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Original Articles

Effects of Oral Administration of Tea, Decaffeinated Tea, and Caffeine on the Formation and Growth of Tumors in High-Risk SKH-1 Mice Previously Treated With Ultraviolet B Light

Pages 146-153 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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A. Uyar, Z. Yener & A. Dogan. (2016) Protective effects of Urtica dioica seed extract in aflatoxicosis: histopathological and biochemical findings. British Poultry Science 57:2, pages 235-245.
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Melissa M Camouse, Kaija K Hanneman, Edward P Conrad & Elma D Baron. (2005) Protective effects of tea polyphenols and caffeine. Expert Review of Anticancer Therapy 5:6, pages 1061-1068.
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Kenan Yıldızhan, Ömer Can Demirtaş, Ahmet Uyar, Zübeyir Huyut, Tahir Çakir, Ömer Faruk Keleş & Zabit Yener. (2020) Protective effects of Urtica dioica L. seed extract on liver tissue injury and antioxidant capacity in irradiated rats. Brazilian Journal of Pharmaceutical Sciences 56.
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Ana R. Fernandes, Ana C. Santos, Elena Sanchez-Lopez, Andjekla B. Kovačević, Marta Espina, Ana C. Calpena, Francisco J. Veiga, Maria L. Garcia & Eliana B. Souto. (2018) Neoplastic Multifocal Skin Lesions: Biology, Etiology, and Targeted Therapies for Nonmelanoma Skin Cancers. Skin Pharmacology and Physiology 31:2, pages 59-73.
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Haider N. Sultani, Rasha A. Ghazal, Alaa M. Hayallah, Loay K. Abdulrahman, Khaled Abu-Hammour, Shatha AbuHammad, Mutasem O. Taha & Malek A. Zihlif. (2017) Inhibitory Effects of New Mercapto Xanthine Derivatives in Human mcf7 and k562 Cancer Cell Lines. Journal of Heterocyclic Chemistry 54:1, pages 450-456.
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Hsiu-Mei Chiang, Chien-Wen Chen, Chien-Chia Chen, Hsiao-Wen Wang, Jhe-Hua Jhang, Ya-Han Huang & Kuo-Ching Wen. 2015. Coffee in Health and Disease Prevention. Coffee in Health and Disease Prevention 523 530 .
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Mysoon M. Al-Ansari & Abdelilah Aboussekhra. (2014) Caffeine Mediates Sustained Inactivation of Breast Cancer-Associated Myofibroblasts via Up-Regulation of Tumor Suppressor Genes. PLoS ONE 9:3, pages e90907.
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Meng‐I Yeh, Hsiu‐Chin Huang, Jia‐Horng Liaw, Min‐Chuan Huang, Kuei‐Fen Huang & Feng‐Lin Hsu. (2012) Dermal delivery by niosomes of black tea extract as a sunscreen agent. International Journal of Dermatology 52:2, pages 239-245.
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Chung S. Yang, Hong Wang, Guang Xun Li, Zhihong Yang, Fei Guan & Huanyu Jin. (2011) Cancer prevention by tea: Evidence from laboratory studies. Pharmacological Research 64:2, pages 113-122.
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Yao-Ping Lu, You-Rong Lou, Qing-Yun Peng, Paul Nghiem & Allan H. Conney. (2011) Caffeine Decreases Phospho-Chk1 (Ser317) and Increases Mitotic Cells with Cyclin B1 and Caspase 3 in Tumors from UVB-Treated Mice. Cancer Prevention Research 4:7, pages 1118-1125.
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Y.-R. Lou, Q.-Y. Peng, T. Li, C. M. Medvecky, Y. Lin, W. J. Shih, A. H. Conney, S. Shapses, G. C. Wagner & Y.-P. Lu. (2011) Effects of high-fat diets rich in either omega-3 or omega-6 fatty acids on UVB-induced skin carcinogenesis in SKH-1 mice. Carcinogenesis 32:7, pages 1078-1084.
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Axel H. Schönthal. (2011) Adverse effects of concentrated green tea extracts. Molecular Nutrition & Food Research 55:6, pages 874-885.
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F Tjeerdsma, MF Jonkman & JR Spoo. (2011) Temporary arrest of basal cell carcinoma formation in a patient with basal cell naevus syndrome (BCNS) since treatment with a gel containing various plant extracts. Journal of the European Academy of Dermatology and Venereology 25:2, pages 244-245.
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Y. Lou, Q. Peng, B. Nolan, G. C. Wagner & Y. Lu. (2009) Oral administration of caffeine during voluntary exercise markedly decreases tissue fat and stimulates apoptosis and cyclin B1 in UVB-treated skin of hairless p53-knockout mice. Carcinogenesis 31:4, pages 671-678.
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Song Liang Jin, Bing Rong Zhou & Dan Luo. (2009) Protective effect of epigallocatechin gallate on the immune function of dendritic cells after ultraviolet B irradiation. Journal of Cosmetic Dermatology 8:3, pages 174-180.
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Timothy P. Heffernan, Masaoki Kawasumi, Alessandra Blasina, Kenna Anderes, Allan H. Conney & Paul Nghiem. (2009) ATR–Chk1 Pathway Inhibition Promotes Apoptosis after UV Treatment in Primary Human Keratinocytes: Potential Basis for the UV Protective Effects of Caffeine. Journal of Investigative Dermatology 129:7, pages 1805-1815.
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Allan H. Conney, Pavel Kramata, You-Rong Lou & Yao-Ping Lu. (2008) Effect of Caffeine on UVB-induced Carcinogenesis, Apoptosis, and the Elimination of UVB-induced Patches of p53 Mutant Epidermal Cells in SKH-1 Mice. Photochemistry and Photobiology 84:2, pages 330-338.
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Ismail Celik & Yasin Tuluce. (2007) Elevation protective role of Camellia sinensis and Urtica dioica infusion against trichloroacetic acid‐exposed in rats . Phytotherapy Research 21:11, pages 1039-1044.
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Yao-Ping LuBonnie Nolan, You-Rong LouQing-Yun PengGeorge C. Wagner & Allan H. Conney. (2007) Voluntary exercise together with oral caffeine markedly stimulates UVB light-induced apoptosis and decreases tissue fat in SKH-1 mice. Proceedings of the National Academy of Sciences 104:31, pages 12936-12941.
Crossref
Myoung-Eun Han, Kyu-Hyun Park, Sun-Yong Baek, Bong-Seon Kim, Jae-Bong Kim, Hak-Jin Kim & Sae-Ock Oh. (2007) Inhibitory effects of caffeine on hippocampal neurogenesis and function. Biochemical and Biophysical Research Communications 356:4, pages 976-980.
Crossref
Ann M. Bode & Zigang Dong. (2007) The enigmatic effects of caffeine in cell cycle and cancer. Cancer Letters 247:1, pages 26-39.
Crossref
Shengmin Sang, Joshua D Lambert & Chung S Yang. (2006) Bioavailability and stability issues in understanding the cancer preventive effects of tea polyphenols. Journal of the Science of Food and Agriculture 86:14, pages 2256-2265.
Crossref
Yao-Ping Lu, You-Rong Lou, Bonnie Nolan, Qing-Yun Peng, Jian-Guo Xie, George C. Wagner & Allan H. Conney. (2006) Stimulatory effect of voluntary exercise or fat removal (partial lipectomy) on apoptosis in the skin of UVB light-irradiated mice. Proceedings of the National Academy of Sciences 103:44, pages 16301-16306.
Crossref
S.S. Bun, H. Bun, D. Guédon, C. Rosier & E. Ollivier. (2006) Effect of green tea extracts on liver functions in Wistar rats. Food and Chemical Toxicology 44:7, pages 1108-1113.
Crossref
Tina I. Wright, James M. Spencer & Franklin P. Flowers. (2006) Chemoprevention of nonmelanoma skin cancer. Journal of the American Academy of Dermatology 54:6, pages 933-946.
Crossref
Manjeshwar S. Baliga & Santosh K. Katiyar. (2006) Chemoprevention of photocarcinogenesis by selected dietary botanicals. Photochemical & Photobiological Sciences 5:2, pages 243-253.
Crossref
Andy H LeeMichelle L Fraser & Colin W Binns. (2005) Possible role for green tea in ovarian cancer prevention. Future Oncology 1:6, pages 771-777.
Crossref
Pavel Kramata, Yao-Ping Lu, You-Rong Lou, Julie L. Cohen, Meir Olcha, Sandy Liu & Allan H. Conney. (2005) Effect of administration of caffeine or green tea on the mutation profile in the p53 gene in early mutant p53-positive patches of epidermal cells induced by chronic UVB-irradiation of hairless SKH-1 mice. Carcinogenesis 26:11, pages 1965-1974.
Crossref
K. B. Michels, W. C. Willett, C. S. Fuchs & E. Giovannucci. (2005) Coffee, Tea, and Caffeine Consumption and Incidence of Colon and Rectal Cancer. JNCI Journal of the National Cancer Institute 97:4, pages 282-292.
Crossref
Wolfgang W. Huber & Wolfram Parzefall. 2005. Gluthione Transferases and Gamma-Glutamyl Transpeptidases. Gluthione Transferases and Gamma-Glutamyl Transpeptidases 307 341 .
Yao-Ping Lu, You-Rong Lou, Qing-Yun Peng, Jian-Guo Xie & Allan H. Conney. (2004) Stimulatory Effect of Topical Application of Caffeine on UVB-Induced Apoptosis in the Epidermis of p53 and Bax Knockout Mice. Cancer Research 64:14, pages 5020-5027.
Crossref
Allan H. Conney. (2004) Tailoring cancer chemoprevention regimens to the individual. Journal of Cellular Biochemistry 91:2, pages 277-286.
Crossref
Laura Michna, Yao-Ping Lu, You-Rong Lou, George C. Wagner & Allan H. Conney. (2003) Stimulatory effect of oral administration of green tea and caffeine on locomotor activity in SKH-1 mice. Life Sciences 73:11, pages 1383-1392.
Crossref
Sleem F'guyer, Farrukh Afaq & Hasan Mukhtar. (2003) Photochemoprevention of skin cancer by botanical agents. Photodermatology, Photoimmunology & Photomedicine 19:2, pages 56-72.
Crossref
Ann M. Bode & Zigang Dong. (2003) Signal Transduction Pathways: Targets for Green and Black Tea Polyphenols. BMB Reports 36:1, pages 66-77.
Crossref
Sheldon R. Pinnell. (2003) Cutaneous photodamage, oxidative stress, and topical antioxidant protection. Journal of the American Academy of Dermatology 48:1, pages 1-22.
Crossref
Yao-Ping Lu, You-Rong Lou, Jian-Guo Xie, Qing-Yun Peng, Jie Liao, Chung S. Yang, Mou-Tuan Huang & Allan H. Conney. (2002) Topical applications of caffeine or (−)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice. Proceedings of the National Academy of Sciences 99:19, pages 12455-12460.
Crossref
J.H Weisburger & Fung-Lung Chung. (2002) Mechanisms of chronic disease causation by nutritional factors and tobacco products and their prevention by tea polyphenols. Food and Chemical Toxicology 40:8, pages 1145-1154.
Crossref
Chung S. YangPius MaliakalXiaofeng Meng. (2002) Inhibition of Carcinogenesis by Tea. Annual Review of Pharmacology and Toxicology 42:1, pages 25-54.
Crossref
Iman A Hakim & Robin B Harris. (2001) Joint effects of citrus peel use and black tea intake on the risk of squamous cell carcinoma of the skin. BMC Dermatology 1:1.
Crossref
Gilberto Santana-Rios, Gayle Orner, Meirong Xu, Maria Izquierdo-Pulido & Roderick Dashwood. (2001) Inhibition by White Tea of 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine-Induced Colonic Aberrant Crypts in the F344 Rat. Nutrition and Cancer 41:1, pages 98-103.
Crossref
Gilberto Santana-Rios, Gayle A. Orner, Adams Amantana, Cynthia Provost, Shiau-Yin Wu & Roderick H. Dashwood. (2001) Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 495:1-2, pages 61-74.
Crossref
Chung S YangJanelle M LandauMou-Tuan HuangHarold L Newmark. (2001) I NHIBITION OF C ARCINOGENESIS BY D IETARY P OLYPHENOLIC C OMPOUNDS . Annual Review of Nutrition 21:1, pages 381-406.
Crossref
Katherine M.W. PistersRobert A. NewmanBrenda ColdmanDong M. ShinFadlo R. KhuriWaun Ki HongBonnie S. GlissonJin S. Lee. (2001) Phase I Trial of Oral Green Tea Extract in Adult Patients With Solid Tumors. Journal of Clinical Oncology 19:6, pages 1830-1838.
Crossref
Chung S. Yang, Guang-yu Yang, Jee Y. Chung, Mao-Jung Lee & Chuan Li. 2001. Nutrition and Cancer Prevention. Nutrition and Cancer Prevention 39 53 .
G. Galati, S. Teng, M.Y. Moridani, T.S. Chan & P.J. O'Brien. (2000) Cancer Chemoprevention and Apoptosis Mechanisms Induced by Dietary Polyphenolics. Drug Metabolism and Drug Interactions 17:1-4.
Crossref
Chung S. Yang, Jee Y. Chung, Guang‐Yu Yang, Chuan Li, Xiaofeng Meng & Mao‐Jung Lee. (2008) Mechanisms of inhibition of carcinogenesis by tea. BioFactors 13:1-4, pages 73-79.
Crossref
E. M. Williamson. (1999) Selected Bibliography. Phytotherapy Research 13:8, pages 702-708.
Crossref

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