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Review

The effect of pregabalin on pain-related sleep interference in diabetic peripheral neuropathy or postherpetic neuralgia: a review of nine clinical trials

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Pages 2411-2419 | Accepted 13 Aug 2010, Published online: 02 Sep 2010

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Rainer Freynhagen, Ralf Baron, Yoshiharu Kawaguchi, Rayaz A. Malik, Diane L. Martire, Bruce Parsons, Roberto D. Rey, Stephan A. Schug, Troels Staehelin Jensen, Thomas R. Tölle, Takahiro Ushida & Ed Whalen. (2021) Pregabalin for neuropathic pain in primary care settings: recommendations for dosing and titration. Postgraduate Medicine 133:1, pages 1-9.
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Bruce Parsons & Chunming Li. (2016) The efficacy of pregabalin in patients with moderate and severe pain due to diabetic peripheral neuropathy. Current Medical Research and Opinion 32:5, pages 929-937.
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Toshihiko Taguchi, Ataru Igarashi, Stephen Watt, Bruce Parsons, Alesia Sadosky, Kazutaka Nozawa, Kazuhiro Hayakawa, Tamotsu Yoshiyama, Nozomi Ebata & Koichi Fujii. (2015) Effectiveness of pregabalin for the treatment of chronic low back pain with accompanying lower limb pain (neuropathic component): a non-interventional study in Japan. Journal of Pain Research 8, pages 487-497.
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Miguel A Ruiz, Enrique Álvarez, Jose L Carrasco, José M Olivares, María Pérez & Javier Rejas. (2015) Modeling the longitudinal latent effect of pregabalin on self-reported changes in sleep disturbances in outpatients with generalized anxiety disorder managed in routine clinical practice. Drug Design, Development and Therapy 9, pages 4329-4340.
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Mark S. Juhn, Bruce Parsons, Roxanna Varvara & Alesia Sadosky. (2015) Pregabalin for painful diabetic peripheral neuropathy: strategies for dosing, monotherapy vs. combination therapy, treatment-refractory patients, and adverse events. Current Medical Research and Opinion 31:5, pages 1017-1026.
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Mohsen Saheban Maleki, Zahra Zamani, Roya Amiri, Samaneh Kakhki, Mojtaba Jafari, Behnam Amani, Bahman Amani & Nasir Amanat. (2023) Pregabalin in patients with post‐traumatic peripheral neuropathic pain: A meta‐analysis of randomized controlled trials . Pain Practice 23:6, pages 595-602.
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Loretta Vileikyte & Frans Pouwer. 2023. Diabetic Neuropathy. Diabetic Neuropathy 221 236 .
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Yonggang Xie, Zhen Li, Hongyu Xu, Jiahai Ma, Tao Li, Cunxian Shi & Jin Jin. (2022) Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice. ACS Chemical Neuroscience 13:9, pages 1446-1455.
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Daniela C. Rosenberger, Vivian Blechschmidt, Hans Timmerman, André Wolff & Rolf-Detlef Treede. (2020) Challenges of neuropathic pain: focus on diabetic neuropathy. Journal of Neural Transmission 127:4, pages 589-624.
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Basak Altiparmak, Hemra Cil & Nalan Celebi. (2019) Effect of melatonin on the daytime sleepiness side-effect of gabapentin in adults patients with neuropathic pain. Brazilian Journal of Anesthesiology (English Edition) 69:2, pages 137-143.
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Basak Altiparmak, Hemra Cil & Nalan Celebi. (2019) Efeito da melatonina sobre o efeito colateral de sonolência diurna da gabapentina em pacientes adultos com dor neuropática. Brazilian Journal of Anesthesiology 69:2, pages 137-143.
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Shazli Azmi, Kariem T. ElHadd, Andrew Nelson, Adam Chapman, Frank L. Bowling, Anughara Perumbalath, Jonathan Lim, Andrew Marshall, Rayaz A. Malik & Uazman Alam. (2018) Pregabalin in the Management of Painful Diabetic Neuropathy: A Narrative Review. Diabetes Therapy 10:1, pages 35-56.
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Joan L. Shaver & Stella Iacovides. (2018) Sleep in Women with Chronic Pain and Autoimmune Conditions. Sleep Medicine Clinics 13:3, pages 375-394.
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Luigi Ferini-Strambi. (2017) Neuropathic Pain and Sleep: A Review. Pain and Therapy 6:S1, pages 19-23.
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Galit Almoznino, Rafael Benoliel, Yair Sharav & Yaron Haviv. (2017) Sleep disorders and chronic craniofacial pain: Characteristics and management possibilities. Sleep Medicine Reviews 33, pages 39-50.
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Quanzhong Liu, Haibo Chen, Liyan Xi, Zhen Hong, Li He, Yi Fu, Hong Fang, Ningxiu Shang, Ping Yan & Dongsheng Fan. (2017) A Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Pregabalin for Postherpetic Neuralgia in a Population of Chinese Patients. Pain Practice 17:1, pages 62-69.
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Andreas Binder, Peter Rogers, Guy Hans & Ralf Baron. (2016) Impact of topical 5% lidocaine-medicated plasters on sleep and quality of life in patients with postherpetic neuralgia. Pain Management 6:3, pages 229-239.
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Marlene Schrimpf, Gregor Liegl, Markus Boeckle, Anton Leitner, Peter Geisler & Christoph Pieh. (2015) The effect of sleep deprivation on pain perception in healthy subjects: a meta-analysis. Sleep Medicine 16:11, pages 1313-1320.
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Brigitte A. Brouwer, Bianca T. A. de Greef, Janneke G. J. Hoeijmakers, Margot Geerts, Maarten van Kleef, Ingemar S. J. Merkies & Catharina G. Faber. (2015) Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects. Drugs & Aging 32:8, pages 611-621.
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Lesley M. Arnold, Birol Emir, Lynne Pauer, Malca Resnick & Andrew Clair. (2015) Time to Improvement of Pain and Sleep Quality in Clinical Trials of Pregabalin for the Treatment of Fibromyalgia. Pain Medicine 16:1, pages 176-185.
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Miqdad H Bohra, Chhavi Kaushik, Daniel Temple, Sharon A Chung & Colin M Shapiro. (2014) Weighing the balance: how analgesics used in chronic pain influence sleep?. British Journal of Pain 8:3, pages 107-118.
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Mehtap Bozkurt, Cuneyt Gocmez, Haluk Soylemez, Mansur Daggulli, Serda Em, Mehmet Yildiz, Murat Atar, Yasar Bozkurt & Isa Ozbey. (2014) Association Between Neuropathic Pain, Pregabalin Treatment, and Erectile Dysfunction. The Journal of Sexual Medicine 11:7, pages 1816-1822.
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Emilio Blanco Tarrio, Rafael Gálvez Mateos, Enric Zamorano Bayarri, Vanessa López Gómez & Maria Pérez Páramo. (2013) Effectiveness of Pregabalin as Monotherapy or Combination Therapy for Neuropathic Pain in Patients Unresponsive to Previous Treatments in a Spanish Primary Care Setting. Clinical Drug Investigation 33:9, pages 633-645.
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Stephen M. Stahl, Frank Porreca, Charles P. Taylor, Raymond Cheung, Andrew J. Thorpe & Andrew Clair. (2013) The diverse therapeutic actions of pregabalin: is a single mechanism responsible for several pharmacological activities?. Trends in Pharmacological Sciences 34:6, pages 332-339.
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Zeynep Biyik, Yalcin Solak, Huseyin Atalay, Abduzhappar Gaipov, Figen Guney & Suleyman Turk. (2012) Gabapentin versus pregabalin in improving sleep quality and depression in hemodialysis patients with peripheral neuropathy: a randomized prospective crossover trial. International Urology and Nephrology 45:3, pages 831-837.
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Edith Holsboer-Trachsler & Rita Prieto. (2013) Effects of pregabalin on sleep in generalized anxiety disorder. International Journal of Neuropsychopharmacology 16:4, pages 925-936.
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Mary J. Eaton, Yerko Berrocal & Stacey Q. Wolfe. (2012) Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines. Pain Research and Treatment 2012, pages 1-31.
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Santiago Perez-Lloret, Gloria Meza Rojas, Maria Celia Menoni, Gabriela Ruiz, Carolina Velásquez, Hernán Rodriguez, María Verónica Rey & Daniel P. Cardinali. (2012) Pregabalin Beneficial Effects on Sleep Quality or Health-Related Quality of Life Are Poorly Correlated With Reduction on Pain Intensity After an 8-Week Treatment Course. Clinical Neuropharmacology 35:1, pages 21-24.
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Emmanouil Anastassiou, Christos A. Iatrou, Nikolaos Vlaikidis, Marianthi Vafiadou, Georgia Stamatiou, Eleni Plesia, Leonidas Lyras & Athina Vadalouca. (2011) Impact of Pregabalin Treatment on Pain, Pain-Related Sleep Interference and General Well-Being in Patients with Neuropathic Pain. Clinical Drug Investigation 31:6, pages 417-426.
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