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Original Articles

Effect of Dietary Conjugated Linoleic Acid on Phorbol Ester-Induced PGE2 Production and Hyperplasia in Mouse Epidermis

Pages 132-138 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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D. Hattis, M. Chu, N. Rahmioglu, R. Goble, P. Verma, K. Hartman & M. Kozlak. (2009) A Preliminary Operational Classification System for Nonmutagenic Modes of Action for Carcinogenesis. Critical Reviews in Toxicology 39:2, pages 97-138.
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KI WON LEE, HYONG JOO LEE, HONG YON CHO & YOUNG JUN KIM. (2005) Role of the Conjugated Linoleic Acid in the Prevention of Cancer. Critical Reviews in Food Science and Nutrition 45:2, pages 135-144.
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SailendraN. Nichenametla, ElizabethH. South & JerryH. Exon. (2004) Interaction of Conjugated Linoleic Acid, Sphingomyelin, and Butyrate on Formation of Colonic Aberrant Crypt Foci and Immune Functions in Rats. Journal of Toxicology and Environmental Health, Part A 67:6, pages 469-481.
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David W. L. Ma, Catherine J. Field & Michael T. Clandinin. (2002) An Enriched Mixture of Trans-10,Cis-12-CLA Inhibits Linoleic Acid Metabolism and PGE2 Synthesis in MDA-MB-231 Cells. Nutrition and Cancer 44:2, pages 203-212.
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Articles from other publishers (67)

Mariângela Bueno Cordeiro Maldonado, Valeska de Castro Lourenço, Lucas de Oliveira Bezerra, Isabella Rio Feltrin, Adriano Felipe Mendes, Cecilia Constantino Rocha, Guilherme Pugliesi, Alan D. Ealy, Claudia Maria Bertan Membrive & Marcelo Fábio Gouveia Nogueira. (2023) Conjugated linoleic acid supplementation changes prostaglandin concentration ratio and alters the expression of genes involved in maternal-fetal recognition from bovine trophoblast cells in vitro. Theriogenology 206, pages 87-95.
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Rakesh Kapoor & Martin Reaney. 2005. Bailey's Industrial Oil and Fat Products. Bailey's Industrial Oil and Fat Products 1 30 .
Laura den Hartigh. (2019) Conjugated Linoleic Acid Effects on Cancer, Obesity, and Atherosclerosis: A Review of Pre-Clinical and Human Trials with Current Perspectives. Nutrients 11:2, pages 370.
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G. Wielgosz-Collin, M. Kendel & A. Couzinet-Mossion. 2016. Seaweed in Health and Disease Prevention. Seaweed in Health and Disease Prevention 185 221 .
A. Makol, S. Torrecillas, M.J. Caballero, A. Fernández-Vaquero & M.S. Izquierdo. (2012) Effect of long term feeding with conjugated linoleic acid (CLA) in growth performance and lipid metabolism of European sea bass (Dicentrarchus labrax). Aquaculture 368-369, pages 129-137.
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Andrew P. Wakefield, Malcolm R. Ogborn, Naser Ibrahim & Harold M. Aukema. (2012) A dietary conjugated linoleic acid treatment that slows renal disease progression alters renal cyclooxygenase-2-derived prostanoids in the Han: SPRD-cy rat. The Journal of Nutritional Biochemistry 23:8, pages 908-914.
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Ding-Ding Guo, Seong-Ho Hong, Hu-Lin Jiang, Ji-Hye Kim, Arash Minai-Tehrani, Ji-Eun Kim, Ji-Young Shin, Tao Jiang, You-Kyoung Kim, Yun-Jaie Choi, Chong-Su Cho & Myung-Haing Cho. (2012) Synergistic effects of Akt1 shRNA and paclitaxel-incorporated conjugated linoleic acid-coupled poloxamer thermosensitive hydrogel on breast cancer. Biomaterials 33:7, pages 2272-2281.
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Dongping Liu, Guiping Kong, Quan Cheng Chen, Guanghui Wang, Jie Li, Yang Xu, Ting lin, Yingpu Tian, Xiaokun Zhang, Xinsheng Yao, Gensheng Feng, Zhongxian Lu & Haifeng Chen. (2011) Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2. Bioorganic & Medicinal Chemistry Letters 21:22, pages 6833-6837.
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Rui Rosa, Ana M. Andrade, Narcisa M. Bandarra & Maria L. Nunes. (2010) Physiological and biochemical effects of conjugated linoleic acid and its use in aquaculture. Reviews in Aquaculture 2:2, pages 59-72.
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Jianxia Guo, Changlu Wang, Zhijian Wu, Mianhua Chen, Fengjuan Li & Yurong Wang. (2010) Purification of Essential Linoleic Acid from Pinus armandi franch Seed Oil by Silver-Silica Gel Chromatography Column. Purification of Essential Linoleic Acid from Pinus armandi franch Seed Oil by Silver-Silica Gel Chromatography Column.
Alejandro Ruiz-Rodriguez, Guillermo Reglero & Elena Ibañez. (2010) Recent trends in the advanced analysis of bioactive fatty acids. Journal of Pharmaceutical and Biomedical Analysis 51:2, pages 305-326.
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Carolina Ramírez-Santana, Francisco J. Pérez-Cano, Cristina Castellote, Margarida Castell, Montserrat Rivero, María Rodríguez-Palmero & Àngels Franch. (2009) Higher immunoglobulin production in conjugated linoleic acid-supplemented rats during gestation and suckling. British Journal of Nutrition 102:6, pages 858-868.
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Kristine M Peterson, Marianne O'Shea, Wiro Stam, Inge CM Mohede, James T Patrie & Frederick G Hayden. (2009) Effects of dietary supplementation with conjugated linoleic acid on experimental human rhinovirus infection and illness. Antiviral Therapy 14:1, pages 33-43.
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Kimberly M. Hargrave‐Barnes, Michael J. Azain & Jess L. Miner. (2012) Conjugated Linoleic Acid‐induced Fat Loss Dependence on Δ6‐desaturase or Cyclooxygenase. Obesity 16:10, pages 2245-2252.
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Bruce Watkins & Yong Li. 2008. Food Lipids. Food Lipids.
Klaus W.J. Wahle, Marie Goua, Simona D'Urso & Steven D. Heys. 2008. Trans Fatty Acids. Trans Fatty Acids 54 101 .
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Ding-Ding Guo, Hyun-Seuk Moon, Rohidas Arote, Ji-Hye Seo, Ji-Shan Quan, Yun-Jaie Choi & Chong-Su Cho. (2007) Enhanced anticancer effect of conjugated linoleic acid by conjugation with Pluronic F127 on MCF-7 breast cancer cells. Cancer Letters 254:2, pages 244-254.
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Martha A. Belury, Claudine J. Kavanaugh & Kai-Li Liu. (2007) Conjugated linoleic acid modulates phorbol ester–induced PPAR-δ and K-FABP mRNA expression in mouse skin. Nutrition Research 27:1, pages 48-55.
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Arunabh Bhattacharya, Jameela Banu, Mizanur Rahman, Jennifer Causey & Gabriel Fernandes. (2006) Biological effects of conjugated linoleic acids in health and disease. The Journal of Nutritional Biochemistry 17:12, pages 789-810.
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Lokenga Badinga & Elizabeth S. Greene. (2006) Physiological Properties of Conjugated Linoleic Acid and Implications for Human Health. Nutrition in Clinical Practice 21:4, pages 367-373.
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Stephanie C Degner, Michael Q Kemp, G. Tim Bowden & Donato F Romagnolo. (2006) Conjugated Linoleic Acid Attenuates Cyclooxygenase-2 Transcriptional Activity via an Anti-AP-1 Mechanism in MCF-7 Breast Cancer Cells. The Journal of Nutrition 136:2, pages 421-427.
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Kristina Hoffmann, Jörg Blaudszun, Claus Brunken, Wilhelm-Wolfgang Höpker, Roland Tauber & Hans Steinhart. (2005) Lipid class distribution of fatty acids including conjugated linoleic acids in healthy and cancerous parts of human kidneys. Lipids 40:10, pages 1057-1062.
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Yongsoon Park. 2005. Nutrition and Cancer Prevention. Nutrition and Cancer Prevention.
Daichi Oikawa, Tomonori Nakanishi, Yoshi-nori Nakamura, Takaya Yamamoto, Atsuko Yamaguchi, Nobuya Shiba, Hisao Iwamoto, Tetsuya Tachibana & Mitsuhiro Furuse. (2007) Modification of skin composition by conjugated linoleic acid alone or with combination of other fatty acids in mice. British Journal of Nutrition 94:2, pages 275-281.
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Kristina Hoffmann, Jörg Blaudszun, Claus Brunken, Roland Tauber, Wilhelm-Wolfgang Höpker & Hans Steinhart. (2005) Distribution of conjugated linoleic acid in total and subcellular fractions from normal and cancerous parts of human testes. Molecular Nutrition & Food Research 49:8, pages 756-762.
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Rakesh Kapoor, Martin Reaney & Neil D. Westcott. 2005. Bailey's Industrial Oil and Fat Products. Bailey's Industrial Oil and Fat Products.
A P Nugent, H M Roche, E J Noone, A Long, D K Kelleher & M J Gibney. (2005) The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers. European Journal of Clinical Nutrition 59:6, pages 742-750.
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Kristina Hoffmann, Jörg Blaudszun, Claus Brunken, Wilhelm-Wolfgang Höpker, Roland Tauber & Hans Steinhart. (2005) Distribution of polyunsaturated fatty acids including conjugated linoleic acids in total and subcellular fractions from healthy and cancerous parts of human kidneys. Lipids 40:3, pages 309-315.
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Kristina Hoffmann, J�rg Blaudszun, Claus Brunken, Wilhelm-Wolfgang H�pker, Roland Tauber & Hans Steinhart. (2005) New application of a subcellular fractionation method to kidney and testis for the determination of conjugated linoleic acid in selected cell organelles of healthy and cancerous human tissues. Analytical and Bioanalytical Chemistry 381:6, pages 1138-1144.
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K. Eder, N. Slomma, K. Becker & C. Brandsch. (2005) Effect of linseed oil supplementation on concentrations of (n‐3) polyunsaturated fatty acids in liver phospholipids of rats fed diets containing either an oil rich in conjugated linoleic acids, sunflower oil or high‐oleic acid sunflower oil. Journal of Animal Physiology and Animal Nutrition 89:1-2, pages 45-54.
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Klaus W.J. Wahle, Steven D. Heys & Dino Rotondo. (2004) Conjugated linoleic acids: are they beneficial or detrimental to health?. Progress in Lipid Research 43:6, pages 553-587.
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David Kritchevsky, Shirley A. Tepper, Scott Wright, Susanne K. Czarnecki, Thomas A. Wilson & Robert J. Nicolosi. (2004) Conjugated linoleic acid isomer effects in atherosclerosis: Growth and regression of lesions. Lipids 39:7, pages 611-616.
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Catherine J Field & Patricia D Schley. (2004) Evidence for potential mechanisms for the effect of conjugated linoleic acid on tumor metabolism and immune function: lessons from n−3 fatty acids. The American Journal of Clinical Nutrition 79:6, pages 1190S-1198S.
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Lisa Rainer & Cynthia J. Heiss. (2004) Conjugated linoleic acid: health implications and effects on body composition. Journal of the American Dietetic Association 104:6, pages 963-968.
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Wen-Ling Cheng, Chong-Kuei Lii, Haw-Wen Chen, Ting-Hui Lin & Kai-Li Liu. (2003) Contribution of Conjugated Linoleic Acid to the Suppression of Inflammatory Responses through the Regulation of the NF-κB Pathway. Journal of Agricultural and Food Chemistry 52:1, pages 71-78.
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Klaus Eder, Sabine Schleser, Karin Becker & Ramona Körting. (2003) Conjugated Linoleic Acids Lower the Release of Eicosanoids and Nitric Oxide from Human Aortic Endothelial Cells. The Journal of Nutrition 133:12, pages 4083-4089.
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Z. Cheng, M. Elmes, D.R.E. Abayasekara & D.C. Wathes. (2003) Effects of conjugated linoleic acid on prostaglandins produced by cells isolated from maternal intercotyledonary endometrium, fetal allantochorion and amnion in late pregnant ewes. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1633:3, pages 170-178.
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Claudine Kavanaugh & Jeffrey E. Green. (2003) The Use of Genetically Altered Mice for Breast Cancer Prevention Studies. The Journal of Nutrition 133:7, pages 2404S-2409S.
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William Christie, Jean-Louis Sébédio & Richard AdlofSebastiano Banni a, Klaus Wahle c & Steven Heys b. 2003. Advances in Conjugated Linoleic Acid Research. Advances in Conjugated Linoleic Acid Research.
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Satoshi KAWAHARA, Shin‐ichi TAKENOYAMA, Chizuko NAGATO, Michio MUGURUMA, Tatsumi ITO & Kiyoshi YAMAUCHI. (2008) Evaluation of beef tallow as a natural source of conjugated linoleic acid. Animal Science Journal 73:6, pages 533-538.
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Sunah Chung, Seyeon Park & Chul-Hak Yang. (2002) Unsaturated fatty acids bind Myc–Max transcription factor and inhibit Myc–Max–DNA complex formation. Cancer Letters 188:1-2, pages 153-162.
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Martha A. Belury. (2002) Inhibition of Carcinogenesis by Conjugated Linoleic Acid: Potential Mechanisms of Action. The Journal of Nutrition 132:10, pages 2995-2998.
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Hiroyuki Kohno, Rikako Suzuki, Ryoko Noguchi, Masashi Hosokawa, Kazuo Miyashita & Takuji Tanaka. (2005) Dietary Conjugated Linolenic Acid Inhibits Azoxymethane‐induced Colonic Aberrant Crypt Foci in Rats. Japanese Journal of Cancer Research 93:2, pages 133-142.
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