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Current Medical Research and Opinion Volume 1, 1973 - Issue 8
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Research Article

A clinical trial comparing 'Hydergine' with placebo in the treatment of cerebrovascular insufficiency in elderly patients

R. W. McConnachie Department of Geriatric Medicine, Royal Hospital, Chesterfield, England
, M.B., Ch.B., M.R.C.P., D.P.H., D.I.H.
Pages 463-468 | Received 31 May 1973, Published online: 04 Aug 2008

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A. Arrigo, R. Casale, I. Giorgi, C. Guarnaschelli & F. Zelaschi. (1989) Effects of Intravenous High Dose Co-Dergocrine Mesylate (‘Hydergine’®) in Elderly Patients with Severe Multi-Infarct Dementia: a Double-Blind, Placebo-Controlled Trial. Current Medical Research and Opinion 11:8, pages 491-500.
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C. G. Elliott, Alan L. Brown & T. C. G. Smith. (1973) Multi-centre general practitioner trial of isoxsuprine in cerebrovascular disease: a pilot study. Current Medical Research and Opinion 1:9, pages 554-562.
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Articles from other publishers (17)

Lon Schneider, Jason T Olin, Adrian Novit & Susan Luczak. (2000) Hydergine for dementia. Cochrane Database of Systematic Reviews.
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H. Herrschaft. 1999. Neuro-Psychopharmaka Ein Therapie-Handbuch. Neuro-Psychopharmaka Ein Therapie-Handbuch 581 595 .
Ronald Ammon, Rehka Sharma, Steven R. Gambert & Krishan Lal Gupta. (1995) Hydergine revisited: A statistical analysis of studies showing efficacy in the treatment of cognitively impaired elderly. AGE 18:1, pages 5-9.
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Jair C. Soares & Samuel Gershon. (1994) Advances in the pharmacotherapy of Alzheimer's disease. European Archives of Psychiatry and Clinical Neuroscience 244:5, pages 261-271.
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J. Kleijnen & P. Knipschild. (2012) Ginkgo biloba for cerebral insufficiency.. British Journal of Clinical Pharmacology 34:4, pages 352-358.
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Bernd Saletu, Josef Grünberger, Leopold Linzmayer & Peter Anderer. (1992) Dose-response studies with co-dergocrine mesylate under hypoxia utilizing EEG mapping and psychometry. Psychopharmacology 109:1-2, pages 30-40.
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H. Herrschaft. 1992. Neuro-Psychopharmaka. Neuro-Psychopharmaka 225 238 .
Michael A. Jenike, Marilyn Albert, Lee Baer, Jeanette Gunther & Christine Corvino. (2004) Ergot mesylates for alzheimer's disease: A year‐long double‐blind trial of 3 mg vs 12 mg daily. International Journal of Geriatric Psychiatry 5:6, pages 375-380.
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J. M. S. Pearce, M. G. Wallace & R. Capildeo. 1988. Methods in Clinical Trials in Neurology. Methods in Clinical Trials in Neurology 265 294 .
E. Lehmann. 1985. Hirnorganische Psychosyndrome im Alter II. Hirnorganische Psychosyndrome im Alter II 251 259 .
Jack M. Singer, Herman B. Hamot & John R. Patin. 1985. Aging 2000: Our Health Care Destiny. Aging 2000: Our Health Care Destiny 405 420 .
S. Chierichetti, D. Cucinotta & V. Santini. 1985. Aging 2000: Our Health Care Destiny. Aging 2000: Our Health Care Destiny 377 393 .
E. Lehmann, K. Heinrich, H. Quadbeck & J. Tegeler. 1984. Forschungen zur Biologischen Psychiatrie. Forschungen zur Biologischen Psychiatrie 85 92 .
I. HINDMARCH, A. C. PARROTT & M. LANZA. (2013) The Effects of an Ergot Alkaloid Derivative (Hydergine) on Aspects of Psychomotor Performance, Arousal, and Cognitive Processing Ability. The Journal of Clinical Pharmacology 19:11, pages 726-732.
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R. D. Venn. 1978. Ergot Alkaloids and Related Compounds. Ergot Alkaloids and Related Compounds 533 566 .
H. Hauth & B.P. Richardson. 1977. 49 59 .
JOHN R. HUGHES, JAMES G. WILLIAMS & ROBERT D. CURRIER. (2015) An Ergot Alkaloid Preparation (Hydergine) in the Treatment of Dementia: Critical Review of the Clinical Literature. Journal of the American Geriatrics Society 24:11, pages 490-497.
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