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Original Article

Long-term effectiveness and tolerability of sublingual fentanyl orally disintegrating tablet for the treatment of breakthrough cancer pain

, , , , &
Pages 519-530 | Accepted 02 Dec 2010, Published online: 06 Jan 2011

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Read on this site (5)

Andrew Chang, Eric J. Roeland, Rabia S. Atayee, Carolyn Revta & Joseph D. Ma. (2015) Transmucosal Immediate-Release Fentanyl for Breakthrough Cancer Pain: Opportunities and Challenges for Use in Palliative Care. Journal of Pain & Palliative Care Pharmacotherapy 29:3, pages 247-260.
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Charles E. Argoff & Ernest A. Kopecky. (2014) Patients with chronic pain and dysphagia (CPD): unmet medical needs and pharmacologic treatment options. Current Medical Research and Opinion 30:12, pages 2543-2559.
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Howard S Smith. (2013) Considerations in selecting rapid-onset opioids for the management of breakthrough pain. Journal of Pain Research 6, pages 189-200.
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Richard Rauck, Lowell Reynolds, Jonathan Geach, Janet Bull, Lisa Stearns, Morris Scherlis, Neha Parikh & Larry Dillaha. (2012) Efficacy and safety of fentanyl sublingual spray for the treatment of breakthrough cancer pain: a randomized, double-blind, placebo-controlled study. Current Medical Research and Opinion 28:5, pages 859-870.
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Michael A. Überall & Gerhard H.H. Müller-Schwefe. (2011) Sublingual fentanyl orally disintegrating tablet in daily practice: efficacy, safety and tolerability in patients with breakthrough cancer pain. Current Medical Research and Opinion 27:7, pages 1385-1394.
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Articles from other publishers (30)

Paolo Bossi, Yolanda Escobar & Federico Pea. (2022) Rapid-Onset Opioids for Management of Breakthrough Cancer Pain: Considerations for Daily Practice. Frontiers in Pain Research 3.
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. 2022. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 511 774 .
Youn Seon Choi, Su-Jin Koh, Woo Kyun Bae, Se Hyung Kim, Seong Hoon Shin, So Yeon Oh, Sang Byung Bae, Yaewon Yang, Eun-Kee Song, Yoon Young Cho, Pyung Bok Lee, Ho-Suk Oh, Sang Won Park & Jin Seok Ahn. (2021) Observational study of efficacy, safety, and tolerability of fentanyl in Korean cancer patients (OASIS). Medicine: Case Reports and Study Protocols 2:3, pages e0088.
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Hojun Song, Cheol Moon, Beom-Jin Lee & Euichaul Oh. (2018) Mesoporous Pravastatin Solid Dispersion Granules Incorporable Into Orally Disintegrating Tablets. Journal of Pharmaceutical Sciences 107:7, pages 1886-1895.
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Eberhard Albert Lux, Andreas Schwittay, Ulrich R. Kleeberg & Jens Papke. (2018) Fentanyl-Buccaltabletten in der Behandlung von DurchbruchschmerzenFentanyl buccal tablets in the treatment of breakthrough cancer pain. German cohort of a pan-European multicentre study. MMW - Fortschritte der Medizin 160:S4, pages 18-23.
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Jordi Guitart, María Isabel Vargas, Vicente De Sanctis, Jordi Folch, Rafael Salazar, José Fuentes, Joan Coma, Julia Ferreras, Jordi Moya, Albert Tomás, Pere Estivill, Francisco Rodelas, Antonio Javier Jiménez & Almudena Sanz. (2018) Efficacy and Safety of Sublingual Fentanyl Tablets in Breakthrough Cancer Pain Management According to Cancer Stage and Background Opioid Medication. Drugs in R&D 18:2, pages 119-128.
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Robert Janknegt, Marieke van den Beuken, Sjouke Schiere, Michael Überall, Roger Knaggs, Jaquie Hanley & Morten Thronaes. (2018) Rapid acting fentanyl formulations in breakthrough pain in cancer. Drug selection by means of the System of Objectified Judgement Analysis. European Journal of Hospital Pharmacy 25:3, pages e2-e2.
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. 2018. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 447 696 .
Michael A. Überall. (2017) Transmukosale Applikation von Fentanyl: sublingual, buccal, nasal — egal?Transmucosal fentanyl administration: sublingual, buccal, nasal — all the same? Treatment of breakthrough cancer pain. MMW - Fortschritte der Medizin 159:S6, pages 15-22.
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Jeannine Brant, Barbara Rodgers, Eva Gallagher & Thiruppavai Sundaramurthi. (2017) Breakthrough Cancer Pain: A Systematic Review of Pharmacologic Management
. Clinical Journal of Oncology Nursing 21:3, pages 71-80.
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Saadya A. Tayel, Mohamed A. El Nabarawi, Maha M. Amin & Mohamed H. H. AbouGhaly. (2016) Comparative Study Between Different Ready-Made Orally Disintegrating Platforms for the Formulation of Sumatriptan Succinate Sublingual Tablets. AAPS PharmSciTech 18:2, pages 410-423.
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Harold Minkowitz, Janet Bull, R. Charles Brownlow, Neha Parikh & Richard Rauck. (2016) Long-term safety of fentanyl sublingual spray in opioid-tolerant patients with breakthrough cancer pain. Supportive Care in Cancer 24:6, pages 2669-2675.
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Jordi Guitart, María Isabel Vargas, Vicente De Sanctis, Jordi Folch, Rafael Salazar, José Fuentes, Jordi Coma, Julia Ferreras, Jordi Moya, Albert Tomás, Pere Estivill, Francisco Rodelas & Antonio Javier Jiménez. (2015) Sublingual Fentanyl Tablets for Relief of Breakthrough Pain in Cancer Patients and Association with Quality-of-Life Outcomes. Clinical Drug Investigation 35:12, pages 815-822.
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Andrew Davies, Ulrich R. Kleeberg, Jerzy Jarosz, Sebastiano Mercadante, Philippe Poulain, Tony O’Brien, Hélène Schneid & Hans G. Kress. (2015) Improved patient functioning after treatment of breakthrough cancer pain: an open-label study of fentanyl buccal tablet in patients with cancer pain. Supportive Care in Cancer 23:7, pages 2135-2143.
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Morten Thronæs, Lars Popper, Martin Eeg, Ellen Jaatun, Magnar Kvitberg & Stein Kaasa. (2015) Efficacy and Tolerability of Intranasal Fentanyl Spray in Cancer Patients With Breakthrough Pain. Clinical Therapeutics 37:3, pages 585-596.
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Luz Cánovas-Martínez, José J. Carceller-Ruiz, Pilar Díaz-Parada, Gustavo Illodo-Miramontes, Enrique Freire-Vila, Aurora De la Iglesia-López, Belén García Iglesias, Beatriz López-Ulloa, Enrique Domínguez-Suárez & Alberto Camba-Rodríguez. (2015) Efficacy and Safety of Sublingual Fentanyl Tablets for the Management of Breakthrough Pain in Patients with Chronic Musculoskeletal Pain with Neuropathic Component: Multicenter Prospective Study. Clinical Drug Investigation 35:3, pages 169-177.
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C. Takigawa, F. Goto, S. Tanda, Y. Shima, K. Yomiya, M. Matoba, I. Adachi, T. Yoshimoto & K. Eguchi. (2014) Breakthrough pain management using fentanyl buccal tablet (FBT) in combination with around-the-clock (ATC) opioids based on the efficacy and safety of FBT, and its relationship with ATC opioids: results from an open-label, multi-center study in Japanese cancer patients with detailed evaluation. Japanese Journal of Clinical Oncology 45:1, pages 67-74.
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. 2015. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 417 651 .
Ignacio Velázquez Rivera, José Carlos Muñoz Garrido, Pilar García Velasco, Inmaculada España Ximénez de Enciso & Lourdes Velázquez Clavarana. (2014) Efficacy of Sublingual Fentanyl vs. Oral Morphine for Cancer-Related Breakthrough Pain. Advances in Therapy 31:1, pages 107-117.
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Srinivas Nalamachu. (2013) An Evaluation of Total Disintegration Time for Three Different Doses of Sublingual Fentanyl Tablets in Patients with Breakthrough Pain. Pain and Therapy 2:2, pages 121-128.
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Jordi Guitart, Isabel Vargas, Vicente De Sanctis, Julia Ferreras, Jose Fuentes, Rafael Salazar, Juan M. Vázquez, Jordi Folch, Jordi Moya, Hermann Ribera, Francisco Rodelas, Albert Tomás, María Arilla, Joan Coma, Teresa Aberasturi, Dolores Sintes & Ester Lombán. (2013) Efficacy and Safety of Sublingual Fentanyl Orally Disintegrating Tablets in Patients with Breakthrough Pain: Multicentre Prospective Study. Clinical Drug Investigation 33:9, pages 675-683.
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Donald R TaylorDonald Taylor. 2013. Managing Cancer Breakthrough Pain. Managing Cancer Breakthrough Pain 29 66 .
Srinivas R. Nalamachu, Richard L. Rauck, Mark S. Wallace, David Hassman & Julian Howell. (2012) Successful Dose Finding with Sublingual Fentanyl Tablet: Combined Results from 2 Open‐Label Titration Studies. Pain Practice 12:6, pages 449-456.
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Robert Twycross, Eric E. Prommer, Mary Mihalyo & Andrew Wilcock. (2012) Fentanyl (transmucosal). Journal of Pain and Symptom Management 44:1, pages 131-149.
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Howard Smith. (2012) A Comprehensive Review of Rapid-Onset Opioids for Breakthrough Pain. CNS Drugs 26:6, pages 509-535.
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Allen W. Burton, Perry G. Fine & Steven D. Passik. (2012) Transformation of Acute Cancer Pain to Chronic Cancer Pain Syndromes. The Journal of Supportive Oncology 10:3, pages 89-95.
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. (2012) Current World Literature. Current Opinion in Supportive & Palliative Care 6:1, pages 109-125.
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Yoshifumi Murata, Kyoko Kofuji, Norihisa Nishida & Ryosei Kamaguchi. (2012) Development of Film Dosage Form Containing Allopurinol for Prevention and Treatment of Oral Mucositis. ISRN Pharmaceutics 2012, pages 1-5.
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Yoshifumi Murata, Takashi Isobe, Kyoko Kofuji, Masafumi Mizutani & Ryosei Kamaguchi. (2012) Development of Oral Dissolving Gelatin Beads Containing Allopurinol for the Prevention and Treatment of Mucositis. Pharmacology & Pharmacy 03:03, pages 295-299.
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&NA;. (2011) Fentanyl sublingual tablet: a guide to its use in breakthrough pain in opioid-tolerant adults with cancer. Drugs & Therapy Perspectives 27:7, pages 6-9.
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