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Research Article

St John's Wort (‘Hypericum perforatum’) - a Herbal Antidepressant

Pages 171-184 | Accepted 20 May 1998, Published online: 26 Aug 2008

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Kalyan Immadisetty, Laura M Geffert, Christopher K Surratt & Jeffry D Madura. (2013) New design strategies for antidepressant drugs. Expert Opinion on Drug Discovery 8:11, pages 1399-1414.
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Michiel E. H. Hemels, Colin Vicente, Hamid Sadri, Mary Jane Masson & Thomas R. Einarson. (2004) Quality assessment of meta-analyses of RCTs of pharmacotherapy in major depressive disorder. Current Medical Research and Opinion 20:4, pages 477-484.
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Elizabeta Dimitrieska‐Stojković & Zoran Zdravkovski. (2003) Supercritical Fluid Extraction of Quercetin and Rutin from Hyperici Herba. Journal of Liquid Chromatography & Related Technologies 26:15, pages 2517-2533.
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Articles from other publishers (16)

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Vahid MehrnoushFatemeh Darsareh, Nasibeh RoozbehAvan Ziraeie. (2021) Efficacy of the Complementary and Alternative Therapies for the Management of Psychological Symptoms of Menopause: A Systematic Review of Randomized Controlled Trials. Journal of Menopausal Medicine 27:3, pages 115.
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Chang-Hua Xu, Ping Wang, Yang Wang, Yan Yang, Dong-Hua Li, Hui-Fen Li, Su-Qin Sun & Xian-Zhong Wu. (2013) Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: Competing mechanisms between paeoniflorin and glycyrrhetinic acid. Journal of Ethnopharmacology 149:2, pages 443-452.
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M Ang-Lee & D Basila. 2011. Traditional Chinese Medicine. Traditional Chinese Medicine 5 31 .
Siegfried Kasper, Markus Gastpar, Hans-Juergen Möller, Walter E. Müller, Hans-Peter Volz, Angelika Dienel & Meinhard Kieser. (2010) Better tolerability of St. Johnʼs wort extract WS 5570 compared to treatment with SSRIs: a reanalysis of data from controlled clinical trials in acute major depression. International Clinical Psychopharmacology 25:4, pages 204-213.
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Karen Pilkington, Anelia Boshnakova & Janet Richardson. (2006) St John's wort for depression: Time for a different perspective?. Complementary Therapies in Medicine 14:4, pages 268-281.
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Jien Wu, Xiao-Fang Cheng, Leslie J. Harrison, Swee-Hock Goh & Keng-Yeow Sim. (2004) A phloroglucinol derivative with a new carbon skeleton from Hypericum perforatum (Guttiferae). Tetrahedron Letters 45:52, pages 9657-9659.
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R.D. Trautmann-Sponsel & Angelika Dienel. (2004) Safety of Hypericum extract in mildly to moderately depressed outpatients. Journal of Affective Disorders 82:2, pages 303-307.
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Ralf Uebelhack, Joerg Gruenwald, Hans-Joachim Graubaum & Regina Busch. (2004) Efficacy and tolerability of Hypericum extract STW 3-VI in patients with moderate depression: A double-blind, randomized, placebo-controlled clinical trial. Advances in Therapy 21:4, pages 265-275.
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E.A Carlini. (2003) Plants and the central nervous system. Pharmacology Biochemistry and Behavior 75:3, pages 501-512.
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P. Clayton. 2003. Performance Functional Foods. Performance Functional Foods 21 37 .
Fúlvio Rieli Mendes, Rita Mattei & Elisaldo Luiz de Araújo Carlini. (2002) Activity of Hypericum brasiliense and Hypericum cordatum on the central nervous system in rodents. Fitoterapia 73:6, pages 462-471.
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Mi-Hyeon Jang, Taeck-Hyun Lee, Min-Chul Shin, Geon-Ho Bahn, Jong-Woo Kim, Dong-Hoon Shin, Ee-Hwa Kim & Chang-Ju Kim. (2002) Protective effect of Hypericum perforatum Linn (St. John's wort) against hydrogen peroxide-induced apoptosis on human neuroblastoma cells. Neuroscience Letters 329:2, pages 177-180.
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Elisabetta Onelli, Alberto Rivetta, Anna Giorgi, Mauro Bignami, Maurizio Cocucci & Giuseppe Patrignani. (2002) Ultrastructural studies on the developing secretory nodules of Hypericum perforatum. Flora - Morphology, Distribution, Functional Ecology of Plants 197:2, pages 92-102.
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Kirsten Behnke, Gert Saaby Jensen, Hans-Joachim Graubaum & Joerg Gruenwald. (2002) Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression. Advances in Therapy 19:1, pages 43-52.
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Geoffry McEnany. (2016) Herbal Psychotropics. Part 1: Focus on St. John's Wort and SAMe. Journal of the American Psychiatric Nurses Association 5:6, pages 192-196.
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