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Original Article

A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain

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Pages 1551-1561 | Accepted 07 Apr 2009, Published online: 18 May 2009

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Read on this site (29)

Estelle Watson, Akash Khandelwal, Jan Freijer, John van den Anker, Claudia Lefeber & Mariëlle Eerdekens. (2019) Population pharmacokinetic modeling to facilitate dose selection of tapentadol in the pediatric population. Journal of Pain Research 12, pages 2835-2850.
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Derek Muse, Eva Tarau, Claudia Lefeber, Melanie Sohns, Martin Brett, Jutta Goldberg & Ronald Rosenburg. (2019) Pharmacokinetics, safety, and efficacy of tapentadol oral solution for treating moderate to severe pain in pediatric patients. Journal of Pain Research 12, pages 1777-1790.
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Joseph V. Pergolizzi$suffix/text()$suffix/text(), Jo Ann LeQuang, Robert Taylor$suffix/text()$suffix/text(), Michael H. Ossipov, Daniel Colucci & Robert B. Raffa. (2018) Designing safer analgesics: a focus on μ-opioid receptor pathways. Expert Opinion on Drug Discovery 13:10, pages 965-972.
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Laura E. Gressler, Drayton A. Hammond & Jacob T. Painter. (2017) Serotonin Syndrome in Tapentadol Literature: Systematic Review of Original Research. Journal of Pain & Palliative Care Pharmacotherapy 31:3-4, pages 228-236.
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Bruce D Nicholson. (2017) Economic and clinical burden of opioid-induced nausea and vomiting. Postgraduate Medicine 129:1, pages 111-117.
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M. Förster, S. Helfert, R. Dierschke, M. Großkopf, P. Hüllemann, T. Keller, R. Baron & A. Binder. (2016) Evaluation of the antihyperalgesic effect of tapentadol in two human evoked pain models – the TapCapMentho pilot trial. Expert Opinion on Pharmacotherapy 17:13, pages 1717-1725.
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Yeung-Jen Chen, Chao-Ching Chiang, Peng-Ju Huang, Jason Huang, Keith Karcher & Honglan Li. (2015) Tapentadol immediate-release for acute postbunionectomy pain: a phase 3, randomized, double-blind, placebo-controlled, parallel-group study in Taiwan. Current Medical Research and Opinion 31:11, pages 2001-2009.
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Y. K. Lee, J. S. Ko, H. Y. Rhim, E. J. Lee, K. Karcher, H. Li, D. Shapiro & H. S. Lee. (2014) Acute postoperative pain relief with immediate-release tapentadol: randomized, double-blind, placebo-controlled study conducted in South Korea. Current Medical Research and Opinion 30:12, pages 2561-2570.
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Joseph V. Pergolizzi$suffix/text()$suffix/text(), Marco Pappagallo, JoAnn LeQuang, Sumedha Labhsetwar & Robert Taylor$suffix/text()$suffix/text(). (2014) New Health Care Measures: Emphasis on Better Management of Postsurgical Pain and Postoperative Nausea and Vomiting. Hospital Practice 42:1, pages 65-74.
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Nalini Vadivelu, Yili Huang, Brian Mirante, Michael Jacoby, Ferne R Braveman, Roberta L Hines & Raymond Sinatra. (2013) Patient considerations in the use of tapentadol for moderate to severe pain. Drug, Healthcare and Patient Safety 5, pages 151-159.
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Roy Altman, Stephen Daniels & Clarence L. Young. (2013) Indomethacin Submicron Particle Capsules Provide Effective Pain Relief in Patients with Acute Pain: A Phase 3 Study. The Physician and Sportsmedicine 41:4, pages 7-15.
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Allan Gibofsky, Stephen Silberstein, Charles Argoff, Stephen Daniels, Steve Jensen & Clarence L. Young. (2013) Lower-Dose Diclofenac Submicron Particle Capsules Provide Early and Sustained Acute Patient Pain Relief in a Phase 3 Study. Postgraduate Medicine 125:5, pages 130-138.
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Jay Lin, Wing Chow, Myoung S. Kim & Marcia F. T. Rupnow. (2013) Real-world treatment pattern and outcomes among patients who took tapentadol IR or oxycodone IR. Journal of Medical Economics 16:5, pages 685-690.
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Stephen E. Daniels, Ron J. Spivey, Sonia Singla, Michael Golf & Francis J. Clark. (2011) Efficacy and safety of oxycodone HCl/niacin tablets for the treatment of moderate-to-severe postoperative pain following bunionectomy surgery. Current Medical Research and Opinion 27:3, pages 593-603.
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Marc Afilalo, Jens-Ulrich Stegmann & David Upmalis. (2010) Tapentadol immediate release: a new treatment option for acute pain management. Journal of Pain Research 3, pages 1-9.
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Robert Buynak, Douglas Y Shapiro, Akiko Okamoto, Ilse Van Hove, Christine Rauschkolb, Achim Steup, Bernd Lange, Claudia Lange & Mila Etropolski. (2010) Efficacy and safety of tapentadol extended release for the management of chronic low back pain: results of a prospective, randomized, double-blind, placebo- and active-controlled Phase III study. Expert Opinion on Pharmacotherapy 11:11, pages 1787-1804.
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Craig T Hartrick. (2010) Tapentadol immediate-release for acute pain. Expert Review of Neurotherapeutics 10:6, pages 861-869.
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Craig T Hartrick. (2009) Tapentadol immediate release for the relief of moderate-to-severe acute pain. Expert Opinion on Pharmacotherapy 10:16, pages 2687-2696.
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