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Original Articles

Protection by Quercetin Against Cooking Oil Fumes-Induced DNA Damage in Human Lung Adenocarcinoma CL-3 Cells: Role of COX-2

Pages 95-101 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Huey-Shan Hung, Wen-Jun Wu, Ya-Wen Cheng, Ming-Fan Wu, Kee-Lung Chang & Huei Lee. (2005) Cooking Oil Fumes Improve Lung Adenocarcinoma Cell Survival Through c-IAP2 Induction. Journal of Toxicology and Environmental Health, Part A 68:17-18, pages 1525-1535.
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Anna Maciag & Lucy M. Anderson. (2004) Reactive Oxygen Species And Lung Tumorigenesis By Mutant K-: A Working Hypothesis. Experimental Lung Research 31:1, pages 83-104.
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Ya Wen Cheng & Huei Lee. (2003) Environmental Exposure and Lung Cancer Among Nonsmokers: An Example of Taiwanese Female Lung Cancer. Journal of Environmental Science and Health, Part C 21:1, pages 1-28.
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Articles from other publishers (24)

Mukta Gupta, Javed Ahmad, Javed Ahamad, Snehashis Kundu, Archit Goel & Awanish Mishra. (2023) Flavonoids as promising anticancer therapeutics: Contemporary research, nanoantioxidant potential, and future scope. Phytotherapy Research 37:11, pages 5159-5192.
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Hasan Slika, Hadi Mansour, Nadine Wehbe, Suzanne A. Nasser, Rabah Iratni, Gheyath Nasrallah, Abdullah Shaito, Tarek Ghaddar, Firas Kobeissy & Ali H. Eid. (2022) Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms. Biomedicine & Pharmacotherapy 146, pages 112442.
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Arunaksharan Narayanankutty, Anu Anil, Soorya Parathodi Illam, Sruthi Panniyan Kandiyil & Achuthan C. Raghavamenon. (2018) Non-polar lipid carbonyls of thermally oxidized coconut oil induce hepatotoxicity mediated by redox imbalance. Prostaglandins, Leukotrienes and Essential Fatty Acids 138, pages 45-51.
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Payal Mandal, Ankita Rai, Sakshi Mishra, Anurag Tripathi & Mukul Das. 2018. Mutagenicity: Assays and Applications. Mutagenicity: Assays and Applications 133 160 .
Mosaad A. Abdel-Wahhab, Abdulhadi Aljawish, Aziza A. El-Nekeety, Sekena H. Abdel-Aziem & Nabila S. Hassan. (2017) Chitosan nanoparticles plus quercetin suppress the oxidative stress, modulate DNA fragmentation and gene expression in the kidney of rats fed ochratoxin A-contaminated diet. Food and Chemical Toxicology 99, pages 209-221.
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Nagendra Sastry Yarla, Anupam Bishayee, Gautam Sethi, Pallu Reddanna, Arunasree M. Kalle, Bhadrapura Lakkappa Dhananjaya, Kaladhar S.V.G.K. Dowluru, Ramakrishna Chintala & Govinda Rao Duddukuri. (2016) Targeting arachidonic acid pathway by natural products for cancer prevention and therapy. Seminars in Cancer Biology 40-41, pages 48-81.
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Abdur Rauf, Rehan Khan, Muslim Raza, Haroon Khan, Samreen Pervez, Vincenzo De Feo, Francesco Maione & Nicola Mascolo. (2015) Suppression of inflammatory response by chrysin, a flavone isolated from Potentilla evestita Th. Wolf. In silico predictive study on its mechanistic effect. Fitoterapia 103, pages 129-135.
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Chung-Ming Lin, Wei-Chien Kao, Chun-An Yeh, Hui-Jye Chen, Shinn-Zong Lin, Hsien-Hsu Hsieh, Wei-Shen Sun, Chih-Hsuan Chang & Huey-Shan Hung. (2015) Hyaluronic acid-fabricated nanogold delivery of the inhibitor of apoptosis protein-2 siRNAs inhibits benzo[ a ]pyrene-induced oncogenic properties of lung cancer A549 cells . Nanotechnology 26:10, pages 105101.
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João Lago, Alessandra Toledo-Arruda, Márcia Mernak, Kaidu Barrosa, Milton Martins, Iolanda Tibério & Carla Prado. (2014) Structure-Activity Association of Flavonoids in Lung Diseases. Molecules 19:3, pages 3570-3595.
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Periasamy Ramyaa, Rajashree krishnaswamy & Viswanadha Vijaya Padma. (2014) Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells — up regulation of Nrf2 expression and down regulation of NF-κB and COX-2. Biochimica et Biophysica Acta (BBA) - General Subjects 1840:1, pages 681-692.
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Min-Che Tung, Heng-Hsiung Wu, Ya-Wen Cheng, Lee Wang, Chih-Yi Chen, Sauh-Der Yeh, Tzu-Chin Wu & Huei Lee. (2013) Association of epidermal growth factor receptor mutations with human papillomavirus 16/18 E6 oncoprotein expression in non-small cell lung cancer. Cancer 119:18, pages 3367-3376.
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Trevor Lee & Francesca Gany. (2012) Cooking Oil Fumes and Lung Cancer: A Review of the Literature in the Context of the U.S. Population. Journal of Immigrant and Minority Health 15:3, pages 646-652.
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Yao Chen, Peng Xiao, Dong-Sheng Ou-Yang, Lan Fan, Dong Guo, Yi-Nan Wang, Yang Han, Jiang-Hua Tu, Gan Zhou, Yuan-Fei Huang & Hong-Hao Zhou. (2009) SIMULTANEOUS ACTION OF THE FLAVONOID QUERCETIN ON CYTOCHROME P450 (CYP) 1A2, CYP2A6, N -ACETYLTRANSFERASE AND XANTHINE OXIDASE ACTIVITY IN HEALTHY VOLUNTEERS . Clinical and Experimental Pharmacology and Physiology 36:8, pages 828-833.
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Jie Yang, Lu Wang, Zhaoli Chen, Zhi-Qiang Shen, Min Jin, Xin-Wei Wang, Yufei Zheng, Zhi-Gang Qiu, Jing-feng Wang & Jun-Wen Li. (2008) Antioxidant intervention of smoking-induced lung tumor in mice by vitamin E and quercetin. BMC Cancer 8:1.
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Lorne J. Hofseth. (2008) Nitric oxide as a target of complementary and alternative medicines to prevent and treat inflammation and cancer. Cancer Letters 268:1, pages 10-30.
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Huey-Shan Hung, Wen-Jun Wu, Ya-Wen Cheng, Tsu-Chin Wu, Kee-Lung Chang & Huei Lee. (2007) Association of cooking oil fumes exposure with lung cancer: Involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 628:2, pages 107-116.
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M. Kampa, A.-P. Nifli, G. Notas & E. Castanas. 2007. Reviews of Physiology, Biochemistry and Pharmacology. Reviews of Physiology, Biochemistry and Pharmacology 79 113 .
Nian-zu Jin, Yan-ping Zhu, Jian-wei Zhou, Li Mao, Ren-cheng Zhao, Tai-hui Fang & Xin-ru Wang. (2006) Preventive Effects of Quercetin against Benzo[a]pyrene-Induced DNA Damages and Pulmonary Precancerous Pathologic Changes in Mice. Basic <html_ent glyph="@amp;" ascii="&"/> Clinical Pharmacology <html_ent glyph="@amp;" ascii="&"/> Toxicology 98:6, pages 593-598.
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Shu-Lan Yeh, Wei-Yu Wang, Chin-Shiu Huang & Miao-Lin Hu. (2006) Flavonoids suppresses the enhancing effect of β-carotene on DNA damage induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A549 cells. Chemico-Biological Interactions 160:2, pages 175-182.
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Ki Won Lee & Hyong Joo Lee. (2006) The roles of polyphenols in cancer chemoprevention. BioFactors 26:2, pages 105-121.
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Shu-Lan Yeh, Wei-Yu Wang, Chin-Hsiu Huang & Miao-Lin Hu. (2005) Pro-oxidative effect of β-carotene and the interaction with flavonoids on UVA-induced DNA strand breaks in mouse fibroblast C3H10T1/2 cells. The Journal of Nutritional Biochemistry 16:12, pages 729-735.
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M.A. Soobrattee, V.S. Neergheen, A. Luximon-Ramma, O.I. Aruoma & T. Bahorun. (2005) Phenolics as potential antioxidant therapeutic agents: Mechanism and actions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 579:1-2, pages 200-213.
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Young-Joon Surh, Hye-Kyung Na & Hyong Joo Lee. 2004. Phytopharmaceuticals in Cancer Chemoprevention. Phytopharmaceuticals in Cancer Chemoprevention.
Karen A O’Leary, Sonia de Pascual-Tereasa, Paul W Needs, Yong-Ping Bao, Nora M O’Brien & Gary Williamson. (2004) Effect of flavonoids and Vitamin E on cyclooxygenase-2 (COX-2) transcription. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 551:1-2, pages 245-254.
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