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Research Article

Co-ingestion of carbohydrate and whey protein isolates enhance PGC-1α mRNA expression: a randomised, single blind, cross over study

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Article: 8 | Published online: 01 Apr 2022

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Mette Hansen, Mikkel Oxfeldt, Anne E. Larsen, Lise S. Thomsen, Torben Rokkedal-Lausch, Britt Christensen, Nikolaj Rittig, Frank V. De Paoli, Jens Bangsbo, Niels Ørtenblad & Klavs Madsen. (2020) Supplement with whey protein hydrolysate in contrast to carbohydrate supports mitochondrial adaptations in trained runners. Journal of the International Society of Sports Nutrition 17:1.
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Jeremy McAdam, Kaitlin McGinnis, Rian Ory, Kaelin Young, Andrew D. Frugé, Michael Roberts & JoEllen Sefton. (2018) Estimation of energy balance and training volume during Army Initial Entry Training. Journal of the International Society of Sports Nutrition 15:1.
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Mette Hansen, Jens Bangsbo, Jørgen Jensen, Matilde Krause-Jensen, Bo Martin Bibby, Ove Sollie, Ulrika Andersson Hall & Klavs Madsen. (2016) Protein intake during training sessions has no effect on performance and recovery during a strenuous training camp for elite cyclists. Journal of the International Society of Sports Nutrition 13:1.
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Christopher Brooks Mobley, Carlton D Fox, Brian S Ferguson, Corrie A Pascoe, James C Healy, Jeremy S McAdam, Christopher M Lockwood & Michael D Roberts. (2015) Effects of protein type and composition on postprandial markers of skeletal muscle anabolism, adipose tissue lipolysis, and hypothalamic gene expression. Journal of the International Society of Sports Nutrition 12:1.
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Jason S. Hinkle, Caroline N. Rivera & Roger A. Vaughan. (2022) Branched‐Chain Amino Acids and Mitochondrial Biogenesis: An Overview and Mechanistic Summary. Molecular Nutrition & Food Research 66:20.
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Tsubasa Shibaguchi, Rikuhide Koma, Yhusi Karina Riskawati, Yuzumi Kawai, Takashi Yoneda, Hiroki Aizaki, Claudia Pérez-López, Atsushi Tsuji, Yuya Yamazaki, Keizo Matsui & Kazumi Masuda. (2022) Effect of daily intake of a rice fermented beverage on endurance exercise performance in male college student athletes. The Journal of Physical Fitness and Sports Medicine 11:5, pages 279-294.
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Dejan Reljic, Nilas Zieseniss, Hans J. Herrmann, Markus F. Neurath & Yurdagül Zopf. (2022) Protein Supplementation Does Not Maximize Adaptations to Low-Volume High-Intensity Interval Training in Sedentary, Healthy Adults: A Placebo-Controlled Double-Blind Randomized Study. Nutrients 14:19, pages 3883.
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Felicia A. Hartono, Patrick W. Martin-Arrowsmith, Wouter M. Peeters & Tyler A. Churchward-Venne. (2022) The Effects of Dietary Protein Supplementation on Acute Changes in Muscle Protein Synthesis and Longer-Term Changes in Muscle Mass, Strength, and Aerobic Capacity in Response to Concurrent Resistance and Endurance Exercise in Healthy Adults: A Systematic Review. Sports Medicine 52:6, pages 1295-1328.
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Madison E. Rivera, Caroline N. Rivera & Roger A. Vaughan. (2021) Excess branched-chain amino acids alter myotube metabolism and substrate preference which is worsened by concurrent insulin resistance. Endocrine 76:1, pages 18-28.
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Kim GaffneyAdam LuceroDonia Macartney-CoxsonJane ClaphamPatricia WhitfieldBarry R. PalmerStJohn WakefieldJames FaulknerLee StonerDavid S. Rowlands. (2021) Effects of whey protein on skeletal muscle microvascular and mitochondrial plasticity following 10 weeks of exercise training in men with type 2 diabetes. Applied Physiology, Nutrition, and Metabolism 46:8, pages 915-924.
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Patrick Jendricke, Jan Kohl, Christoph Centner, Albert Gollhofer & Daniel König. (2020) Influence of Specific Collagen Peptides and Concurrent Training on Cardiometabolic Parameters and Performance Indices in Women: A Randomized Controlled Trial. Frontiers in Nutrition 7.
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Sarkis J. Hannaian, Mark N. Orlando, Sidney Abou Sawan, Michael Mazzulla, Daniel W. D. West & Daniel R. Moore. (2020) Protein Timing Does Not Affect Next-Day Recovery of Strength or Power but May Enhance Aerobic Adaptations to Short-Term Variable Intensity Exercise Training in Recreationally Active Males: A Pilot Study. Frontiers in Sports and Active Living 2.
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Abdullah F. Alghannam, Iain Templeman, Joel E. Thomas, Dawid Jedrzejewski, Samuel Griffiths, Joseph Lemon, Thomas Byers, Sue Reeves, Javier T. Gonzalez, Dylan Thompson, James Bilzon, Kostas Tsintzas & James A. Betts. (2020) Effect of carbohydrate–protein supplementation on endurance training adaptations. European Journal of Applied Physiology 120:10, pages 2273-2287.
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Yu-Hsuan Cheng, Li Wei, Wing P. Chan, Chih-Yang Hsu, Shih-Wei Huang, Heng Wang & Yen-Nung Lin. (2020) Effects of protein supplementation on aerobic training-induced gains in cardiopulmonary fitness, muscle mass, and functional performance in chronic stroke: A randomized controlled pilot study. Clinical Nutrition 39:9, pages 2743-2750.
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Mads S. Larsen, Dagmar Clausen, Astrid Ank Jørgensen, Ulla R. Mikkelsen & Mette Hansen. (2019) Presleep Protein Supplementation Does Not Improve Recovery During Consecutive Days of Intense Endurance Training: A Randomized Controlled Trial. International Journal of Sport Nutrition and Exercise Metabolism 29:4, pages 426-434.
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Eduard Isenmann, Franziska Blume, Daniel Bizjak, Vera Hundsdörfer, Sarah Pagano, Sebastian Schibrowski, Werner Simon, Lukas Schmandra & Patrick Diel. (2019) Comparison of Pro-Regenerative Effects of Carbohydrates and Protein Administrated by Shake and Non-Macro-Nutrient Matched Food Items on the Skeletal Muscle after Acute Endurance Exercise. Nutrients 11:4, pages 744.
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Ove Sollie, Per B. Jeppesen, Daniel S. Tangen, Fredrik Jernerén, Birgitte Nellemann, Ditta Valsdottir, Klavs Madsen, Cheryl Turner, Helga Refsum, Bjørn S. Skålhegg, John L. Ivy & Jørgen Jensen. (2018) Protein intake in the early recovery period after exhaustive exercise improves performance the following day. Journal of Applied Physiology 125:6, pages 1731-1742.
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Pim Knuiman, Maria T. E. Hopman, Conor Verbruggen & Marco Mensink. (2018) Protein and the Adaptive Response With Endurance Training: Wishful Thinking or a Competitive Edge?. Frontiers in Physiology 9.
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Brendon P. McDermott, Scott A. Anderson, Lawrence E. Armstrong, Douglas J. Casa, Samuel N. Cheuvront, Larry Cooper, W. Larry Kenney, Francis G. O'Connor & William O Roberts. (2017) National Athletic Trainers' Association Position Statement: Fluid Replacement for the Physically Active. Journal of Athletic Training 52:9, pages 877-895.
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B.N.P. Sah, A.J. McAinch & T. Vasiljevic. (2016) Modulation of bovine whey protein digestion in gastrointestinal tract: A comprehensive review. International Dairy Journal 62, pages 10-18.
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Riki Ogasawara, Satoshi Fujita, Troy A. Hornberger, Yu Kitaoka, Yuhei Makanae, Koichi Nakazato & Ishii Naokata. (2016) The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise. Scientific Reports 6:1.
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Carolina Soares Moura, Pablo Christiano Barboza Lollo, Priscila Neder Morato, Eder Muller Risso & Jaime Amaya-Farfan. (2016) Functional effects of milk bioactive peptides on skeletal muscle of rats. Food Research International 84, pages 18-25.
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Andrew C. Betik, Jay Aguila, Glenn K. McConell, Andrew J. McAinch & Michael L. Mathai. (2016) Tocotrienols and Whey Protein Isolates Substantially Increase Exercise Endurance Capacity in Diet -Induced Obese Male Sprague-Dawley Rats. PLOS ONE 11:4, pages e0152562.
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William J. Smiles, John A. Hawley & Donny M. Camera. (2016) Effects of skeletal muscle energy availability on protein turnover responses to exercise. Journal of Experimental Biology 219:2, pages 214-225.
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Lee M. Margolis & Donato A. Rivas. (2014) Implications of Exercise Training and Distribution of Protein Intake on Molecular Processes Regulating Skeletal Muscle Plasticity. Calcified Tissue International 96:3, pages 211-221.
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Abdullah F Alghannam, Kostas Tsintzas, Dylan Thompson, James Bilzon & James A Betts. (2014) Post-Exercise Protein Trial: Interactions between Diet and Exercise (PEPTIDE): study protocol for randomized controlled trial. Trials 15:1.
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Satoshi Haramizu, Noriyasu Ota, Atsuko Otsuka, Kohjiro Hashizume, Satoshi Sugita, Tadashi Hase, Takatoshi Murase & Akira Shimotoyodome. (2014) Dietary milk fat globule membrane improves endurance capacity in mice. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 307:8, pages R1009-R1017.
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Lee M. Margolis & Stefan M. Pasiakos. (2013) Optimizing Intramuscular Adaptations to Aerobic Exercise: Effects of Carbohydrate Restriction and Protein Supplementation on Mitochondrial Biogenesis. Advances in Nutrition 4:6, pages 657-664.
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