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Research Article

Examination of the efficacy of acute L-alanyl-L-glutamine ingestion during hydration stress in endurance exercise

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Article: 8 | Published online: 06 May 2022

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Chad M. Kerksick, Colin D. Wilborn, Michael D. Roberts, Abbie Smith-Ryan, Susan M. Kleiner, Ralf Jäger, Rick Collins, Mathew Cooke, Jaci N. Davis, Elfego Galvan, Mike Greenwood, Lonnie M. Lowery, Robert Wildman, Jose Antonio & Richard B. Kreider. (2018) ISSN exercise & sports nutrition review update: research & recommendations. Journal of the International Society of Sports Nutrition 15:1.
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Peter Bond. (2016) Regulation of mTORC1 by growth factors, energy status, amino acids and mechanical stimuli at a glance. Journal of the International Society of Sports Nutrition 13:1.
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Gabriel J. Pruna, Jay R. Hoffman, William P. McCormack, Adam R. Jajtner, Jeremy R. Townsend, Jonathan D. Bohner, Michael B. La Monica, Adam J. Wells, Jeffrey R. Stout, Maren S. Fragala & David H. Fukuda. (2016) Effect of acute L-Alanyl-L-Glutamine and electrolyte ingestion on cognitive function and reaction time following endurance exercise. European Journal of Sport Science 16:1, pages 72-79.
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William P. McCormack, Jay R. Hoffman, Gabriel J. Pruna, Adam R. Jajtner, Jeremy R. Townsend, Jeffrey R. Stout, Maren S. Fragala & David H. Fukuda. (2015) Effects of l-Alanyl-l-Glutamine Ingestion on One-Hour Run Performance. Journal of the American College of Nutrition 34:6, pages 488-496.
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Jay R Hoffman, David R Williams, Nadia S Emerson, Mattan W Hoffman, Adam J Wells, Daniele M McVeigh, William P McCormack, Gerald T Mangine, Adam M Gonzalez & Maren S Fragala. (2012) L-alanyl-L-glutamine ingestion maintains performance during a competitive basketball game. Journal of the International Society of Sports Nutrition 9:1.
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Allyson L Walsh, Adam M Gonzalez, Nicholas A Ratamess, Jie Kang & Jay R Hoffman. (2010) Improved time to exhaustion following ingestion of the energy drink Amino Impact™. Journal of the International Society of Sports Nutrition 7:1.
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Shannon L. Jordan, Fernando Naclerio & Julio Benjamin Morales. 2023. The Active Female. The Active Female 399 423 .
Mindy Millard-Stafford, Teresa K. Snow, Michael L. Jones & HyunGyu Suh. (2021) The Beverage Hydration Index: Influence of Electrolytes, Carbohydrate and Protein. Nutrients 13:9, pages 2933.
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Mitchell E. Zaplatosch & William M. Adams. (2020) The Effect of Acute Hypohydration on Indicators of Glycemic Regulation, Appetite, Metabolism and Stress: A Systematic Review and Meta-Analysis. Nutrients 12:9, pages 2526.
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Theodore P. Parthimos, Kleopatra H. Schulpis, Yannis L. Loukas & Yannis Dotsikas. (2020) Increased blood concentrations of neurotransmission amino acids and modulation of specific enzyme activities after resistance and endurance exercise. Sport Sciences for Health 16:2, pages 217-226.
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Kurt J. Sollanek, Jeffery S. Staab, Robert W. Kenefick & Samuel N. Cheuvront. (2020) Biological variation of arginine vasopressin. European Journal of Applied Physiology 120:3, pages 635-642.
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Audrey Yule Coqueiro, Marcelo Macedo Rogero & Julio Tirapegui. (2019) Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition. Nutrients 11:4, pages 863.
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Fatima Al-Khelaifi, David Abraham, Ilhame Diboun & Mohamed A. Elrayess. 2019. Sports, Exercise, and Nutritional Genomics. Sports, Exercise, and Nutritional Genomics 539 566 .
Brian M. Zanghi & Cari L. Gardner. (2018) Total Water Intake and Urine Measures of Hydration in Adult Dogs Drinking Tap Water or a Nutrient-Enriched Water. Frontiers in Veterinary Science 5.
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Raquel Raizel & Julio Tirapegui. (2018) Role of glutamine, as free or dipeptide form, on muscle recovery from resistance training: a review study. Nutrire 43:1.
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Brian M. Zanghi, Patrick J. Robbins, Meghan T. Ramos & Cynthia M. Otto. (2018) Working Dogs Drinking a Nutrient-Enriched Water Maintain Cooler Body Temperature and Improved Pulse Rate Recovery After Exercise. Frontiers in Veterinary Science 5.
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Kurt J Sollanek, Matthew Tsurumoto, Sadasivan Vidyasagar, Robert W Kenefick & Samuel N Cheuvront. (2018) Neither body mass nor sex influences beverage hydration index outcomes during randomized trial when comparing 3 commercial beverages. The American Journal of Clinical Nutrition 107:4, pages 544-549.
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Marta Stachowicz & Anna Lebiedzińska. (2016) The effect of diet components on the level of cortisol. European Food Research and Technology 242:12, pages 2001-2009.
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Flavia Meyer, Zbigniew Szygula & Boguslaw WilkLuis Aragón-Vargas. 2015. Fluid Balance, Hydration, and Athletic Performance. Fluid Balance, Hydration, and Athletic Performance 397 425 .
Christina WuTomoko S. KatoRuiping JiCynthia ZizolaDanielle L. BrunjesYue DengHirokazu AkashiHilary F. ArmstrongPeter J. KennelTiffany ThomasDaniel E. FormanJennifer HallAalap ChokshiMatthew N. BartelsDonna ManciniDavid SeresP. Christian Schulze. (2015) Supplementation of l -Alanyl- l -Glutamine and Fish Oil Improves Body Composition and Quality of Life in Patients With Chronic Heart Failure . Circulation: Heart Failure 8:6, pages 1077-1087.
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Wanyi Wang, Ran Hee Choi, Geoffrey J. Solares, Hung-Min Tseng, Zhenping Ding, Kyoungrae Kim & John L. Ivy. (2015) l-Alanylglutamine inhibits signaling proteins that activate protein degradation, but does not affect proteins that activate protein synthesis after an acute resistance exercise. Amino Acids 47:7, pages 1389-1398.
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Andreas Karau & Ian Grayson. 2014. Biotechnology of Food and Feed Additives. Biotechnology of Food and Feed Additives 189 228 .
Wolfgang Gunzer, Manuela Konrad & Elisabeth Pail. (2012) Exercise-Induced Immunodepression in Endurance Athletes and Nutritional Intervention with Carbohydrate, Protein and Fat — What Is Possible, What Is Not?. Nutrients 4:9, pages 1187-1212.
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Roger C. Harris, Jay R. Hoffman, Adrian Allsopp & Naomi B.H. Routledge. (2012) l-glutamine absorption is enhanced after ingestion of l-alanylglutamine compared with the free amino acid or wheat protein. Nutrition Research 32:4, pages 272-277.
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Jens O. Krömer, Stefanie Dietmair, Shana S. Jacob & Lars K. Nielsen. (2011) Quantification of l-alanyl-l-glutamine in mammalian cell culture broth: Evaluation of different detectors. Analytical Biochemistry 416:1, pages 129-131.
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