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Research Article

Suppression of exercise-induced neutrophilia and lymphopenia in athletes by cystine/theanine intake: a randomized, double-blind, placebo-controlled trial

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Article: 23 | Published online: 06 May 2022

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A. Juszkiewicz, A. Glapa, P. Basta, E. Petriczko, K. Żołnowski, B. Machaliński, J. Trzeciak, K. Łuczkowska & A. Skarpańska-Stejnborn. (2019) The effect of L-theanine supplementation on the immune system of athletes exposed to strenuous physical exercise. Journal of the International Society of Sports Nutrition 16:1.
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Articles from other publishers (23)

Xing-Yu Zhou, Xin Li, Jun Zhang, Ying Li, Xiao-Min Wu, Yi-Zhen Yang, Xiao-Fei Zhang, Lin-Zi Ma, Yu-Dong Liu, Zhe Wang & Shi-Ling Chen. (2023) Plasma metabolomic characterization of premature ovarian insufficiency. Journal of Ovarian Research 16:1.
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Takashi Tsuchiya & Shigekazu Kurihara. (2021) Cystine and Theanine as Stress-Reducing Amino Acids—Perioperative Use for Early Recovery after Surgical Stress. Nutrients 14:1, pages 129.
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Junya Yoneda, Sachiko Nishikawa & Shigekazu Kurihara. (2021) Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model. BMC Cancer 21:1.
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Yi Chung, Yi-Ting Hsiao & Wen-Ching Huang. (2021) Physiological and Psychological Effects of Treadmill Overtraining Implementation. Biology 10:6, pages 515.
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Christoph C. Kaufmann, Claudia Wegberger, Maximilian Tscharre, Paul M. Haller, Edita Piackova, Irena Vujasin, Mona Kassem, Ioannis Tentzeris, Matthias K. Freynhofer, Bernhard Jäger, Johann Wojta & Kurt Huber. (2020) Effect of marathon and ultra‐marathon on inflammation and iron homeostasis. Scandinavian Journal of Medicine & Science in Sports 31:3, pages 542-552.
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Borja Sañudo, Adérito Seixas, Rainer Gloeckl, Jörn Rittweger, Rainer Rawer, Redha Taiar, Eddy A. van der Zee, Marieke J.G. van Heuvelen, Ana Cristina Lacerda, Alessandro Sartorio, Michael Bemben, Darryl Cochrane, Trentham Furness, Danúbia de Sá-Caputo & Mario Bernardo-Filho. (2020) Potential Application of Whole Body Vibration Exercise for Improving the Clinical Conditions of COVID-19 Infected Individuals: A Narrative Review from the World Association of Vibration Exercise Experts (WAVex) Panel. International Journal of Environmental Research and Public Health 17:10, pages 3650.
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Anson M. Blanks, Paula Rodriguez-Miguelez, Jacob Looney, Matthew A. Tucker, Jinhee Jeong, Jeffrey Thomas, Marsha Blackburn, David W. Stepp, Neal J. Weintraub & Ryan A. Harris. (2020) Whole body vibration elicits differential immune and metabolic responses in obese and normal weight individuals. Brain, Behavior, & Immunity - Health 1, pages 100011.
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C. Zhang, K.K. Chen, X.H. Zhao, C. Wang & Z.Y. Geng. (2019) Effect of l-theanine on the growth performance, immune function, and jejunum morphology and antioxidant status of ducks. Animal 13:6, pages 1145-1153.
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Wei-Jie Zeng, Zhi Tan, Xing-Fei Lai, Ya-Nan Xu, Chun-Lin Mai, Jun Zhang, Zhen-Jia Lin, Xian-Guo Liu, Shi-Li Sun & Li-Jun Zhou. (2018) Topical delivery of l -theanine ameliorates TPA-induced acute skin inflammation via downregulating endothelial PECAM-1 and neutrophil infiltration and activation. Chemico-Biological Interactions 284, pages 69-79.
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Muhammad Saeed, Xu Yatao, Faiz-ul Hassan, Muhammad Arain, Mohamed Abd El-Hack, Ahmed Noreldin & Chao Sun. (2018) Influence of Graded Levels of l-Theanine Dietary Supplementation on Growth Performance, Carcass Traits, Meat Quality, Organs Histomorphometry, Blood Chemistry and Immune Response of Broiler Chickens. International Journal of Molecular Sciences 19:2, pages 462.
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Jackson Williams, Jane Kellett, Paul Roach, Andrew McKune, Duane Mellor, Jackson Thomas & Nenad Naumovski. (2016) l-Theanine as a Functional Food Additive: Its Role in Disease Prevention and Health Promotion. Beverages 2:2, pages 13.
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Alexandra Sakelliou, Ioannis G. Fatouros, Ioannis Athanailidis, Dimitrios Tsoukas, Athanasios Chatzinikolaou, Dimitris Draganidis, Athanasios Z. Jamurtas, Christina Liacos, Ioannis Papassotiriou, Dimitrios Mandalidis, Kimon Stamatelopoulos, Meletios A. Dimopoulos & Asimina Mitrakou. (2016) Evidence of a Redox-Dependent Regulation of Immune Responses to Exercise-Induced Inflammation. Oxidative Medicine and Cellular Longevity 2016, pages 1-19.
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Kenji A.K. Tanaka, Shigekazu Kurihara, Tetsuro Shibakusa, Yasumasa Chiba & Takashi Mikami. (2015) Cystine improves survival rates in a LPS-induced sepsis mouse model. Clinical Nutrition 34:6, pages 1159-1165.
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Katsuhiko SuzukiMasaki TakahashiChia-Yang LiShiuan-Pey LinMiki TomariCecilia M. ShingShih-Hua Fang. (2015) The acute effects of green tea and carbohydrate coingestion on systemic inflammation and oxidative stress during sprint cycling. Applied Physiology, Nutrition, and Metabolism 40:10, pages 997-1003.
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Masaru Ohtani. (2014) Effects of Peptides and Amino Acids Derived from Oyster on Blood Lipids. Journal of Nutritional Health & Food Engineering 1:5.
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Shiuan-Pey Lin, Chia-Yang Li, Katsuhiko Suzuki, Chen-Kang Chang, Kuei-Ming Chou & Shih-Hua Fang. (2014) Green Tea Consumption after Intense Taekwondo Training Enhances Salivary Defense Factors and Antibacterial Capacity. PLoS ONE 9:1, pages e87580.
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Shigekazu Kurihara, Tetsuro Shibakusa & Kenji AK Tanaka. (2013) Cystine and theanine: amino acids as oral immunomodulative nutrients. SpringerPlus 2:1.
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Hui Yang, Wenzhe Li, Huiyi Yu, Ruiqi Yuan, Yang Yang, Kingston Pung, Ping Li & Lei Xue. (2013) Physiological Effects of l-Theanine on Drosophila melanogaster. Molecules 18:11, pages 13175-13187.
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Tomohiro Miyachi, Takashi Tsuchiya, Atsushi Oyama, Takahiro Tsuchiya, Naomi Abe, Atsuko Sato, Yasumasa Chiba, Shigekazu Kurihara, Tetsuro Shibakusa & Takashi Mikami. (2012) Perioperative Oral Administration of Cystine and Theanine Enhances Recovery After Distal Gastrectomy. Journal of Parenteral and Enteral Nutrition 37:3, pages 384-391.
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Liang Zhang, Zheng-Zhu Zhang, Ya-Ning Lu, Jing-Song Zhang & Victor R. Preedy. 2013. Tea in Health and Disease Prevention. Tea in Health and Disease Prevention 425 435 .
Wolfgang Gunzer, Manuela Konrad & Elisabeth Pail. (2012) Exercise-Induced Immunodepression in Endurance Athletes and Nutritional Intervention with Carbohydrate, Protein and Fat — What Is Possible, What Is Not?. Nutrients 4:9, pages 1187-1212.
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Tetsuro Shibakusa, Takashi Mikami, Shigekazu Kurihara, Yasumasa Chiba, Takashi Tsuchiya, Tomohiro Miyachi, Atsushi Oyama, Kenji A.K. Tanaka & Naoto Koyama. (2012) Enhancement of postoperative recovery by preoperative oral co-administration of the amino acids, cystine and theanine, in a mouse surgical model. Clinical Nutrition 31:4, pages 555-561.
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N. H. Kim, H. J. Jeong & H. M. Kim. (2011) Theanine is a candidate amino acid for pharmacological stabilization of mast cells. Amino Acids 42:5, pages 1609-1618.
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