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Original Articles

Conjugated Linoleic Acid Inhibits Proliferation and Modulates Protein Kinase C Isoforms in Human Prostate Cancer Cells

Pages 100-108 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Alireza Poustforoosh, Sanaz Faramarz, Manica Negahdaripour, Burak Tüzün & Hassan Hashemipour. (2023) Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-14.
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LynnS. Adams, Shiuan Chen, Sheryl Phung, Xiwei Wu & Lui Ki. (2008) White Button Mushroom (Agaricus Bisporus) Exhibits Antiproliferative and Proapoptotic Properties and Inhibits Prostate Tumor Growth in Athymic Mice. Nutrition and Cancer 60:6, pages 744-756.
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StephanieC. Degner, MichaelQ. Kemp, JenniferK. Hockings & DonatoF. Romagnolo. (2007) Cyclooxygenase-2 Promoter Activation by the Aromatic Hydrocarbon Receptor in Breast Cancer MCF-7 Cells: Repressive Effects of Conjugated Linoleic Acid. Nutrition and Cancer 59:2, pages 248-257.
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Articles from other publishers (25)

Azadeh Yeganeh, Carla G. Taylor, Leslee Tworek, Jenna Poole & Peter Zahradka. (2016) Trans -10, cis -12 conjugated linoleic acid (CLA) interferes with lipid droplet accumulation during 3T3-L1 preadipocyte differentiation. The International Journal of Biochemistry & Cell Biology 76, pages 39-50.
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Miao Liu, Tarek Boussetta, Karama Makni-Maalej, Michèle Fay, Fathi Driss, Jamel El-Benna, Michel Lagarde & Michel Guichardant. (2013) Protectin DX, a Double Lipoxygenase Product of DHA, Inhibits Both ROS Production in Human Neutrophils and Cyclooxygenase Activities. Lipids 49:1, pages 49-57.
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H.-J. Song, A.A. Sneddon, S.D. Heys & K.W.J. Wahle. (2012) Regulation of fatty acid synthase (FAS) and apoptosis in estrogen-receptor positive and negative breast cancer cells by conjugated linoleic acids. Prostaglandins, Leukotrienes and Essential Fatty Acids 87:6, pages 197-203.
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Hsin-Hsin Kao, Chao-Jung Wu, Shen-Jeu Won, Jyh-Wei Shin, Hsiao-Sheng Liu & Chun-Li Su. (2011) Kinase Gene Expression and Subcellular Protein Expression Pattern of Protein Kinase C Isoforms in Curcumin-treated Human Hepatocellular Carcinoma Hep 3B Cells. Plant Foods for Human Nutrition 66:2, pages 136-142.
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Yeonhwa Park. (2009) Conjugated linoleic acid (CLA): Good or bad trans fat?. Journal of Food Composition and Analysis 22, pages S4-S12.
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Yaron R Silberberg, Gleb E Yakubov, Michael A Horton & Andrew E Pelling. (2009) Cell nanomechanics and focal adhesions are regulated by retinol and conjugated linoleic acid in a dose-dependent manner. Nanotechnology 20:28, pages 285103.
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Sunjin Hur, Faith Whitcomb, Siyeon Rhee, Yooheon Park, Deborah J. Good & Yeonhwa Park. (2009) Effects of trans -10, cis -12 Conjugated Linoleic Acid on Body Composition in Genetically Obese Mice . Journal of Medicinal Food 12:1, pages 56-63.
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Angela M. Sikorski, Nathan Hebert & Rodney A. Swain. (2008) Conjugated Linoleic Acid (CLA) inhibits new vessel growth in the mammalian brain. Brain Research 1213, pages 35-40.
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M. Goua, S. Mulgrew, J. Frank, D. Rees, A.A. Sneddon & K.W.J. Wahle. (2008) Regulation of adhesion molecule expression in human endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids: Involvement of the transcription factor NF-κB?. Prostaglandins, Leukotrienes and Essential Fatty Acids 78:1, pages 33-43.
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Klaus W.J. Wahle, Marie Goua, Simona D'Urso & Steven D. Heys. 2008. Trans Fatty Acids. Trans Fatty Acids 54 101 .
Y. Park, K.J. Albright, J.M. Storkson, W. Liu & M.W. Pariza. (2007) Conjugated Linoleic Acid (CLA) Prevents Body Fat Accumulation and Weight Gain in an Animal Model. Journal of Food Science 72:8, pages S612-S617.
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Alemu Fite, Marie Goua, Klaus W.J. Wahle, Andrew C. Schofield, Andrew W. Hutcheon & Steven D. Heys. (2007) Potentiation of the anti-tumour effect of docetaxel by conjugated linoleic acids (CLAs) in breast cancer cells in vitro. Prostaglandins, Leukotrienes and Essential Fatty Acids 77:2, pages 87-96.
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Sun Jin Hur & Yeonhwa Park. (2007) Effect of conjugated linoleic acid on bone formation and rheumatoid arthritis. European Journal of Pharmacology 568:1-3, pages 16-24.
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YEONHWA PARK, MINGDER YANG, JAYNE M. STORKSON, KAREN J. ALBRIGHT, WEI LIU, MARK E. COOK & MICHAEL W. PARIZA. (2007) EFFECTS OF CONJUGATED LINOLEIC ACID ISOMERS ON SERUM TUMOR NECROSIS FACTOR-A CONCENTRATION IN MICE. Journal of Food Biochemistry 31:2, pages 252-265.
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Yeonhwa Park & Michael W. Pariza. (2007) Mechanisms of body fat modulation by conjugated linoleic acid (CLA). Food Research International 40:3, pages 311-323.
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Gregory Miller, Judith Jarvis & Lois McBean. 2006. Handbook of Dairy Foods and Nutrition, Third Edition. Handbook of Dairy Foods and Nutrition, Third Edition 141 179 .
Arunabh Bhattacharya, Jameela Banu, Mizanur Rahman, Jennifer Causey & Gabriel Fernandes. (2006) Biological effects of conjugated linoleic acids in health and disease. The Journal of Nutritional Biochemistry 17:12, pages 789-810.
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Bruce Watkins & Yong Li. 2006. Handbook of Nutraceuticals and Functional Foods, Second Edition. Handbook of Nutraceuticals and Functional Foods, Second Edition 285 295 .
Eun Ji KimHyun-Kyung ShinJin Sun ChoSang Kon LeeMoo Ho WonJong Woo KimJung Han Yoon Park. (2006) trans -10, cis -12 Conjugated Linoleic Acid Inhibits the G1–S Cell Cycle Progression in DU145 Human Prostate Carcinoma Cells . Journal of Medicinal Food 9:3, pages 293-299.
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Hyun‐Ju Song, Alan A. Sneddon, Steven D. Heys & Klaus W.J. Wahle. (2006) Induction of apoptosis and inhibition of NF‐κB activation in human prostate cancer cells by the cis ‐9, trans ‐11 but not the trans ‐10, cis‐ 12 isomer of conjugated linoleic acid . The Prostate 66:8, pages 839-846.
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Antonella Miglietta, Francesca Bozzo, Claudia Bocca, Ludovica Gabriel, Antonella Trombetta, Simona Belotti & Rosa A. Canuto. (2006) Conjugated linoleic acid induces apoptosis in MDA-MB-231 breast cancer cells through ERK/MAPK signalling and mitochondrial pathway. Cancer Letters 234:2, pages 149-157.
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Paramjit S. TappiaRabban MangatCindy GabrielMelissa R. DentNina AroutiounovaHope Weiler. (2006) Gender differences in the cardiac response to dietary conjugated linoleic acid isomers. Canadian Journal of Physiology and Pharmacology 84:2, pages 257-264.
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Stephanie C Degner, Michael Q Kemp, G. Tim Bowden & Donato F Romagnolo. (2006) Conjugated Linoleic Acid Attenuates Cyclooxygenase-2 Transcriptional Activity via an Anti-AP-1 Mechanism in MCF-7 Breast Cancer Cells. The Journal of Nutrition 136:2, pages 421-427.
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Masao Yamasaki, Yumi Miyamoto, Hitomi Chujo, Kazuo Nishiyama, Hirofumi Tachibana & Koji Yamada. (2005) Trans10, cis12-conjugated linoleic acid induces mitochondria-related apoptosis and lysosomal destabilization in rat hepatoma cells. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1735:3, pages 176-184.
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Klaus W.J. Wahle, Steven D. Heys & Dino Rotondo. (2004) Conjugated linoleic acids: are they beneficial or detrimental to health?. Progress in Lipid Research 43:6, pages 553-587.
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