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Original Articles

Phytoestrogens in Common Herbs Regulate Prostate Cancer Cell Growth in Vitro

Pages 200-208 | Published online: 18 Nov 2009

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Katrin Sak. (2014) Site-Specific Anticancer Effects of Dietary Flavonoid Quercetin. Nutrition and Cancer 66:2, pages 177-193.
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Piwen Wang, David Heber & SusanneM. Henning. (2012) Quercetin Increased the Antiproliferative Activity of Green Tea Polyphenol (-)-Epigallocatechin Gallate in Prostate Cancer Cells. Nutrition and Cancer 64:4, pages 580-587.
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Articles from other publishers (73)

Hans Van der Eecken, Steven Joniau, Charlien Berghen, Kato Rans & Gert De Meerleer. (2023) The Use of Soy Isoflavones in the Treatment of Prostate Cancer: A Focus on the Cellular Effects. Nutrients 15:23, pages 4856.
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Tomislav Pejčić, Milica Zeković, Uroš Bumbaširević, Milica Kalaba, Irena Vovk, Maja Bensa, Lazar Popović & Živoslav Tešić. (2023) The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer. Antioxidants 12:2, pages 368.
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Aleksandra Golonko, Adam Jan Olichwier, Renata Swislocka, Lukasz Szczerbinski & Włodzimierz Lewandowski. (2022) Why Do Dietary Flavonoids Have a Promising Effect as Enhancers of Anthracyclines? Hydroxyl Substituents, Bioavailability and Biological Activity. International Journal of Molecular Sciences 24:1, pages 391.
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Rafael Abe da Rocha Miranda, Marcela Martins de Paula Oliveira, Maria Isadora Gabriel Sampaio, João Victor Dutra Gomes, Damaris Silveira, Eliete Neves Silva Guerra, Adriana Lofrano‐Porto, Cinthia Gabriel Meireles & Luiz Alberto Simeoni. (2022) Effects of medicinal plants and natural compounds in models of prostate cancer related to sex steroids: A systematic review. Phytotherapy Research 36:8, pages 3032-3079.
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Shenglin Hou. (2022) Genistein: Therapeutic and Preventive Effects, Mechanisms, and Clinical Application in Digestive Tract Tumor. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-10.
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Ludwika Piwowarczyk, Malgorzata Kucinska, Szymon Tomczak, Dariusz T. Mlynarczyk, Jaroslaw Piskorz, Tomasz Goslinski, Marek Murias & Anna Jelinska. (2022) Liposomal Nanoformulation as a Carrier for Curcumin and pEGCG—Study on Stability and Anticancer Potential. Nanomaterials 12:8, pages 1274.
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Loveleen Sarao, Sandeep Kaur, Tanu Malik & Ajay Singh. 2022. Nutraceuticals and Health Care. Nutraceuticals and Health Care 331 341 .
Noha Fawzy Abdelkader & Passant Elwy Moustafa. 2022. Plants and Phytomolecules for Immunomodulation. Plants and Phytomolecules for Immunomodulation 361 390 .
Norlia Abdullah & Norazlina Mohamed. (2021) Influence of cultural practices on breast cancer risks, stage at presentation and outcome in a multi‑ethnic developing country (Review). Oncology Letters 22:5.
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Linda Bechnak, Christian Khalil, Riham El Kurdi, Rony S. Khnayzer & Digambara Patra. (2020) Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules: colloidal nanocapsules enhance photodynamic and anticancer activities of curcumin. Photochemical & Photobiological Sciences 19:8, pages 1088-1098.
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Nurul Azwa Abd. Wahab, Nordin H. Lajis, Faridah Abas, Iekhsan Othman & Rakesh Naidu. (2020) Mechanism of Anti-Cancer Activity of Curcumin on Androgen-Dependent and Androgen-Independent Prostate Cancer. Nutrients 12:3, pages 679.
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Pravien Rajaram, Ziran Jiang, Guanglin Chen, Alyssa Rivera, Alison Phasakda, Qiang Zhang, Shilong Zheng, Guangdi Wang & Qiao-Hong Chen. (2019) Nitrogen-containing derivatives of O-tetramethylquercetin: Synthesis and biological profiles in prostate cancer cell models. Bioorganic Chemistry 87, pages 227-239.
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Subhendu Chakrabarty, Debasish Nag, Arnab Ganguli, Amlan Das, Debabrata Ghosh Dastidar & Gopal Chakrabarti. (2018) Theaflavin and epigallocatechin‐3‐gallate synergistically induce apoptosis through inhibition of PI3K/Akt signaling upon depolymerizing microtubules in HeLa cells. Journal of Cellular Biochemistry 120:4, pages 5987-6003.
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Mehmet Rıfkı TOPÇUL. (2019) Evaluation of Kinetic Effects of Baicalein in Different Breast Cancer Cell LinesBaicalein’in Farklı Meme Kanseri Hücre hatlarındaki Kinetik Etkilerinin Değerlendirilmesi. Cumhuriyet Science Journal 40:1, pages 150-157.
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Yan Chen, Duan-Yang Hong, Jing Wang, Jun Ling-Hu, Yan-Yan Zhang, Di Pan, Yi-Ni Xu, Ling Tao, Hong Luo & Xiang-Chun Shen. (2017) Baicalein, unlike 4-hydroxytamoxifen but similar to G15, suppresses 17β-estradiol-induced cell invasion, and matrix metalloproteinase-9 expression and activation in MCF-7 human breast cancer cells. Oncology Letters 14:2, pages 1823-1830.
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Qiang Zhang, Guangdong Cheng, Hongbin Qiu, Yuexin Wang, Jingtao Wang, Hui Xu, Tao Zhang, Lixin Liu, Ye Tao & Zhongjuan Ren. (2017) Expression of prostate stem cell antigen is downregulated during flavonoid-induced cytotoxicity in prostate cancer cells. Experimental and Therapeutic Medicine 14:2, pages 1795-1801.
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Yan Chen, Jing Wang, Duan-Yang Hong, Lin Chen, Yan-Yan Zhang, Yi-Ni Xu, Di Pan, Ling-Yun Fu, Ling Tao, Hong Luo & Xiang-Chun Shen. (2017) Baicalein has protective effects on the 17β-estradiol-induced transformation of breast epithelial cells. Oncotarget 8:6, pages 10470-10484.
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Sami M.R. Al-Jabban, Xiaojie Zhang, Guanglin Chen, Ermias Addo Mekuria, Liva Harinantenaina Rakotondraibe & Qiao-Hong Chen. (2015) Synthesis and Anti-Proliferative Effects of Quercetin Derivatives. Natural Product Communications 10:12, pages 1934578X1501001.
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Qiao-Hong Chen, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias Addo Mekuria & Liva Harinantenaina Rakotondraibe. (2015) A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: Design, synthesis, and anti-proliferative evaluation. Bioorganic & Medicinal Chemistry Letters 25:20, pages 4553-4556.
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FEIYA YANG, LIMING SONG, HUIPING WANG, JUN WANG, ZHIQING XU & NIANZENG XING. (2015) Quercetin in prostate cancer: Chemotherapeutic and chemopreventive effects, mechanisms and clinical application potential (Review). Oncology Reports 33:6, pages 2659-2668.
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DANDAN SHANG, ZHENG LI, ZHUXIA ZHU, HUAMEI CHEN, LUJUN ZHAO, XUDONG WANG & YAN CHEN. (2015) Baicalein suppresses 17-β-estradiol-induced migration, adhesion and invasion of breast cancer cells via the G protein-coupled receptor 30 signaling pathway. Oncology Reports 33:4, pages 2077-2085.
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Rosa Moo-Puc, Edgar Caamal-Fuentes, Sergio R. Peraza-Sánchez, Anna Slusarz, Glenn Jackson, Sara K. Drenkhahn & Dennis B. Lubahn. (2015) Antiproliferative and Antiestrogenic Activities of Bonediol an Alkyl Catechol from Bonellia macrocarpa . BioMed Research International 2015, pages 1-6.
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Pedro Gonzalez-Menendez, David Hevia, Aida Rodriguez-Garcia, Juan C. Mayo & Rosa M. Sainz. (2014) Regulation of GLUT Transporters by Flavonoids in Androgen-Sensitive and -Insensitive Prostate Cancer Cells. Endocrinology 155:9, pages 3238-3250.
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Ganna Chornokur & Nagi B. Kumar. (2013) Prostate cancer chemoprevention in men of African descent: current state of the art and opportunities for future research. Cancer Causes & Control 24:8, pages 1465-1480.
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Sabarinath Chandrasekharan, Balaji Bhaskar, Ramanathan Muthiah, Ambadiyil K. Chandrasekharan & Viraragavan Ramamurthy. (2013) Estrogenic effect of three substituted deoxybenzoins. Steroids 78:2, pages 147-155.
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J. Mani, S. Kumar, G.J. Dobos & A. Haferkamp. (2012) Aspekte der traditionellen indischen Medizin (Ayurveda) in der UrologieAspects of traditional Indian medicine (Ayurveda) in urology. Der Urologe 51:12, pages 1663-1673.
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Fanny Caputo, Rolando Vegliante & Lina Ghibelli. (2012) Redox modulation of the DNA damage response. Biochemical Pharmacology 84:10, pages 1292-1306.
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Johan Hartman, Anders Ström & Jan-Åke Gustafsson. (2012) Current concepts and significance of estrogen receptor β in prostate cancer. Steroids 77:12, pages 1262-1266.
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Linlin Zhang, Lei Li, Min Jiao, Dapeng Wu, Kaijie Wu, Xiang Li, Guodong Zhu, Lin Yang, Xinyang Wang, Jer-Tsong Hsieh & Dalin He. (2012) Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog–Gli1 pathway. Cancer Letters 323:1, pages 48-57.
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Anna Ślusarz, Glenn A. Jackson, J. Kevin Day, Nader S. Shenouda, Jennifer L. Bogener, Jim D. Browning, Kevin L. Fritsche, Ruth S. MacDonald, Cynthia L. Besch-Williford & Dennis B. Lubahn. (2012) Aggressive Prostate Cancer Is Prevented in ERαKO Mice and Stimulated in ERβKO TRAMP Mice. Endocrinology 153:9, pages 4160-4170.
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Caitlin J. Murphy, Huadong Tang, Edward A. Van Kirk, Youqing Shen & William J. Murdoch. (2012) Reproductive effects of a pegylated curcumin. Reproductive Toxicology 34:1, pages 120-124.
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Nakuleshwar Dut Jasuja, Jyoti Choudhary, Preeti Sharama, Nidhi Sharma & Suresh C. Joshi. (2012) A Review on Bioactive Compounds and Medicinal Uses of Commiphora mukul. Journal of Plant Sciences 7:4, pages 113-137.
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Shigeo Horie. (2012) Chemoprevention of Prostate Cancer: Soy Isoflavones and Curcumin. Korean Journal of Urology 53:10, pages 665.
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Jessica Bitencourt Emilio Mendes, Manoela Klüppel Riekes, Viviane Matoso de Oliveira, Milton Domingos Michel, Hellen Karine Stulzer, Najeh Maissar Khalil, Sônia Faria Zawadzki, Rubiana Mara Mainardes & Paulo Vitor Farago. (2012) PHBV/PCL Microparticles for Controlled Release of Resveratrol: Physicochemical Characterization, Antioxidant Potential, and Effect on Hemolysis of Human Erythrocytes. The Scientific World Journal 2012, pages 1-13.
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Dhanir Tailor & Rana P. Singh. 2012. Nutrition, Diet and Cancer. Nutrition, Diet and Cancer 585 622 .
Sharmila Shankar & Rakesh K. Srivastava. 2012. Nutrition, Diet and Cancer. Nutrition, Diet and Cancer 413 457 .
Mawussi Adjakly, Rémy Bosviel, Nadège Rabiau, Jean-Paul Boiteux, Yves-Jean Bignon, Laurent Guy & Dominique Bernard-Gallon. (2011) DNA methylation and soy phytoestrogens: quantitative study in DU-145 and PC-3 human prostate cancer cell lines. Epigenomics 3:6, pages 795-803.
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Natalia YU Anisimova, Mikhail V Kiselevsky, Andrey V Sosnov, Sergey V Sadovnikov, Ivan N Stankov & Andrei A Gakh. (2011) Trans-, cis-, and dihydro-resveratrol: a comparative study. Chemistry Central Journal 5:1.
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Mohammad R. Noori-Daloii, Majid Momeny, Mehdi Yousefi, Forough Golsaz Shirazi, Mehdi Yaseri, Nasrin Motamed, Nazanin Kazemialiakbar & Saeed Hashemi. (2010) Multifaceted preventive effects of single agent quercetin on a human prostate adenocarcinoma cell line (PC-3): implications for nutritional transcriptomics and multi-target therapy. Medical Oncology 28:4, pages 1395-1404.
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Janak KhatiwadaMartha VergheseShurrita DavisLeonard L. Williams. (2011) Green Tea, Phytic Acid, and Inositol in Combination Reduced the Incidence of Azoxymethane-Induced Colon Tumors in Fisher 344 Male Rats. Journal of Medicinal Food 14:11, pages 1313-1320.
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Jun YanAaron E. Katz. (2010) ProstaCaid Induces G2/M Cell Cycle Arrest and Apoptosis in Human and Mouse Androgen-Dependent and-Independent Prostate Cancer Cells. Integrative Cancer Therapies 9:2, pages 186-196.
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Nadège Rabiau, Myriam Kossaï, Martin Braud, Nasséra Chalabi, Samir Satih, Yves-Jean Bignon & Dominique J. Bernard-Gallon. (2010) Genistein and daidzein act on a panel of genes implicated in cell cycle and angiogenesis by Polymerase Chain Reaction arrays in human prostate cancer cell lines. Cancer Epidemiology 34:2, pages 200-206.
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Hea Young Oh, Jandi Leem, So Jung Yoon, Sun Yoon & Sung Joon Hong. (2010) Lipid raft cholesterol and genistein inhibit the cell viability of prostate cancer cells via the partial contribution of EGFR-Akt/p70S6k pathway and down-regulation of androgen receptor. Biochemical and Biophysical Research Communications 393:2, pages 319-324.
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