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Original Article

Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure*

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Pages 683-689 | Accepted 24 Jan 2007, Published online: 20 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (10)

Anton Hommer. (2011) Role of fixed combinations in the management of open-angle glaucoma. Expert Review of Pharmacoeconomics & Outcomes Research 11:1, pages 91-99.
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Julián García-Feijoó, Federico Sáenz-Francés, José María Martínez-de-la-Casa, Carmen Méndez-Hernández, Ana Fernández-Vidal, Cristina Calvo-González & Julián García-Sánchez. (2010) Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol. Current Medical Research and Opinion 26:7, pages 1599-1606.
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Dimitris Papaconstantinou, Ilias Georgalas, Nikolaos Kourtis, Christos Pitsas, Efthimios Karmiris, Chrysanthi Koutsandrea, Ioannis Ladas & Gerasimos Georgopoulos. (2009) Preliminary results following the use of a fixed combination of timolol–brimonidine in patients with ocular hypertension and primary open-angle glaucoma. Clinical Ophthalmology 3, pages 227-230.
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Donald R. Nixon, David B. Yan, Jean-Pierre Chartrand, Roberto L. Piemontesi, Susan Simonyi & David A. Hollander. (2009) Three-month, randomized, parallel-group comparison of brimonidine–timolol versus dorzolamide–timolol fixed-combination therapy. Current Medical Research and Opinion 25:7, pages 1645-1653.
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Jason Yeh, Daniel Kravitz & Brian Francis. (2008) Rational use of the fixed combination of dorzolamide – timolol in the management of raised intraocular pressure and glaucoma. Clinical Ophthalmology 2:2, pages 389-399.
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L. Jay Katz, Steven T. Simmons & E. Randy Craven. (2007) Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension. Current Medical Research and Opinion 23:12, pages 2971-2983.
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Articles from other publishers (13)

Masaru Inatani, Yusuke Orii, Kentaro Iwasaki, Shogo Arimura, Hiromi Sunagawa, Minako Shiokawa, Kenji Inoue, Takuto Sakono, Takato Sakono, Rika Kuwamura, Akiko Yoshida, Junko Oi, Yasuaki Kuwayama, Kiyoshi Kano, Noriaki Kido, Akiko Matsuyama, Mineo Ozaki, Hideki Abe, Chizuru Inoue, Satoko Nakagawa, Kunihiro Musashi, Akiyasu Kanamori, Jinhee Lee, Shinichiro Otani, Ryota Aoki, Hirotaka Tanabe, Shunsuke Nakakura, Katsuyoshi Suzuki, Takeshi Sagara, Yoshiaki Saito, Motoyasu Sameshima, Mai Urahashi, Fumika Watanabe-Kitamura, Toshihiro Inoue, Fumie Kagaya, Yusuke Murai, Sotaro Mori, Kaori Ueda, Takuji Kurimoto, Yuko Yamada-Nakanishi, Makoto Nakamura, Takehiro Yamashita, Sosuke Ishiyama, Shinichi Manabe, Keiko Takaki, Ken Hayashi, Akiko Ishida, Aika Tsutsui, Kaoru Manabe & Masaki Tanito. (2023) Randomized Multicenter Clinical Trial Comparing 0.1% Brimonidine/0.5% Timolol Versus 1% Dorzolamide/0.5% Timolol as Adjuncts to Prostaglandin Analogues: Aibeta Crossover Study. Advances in Therapy 40:9, pages 4074-4092.
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Ali bigdeli, Behzad Sharif Makhmalzadeh, Mostafa Feghhi & Emad SoleimaniBiatiani. (2022) Cationic liposomes as promising vehicles for timolol/brimonidine combination ocular delivery in glaucoma: formulation development and in vitro/in vivo evaluation. Drug Delivery and Translational Research 13:4, pages 1035-1047.
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Elissavet Taka, Christina Karavasili, Nikolaos Bouropoulos, Thomas Moschakis, Dimitrios D. Andreadis, Constantinos K. Zacharis & Dimitrios G. Fatouros. (2020) Ocular Co-Delivery of Timolol and Brimonidine from a Self-Assembling Peptide Hydrogel for the Treatment of Glaucoma: In Vitro and Ex Vivo Evaluation. Pharmaceuticals 13:6, pages 126.
Crossref
Göktuğ Seymenoğlu, Esin F. Baser, Bilge Öztürk & Ceren Gülhan. (2015) Comparison of Dorzolamide/Timolol Versus Brimonidine/Timolol Fixed Combination Therapy in the Management of Steroid-Induced Ocular Hypertension. Journal of Glaucoma 24:2, pages 111-116.
Crossref
Anastasios GP Konstas, Luciano Quaranta, Andreas Katsanos, Irini C Voudouragkaki & Gordon N Dutton. 2015. Glaucoma. Glaucoma 583 592 .
Anastasios G. P. KonstasGábor HollóAnna-Bettina HaidichDimitrios G. MikropoulosTheodoros GiannopoulosIrini C. VoudouragkakiEleni PaschalinouVassilios KonidarisJohn R. Samples. (2013) Comparison of 24-Hour Intraocular Pressure Reduction Obtained with Brinzolamide/Timolol or Brimonidine/Timolol Fixed-Combination Adjunctive to Travoprost Therapy. Journal of Ocular Pharmacology and Therapeutics 29:7, pages 652-657.
Crossref
Patrick BudengeriJin-Wei ChengJi-Ping CaiRui-Li Wei. (2013) Efficacy and Tolerability of Fixed Combination of Brimonidine 0.2%/Timolol 0.5% Compared with Fixed Combination of Dorzolamide 2%/Timolol 0.5% in the Treatment of Patients with Elevated Intraocular Pressure: A Meta-Analysis of Randomized Controlled Trials. Journal of Ocular Pharmacology and Therapeutics 29:5, pages 474-479.
Crossref
A G P Konstas, L Quaranta, D B Yan, D G Mikropoulos, I Riva, N K Gill, K Barton & A-B Haidich. (2011) Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle glaucoma. Eye 26:1, pages 80-87.
Crossref
Gokhan Gulkilik, Ersin Oba & Mahmut Odabası. (2011) Comparison of fixed combinations of dorzolamide/timolol and brimonidine/timolol in patients with primary open-angle glaucoma. International Ophthalmology 31:6, pages 447-451.
Crossref
Quang H. NguyenMelissa Earl. (2009) Fixed-Combination Brimonidine/Timolol as Adjunctive Therapy to a Prostaglandin Analog: A 3-Month, Open-Label, Replacement Study in Glaucoma Patients. Journal of Ocular Pharmacology and Therapeutics 25:6, pages 541-544.
Crossref
Robert L Stamper, Marc F Lieberman & Michael V Drake. 2009. Becker-Shaffer's Diagnosis and Therapy of the Glaucomas. Becker-Shaffer's Diagnosis and Therapy of the Glaucomas 376 391 .
Marcelo Hatanaka, Daniel E. Grigera, Wilma L. Barbosa, Marcelo Jordao & Remo Susanna. (2008) An Eight-week, Multicentric, Randomized, Interventional, Open-label, Phase 4, Parallel Comparison of the Efficacy and Tolerability of the Fixed Combination of Timolol Maleate 0.5%/Brimonidine Tartrate 0.2% Versus Fixed Combination of Timolol Maleate 0.5%/Dorzolamide 2% in Patients With Elevated Intraocular Pressure. Journal of Glaucoma 17:8, pages 674-679.
Crossref
A. Hommer, J. Thygesen, A. Ferreras, J. Wickstrøm, M.M. Friis, P. Buchholz & J.G. Walt. (2018) A European Perspective on Costs and Cost Effectiveness of Ophthalmic Combinations in the Treatment of Open-Angle Glaucoma. European Journal of Ophthalmology 18:5, pages 778-786.
Crossref

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