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Original Articles

Effect of Red Clover Isoflavones on Cox-2 Activity in Murine and Human Monocyte/Macrophage Cells

Pages 89-93 | Published online: 18 Nov 2009

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Dicle Çevik, Basak Aru, Sanem Karagoz, Niyazi Gurizi & Ozlem Demirkiran. (2023) Isolation and characterisation of secondary metabolites from Trifolium vesiculosum Savi and their antiproliferative activities. Natural Product Research 0:0, pages 1-9.
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Laurence Guy Howes, Michael John James, Timothy Florin & Catherine Walker. (2007) NV-52. Expert Opinion on Investigational Drugs 16:8, pages 1255-1266.
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Vadivelan Ramachandran, Inba Kumar V, Kiran Kumar hr, Ruchi Tiwari & Gaurav Tiwari. (2022) Biochanin-A: A Bioactive Natural Product with Versatile Therapeutic Perspectives. Current Drug Research Reviews 14:3, pages 225-238.
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Nattinee Jantaratnotai, Anusorn Thampithak, Pongsak Utaisincharoen, Darawan Pinthong & Pimtip Sanvarinda. (2022) Inhibition of LPS-Induced Microglial Activation by the Ethyl Acetate Extract of Pueraria mirifica. International Journal of Environmental Research and Public Health 19:19, pages 12920.
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Wafaa A. Aboukamar, Abeer A. Elhenawy, Manar S. Elmehankar, Manal A. Elzoheiry, Randa El-Gamal, Lamiaa M. Elabbasy, Heba Hany & Nairmen Nabih. (2022) Activity of isoflavone biochanin A in chronic experimental toxoplasmosis: impact on inflammation. Parasitology Research 121:8, pages 2405-2414.
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Franciel Batista Felix, Juliana Priscila Vago, Débora de Oliveira Fernandes, Débora Gonzaga Martins, Isabella Zaidan Moreira, William Antonio Gonçalves, Walyson Coelho Costa, Jessica Maria Dantas Araújo, Celso Martins Queiroz-Junior, Gabriel Henrique Campolina-Silva, Frederico Marianetti Soriani, Lirlândia Pires Sousa, Renata Grespan, Mauro Martins Teixeira & Vanessa Pinho. (2021) Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism. Frontiers in Pharmacology 12.
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Liyu Luo, Wenya Gao, Yan Zhang, Chang Liu, Guopeng Wang, Hongwei Wu & Wenyuan Gao. (2020) Integrated Phytochemical Analysis Based on UPLC-MS and Network Pharmacology Approaches to Explore the Quality Control Markers for the Quality Assessment of Trifolium pratense L.. Molecules 25:17, pages 3787.
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Chen Yu, Peng Zhang, Lixin Lou & Yang Wang. (2019) Perspectives Regarding the Role of Biochanin A in Humans. Frontiers in Pharmacology 10.
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Joanna Kolodziejczyk-Czepas, Barbara Wachowicz, Barbara Moniuszko-Szajwaj, Iwona Kowalska, Wieslaw Oleszek & Anna Stochmal. (2013) Antioxidative effects of extracts from Trifolium species on blood platelets exposed to oxidative stress. Journal of Physiology and Biochemistry 69:4, pages 879-887.
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Tae-Gyu Lim, Jong-Eun Kim, Sung Keun Jung, Yan Li, Ann M. Bode, Jun-Seong Park, Myeong Hun Yeom, Zigang Dong & Ki Won Lee. (2013) MLK3 is a direct target of biochanin A, which plays a role in solar UV-induced COX-2 expression in human keratinocytes. Biochemical Pharmacology 86:7, pages 896-903.
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Joanna Kolodziejczyk-Czepas. (2012) Trifolium species-derived substances and extracts—Biological activity and prospects for medicinal applications. Journal of Ethnopharmacology 143:1, pages 14-23.
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Sunil Kumar Manna. (2012) Double-edged sword effect of biochanin to inhibit nuclear factor kappaB: Suppression of serine/threonine and tyrosine kinases. Biochemical Pharmacology 83:10, pages 1383-1392.
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Labanyamoy Kole, Biplab Giri, Sunil Kumar Manna, Biswajit Pal & Sajalendu Ghosh. (2011) Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocation. European Journal of Pharmacology 653:1-3, pages 8-15.
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L Thors, JJ Burston, BJ Alter, MK McKinney, BF Cravatt, RA Ross, RG Pertwee, RW Gereau 4th, JL Wiley & CJ Fowler. (2010) Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. British Journal of Pharmacology 160:3, pages 549-560.
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Monika Mueller, Stefanie Hobiger & Alois Jungbauer. (2010) Red clover extract. Menopause 17:2, pages 379-387.
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