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Original Articles

Effects of Garlic Oil and Its Organosulfur Compounds on the Activities of Hepatic Drug-Metabolizing and Antioxidant Enzymes in Rats Fed High- and Low-Fat Diets

Pages 160-166 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Tao Zeng, Cui-Li Zhang, Xiu-Lan Zhao & Ke-Qin Xie. (2013) The Roles of Garlic on the Lipid Parameters: A Systematic Review of the Literature. Critical Reviews in Food Science and Nutrition 53:3, pages 215-230.
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S. Mirunalini, C.R. Ramachandran & S. Nagini. (2004) Chemoprevention of Experimental Hamster Buccal Pouch Carcinogenesis by Garlic Oil. Journal of Herbs, Spices & Medicinal Plants 10:4, pages 89-101.
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S. Mirunalini, R. Kumaraguruparan, R. Subapriya & S. Nagini. (2004) Garlic Oil Enhances Hepatic and Blood Antioxidants During Hamster Buccal Pouch Carcinogenesis. Pharmaceutical Biology 42:3, pages 240-245.
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Gerlinde Scharf, Sonja Prustomersky, Siegfried Knasmüller, Rolf Schulte-Hermann & Wolfgang W. Huber. (2003) Enhancement of Glutathione and γ-Glutamylcysteine Synthetase, the Rate Limiting Enzyme of Glutathione Synthesis, by Chemoprotective Plant-Derived Food and Beverage Components in the Human Hepatoma Cell Line HepG2. Nutrition and Cancer 45:1, pages 74-83.
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Shufeng Zhou, Yihuai Gao, Wenqi Jiang, Min Huang, Anlong Xu & James W. Paxton. (2003) Interactions of Herbs with Cytochrome P450. Drug Metabolism Reviews 35:1, pages 35-98.
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Chong-Kuei Lii, Chu-Chyn Ou, Kai-Li Liu, Jer-Yuh Liu, Wea-Lung Lin & Haw-Wen Chen. (2000) Suppression of Altered Hepatic Foci Development by a High Fish Oil Diet Compared With a High Corn Oil Diet in Rats. Nutrition and Cancer 38:1, pages 50-59.
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Articles from other publishers (53)

Salah M. Aly, Mohamed A. Elatta, Asmaa A. Nasr & Mohamed Fathi. (2023) Efficacy of garlic and cinnamon as an alternative to chemotherapeutic agents in controlling Saprolegnia infection in Nile tilapia. Aquaculture and Fisheries.
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Jeanne M. Davidsen, Samuel M. Cohen, Gerhard Eisenbrand, Shoji Fukushima, Nigel J. Gooderham, F. Peter Guengerich, Stephen S. Hecht, Ivonne M.C.M. Rietjens, Thomas J. Rosol, Christie L. Harman, Danarubini Ramanan & Sean V. Taylor. (2023) FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil. Food and Chemical Toxicology 173, pages 113580.
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Yu-En Lin, Meng-Hsuan Lin, Ti-Yen Yeh, Yi-Syuan Lai, Kuan-Hung Lu, Huai-Syuan Huang, Fu-Chuo Peng, Shing-Hwa Liu & Lee-Yan Sheen. (2022) Genotoxicity and 28-day repeated dose oral toxicity study of garlic essential oil in mice. Journal of Traditional and Complementary Medicine 12:6, pages 536-544.
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Carlos César Patiño-Morales, Ricardo Jaime-Cruz, Concepción Sánchez-Gómez, Juan Carlos Corona, Estefani Yaquelin Hernández-Cruz, Ivia Kalinova-Jelezova, José Pedraza-Chaverri, Perla D. Maldonado, Carlos Alfredo Silva-Islas & Marcela Salazar-García. (2021) Antitumor Effects of Natural Compounds Derived from Allium sativum on Neuroblastoma: An Overview. Antioxidants 11:1, pages 48.
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Salim M. A. Bastaki, Shreesh Ojha, Huba Kalasz & E. Adeghate. (2021) Chemical constituents and medicinal properties of Allium species. Molecular and Cellular Biochemistry 476:12, pages 4301-4321.
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Zeinab Farhat, Pamela A. Hershberger, Jo L. Freudenheim, Manoj J. Mammen, Rachael Hageman Blair, Diana S. Aga & Lina Mu. (2021) Types of garlic and their anticancer and antioxidant activity: a review of the epidemiologic and experimental evidence. European Journal of Nutrition 60:7, pages 3585-3609.
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Mustafa Shukry, Saqer S. Alotaibi, Sarah M. Albogami, Nora Fathallah, Foad Farrag, Mahmoud A. O. Dawood & Mahmoud S. Gewaily. (2020) Garlic Alleviates the Injurious Impact of Cyclosporine-A in Male Rats through Modulation of Fibrogenic and Steroidogenic Genes. Animals 11:1, pages 64.
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Hesham Farouk Hasan, Gehan Roushdy Abdel-Hamid & Sahar Ismail Ebrahim. (2020) Antioxidant and Anti-Inflammatory Effects of Diallyl Disulfide on Hepatotoxicity Induced by Cyclophosphamide in Rats. Natural Product Communications 15:10, pages 1934578X2096908.
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Jinning Suo, Cuili Zhang, Pin Wang, Liyan Hou, Qingshan Wang & Xiulan Zhao. (2019) Allyl Sulfide Counteracts 1-Bromopropane-Induced Neurotoxicity by Inhibiting Neuroinflammation and Oxidative Stress. Toxicological Sciences 167:2, pages 397-407.
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Min Gao, Rui Wang, Fabiao Yu, Bowei Li & Lingxin Chen. (2018) Imaging of intracellular sulfane sulfur expression changes under hypoxic stress via a selenium-containing near-infrared fluorescent probe . Journal of Materials Chemistry B 6:41, pages 6637-6645.
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Ning Zhao, Min-Jie Guan, Ming-Jun Li & Tao Zeng. (2018) Effects of garlic-derived lipid soluble organosulfur compounds on hematological parameters in mice. Journal of Functional Foods 46, pages 85-89.
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Adejoke Elizabeth Memudu, Ibukun Dorcas Akinrinade & Olalekan Michael Ogundele. (2015) Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat. Asian Pacific Journal of Tropical Biomedicine 5:4, pages 319-323.
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Tao Zeng, Yang Li, Cui-Li Zhang, Li-Hua Yu, Zhen-Ping Zhu, Xiu-Lan Zhao & Ke-Qin Xie. (2013) Garlic Oil Suppressed the Hematological Disorders Induced by Chemotherapy and Radiotherapy in Tumor-Bearing Mice. Journal of Food Science 78:6, pages H936-H942.
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Andres A. Caro, Luke W. Adlong, Samuel J. Crocker, Michael W. Gardner, Emily F. Luikart & Liz U. Gron. (2012) Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria. Toxicology Letters 214:2, pages 166-174.
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