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Journal of the International Society of Sports Nutrition Volume 9, 2012 - Issue 1
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Research Article

Postprandial leucine and insulin responses and toxicological effects of a novel whey protein hydrolysate-based supplement in rats

Ryan G Toedebusch1 Department of Biomedical SciencesCollege of Veterinary Medicine, University of MissouriColumbiaMOUSA
,
Thomas E Childs1 Department of Biomedical SciencesCollege of Veterinary Medicine, University of MissouriColumbiaMOUSA
,
Shari R Hamilton2 Research Animal Diagnostics Laboratory (RADIL)ColumbiaMOUSA
,
Jan R Crowley3 NIH/NCRR Mass Spectrometry ResourceWashington UniversitySt. LouisMOUSA;4 School of Medicine, Division of EndocrinologyMetabolism, Lipid Research, Washington UniversitySt. LouisMOUSA
,
Frank W Booth1 Department of Biomedical SciencesCollege of Veterinary Medicine, University of MissouriColumbiaMOUSA;5 Dalton Cardiovascular Research CenterUniversity of MissouriColumbiaMOUSA;6 Department of Medical Pharmacology and PhysiologySchool of Medicine, University of MissouriColumbiaMOUSA;7 Department of Nutrition and Exercise PhysiologyCollege of Environmental Health Sciences, University of MissouriColumbiaMOUSA
&
Michael D Roberts1 Department of Biomedical SciencesCollege of Veterinary Medicine, University of MissouriColumbiaMOUSACorrespondence[email protected]
Article: 24 | Published online: 01 Apr 2022

Citations (22)

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Read on this site (2)

Aslı Yiğit, Paulina Bielska, Dorota Cais-Sokolińska & Gülhan Samur. (2023) Whey proteins as a functional food: Health effects, functional properties, and applications in food. Journal of the American Nutrition Association 42:8, pages 758-768.
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Christopher Brooks Mobley, Carlton D Fox, Brian S Ferguson, Corrie A Pascoe, James C Healy, Jeremy S McAdam, Christopher M Lockwood & Michael D Roberts. (2015) Effects of protein type and composition on postprandial markers of skeletal muscle anabolism, adipose tissue lipolysis, and hypothalamic gene expression. Journal of the International Society of Sports Nutrition 12:1.
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Articles from other publishers (20)

Chinaza Godswill Awuchi. 2022. Food and Agricultural Byproducts as Important Source of Valuable Nutraceuticals. Food and Agricultural Byproducts as Important Source of Valuable Nutraceuticals 159 183 .
Shayanti Minj & Sanjeev Anand. (2020) Whey Proteins and Its Derivatives: Bioactivity, Functionality, and Current Applications. Dairy 1:3, pages 233-258.
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Yusuke Kamiya, Shohei Otsuka, Tomonori Miura, Manae Yoshizawa, Ayane Nakano, Miyu Iwasaki, Yui Kobayashi, Makiko Shimizu, Masato Kitajima, Fumiaki Shono, Kimito Funatsu & Hiroshi Yamazaki. (2020) Physiologically Based Pharmacokinetic Models Predicting Renal and Hepatic Concentrations of Industrial Chemicals after Virtual Oral Doses in Rats. Chemical Research in Toxicology 33:7, pages 1736-1751.
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M. Dolores Arenas Jiménez. (2019) When the sport stops being health: Diets, supplements and substances to increase the performance and its relation with the kidney. Nefrología (English Edition) 39:3, pages 223-226.
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M. Dolores Arenas Jiménez. (2019) Cuando el deporte deja de ser salud: dietas, suplementos y sustancias para aumentar el rendimiento y su relación con el riñón. Nefrología 39:3, pages 223-226.
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Zahra Sohrabi, Mohammad Hassan Eftekhari, Mohammad Hadi Eskandari, Abbas Rezaianzadeh & Mohammad Mahdi Sagheb. (2016) Intradialytic Oral Protein Supplementation and Nutritional and Inflammation Outcomes in Hemodialysis: A Randomized Controlled Trial. American Journal of Kidney Diseases 68:1, pages 122-130.
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Eduardo O. De Souza, Ryan P. Lowery, Jacob M. Wilson, Matthew H. Sharp, Christopher Brooks Mobley, Carlton D. Fox, Hector L. Lopez, Kevin A. Shields, Jacob T. Rauch, James C. Healy, Richard M. Thompson, Jacob A. Ormes, Jordan M. Joy & Michael D. Roberts. (2016) Effects of Arachidonic Acid Supplementation on Acute Anabolic Signaling and Chronic Functional Performance and Body Composition Adaptations. PLOS ONE 11:5, pages e0155153.
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Kianoush Saberi, Mohammad Amin Gorji Mahlabani, Mohammad Tashayoie & Farinaz Nasiri Nejad. (2016) The Relationship Between Creatine and Whey Protein Supplements Consumption and Anesthesia in Rats. Anesthesiology and Pain Medicine 6:1.
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Jose Antonio, Anya Ellerbroek, Tobin Silver, Leonel Vargas, Armando Tamayo, Richard Buehn & Corey A. Peacock. (2016) A High Protein Diet Has No Harmful Effects: A One-Year Crossover Study in Resistance-Trained Males. Journal of Nutrition and Metabolism 2016, pages 1-5.
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A. B. Nongonierma, M. B. O’Keeffe & R. J. FitzGerald. 2016. Advanced Dairy Chemistry. Advanced Dairy Chemistry 417 482 .
Seema Patel. (2015) Functional food relevance of whey protein: A review of recent findings and scopes ahead. Journal of Functional Foods 19, pages 308-319.
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Seema Patel. (2015) Emerging trends in nutraceutical applications of whey protein and its derivatives. Journal of Food Science and Technology 52:11, pages 6847-6858.
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Alice B. Nongonierma & Richard J. FitzGerald. (2015) Milk proteins as a source of tryptophan-containing bioactive peptides. Food & Function 6:7, pages 2115-2127.
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C Brooks Mobley, Ryan G Toedebusch, Christopher M Lockwood, Alexander J Heese, Conan Zhu, Anna E Krieger, Clayton L Cruthirds, John C Hofheins, Joseph M Company, Charles E Wiedmeyer, Dae Y Kim, Frank W Booth & Michael D Roberts. (2014) Herbal adaptogens combined with protein fractions from bovine colostrum and hen egg yolk reduce liver TNF-α expression and protein carbonylation in Western diet feeding in rats. Nutrition & Metabolism 11:1.
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Blanca Hernández-Ledesma, María José García-Nebot, Samuel Fernández-Tomé, Lourdes Amigo & Isidra Recio. (2014) Dairy protein hydrolysates: Peptides for health benefits. International Dairy Journal 38:2, pages 82-100.
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Jan Stanstrup, Jakob E. Rasmussen, Christian Ritz, Jens Holmer-Jensen, Kjeld Hermansen & Lars Ove Dragsted. (2013) Intakes of whey protein hydrolysate and whole whey proteins are discriminated by LC–MS metabolomics. Metabolomics 10:4, pages 719-736.
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Michael D. RobertsClayton L. CruthirdsChristopher M. LockwoodKirk PappanThomas E. ChildsJoseph M. CompanyJacob D. BrownRyan G. ToedebuschFrank W. Booth. (2014) Comparing serum responses to acute feedings of an extensively hydrolyzed whey protein concentrate versus a native whey protein concentrate in rats: a metabolomics approach. Applied Physiology, Nutrition, and Metabolism 39:2, pages 158-167.
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Abbie E. Smith-RyanDavid H. FukudaJeffrey R. StoutKristina L. Kendall. (2014) The influence of β-alanine supplementation on markers of exercise-induced oxidative stress. Applied Physiology, Nutrition, and Metabolism 39:1, pages 38-46.
Crossref
Joseph M. CompanyMichael D. RobertsRyan G. ToedebuschClayton L. CruthirdsFrank W. Booth. (2013) Sudden decrease in physical activity evokes adipocyte hyperplasia in 70- to 77-day-old rats but not 49- to 56-day-old rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 305:12, pages R1465-R1478.
Crossref
Celine Gaudel, Alice B. Nongonierma, Samuel Maher, Sarah Flynn, Mauricio Krause, Brian A. Murray, Phillip M. Kelly, Alan W. Baird, Richard J. FitzGerald & Philip Newsholme. (2013) A Whey Protein Hydrolysate Promotes Insulinotropic Activity in a Clonal Pancreatic β-Cell Line and Enhances Glycemic Function in ob/ob Mice1–3. The Journal of Nutrition 143:7, pages 1109-1114.
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