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Original Articles

Quality Evaluation of Commercial Extracts of Scutellaria baicalensis

Pages 217-222 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Mihael Cristin Ichim, Francesca Scotti & Anthony Booker. (2022) Quality evaluation of commercial herbal products using chemical methods. Critical Reviews in Food Science and Nutrition 0:0, pages 1-21.
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Shambhoo Sharan Tripathi, Raushan Kumar, Akalabya Bissoyi & Syed Ibrahim Rizvi. (2022) Baicalein maintains redox balance in experimental hyperlipidemic rats. Archives of Physiology and Biochemistry 128:5, pages 1156-1164.
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Hilal Bardakci, Ebru Türköz Acar & Hasan Kırmızıbekmez. (2019) Simultaneous quantification of six phenylethanoid glycosides in some Turkish Scutellaria species by a new HPLC-DAD method. Natural Product Research 33:14, pages 2116-2119.
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Xiaoliang Liu, Fei Ye, Josephine Wu, Brian How, Wei Li & David Y. Zhang. (2015) Signaling Proteins and Pathways Affected by Flavonoids in Leukemia Cells. Nutrition and Cancer 67:2, pages 238-249.
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Fei Ye, Yufang Che, Elizabeth McMillen, Justin Gorski, Douglas Brodman, Daisy Saw, Bo Jiang & DavidY. Zhang. (2009) The Effect of Scutellaria Baicalensis on the Signaling Network in Hepatocellular Carcinoma Cells. Nutrition and Cancer 61:4, pages 530-537.
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Fei Ye, Shiquan Jiang, Helen Volshonok, Josephine Wu & DavidY. Zhang. (2007) Molecular Mechanism of Anti-Prostate Cancer Activity of Scutellaria Baicalensis Extract. Nutrition and Cancer 57:1, pages 100-110.
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Articles from other publishers (26)

Mihael Cristin Ichim & Anthony Booker. (2021) Chemical Authentication of Botanical Ingredients: A Review of Commercial Herbal Products. Frontiers in Pharmacology 12.
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Minting Chen, Haitao Xiao, Baisen Chen, Zhaoxiang Bian & Hiu Yee Kwan. (2021) The advantages of using Scutellaria baicalensis and its flavonoids for the management of non-viral hepatocellular carcinoma. Journal of Functional Foods 78, pages 104389.
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Hee-Sung Chae, Rong Xu, Jae-Yeon Won, Young-Won Chin & Hyungshin Yim. (2019) Molecular Targets of Genistein and Its Related Flavonoids to Exert Anticancer Effects. International Journal of Molecular Sciences 20:10, pages 2420.
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Bo Yoon Choi, Jong Cheon Joo, Yeon Kyu Lee, Ik-Soon Jang, Soo Jung Park & Yoon Jung Park. (2017) Anti-cancer effect of Scutellaria baicalensis in combination with cisplatin in human ovarian cancer cell. BMC Complementary and Alternative Medicine 17:1.
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Bu-Yeo Kim, Kwang Hoon Song, Chi-Yeon Lim & Su-In Cho. (2017) Therapeutic properties of Scutellaria baicalensis in db/db mice evaluated using Connectivity Map and network pharmacology. Scientific Reports 7:1.
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Eok-Cheon Kim, Kiho Bae, Han Sung Kim, Yeong-Min Yoo, Michael Gelinsky & Tack-Joong Kim. (2016) Hot Water Extract of Scutellaria baicalensis Inhibits Migration, Invasion and Tube Formation in a Human Umbilical Vein Endothelial Cell Model and a Rat Aortic Ring Sprouting Model. Journal of Life Science 26:1, pages 91-100.
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Balázs Magda, Zoltán Márta, Tímea Imre, Bernadett Kalapos-Kovács, Imre Klebovich, Jenő Fekete & Pál T. Szabó. (2015) Unexpected retention behavior of baicalin: Hydrophilic interaction like properties of a reversed-phase column. Journal of Pharmaceutical and Biomedical Analysis 111, pages 119-125.
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Jin A Kim, Arulkumar Nagappan, Hyeon Soo Park, Venu Venkatarame Gowda Saralamma, Gyeong Eun Hong, Silvia Yumnam, Ho Jeong Lee, Suchismita Raha, Eun Hee Kim, Paik Soon Young & Gon Sup Kim. (2014) Proteome profiling of lipopolysaccharide induced L6 rat skeletal muscle cells response to flavonoids from Scutellaria baicalensis Georgi. BMC Complementary and Alternative Medicine 14:1.
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A. Wiebrecht & A. Kalg. (2014) Letter: herbal hepatotoxicity – an update on traditional Chinese medicine preparations. Alimentary Pharmacology & Therapeutics 40:6, pages 737-738.
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Amit Agarwal, Prashanth D'Souza, T Sudhakar Johnson, Shekhar M Dethe & CV Chandrasekaran. (2014) Use of in vitro bioassays for assessing botanicals. Current Opinion in Biotechnology 25, pages 39-44.
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Victor J. Navarro & Leonard B. Seeff. (2013) Liver Injury Induced by Herbal Complementary and Alternative Medicine. Clinics in Liver Disease 17:4, pages 715-735.
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Kwang Hoon Song, Sun Hwa Lee, Bu‐Yeo Kim, Ah Yeon Park & Jong Yeol Kim. (2012) Extracts of Scutellaria baicalensis Reduced Body Weight and Blood Triglyceride in db/db Mice . Phytotherapy Research 27:2, pages 244-250.
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Liping Zhao, Jeremy K. Nicholson, Aiping Lu, Zhengtao Wang, Huiru Tang, Elaine Holmes, Jian Shen, Xu Zhang, Jia V. Li & John C. Lindon. (2012) Targeting the Human Genome–Microbiome Axis for Drug Discovery: Inspirations from Global Systems Biology and Traditional Chinese Medicine. Journal of Proteome Research 11:7, pages 3509-3519.
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Lijuan Liu, Wenhong Jiang, Lijie Zhang, Fang Li & Qingbo Zhang. (2011) Chemical correlation between Shuanghuanglian injection and its three raw herbs by LC fingerprint. Journal of Separation Science 34:15, pages 1834-1844.
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Kwang-Il Park, Hyeon-Soo Park, Sang-Rim Kang, Arulkumar Nagappan, Do-Hoon Lee, Jin-A Kim, Dae-Yong Han & Gon-Sup Kim. (2011) Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells. Journal of Ethnopharmacology 133:2, pages 634-641.
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Gjumrakch Aliev, Yury G. Kaminsky, Valentin Bragin, Elena A. Kosenko, Sergey G. Klochkov, Sergey O. Bachurin & Valery V. Benberin. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants 2305 2323 .
Jin Feng, Wen Xu, Xia Tao, Hua Wei, Fei Cai, Bo Jiang & Wansheng Chen. (2010) Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography–tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria–coptis herb couple. Journal of Pharmaceutical and Biomedical Analysis 53:3, pages 591-598.
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M. Eric Gershwin, Andrea T. Borchers, Carl L. Keen, Sheldon Hendler, Frank Hagie & M.R.C. Greenwood. (2010) Public safety and dietary supplementation. Annals of the New York Academy of Sciences 1190:1, pages 104-117.
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Chong-Zhi Wang, Xiao-Li Li, Qian-Fei Wang, Sangeeta R. Mehendale & Chun-Su Yuan. (2010) Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. Phytomedicine 17:1, pages 63-68.
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Sheng-Teng Huang, Chen-Yu Wang, Rong-Chi Yang, Chih-Ju Chu, Hsiao-Ting Wu & Jong-Hwei S. Pang. (2010) Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Phytomedicine 17:1, pages 47-54.
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Rui An, Ying Wang, Lisha You & Xinhong Wang. (2009) UPLC–MS Analysis for Simultaneous Determination of Eight Components in the ‘Ge-Gen-Qin-Lian’ Tablets. Chromatographia 69:9-10, pages 969-975.
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Su Su, Chang‐Ming He, Lin‐Chu Li, Jia‐Kuan Chen & Tong‐Shui Zhou. (2008) Genetic Characterization and Phytochemical Analysis of Wild and Cultivated Populations of Scutellaria baicalensis . Chemistry & Biodiversity 5:7, pages 1353-1363.
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Yantao Sun, Shuyun Bi, Daqian Song, Chunyu Qiao, Dan Mu & Hanqi Zhang. (2008) Study on the interaction mechanism between DNA and the main active components in Scutellaria baicalensis Georgi. Sensors and Actuators B: Chemical 129:2, pages 799-810.
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Young Hoon Kim, Dong Won Jeong, Yoon-Cheol Kim, Dong Hwan Sohn, Eun-Seok Park & Hye Suk Lee. (2007) Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract ofScutellaria baicalensis, PF-2405 in rats. Archives of Pharmacal Research 30:2, pages 260-265.
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Young Hoon Kim, Dong Won Jeong, In Bok Paek, Hye Young Ji, Youn-Chul Kim, Dong Hwan Sohn & Hye Suk Lee. (2006) Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. Journal of Chromatography B 844:2, pages 261-267.
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Harry Brielmann, Peter Kaufman, James Duke, Leland Cseke, Sara Warber & Ara KirakosyanKatherine Irvine & Sara Warber. 2006. Natural Products from Plants, Second Edition. Natural Products from Plants, Second Edition 535 546 .

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