holzgrabe. (2018) Designing Hybrids Targeting the Cholinergic System by Modulating the Muscarinic and Nicotinic Receptors: A Concept to Treat Alzheimer’s Disease. Molecules 23:12, pages 3230.
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Jacqueline S Birks & Richard J Harvey. (2018) Donepezil for dementia due to Alzheimer's disease. Cochrane Database of Systematic Reviews 2018:6.
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Atsushi Kuroda, Manabu Setoguchi, Yasushi Uchino, Kazuya Nagata & Daisuke Hokonohara. (2018) Effect of rivastigmine on plasma butyrylcholine esterase activity and plasma ghrelin levels in patients with dementia in Alzheimer’s disease. Geriatrics & Gerontology International 18:6, pages 886-891.
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Shigeki Hirano, Hitoshi Shinotoh, Hitoshi Shimada, Tsuneyoshi Ota, Koichi Sato, Noriko Tanaka, Ming-Rong Zhang, Makoto Higuchi, Kiyoshi Fukushi, Toshiaki Irie, Satoshi Kuwabara & Tetsuya Suhara. (2018) Voxel-Based Acetylcholinesterase PET Study in Early and Late Onset Alzheimer’s Disease. Journal of Alzheimer's Disease 62:4, pages 1539-1548.
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Seong Yoon Kim. (2018) Past and Future of Drug Treatments for Alzheimer's Disease. Journal of Korean Neuropsychiatric Association 57:1, pages 30.
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Lucy Webster, Derek Groskreutz, Anna Grinbergs-Saull, Rob Howard, John T O’Brien, Gail Mountain, Sube Banerjee, Bob Woods, Robert Perneczky, Louise Lafortune, Charlotte Roberts, Jenny McCleery, James Pickett, Frances Bunn, David Challis, Georgina Charlesworth, Katie Featherstone, Chris Fox, Claire Goodman, Roy Jones, Sallie Lamb, Esme Moniz-Cook, Justine Schneider, Sasha Shepperd, Claire Surr, Jo Thompson-Coon, Clive Ballard, Carol Brayne, Orlaith Burke, Alistair Burns, Linda Clare, Peter Garrard, Patrick Kehoe, Peter Passmore, Clive Holmes, Ian Maidment, Fliss Murtagh, Louise Robinson & Gill Livingston. (2017) Development of a core outcome set for disease modification trials in mild to moderate dementia: a systematic review, patient and public consultation and consensus recommendations. Health Technology Assessment 21:26, pages 1-192.
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Virginia Boccardi, Marta Baroni, Nicoletta Smirne, Alessandra Clodomiro, Sara Ercolani, Annalisa Longo, Carmelinda Ruggiero, Amalia C. Bruni & Patrizia Mecocci. (2017) Short-Term Response is not Predictive of Long-Term Response to Acetylcholinesterase Inhibitors in Old Age Subjects with Alzheimer’s Disease: A “Real World” Study. Journal of Alzheimer's Disease 56:1, pages 239-248.
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Louis De Beaumont, Sandra Pelleieux, Louise Lamarre-Théroux, Doris Dea & Judes Poirier. (2016) Butyrylcholinesterase K and Apolipoprotein E-ɛ4 Reduce the Age of Onset of Alzheimer’s Disease, Accelerate Cognitive Decline, and Modulate Donepezil Response in Mild Cognitively Impaired Subjects. Journal of Alzheimer's Disease 54:3, pages 913-922.
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Hiroaki Kazui, Kenji Yoshiyama, Hideki Kanemoto, Yukiko Suzuki, Shunsuke Sato, Mamoru Hashimoto, Manabu Ikeda, Hibiki Tanaka, Yutaka Hatada, Masateru Matsushita, Yoshiyuki Nishio, Etsuro Mori, Satoshi Tanimukai, Kenjiro Komori, Taku Yoshida, Hideaki Shimizu, Teruhisa Matsumoto, Takaaki Mori, Tetsuo Kashibayashi, Kazumasa Yokoyama, Tatsuo Shimomura, Yasunobu Kabeshita, Hiroyoshi Adachi & Toshihisa Tanaka. (2016) Differences of Behavioral and Psychological Symptoms of Dementia in Disease Severity in Four Major Dementias. PLOS ONE 11:8, pages e0161092.
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Jacqueline S Birks, Lee-Yee Chong & John Grimley Evans. (2015) Rivastigmine for Alzheimer's disease. Cochrane Database of Systematic Reviews.
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Alireza Atri & Theodore A. Stern. (2015) Psychopharmacologic Agents to Enhance Cognition in Alzheimer’s Disease. Psychiatric Annals 45:7.
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David Riascos, Alexander Nicholas, Ravand Samaeekia, Rustam Yukhananov, M.-Marsel Mesulam, Eileen H. Bigio, Sandra Weintraub, Ling Guo & Changiz Geula. (2014) Alterations of Ca2+-responsive proteins within cholinergic neurons in aging and Alzheimer's disease. Neurobiology of Aging 35:6, pages 1325-1333.
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