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Original Articles

Citrus Peel Use Is Associated With Reduced Risk of Squamous Cell Carcinoma of the Skin

Pages 161-168 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Andrew R. Marley, Ming Li, Victoria L. Champion, Yiqing Song, Jiali Han & Xin Li. (2022) Citrus Consumption and Risk of Non-Melanoma Skin Cancer in the UK Biobank. Nutrition and Cancer 74:3, pages 810-815.
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Silvia Isabel Rech Franke, Temenouga Nikolova Guecheva, João Antonio Pêgas Henriques & Daniel Prá. (2013) Orange Juice and Cancer Chemoprevention. Nutrition and Cancer 65:7, pages 943-953.
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StevenP. Stratton, Kathy Lynn Saboda, PaulB. Myrdal, Abhishek Gupta, NajaE. McKenzie, Chris Brooks, StuartJ. Salasche, JamesA. Warneke, James Ranger-Moore, PaulD. Bozzo, James Blanchard, JanineG. Einspahr, RobertT. Dorr, Norman Levine & DavidS. Alberts. (2008) Phase 1 Study of Topical Perillyl Alcohol Cream for Chemoprevention of Skin Cancer. Nutrition and Cancer 60:3, pages 325-330.
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Parker Magin & Jon Adams. (2007) Complementary and alternative medicines: use in skin diseases. Expert Review of Dermatology 2:1, pages 41-49.
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Articles from other publishers (48)

Deepa Mandal & Tithi Parija. (2022) Anticancer Mechanism of D-limonene: An Updated Review and Therapeutic Possibilities. Current Cancer Therapy Reviews 18:3, pages 193-201.
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Karen Hye-cheon Kim Yeary, Amanda J. Quisenberry, Marissa G. Hall, Han Yu, Whitney Ann E. Henry, Elisa Marie Rodriguez & Jamie M. Zoellner. (2022) Sweet Beverages and Cancer: A Scoping Review of Quantitative Studies. Cancer Prevention Research 15:6, pages 377-390.
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Abdur Rauf, Mohammad Ali Shariati, Muhammad Imran, Kashif Bashir, Shahid Ali Khan, Saikat Mitra, Talha Bin Emran, Kamala Badalova, Md. Sahab Uddin, Mohammad S. Mubarak, Abdullah S. M. Aljohani, Fahad A. Alhumaydhi, Marina Derkho, Serdar Korpayev & Gokhan Zengin. (2022) Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent. Environmental Science and Pollution Research 29:21, pages 31025-31041.
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Dwight L. McKee & Mamoona S. Lodhi. (2021) 43 Natural Anticancer Products: Classified under the Cancer Hallmarks and the Available Evidence of their Anticancer Activities. Journal of Cancer Research Updates 10, pages 56-81.
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Marta Di Martile, Stefania Garzoli, Manuela Sabatino, Elisabetta Valentini, Simona D’Aguanno, Rino Ragno & Donatella Del Bufalo. (2021) Antitumor effect of Melaleuca alternifolia essential oil and its main component terpinen-4-ol in combination with target therapy in melanoma models. Cell Death Discovery 7:1.
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Yu Sawada & Motonobu Nakamura. (2021) Daily Lifestyle and Cutaneous Malignancies. International Journal of Molecular Sciences 22:10, pages 5227.
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Tommaso Iannitti, Alessandro Di Cerbo, Anna Rita Loschi, Stefano Rea, Michiko Suzawa & Julio César Morales‐Medina. (2020) Repeated administration of a flavonoid‐based formulated extract from citrus peels significantly reduces peripheral inflammation‐induced pain in the rat. Food Science & Nutrition 8:7, pages 3173-3180.
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Balwinder Singh, Jatinder Pal Singh, Amritpal Kaur & Narpinder Singh. (2020) Phenolic composition, antioxidant potential and health benefits of citrus peel. Food Research International 132, pages 109114.
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Nooshin Koolaji, Balakrishnan Shammugasamy, Aaron Schindeler, Qihan Dong, Fariba Dehghani & Peter Valtchev. (2020) Citrus Peel Flavonoids as Potential Cancer Prevention Agents. Current Developments in Nutrition 4:5, pages nzaa025.
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Julia Hoffmann, Fabian Gendrisch, Christoph Mathis Schempp & Ute Wölfle. (2020) New Herbal Biomedicines for the Topical Treatment of Dermatological Disorders. Biomedicines 8:2, pages 27.
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Sawsan G. Mohammed & M. Walid Qoronfleh. 2020. Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management. Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management 279 376 .
Nassim Zeinali, Ibukun Oluwoye, Mohammednoor K. Altarawneh, Mansour H. Almatarneh & Bogdan Z. Dlugogorski. (2019) Probing the Reactivity of Singlet Oxygen with Cyclic Monoterpenes. ACS Omega 4:9, pages 14040-14048.
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Sebastião Antonio Mendanha, Cássia Alessandra Marquezin, Amando Siuiti Ito & Antonio Alonso. (2017) Effects of nerolidol and limonene on stratum corneum membranes: A probe EPR and fluorescence spectroscopy study. International Journal of Pharmaceutics 532:1, pages 547-554.
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Tingting Zheng, Yueqiong Ni, Jun Li, Billy K. C. Chow & Gianni Panagiotou. (2017) Designing Dietary Recommendations Using System Level Interactomics Analysis and Network-Based Inference. Frontiers in Physiology 8.
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Ammad Ahmad Farooqi, Rubina Sohail, Sundas Fayyaz & Iryna Shatynska-Mytsyk. 2015. Bioactive Essential Oils and Cancer. Bioactive Essential Oils and Cancer 125 133 .
Shiming Li, Yi-Chin Lin, Chi-Tang Ho, Ping-Yi Lin, Michiko Suzawa, Hsin-Chieh Wang, Ching-Liang Chu, Der-Yuan Chen & Chi-Chen Lin. (2014) Formulated extract from multiple citrus peels impairs dendritic cell functions and attenuates allergic contact hypersensitivity. International Immunopharmacology 20:1, pages 12-23.
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Andrew C. Chen, Diona L. Damian & Gary M. Halliday. (2014) Oral and systemic photoprotection. Photodermatology, Photoimmunology & Photomedicine 30:2-3, pages 102-111.
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Shahla Shojaei, Amir Kiumarsi, Adel Rezaei Moghadam, Javad Alizadeh, Hassan Marzban & Saeid Ghavami. 2014. Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids. Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids 7 32 .
Andrew C. Chen, Gary M. Halliday & Diona L. Damian. (2013) Non-melanoma skin cancer: carcinogenesis and chemoprevention. Pathology 45:3, pages 331-341.
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SHU-SHENG JIA, GUANG-PENG XI, MING ZHANG, YAN-BO CHEN, BO LEI, XIN-SHU DONG & YAN-MEI YANG. (2012) Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells. Oncology Reports 29:1, pages 349-354.
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Ching-Shu Lai, Shiming Li, Yutaka Miyauchi, Michiko Suzawa, Chi-Tang Ho & Min-Hsiung Pan. (2013) Potent anti-cancer effects of citrus peel flavonoids in human prostate xenograft tumors. Food & Function 4:6, pages 944.
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Chelsea Lynn Carey & Ronald Ross Watson. 2013. Bioactive Dietary Factors and Plant Extracts in Dermatology. Bioactive Dietary Factors and Plant Extracts in Dermatology 277 282 .
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Ahmed N. Uddin, Ivica Labuda & Fredric J. Burns. (2012) A novel mechanism of filaggrin induction and sunburn prevention by β-damascenone in Skh-1 mice. Toxicology and Applied Pharmacology 265:3, pages 335-341.
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Hung-Chieh Lan, Ying Liang, Hsiu-Chuan Hsu, Jiah-Hwang Shu, Chien-Wei Su, Hung-Hsu Hung, Ming-Chih Hou, Han-Chieh Lin, Shou-Dong Lee & Yuan-Jen Wang. (2012) Citrus reticulata peel improves patient tolerance of low-volume polyethylene glycol for colonoscopy preparation. Journal of the Chinese Medical Association 75:9, pages 442-448.
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I. A. Jideani, T. Takalani, V. A. Jideani & Muhammad Siddiq. 2012. Tropical and Subtropical Fruits. Tropical and Subtropical Fruits 359 375 .
Yu-Chun Huang, Kao-Chih Liu & Yi-Ling Chiou. (2012) Melanogenesis of murine melanoma cells induced by hesperetin, a Citrus hydrolysate-derived flavonoid. Food and Chemical Toxicology 50:3-4, pages 653-659.
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Renata Prado, Shayla O. Francis, Mariah N. Mason, Gregory Wing, Ryan G. Gamble & Robert Dellavalle. (2011) Nonmelanoma Skin Cancer Chemoprevention. Dermatologic Surgery 37:11, pages 1566-1578.
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Jessica A. Miller, Patricia A. Thompson, Iman A. Hakim, H.-H. Sherry Chow & Cynthia A. Thomson. (2010) d-Limonene: a bioactive food component from citrus and evidence for a potential role in breast cancer prevention and treatment. Oncology Reviews 5:1, pages 31-42.
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S. J. Greay, D. J. Ireland, H. T. Kissick, A. Levy, M. W. Beilharz, T. V. Riley & C. F. Carson. (2009) Induction of necrosis and cell cycle arrest in murine cancer cell lines by Melaleuca alternifolia (tea tree) oil and terpinen-4-ol. Cancer Chemotherapy and Pharmacology 65:5, pages 877-888.
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Niva Shapira. (2010) Nutritional approach to sun protection: a suggested complement to external strategies. Nutrition Reviews 68:2, pages 75-86.
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Hamendra Singh Parmar & Anand Kar. (2009) Protective role of Mangifera indica, Cucumis melo and Citrullus vulgaris peel extracts in chemically induced hypothyroidism. Chemico-Biological Interactions 177:3, pages 254-258.
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Jessica A. Miller, Iman A. Hakim, Cynthia Thomson, Patricia Thompson & H.-H. Sherry Chow. (2008) Determination of d-limonene in adipose tissue by gas chromatography–mass spectrometry. Journal of Chromatography B 870:1, pages 68-73.
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Hamendra Singh Parmar & Anand Kar. (2008) Medicinal Values of Fruit Peels from Citrus sinensis , Punica granatum , and Musa paradisiaca with Respect to Alterations in Tissue Lipid Peroxidation and Serum Concentration of Glucose, Insulin, and Thyroid Hormones . Journal of Medicinal Food 11:2, pages 376-381.
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H. S. Parmar & A. Kar. (2008) Antiperoxidative, antithyroidal, antihyperglycemic and cardioprotective role of Citrus sinensis peel extract in male mice . Phytotherapy Research 22:6, pages 791-795.
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Hamendra Singh Parmar & Anand Kar. (2009) Possible amelioration of atherogenic diet induced dyslipidemia, hypothyroidism and hyperglycemia by the peel extracts of Mangifera indica, Cucumis melo and Citrullus vulgaris fruits in rats . BioFactors 33:1, pages 13-24.
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Hamendra Singh Parmar & Anand Kar. (2007) Protective role of Citrus sinensis, Musa paradisiaca, and Punica granatum peels against diet-induced atherosclerosis and thyroid dysfunctions in rats. Nutrition Research 27:11, pages 710-718.
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Kunhua FanNaoto KuriharaSadanori AbeChi-Tang HoGeetha GhaiKan Yang. (2007) Chemopreventive Effects of Orange Peel Extract (OPE) I. OPE Inhibits Intestinal Tumor Growth in Apc Min/+ Mice . Journal of Medicinal Food 10:1, pages 11-17.
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Hamendra Singh Parmar & Anand Kar. (2007) Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice . BioFactors 31:1, pages 17-24.
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