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Research Articles

Impact of low-grade adverse events on health-related quality of life in adult patients receiving imatinib or nilotinib for newly diagnosed Philadelphia chromosome positive chronic myelogenous leukemia in chronic phase

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Pages 2317-2328 | Accepted 10 Jul 2014, Published online: 05 Aug 2014

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Fabio Efficace, Alessandra Iurlo, Andrea Patriarca, Fabio Stagno, Ping-Chong Bee, Geneviève Ector, Isabella Capodanno, Chiara Elena, Massimiliano Bonifacio, Nicole M. A. Blijlevens, Giovanni Caocci, Chonghua Wan, Elisabetta Abruzzese, Massimo Breccia, Francesco Cottone, Iris Okumura, Simone Oerlemans, Nicola Cascavilla, Francesco Albano, Vamsi Kota, Monika Sztankay, Maria Cristina Miggiano, Susanne Saussele, Nicola Di Renzo, Federica Sorà, Fausto Castagnetti, Michele Baccarani, Marco Vignetti & Gianantonio Rosti. (2021) Validation and reference values of the EORTC QLQ-CML24 questionnaire to assess health-related quality of life in patients with chronic myeloid leukemia. Leukemia & Lymphoma 62:3, pages 669-678.
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Nana Brochmann, Esben Meulengracht Flachs, Anne Illemann Christensen, Christen Lykkegaard Andersen, Knud Juel, Hans Carl Hasselbalch & Ann-Dorthe Zwisler. (2017) A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents. Clinical Epidemiology 9, pages 141-150.
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Federico De Marchi, Marta Medeot, Renato Fanin & Mario Tiribelli. (2017) How could patient reported outcomes improve patient management in chronic myeloid leukemia?. Expert Review of Hematology 10:1, pages 9-14.
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Lauren Caldemeyer & Luke P. Akard. (2016) Rationale and motivating factors for treatment-free remission in chronic myeloid leukemia. Leukemia & Lymphoma 57:12, pages 2739-2751.
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Massimo Breccia, Gioia Colafigli, Matteo Molica & Giuliana Alimena. (2016) Adverse events associated with tyrosine kinase inhibitors for the treatment of chronic myeloid leukemia. Expert Opinion on Drug Safety 15:4, pages 525-533.
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Benedito A Carneiro, Jason B Kaplan & Francis J Giles. (2015) Tyrosine kinase inhibitor therapy in chronic myeloid leukemia: update on key adverse events. Expert Review of Hematology 8:4, pages 457-479.
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Ann Hewison, Eve Roman, Alexandra Smith, Dorothy McCaughan, Rebecca Sheridan, Russell Patmore, Karl Atkin & Debra Howell. (2023) Chronic Myeloid Leukaemia: A Qualitative Study of Patient and Practitioner Experiences of Managing Treatment. European Journal of Cancer Care 2023, pages 1-12.
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Gianantonio Rosti, Tim H. Brümmendorf, Björn T. Gjertsen, Pilar Giraldo-Castellano, Fausto Castagnetti, Carlo Gambacorti-Passerini, Thomas Ernst, Huadong Zhao, Luke Kuttschreuter, Simon Purcell, Francis J. Giles & Andreas Hochhaus. (2023) Impact of age and comorbidities on the efficacy and tolerability of bosutinib in previously treated patients with chronic myeloid leukemia: results from the phase 4 BYOND study. Leukemia.
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Yolba Smit, Sanne J J P M Metsemakers, Jeroen J W M Janssen, Eduardus F M Posthuma, Iris Walraven, Rosella P M G Hermens & Nicole M A Blijlevens. (2023) Measuring chronic myeloid leukaemia TKI-related toxic effects in the real world: a systematic review and critical assessment of content validity of patient-reported outcome measures. The Lancet Haematology.
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Yilin Chen, Na Xu, Yunfan Yang, Zhenfang Liu, Mengxing Xue, Li Meng, Qun He, Chunyan Chen, Qingshu Zeng, Huanling Zhu, Xin Du, Jing Zou, Wenjun He, Jingming Guo, Suning Chen, Guolin Yuan, Hui Wu, Mei Hong, Fanjun Cheng, Bingcheng Liu, Yanli Zhang & Weiming Li. (2023) Quality‐of‐life, mental health, and perspective on TKI dose reduction as a prelude to discontinuation in chronic phase chronic myeloid leukemia . Cancer Medicine 12:16, pages 17239-17252.
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Paola Pacelli, Adele Santoni, Anna Sicuranza, Elisabetta Abruzzese, Valentina Giai, Monica Crugnola, Mario Annunziata, Sara Galimberti, Alessandra Iurlo, Luigiana Luciano, Federica Sorà, Carmen Fava, Elena Bestoso, Cristina Marzano, Alessandra Cartocci, Marzia Defina, Vincenzo Sammartano, Emanuele Cencini, Donatella Raspadori & Monica Bocchia. (2023) Prospective monitoring of chronic myeloid leukemia patients from the time of TKI discontinuation: the fate of peripheral blood CD26+ leukemia stem cells. Frontiers in Pharmacology 14.
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Melissa F Djodikromo, Rosella PMG Hermens, Bart JF van den Bemt, Yolba Smit, Tim M Govers, Charlotte L Bekker & Nicole MA Blijlevens. (2023) Patient-guided dose reduction of tyrosine kinase inhibitors in chronic myeloid leukaemia (RODEO study): study protocol for a prospective, multicentre, single-arm trial. BMC Cancer 23:1.
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Antonio E. Nardi, Federica Sancassiani, Vanessa Barrui, Goce Kalcev, Veronica Uras, Giulia Meloni, Luigi Marongiu, Giorgio Tamburini, Alberto Maleci, Laiana A. Quagliato, Giorgio La Nasa & Mauro Giovanni Carta. (2023) The Effects of Tyrosine Kinase Inhibitors (TKIs) in Monotherapy and with Add-on Treatments on Health-related Quality of Life of People with Chronic Myeloid Leukemia: A Systematic Review of Randomized-Controlled Trials. Clinical Practice & Epidemiology in Mental Health 19:1.
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Kelly L. Schoenbeck & Kathryn E. Flynn. (2021) Health-Related Quality of Life of Patients with Chronic Myeloid Leukemia as Measured by Patient-Reported Outcomes: Current State and Future Directions. Current Hematologic Malignancy Reports 16:6, pages 491-499.
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Sharifa Ezat Wan Puteh, Azimatun Noor Aizuddin, Nor Rafeah Tumian, Jameela Sathar & Ellyana Mohamad Selamat. (2021) Health-related quality of life using EQ-5D among chronic myeloid leukaemia patients in health centres in Klang Valley, Malaysia. PLOS ONE 16:8, pages e0256804.
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Hilbeen Hisham Saifullah & Claire Marie Lucas. (2021) Treatment-Free Remission in Chronic Myeloid Leukemia: Can We Identify Prognostic Factors?. Cancers 13:16, pages 4175.
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Samantha C. Sodergren, Sally J. Wheelwright, Deborah Fitzsimmons, Fabio Efficace, Mirjam Sprangers, Peter Fayers, Amelie Harle, Heike Schmidt, Andrew Bottomley, Anne-Sophie Darlington, Charlotte Benson, Anne Bredart, Leopold Hentschel, Juan Ignacio Arraras, Georgios Ioannidis, Michael Leahy, Iwona Lugowska, Ourania Nicolatou-Galitis, Duska Petranovic, Gudrun E Rohde, Vasilis Vassiliou & Colin D. Johnson. (2020) Developing Symptom Lists for People with Cancer Treated with Targeted Therapies. Targeted Oncology 16:1, pages 95-107.
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Ruth Stuckey, Juan Francisco López-Rodríguez, Santiago Sánchez-Sosa, Adrián Segura-Díaz, Nuria Sánchez-Farías, Cristina Bilbao-Sieyro & María Teresa Gómez-Casares. (2020) Predictive indicators of successful tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia. World Journal of Clinical Oncology 11:12, pages 996-1007.
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Christel C. L. M. Boons, Lonneke Timmers, Jeroen J. W. M. Janssen, Peter E. Westerweel, Nicole M. A. Blijlevens, Willem M. Smit, Imke H. Bartelink, Janneke A. Wilschut, Eleonora L. Swart, N. Harry Hendrikse & Jacqueline G. Hugtenburg. (2020) Response and Adherence to Nilotinib in Daily practice (RAND study): an in-depth observational study of chronic myeloid leukemia patients treated with nilotinib. European Journal of Clinical Pharmacology 76:9, pages 1213-1226.
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Jeff P. Sharman, Kim Cocks, Chadi Nabhan, Nicole Lamanna, Neil E. Kay, David L. Grinblatt, Christopher R. Flowers, Matthew S. Davids, Pavel Kiselev, Arlene S. Swern, Kristen Sullivan, Mecide M. Gharibo, E. Dawn Flick, Andrew Trigg & Anthony Mato. (2020) Longitudinal health‐related quality of life in first‐line treated patients with chronic lymphocytic leukemia: Results from the Connect ® CLL Registry . eJHaem 1:1, pages 188-198.
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Tim H. Brümmendorf, Carlo Gambacorti-Passerini, Andrew G. Bushmakin, Joseph C. Cappelleri, Andrea Viqueira, Arlene Reisman, Susanne Isfort & Carla Mamolo. (2020) Relationship between molecular response and quality of life with bosutinib or imatinib for chronic myeloid leukemia. Annals of Hematology 99:6, pages 1241-1249.
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Hélène Haguet, Carlos Graux, François Mullier, Jean-Michel Dogné & Jonathan Douxfils. (2020) Long-Term Survival, Vascular Occlusive Events and Efficacy Biomarkers of First-Line Treatment of CML: A Meta-Analysis. Cancers 12:5, pages 1242.
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Lu Yu, Xiaojun Huang, Robert Peter Gale, Haibo Wang & Qian Jiang. (2019) Variables associated with patient-reported symptoms in persons with chronic phase chronic myeloid leukemia receiving tyrosine kinase inhibitor therapy. Medicine 98:48, pages e18079.
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Lu Yu, Haibo Wang, Darko Milijkovic, Xiaojun Huang & Qian Jiang. (2018) Achieving optimal response at 12 months is associated with a better health-related quality of life in patients with chronic myeloid leukemia: a prospective, longitudinal, single center study. BMC Cancer 18:1.
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Ami B. Patel, Thoralf Lange, Anthony D. Pomicter, Christopher J. Conley, Christina A. Harrington, Kimberly R. Reynolds, Todd W. Kelley, Thomas O’Hare & Michael W. Deininger. (2018) Similar expression profiles in CD34+ cells from chronic phase chronic myeloid leukemia patients with and without deep molecular responses to nilotinib. Oncotarget 9:25, pages 17889-17894.
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Devendra Hiwase, Peter Tan, James D’Rozario, John Taper, Anthony Powell, Ian Irving, Matthew Wright, Susan Branford, David T. Yeung, Luke Anderson, Othon Gervasio, Carly Levetan, Will Roberts, Ann Solterbeck, Robert Traficante & Timothy Hughes. (2018) Efficacy and safety of nilotinib 300 mg twice daily in patients with chronic myeloid leukemia in chronic phase who are intolerant to prior tyrosine kinase inhibitors: Results from the Phase IIIb ENESTswift study. Leukemia Research 67, pages 109-115.
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Qian Jiang, Haibo Wang, Lu Yu & Robert Peter Gale. (2017) Higher out-of-pocket expenses for tyrosine kinase-inhibitor therapy is associated with worse health-related quality-of-life in persons with chronic myeloid leukemia. Journal of Cancer Research and Clinical Oncology 143:12, pages 2619-2630.
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Ravi Kishore Narra, Kathryn E. Flynn & Ehab Atallah. (2017) Chronic Myeloid Leukemia—the Promise of Tyrosine Kinase Inhibitor Discontinuation. Current Hematologic Malignancy Reports 12:5, pages 415-423.
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Qian Jiang, Hai-Bo Wang, Lu Yu & Robert Peter Gale. (2017) Variables associated with patient-reported outcomes in persons with chronic myeloid leukemia receiving tyrosine kinase-inhibitor therapy. Journal of Cancer Research and Clinical Oncology 143:6, pages 1013-1022.
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Fabio Efficace & Laura Cannella. (2016) The value of quality of life assessment in chronic myeloid leukemia patients receiving tyrosine kinase inhibitors. Hematology 2016:1, pages 170-179.
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Fabio Efficace, Massimo Breccia, Francesco Cottone, Iris Okumura, Maribel Doro, Francesca Riccardi, Gianantonio Rosti & Michele Baccarani. (2016) Psychological well-being and social support in chronic myeloid leukemia patients receiving lifelong targeted therapies. Supportive Care in Cancer 24:12, pages 4887-4894.
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Stéphanie Dulucq & Francois‐Xavier Mahon. (2016) Deep molecular responses for treatment‐free remission in chronic myeloid leukemia. Cancer Medicine 5:9, pages 2398-2411.
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Kendra Sweet & Javier Pinilla-Ibarz. (2016) Early switch in tyrosine kinase inhibitor therapy for patients with chronic myeloid leukemia: An emerging clinical question. Critical Reviews in Oncology/Hematology 103, pages 99-108.
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