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Original Articles

Most Effective Colon Cancer Chemopreventive Agents in Rats: A Systematic Review of Aberrant Crypt Foci and Tumor Data, Ranked by Potency

Pages 1-21 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Ahmet Uyar, Abdulahad Doğan, Turan Yaman, Ömer Faruk Keleş, Zabit Yener, İsmail Çelik & Elif Ebru Alkan. (2022) The Protective Role of Urtica dioica Seed Extract Against Azoxymethane-Induced Colon Carcinogenesis in Rats. Nutrition and Cancer 74:1, pages 306-319.
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Lin Zhou, Muhammad Zahid, Muhammad M. Anwar, Karen L. Pennington, Samuel M. Cohen, James L. Wisecarver, Valerie Shostrom & Sidney S. Mirvish. (2016) Suggestive evidence for the induction of colonic aberrant crypts in mice fed sodium nitrite. Nutrition and Cancer 68:1, pages 105-112.
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Vigneshwaran Ramanathan, Guangchun Jin, Christoph Benedikt Westphalen, Ashley Whelan, Alexander Dubeykovskiy, Shigeo Takaishi & Timothy C. Wang. (2012) P53 Gene Mutation Increases Progastrin Dependent Colonic Proliferation and Colon Cancer Formation in Mice. Cancer Investigation 30:4, pages 275-286.
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MichaelE. Davis, MichalP. Lisowyj, Lin Zhou, JamesL. Wisecarver, JamesM. Gulizia, ValerieK. Shostrom, Nathalie Naud, DenisE. Corpet & SidneyS. Mirvish. (2012) Induction of Colonic Aberrant Crypts in Mice by Feeding Apparent N-Nitroso Compounds Derived From Hot Dogs. Nutrition and Cancer 64:2, pages 342-349.
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Morten Poulsen, Alicja Mortensen, Mona-Lise Binderup, Søren Langkilde, Jaroslaw Markowski & Lars Ove Dragsted. (2011) The Effect of Apple Feeding on Markers of Colon Carcinogenesis. Nutrition and Cancer 63:3, pages 402-409.
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Patricia A Thompson & Eugene W Gerner. (2009) Current concepts in colorectal cancer prevention. Expert Review of Gastroenterology & Hepatology 3:4, pages 369-382.
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Liane Ziliotto, Fabriciano Pinheiro, Luís Fernando Barbisan & Maria Aparecida Marchesan Rodrigues. (2009) Screening for In Vitro and In Vivo Antitumor Activities of the Mushroom Agaricus Blazei . Nutrition and Cancer 61:2, pages 245-250.
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Giovanna Ribeiro-Santos, Luís Fernando Barbisan, Fabiane Catanho Lopes, Ana Lúcia Tozzi Spinardi-Barbisan, Augusto Ferreira da Eira & Ramon Kaneno. (2008) Lack of Chemopreventive Activity of Agaricus blazei Mushroom on the Development of 1,2-Dimethylhydrazine-Induced Colonic Aberrant Crypt Foci in Rats. Nutrition and Cancer 60:6, pages 768-775.
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Genoveva Murillo, WendyH. Hirschelman, Aiko Ito, RobertM. Moriarty, A. Douglas Kinghorn, JohnM. Pezzuto & RajendraG. Mehta. (2007) Zapotin, a Phytochemical Present in a Mexican Fruit, Prevents Colon Carcinogenesis. Nutrition and Cancer 57:1, pages 28-37.
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Despina Komninou, Yvonne Leutzinger, Bandaru S. Reddy & John P. Richie Jr.. (2006) Methionine Restriction Inhibits Colon Carcinogenesis. Nutrition and Cancer 54:2, pages 202-208.
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Angela Au, Boyong Li, Weiqun Wang, Hemant Roy, Ken Koehler & Diane Birt. (2006) Effect of Dietary Apigenin on Colonic Ornithine Decarboxylase Activity, Aberrant Crypt Foci Formation, and Tumorigenesis in Different Experimental Models. Nutrition and Cancer 54:2, pages 243-251.
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Geeta Lala, Minnie Malik, Cuiwei Zhao, Jian He, Youngjoo Kwon, M. Monica Giusti & Bernadene A. Magnuson. (2006) Anthocyanin-Rich Extracts Inhibit Multiple Biomarkers of Colon Cancer in Rats. Nutrition and Cancer 54:1, pages 84-93.
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Regina Brigelius-Flohé & Antje Banning. (2006) Part of the Series: From dietary antioxidants to regulators in cellular signaling and gene regulation. Free Radical Research 40:8, pages 775-787.
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Sylviane Taché, Géraldine Parnaud, Erik Van Beek & Denis E. Corpet. (2006) Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells. Scandinavian Journal of Gastroenterology 41:6, pages 730-736.
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Chandra Kirana, Graeme H. McIntosh, Ian R. Record & Graham P. Jones. (2003) Antitumor Activity of Extract of Zingiber aromaticum and Its Bioactive Sesquiterpenoid Zerumbone. Nutrition and Cancer 45:2, pages 218-225.
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