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Original Article

The safety and efficacy of alcaftadine 0.25% ophthalmic solution for the prevention of itching associated with allergic conjunctivitis

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Pages 623-631 | Accepted 14 Dec 2010, Published online: 21 Jan 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Joseph B Ciolino, Eugene B McLaurin, Nicholas P Marsico, Stacey L Ackerman, Julia M Williams, Linda Villanueva & David A Hollander. (2015) Effect of alcaftadine 0.25% on ocular itch associated with seasonal or perennial allergic conjunctivitis: a pooled analysis of two multicenter randomized clinical trials. Clinical Ophthalmology 9, pages 765-772.
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DeGaulle I Chigbu & Alissa M Coyne. (2015) Update and clinical utility of alcaftadine ophthalmic solution 0.25% in the treatment of allergic conjunctivitis. Clinical Ophthalmology 9, pages 1215-1225.
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Paramdeep S Bilkhu, Shehzad A Naroo & James S Wolffsohn. (2015) Treatment of ocular allergies: nonpharmacologic, pharmacologic and immunotherapy. Expert Review of Ophthalmology 10:3, pages 257-266.
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Erminia Ridolo, Marcello Montagni, Marco Caminati, Gianenrico Senna, Cristoforo Incorvaia & Giorgio Walter Canonica. (2014) Emerging drugs for allergic conjunctivitis. Expert Opinion on Emerging Drugs 19:2, pages 291-302.
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Stacey Ackerman, Francis D’Ambrosio$suffix/text()$suffix/text(), Jack V Greiner, Linda Villanueva, Joseph B Ciolino & David A Hollander. (2013) A multicenter evaluation of the efficacy and duration of action of alcaftadine 0.25% and olopatadine 0.2% in the conjunctival allergen challenge model. Journal of Asthma and Allergy 6, pages 43-52.
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Annabelle C Gallois-Bernos & Robin L Thurmond. (2012) Alcaftadine, a new antihistamine with combined antagonist activity at histamine H1, H2, and H4 receptors. Journal of Receptor, Ligand and Channel Research 5, pages 9-20.
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Articles from other publishers (23)

Anand M. Lahoti, Narendra B. Ambhaikar, D.M. Rajagopal Reddy, Arnab Roy, Kallam V.S.R. Krishna Reddy & S. Mahender Rao. (2022) Investigation of Alcaftadine using a Double Oxidation Process by Eliminating Column Chromatography. Asian Journal of Chemistry 34:6, pages 1431-1438.
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Eugene B. McLaurin, David Evans, Carolyn S. Repke, Michelle A. Sato, Paul J. Gomes, Erin Reilly, Nysha Blender, Fabiana Q. Silva, Srilatha Vantipalli, Jamie L. Metzinger, Andrea Gibson & Michael H. Goldstein. (2021) Phase 3 Randomized Study of Efficacy and Safety of a Dexamethasone Intracanalicular Insert in Patients With Allergic Conjunctivitis. American Journal of Ophthalmology 229, pages 288-300.
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Sawsan A. Abdel Razeq, Shimaa E. Abdel Aziz & Nermin S. Ahmed. (2021) Stability-indicating UPLC, TLC-densitometric and UV-spectrophotometric methods for alcaftadine determination. Journal of Chromatography B 1177, pages 122804.
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Snigdha Sen, Himanshu Kumar Yadav & Prerana Singh. (2020) A Comparative Study of Efficacy of Alcaftadine 0.25 % and Olopatadine 0.2 % in Allergic Conjunctivitis. Journal of Evidence Based Medicine and Healthcare 7:52, pages 3153-3158.
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Jae Hyuk Kim, Hyun Joon Kim & Sun Woong Kim. (2019) Allergic contact dermatitis of both eyes caused by alcaftadine 0.25%: a case report. BMC Ophthalmology 19:1.
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DeGaulle I. Chigbu & Bhawanjot K. Minhas. (2018) Immunopathology of Allergic Conjunctivitis. European Medical Journal, pages 76-83.
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Hyungbin Hwang. (2017) Pathogenesis of allergic conjunctivitis and trends in its treatment. Journal of the Korean Medical Association 60:3, pages 251.
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Jong Soo LeeJong Moon ParkHyun Kyung ChoSu Jin KimHyoun Do HuhYoung Min Park. (2017) Ocular Side Effects Induced by 0.25% Alcaftadine Ophthalmic Solution. Journal of the Korean Ophthalmological Society 58:5, pages 595.
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Michael H. Goldstein, Karen L. Tubridy, Jennifer Agahigian, Eric Furfine, Marianne Magill, Joseph Kovalchin, Kathryn Golden, Gregory Zarbis-Papastoitsis, Fiona Soong, Anne Marie Salapatek, Gary Sternberg & Abbie Celniker. (2015) A Phase 2 Exploratory Study of a Novel Interleukin-1 Receptor Inhibitor (EBI-005) in the Treatment of Moderate-to-Severe Allergic Conjunctivitis. Eye & Contact Lens: Science & Clinical Practice 41:3, pages 145-155.
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Robin L. Thurmond, Kayvan Kazerouni, Sandra R. Chaplan & Andrew J. Greenspan. 2015. Pharmacology of Itch. Pharmacology of Itch 257 290 .
Hiroshi Fujishima, Yuichi Ohashi & Etsuko Takamura. (2014) Efficacy of epinastine hydrochloride ophthalmic solution in allergic conjunctivitis by conjunctival cedar pollen allergen challenge. Annals of Allergy, Asthma & Immunology 113:4, pages 476-481.
Crossref
Eugene B. McLaurin, Nicholas P. Marsico, Stacey L. Ackerman, Joseph B. Ciolino, Julia M. Williams, Linda Villanueva & David A. Hollander. (2014) Ocular Itch Relief with Alcaftadine 0.25% Versus Olopatadine 0.2% in Allergic Conjunctivitis: Pooled Analysis of Two Multicenter Randomized Clinical Trials. Advances in Therapy 31:10, pages 1059-1071.
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E Carstens & Tasuku AkiyamaRobin Thurmond, Kayvan Kazerouni, Sandra Chaplan & Andrew Greenspan. 2014. Itch. Itch 143 192 .
Garry M. Walsh. 2014. A worldwide yearly survey of new data in adverse drug reactions and interactions. A worldwide yearly survey of new data in adverse drug reactions and interactions 295 307 .
F. Estelle R. Simons & Cezmi A. Akdis. 2014. Middleton's Allergy. Middleton's Allergy 1503 1533 .
Andrea Leonardi & Neal P. Barney. 2014. Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders. Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders 1 18 .
Terrence P. O’Brien. (2013) Allergic conjunctivitis. Current Opinion in Allergy & Clinical Immunology 13:5, pages 543-549.
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Amy T. Kelmenson, Naveen K. Rao & Michael B. Raizman. 2013. Ocular Surface Disease: Cornea, Conjunctiva and Tear Film. Ocular Surface Disease: Cornea, Conjunctiva and Tear Film 117 124 .
Laurie Wade, Leonard Bielory & Shara Rudner. (2012) Ophthalmic antihistamines and H1–H4 receptors. Current Opinion in Allergy & Clinical Immunology 12:5, pages 510-516.
Crossref
Tracy D Mahvan, Whitney A Buckley & Jaime R Hornecker. (2012) Alcaftadine for the Prevention of Itching Associated with Allergic Conjunctivitis. Annals of Pharmacotherapy 46:7-8, pages 1025-1032.
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Osmo Kari & K. Matti Saari. (2012) Diagnostics and New Developments in the Treatment of Ocular Allergies. Current Allergy and Asthma Reports 12:3, pages 232-239.
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Mark B. Abelson, James T. McLaughlin & Paul J. Gomes. (2011) Antihistamines in Ocular Allergy: Are They All Created Equal?. Current Allergy and Asthma Reports 11:3, pages 205-211.
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Joanne Bronson, Murali Dhar, William Ewing & Nils Lonberg. 2011. 433 502 .

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