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Effect of nefopam- versus fentanyl-based patient-controlled analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective double-blind randomized controlled trial

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Pages 1599-1607 | Accepted 26 May 2015, Published online: 06 Jul 2015

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Jie Luo & Su Min. (2017) Postoperative pain management in the postanesthesia care unit: an update. Journal of Pain Research 10, pages 2687-2698.
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Maksym Shostak & Oleksii Domoratskyi. (2023) The use of centrally acting analgesics in the postoperative analgesia in patients with the consequences of a severe mine-explosive injury of the lower extremities. Perioperaciina Medicina 5:2, pages 27-31.
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M.A. Shostak, V.V. Kryzhevskyi, O.E. Domoratskyi, V.Yu. Hladkykh & O.A. Yakubets. (2022) Перспектива застосування сучасних анальгетиків центральної дії для лікування гострого післяопераційного болю в пацієнтів травматологічного профілю. EMERGENCY MEDICINE 18:2, pages 87-90.
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Ki Tae Jung, Keum Young So, Seung Chul Kim & Sang Hun Kim. (2021) Effect of Nefopam-Based Patient-Controlled Analgesia with and without Fentanyl on Postoperative Pain Intensity in Patients Following Laparoscopic Cholecystectomy: A Prospective, Randomized, Controlled, Double-Blind Non-Inferiority Trial. Medicina 57:4, pages 316.
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Soomin Lee, Seounghun Lee, Hoseop Kim, Chahyun Oh, Sooyong Park, Yeojung Kim, Boohwi Hong, Seokhwa Yoon, Chan Noh & Youngkwon Ko. (2021) The Analgesic Efficacy of Nefopam in Patient-Controlled Analgesia after Laparoscopic Gynecologic Surgery: A Randomized, Double-Blind, Non-Inferiority Study. Journal of Clinical Medicine 10:5, pages 1043.
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Varinee Lekprasert, Lapuskorn Yapanan, Wichai Ittichaikulthol, Rungrawan Buachai, Phimol Soisod & Areepan Sophonsritsuk. (2021) Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind Study. Anesthesiology Research and Practice 2021, pages 1-7.
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Sun-Kyung Park, Hansol Kim, Seokha Yoo, Won Ho Kim, Young-Jin Lim & Jin-Tae Kim. (2021) Predicted Versus Non-Predicted Opioid Administration Using Preoperative Pain Sensitivity in Patients Undergoing Gynecological Surgery: A Randomized-Controlled Trial. Journal of Clinical Medicine 10:4, pages 585.
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YoonJu Go, Jun-Young Chung, Jae-woo Yi, Bong-Jae Lee & Hyungseok Seo. (2021) The effect of using nefopam in fentanyl-based intravenous patient-controlled analgesia on the incidence of postoperative nausea and vomiting in laparoscopic gynecological surgery. Medical Biological Science and Engineering 4:1, pages 20-26.
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Elise D'Huart, Jean Vigneron, Igor Clarot & Béatrice Demoré. (2020) Physicochemical stability of nefopam and nefopam/droperidol solutions in polypropylene syringes for intensive care units. European Journal of Hospital Pharmacy 27:e1, pages e69-e73.
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Michael Conrad Grant, Melinda M Gibbons, Clifford Y Ko, Elizabeth C Wick, Maxime Cannesson, Michael J Scott & Christopher L Wu. (2019) Evidence review conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery: focus on anesthesiology for gynecologic surgery. Regional Anesthesia & Pain Medicine 44:4, pages 437-446.
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Eunhye Choi, Myong-Hwan Karm, Eunsun So, Yoon Ji Choi, Sookyung Park, Yul Oh, Hye Joo Yun, Hyun Jeong Kim & Kwang-Suk Seo. (2019) Effects on postoperative nausea and vomiting of nefopam versus fentanyl following bimaxillary orthognathic surgery: a prospective double-blind randomized controlled trial. Journal of Dental Anesthesia and Pain Medicine 19:1, pages 55.
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Heezoo Kim, Dong Kyu Lee, Mi Kyoung Lee & Mido Lee. (2018) Median effective dose of nefopam to treat postoperative pain in patients who have undergone laparoscopic cholecystectomy. Journal of International Medical Research 46:9, pages 3684-3691.
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Sun-Kyung Park, Seokha Yoo, Won Ho Kim, Young-Jin Lim, Jae-Hyon Bahk & Jin-Tae Kim. (2018) Association of nefopam use with postoperative nausea and vomiting in gynecological patients receiving prophylactic ramosetron: A retrospective study. PLOS ONE 13:6, pages e0199930.
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Hyun Seung Jin, Yong Chul Kim, Yongjae Yoo, Changsoon Lee, Chan Woo Cho & Won-joong Kim. (2016) Opioid sparing effect and safety of nefopam in patient controlled analgesia after laparotomy: A randomized, double blind study. Journal of International Medical Research 44:4, pages 844-854.
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