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Original Article

Darbepoetin alfa for anemia in patients with low or intermediate-1 risk myelodysplastic syndromes and positive predictive factors of response

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Pages 951-960 | Accepted 07 Feb 2011, Published online: 07 Mar 2011

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Read on this site (3)

Jonathan Feld, Abigail Belasen & Shyamala C Navada. (2020) Myelodysplastic syndromes: a review of therapeutic progress over the past 10 years. Expert Review of Anticancer Therapy 20:6, pages 465-482.
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Roberto Castelli, Luigi Bergamaschini, Riccardo Schiavon & Giorgio Lambertenghi-Deliliers. (2017) Personalized treatment strategies for elderly patients with myelodysplastic syndromes. Expert Review of Hematology 10:12, pages 1077-1086.
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David J Seastone & Aaron T Gerds. (2015) Darbepoetin alfa for anemia with myelodysplastic syndrome. Expert Review of Hematology 8:2, pages 139-146.
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Articles from other publishers (24)

Allison Mo, Matthew Poynton, Erica Wood, Jake Shortt, Susan J. Brunskill, Carolyn Doree, Josie Sandercock, Nicholas Saadah, Edwin Luk, Simon J. Stanworth & Zoe McQuilten. (2023) Do anemia treatments improve quality of life and physical function in patients with myelodysplastic syndromes (MDS)? A systematic review. Blood Reviews 61, pages 101114.
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Muzeyyen Aslaner Ak, Birsen Sahip, Ayfer Geduk, Mehmer Ali Ucar, Hacer Kale, Tugba Hacibekiroglu, Merve Gokcen Polat, Yasin Kalpakci, Ali Zahit Bolaman, Birol Guvenc & Sehmus Ertop. (2021) The Clinical Efficacy of Epoetin Alfa and Darbepoetin Alfa in Patients with Low-Risk or Intermediate-1-Risk Myelodysplastic Syndrome: Retrospective Multi-center Real-Life Study. Indian Journal of Hematology and Blood Transfusion 38:2, pages 299-308.
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Esther Natalie Oliva, Uwe Platzbecker, Guillermo Garcia-Manero, Ghulam J. Mufti, Valeria Santini, Mikkael A. Sekeres, Rami S. Komrokji, Jeevan K. Shetty, Derek Tang, Shien Guo, Weiqin Liao, George Zhang, Xianwei Ha, Rodrigo Ito, Jennifer Lord-Bessen, Jay T. Backstrom & Pierre Fenaux. (2021) Health-Related Quality of Life Outcomes in Patients with Myelodysplastic Syndromes with Ring Sideroblasts Treated with Luspatercept in the MEDALIST Phase 3 Trial. Journal of Clinical Medicine 11:1, pages 27.
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Esther N. Oliva, Uwe Platzbecker, Pierre Fenaux, Guillermo Garcia-Manero, Thomas W. LeBlanc, Bhumika J. Patel, Anne Sophie Kubasch & Mikkael A. Sekeres. (2021) Targeting health-related quality of life in patients with myelodysplastic syndromes – Current knowledge and lessons to be learned. Blood Reviews 50, pages 100851.
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Karen-Sue B. Carlson, Joshua Morris, Lauryn P. Cross & Sridhar Rao. 2020. Contemporary Bone Marrow Transplantation. Contemporary Bone Marrow Transplantation 1 14 .
Karen-Sue B. Carlson, Joshua Morris, Lauryn P. Cross & Sridhar Rao. 2021. Contemporary Bone Marrow Transplantation. Contemporary Bone Marrow Transplantation 29 42 .
Sophie Park, Charikleia Kelaidi, Mathieu Meunier, Nicole Casadevall, Aaron T. Gerds & Uwe Platzbecker. (2019) The prognostic value of serum erythropoietin in patients with lower-risk myelodysplastic syndromes: a review of the literature and expert opinion. Annals of Hematology 99:1, pages 7-19.
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Uma Borate, Brianna A. NorrisAbby Statler, Rongwei Fu, Taylor BucyMikkael A. Sekeres. (2019) Representation of therapy-related myelodysplastic syndrome in clinical trials over the past 20 years. Blood Advances 3:18, pages 2738-2747.
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Pere Gascón, Andriy Krendyukov, Nicola Mathieson & Matti Aapro. (2019) Epoetin alfa for the treatment of myelodysplastic syndrome-related anemia: A review of clinical data, clinical guidelines, and treatment protocols. Leukemia Research 81, pages 35-42.
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Lucas Affentranger, Julia Bohlius, Mahmoud Hallal & Nicolas Bonadies. (2019) Efficacy of granulocyte colony stimulating factor in combination with erythropoiesis stimulating agents for treatment of anemia in patients with lower risk myelodysplastic syndromes: A systematic review. Critical Reviews in Oncology/Hematology 136, pages 37-47.
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Sophie Park, Peter Greenberg, Aylin Yucel, Caroline Farmer, Frank O'Neill, Cisio De Oliveira Brandao & Pierre Fenaux. (2018) Clinical effectiveness and safety of erythropoietin‐stimulating agents for the treatment of low‐ and intermediate‐1−risk myelodysplastic syndrome: a systematic literature review. British Journal of Haematology 184:2, pages 134-160.
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Roberto Castelli, Riccardo Schiavon & Giorgio Lambertenghi Deliliers. (2018) The impact of anaemia, transfusion dependency, comorbidities and polypharmacy in elderly patients with low-risk myelodysplastic syndromes. Medical Oncology 35:3.
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S. Park & K. Götze. 2018. Myelodysplastic Syndromes. Myelodysplastic Syndromes 83 95 .
U Platzbecker, A Symeonidis, E N Oliva, J S Goede, M Delforge, J Mayer, B Slama, S Badre, E Gasal, B Mehta & J Franklin. (2017) A phase 3 randomized placebo-controlled trial of darbepoetin alfa in patients with anemia and lower-risk myelodysplastic syndromes. Leukemia 31:9, pages 1944-1950.
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Antonio Gidaro, Giorgio Lambertenghi Deliliers, Paolo Gallipoli, Massimo Arquati, Maddalena Alessandra Wu & Roberto Castelli. (2016) Laboratory and clinical risk assessment to treat myelodysplatic syndromes. Clinical Chemistry and Laboratory Medicine (CCLM) 54:9, pages 1411-1426.
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Sophie Park, Pierre Fenaux, Peter Greenberg, Bhakti Mehta, Fiona Callaghan, Christopher Kim, Dianne Tomita & Hairong Xu. (2016) Efficacy and safety of darbepoetin alpha in patients with myelodysplastic syndromes: a systematic review and meta‐analysis. British Journal of Haematology 174:5, pages 730-747.
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Jun Ho Jang, Hironori Harada, Hirohiko Shibayama, Ryutaro Shimazaki, Hyeoung-Joon Kim, Kenichi Sawada & Kinuko Mitani. (2015) A randomized controlled trial comparing darbepoetin alfa doses in red blood cell transfusion-dependent patients with low- or intermediate-1 risk myelodysplastic syndromes. International Journal of Hematology 102:4, pages 401-412.
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Nataša Debeljak, Peter Solár & Arthur J. Sytkowski. (2014) Erythropoietin and Cancer: The Unintended Consequences of Anemia Correction. Frontiers in Immunology 5.
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Roberto Castelli, Giorgio Lambertenghi Deliliers, Riccardo Colombo, Guido Moreo, Paolo Gallipoli & Giuseppe Pantaleo. (2014) Biosimilar epoetin in elderly patients with low-risk myelodysplastic syndromes improves anemia, quality of life, and brain function. Annals of Hematology 93:9, pages 1523-1529.
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Luca MalcovatiEva Hellström-LindbergDavid BowenLionel AdèsJaroslav CermakConsuelo del CañizoMatteo G. Della Porta, Pierre FenauxNorbert GattermannUlrich GermingJoop H. JansenMoshe MittelmanGhulam MuftiUwe PlatzbeckerGuillermo F. SanzDominik SelleslagMette Skov-HolmReinhard StauderArgiris Symeonidis, Arjan A. van de Loosdrecht, Theo de WitteMario Cazzola. (2013) Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet. Blood 122:17, pages 2943-2964.
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C. Kelaidi, O. Beyne-Rauzy, T. Braun, R. Sapena, P. Cougoul, L. Adès, F. Pillard, C. Lambert, J. C. Charniot, A. Guerci, B. Choufi, A. Stamatoullas, B. Slama, B. De Renzis, S. Ame, G. Damaj, F. Boyer, M. P. Chaury, L. Legros, S. Cheze, A. Testu, E. Gyan, M. C. Béné, C. Rose, F. Dreyfus & P. Fenaux. (2013) High response rate and improved exercise capacity and quality of life with a new regimen of darbepoetin alfa with or without filgrastim in lower-risk myelodysplastic syndromes: a phase II study by the GFM. Annals of Hematology 92:5, pages 621-631.
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Valeria Santini. (2012) Treatment of Low-Risk Myelodysplastic Syndrome: Hematopoietic Growth Factors Erythropoietins and Thrombopoietins. Seminars in Hematology 49:4, pages 295-303.
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Elena Crisà, Cristina Foli, Roberto Passera, Antonella Darbesio, Kimberly B. Garvey, Mario Boccadoro & Dario Ferrero. (2012) Long‐term follow‐up of myelodysplastic syndrome patients with moderate/severe anaemia receiving human recombinant erythropoietin + 13‐ cis ‐retinoic acid and dihydroxylated vitamin D 3: independent positive impact of erythroid response on survival . British Journal of Haematology 158:1, pages 99-107.
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Mary Laudon Thomas, Nicole Crisp & Karen Campbell. (2012) The Importance of Quality of Life for Patients Living With Myelodysplastic Syndromes. Clinical Journal of Oncology Nursing 16:0, pages 47-57.
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