281
Views
63
CrossRef citations to date
0
Altmetric
Original Articles

In Vitro Effects on Polydextrose by Colonic Bacteria and Caco-2 Cell Cyclooxygenase Gene Expression

Pages 94-104 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Oliver Hasselwander, Robert DiCosimo, Zheng You, Qiong Cheng, Steven C. Rothman, Supaporn Suwannakham, Zachary C. Baer, Brian M. Roesch, Kristin D. Ruebling-Jass, Jian Ping Lai, Richard E. Hurteau, Mario L. Marquez, Alexander D. Kopatsis, Arthur C. Ouwehand, Sofia D. Forssten, Pushkor Mukerji, Jessica M. Caverly Rae, Yvonne P. Dragan, James R. Damewood, Kirsti Tiihonen & Alvin Ibarra. (2017) Development of dietary soluble fibres by enzymatic synthesis and assessment of their digestibility in in vitro, animal and randomised clinical trial models. International Journal of Food Sciences and Nutrition 68:7, pages 849-864.
Read now
S. D. Forssten & A. C. Ouwehand. (2017) Simulating colonic survival of probiotics in single-strain products compared to multi-strain products. Microbial Ecology in Health and Disease 28:1.
Read now
R. Hemalatha, A. C. Ouwehand, M. T. Saarinen, U. V. Prasad, K. Swetha & V. Bhaskar. (2017) Effect of probiotic supplementation on total lactobacilli, bifidobacteria and short chain fatty acids in 2–5-year-old children. Microbial Ecology in Health and Disease 28:1.
Read now
Sofia D. Forssten, Henna Röytiö, Ashley A. Hibberd & Arthur C. Ouwehand. (2015) The effect of polydextrose and probiotic lactobacilli in a Clostridium difficile–infected human colonic model. Microbial Ecology in Health and Disease 26:1.
Read now
David E. Lefebvre, Koen Venema, Lourdes Gombau, Luis G. Valerio$suffix/text()$suffix/text(), Jayadev Raju, Genevieve S. Bondy, Hans Bouwmeester, R. Paul Singh, Amy J. Clippinger, Eva-Maria Collnot, Rekha Mehta & Vicki Stone. (2015) Utility of models of the gastrointestinal tract for assessment of the digestion and absorption of engineered nanomaterials released from food matrices. Nanotoxicology 9:4, pages 523-542.
Read now
K. Tiihonen, H. Kettunen, M.H.L. Bento, M. Saarinen, S. Lahtinen, A.C. Ouwehand, H. Schulze & N. Rautonen. (2010) The effect of feeding essential oils on broiler performance and gut microbiota. British Poultry Science 51:3, pages 381-392.
Read now

Articles from other publishers (57)

C. Anandharamakrishnan, Jeyan Arthur Moses & S. Priyanka. 2023. Food Digestion and Absorption. Food Digestion and Absorption 212 289 .
Nicolas Yeung, Sofia D. Forssten, Markku T. Saarinen, Mehreen Anjum & Arthur C. Ouwehand. (2023) The Effect of Delivery Matrix on Bifidobacterium animalis subsp. lactis HN019 Survival through In Vitro Human Digestion. Nutrients 15:16, pages 3541.
Crossref
Krista Salli, Johanna Hirvonen, Heli Anglenius, Ashley A. Hibberd, Ilmari Ahonen, Markku T. Saarinen, Johanna Maukonen & Arthur C. Ouwehand. (2023) The Effect of Human Milk Oligosaccharides and Bifidobacterium longum subspecies infantis Bi-26 on Simulated Infant Gut Microbiome and Metabolites. Microorganisms 11:6, pages 1553.
Crossref
Sofia D. Forssten, Wesley Morovic & Päivi Nurminen. (2023) An in vitro model of the chicken gastrointestinal tract with special emphasis to the cecal microbiota. Poultry Science 102:6, pages 102654.
Crossref
Matilda Kråkström, Alex M. Dickens, Marina Amaral Alves, Sofia D. Forssten, Arthur C. Ouwehand, Tuulia Hyötyläinen, Matej Orešič & Santosh Lamichhane. (2023) Dynamics of the Lipidome in a Colon Simulator. Metabolites 13:3, pages 355.
Crossref
Cheng Li & Xiaowei Zhang. (2022) Current in Vitro and Animal Models for Understanding Foods: Human Gut–Microbiota Interactions. Journal of Agricultural and Food Chemistry 70:40, pages 12733-12745.
Crossref
Liying Zhu, Fangjie Guo, Zeyu Guo, Xiaoqiang Chen, Xiaoguo Qian, Xianglong Li, Xiaoqiong Li, Jinjun Li, Xin Wang & Weiguo Jia. (2022) Potential health benefits of lowering gas production and bifidogenic effect of the blends of polydextrose with inulin in a human gut model. Frontiers in Nutrition 9.
Crossref
Anna Gościniak, Piotr Eder, Jarosław Walkowiak & Judyta Cielecka-Piontek. (2022) Artificial Gastrointestinal Models for Nutraceuticals Research—Achievements and Challenges: A Practical Review. Nutrients 14:13, pages 2560.
Crossref
R.A. RastallM. Diez-MunicioS.D. ForsstenB. HamakerA. MeynierF. Javier MorenoF. RespondekB. StahK. VenemaM. Wiese. (2022) Structure and function of non-digestible carbohydrates in the gut microbiome. Beneficial Microbes 13:2, pages 95-168.
Crossref
Débora Campos, Ricardo Goméz-García, Diana Oliveira & Ana Raquel Madureira. (2021) Intake of nanoparticles and impact on gut microbiota: in vitro and animal models available for testing . Gut Microbiome 3.
Crossref
Elora Fournier, Charlène Roussel, Alessandra Dominicis, Delphine Ley, Marie-Agnès Peyron, Valérie Collado, Muriel Mercier-Bonin, Christophe Lacroix, Monique Alric, Tom Van de Wiele, Christophe Chassard, Lucie Etienne-Mesmin & Stéphanie Blanquet-Diot. (2022) In vitro models of gut digestion across childhood: current developments, challenges and future trends. Biotechnology Advances 54, pages 107796.
Crossref
Sanna M. Mäkelä, Sofia D. Forssten, Marita Kailajärvi, Ville L. Langén, Mika Scheinin, Kirsti Tiihonen & Arthur C. Ouwehand. (2021) Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti‐inflammatory drug: A randomized, placebo‐controlled, double‐blind clinical trial . British Journal of Clinical Pharmacology 87:12, pages 4625-4635.
Crossref
Connor O'Farrell, Konstantinos Stamatopoulos, Mark Simmons & Hannah Batchelor. (2021) In vitro models to evaluate ingestible devices: Present status and current trends. Advanced Drug Delivery Reviews 178, pages 113924.
Crossref
Dalila Roupar, Paulo Berni, Joana T. Martins, Ana C. Caetano, José A. Teixeira & Clarisse Nobre. (2021) Bioengineering approaches to simulate human colon microbiome ecosystem. Trends in Food Science & Technology 112, pages 808-822.
Crossref
Yuan Yue, Ditte S. G. Nielsen, Sofia D. Forssten, Knud Erik B. Knudsen, Markku T. Saarinen, Arthur C. Ouwehand & Stig Purup. (2021) Effects of Colonic Fermentation Products of Polydextrose, Lactitol and Xylitol on Intestinal Barrier Repair In Vitro. Applied Sciences 11:9, pages 4174.
Crossref
Maged Younes, Gabriele Aquilina, Laurence Castle, Karl‐Heinz Engel, Paul Fowler, Peter Fürst, Rainer Gürtler, Ursula Gundert‐Remy, Trine Husøy, Melania Manco, Wim Mennes, Peter Moldeus, Sabina Passamonti, Romina Shah, Dina Hendrika Waalkens‐Berendsen, Detlef Wölfle, Matthew Wright, Polly Boon, Riccardo Crebelli, Alessandro Di Domenico, Metka Filipič, Alicja Mortensen, Ruud Woutersen, Henk Van Loveren, Alessandra Giarola, Federica Lodi, Ana Maria Rincon, Alexandra Tard & Maria Jose Frutos Fernandez. (2021) Re‐evaluation of polydextrose (E 1200) as a food additive. EFSA Journal 19:1.
Crossref
T. R. Keerthi, Rakhie Narayanan, K. Sreelekshmi & C. Honey Chandran. 2021. Probiotic Bacteria and Postbiotic Metabolites: Role in Animal and Human Health. Probiotic Bacteria and Postbiotic Metabolites: Role in Animal and Human Health 61 83 .
Krista Salli, Heli Anglenius, Johanna Hirvonen, Ashley A. Hibberd, Ilmari Ahonen, Markku T. Saarinen, Kirsti Tiihonen, Johanna Maukonen & Arthur C. Ouwehand. (2019) The effect of 2′-fucosyllactose on simulated infant gut microbiome and metabolites; a pilot study in comparison to GOS and lactose. Scientific Reports 9:1.
Crossref
Santosh Lamichhane, Christian C. Yde, Henrik Max Jensen, Wesley Morovic, Ashley A. Hibberd, Arthur C. Ouwehand, Markku T. Saarinen, Sofia D. Forssten, Lars Wiebe, Jørn Marcussen, Kresten Bertelsen, Sebastian Meier, Jette F. Young & Hanne Christine Bertram. (2018) Metabolic Fate of 13 C-Labeled Polydextrose and Impact on the Gut Microbiome: A Triple-Phase Study in a Colon Simulator . Journal of Proteome Research 17:3, pages 1041-1053.
Crossref
Elisa Garuglieri, Erika Meroni, Cristina Cattò, Federica Villa, Francesca Cappitelli & Daniela Erba. (2018) Effects of Sub-lethal Concentrations of Silver Nanoparticles on a Simulated Intestinal Prokaryotic–Eukaryotic Interface. Frontiers in Microbiology 8.
Crossref
Hedda L. Köhling, Sue F. Plummer, Julian R. Marchesi, Kelly S. Davidge & Marian Ludgate. (2017) The microbiota and autoimmunity: Their role in thyroid autoimmune diseases. Clinical Immunology 183, pages 63-74.
Crossref
M. AguirreK. Venema. (2017) Challenges in simulating the human gut for understanding the role of the microbiota in obesity. Beneficial Microbes 8:1, pages 31-53.
Crossref
Kaisa Olli, Markku T. Saarinen, Sofia D. Forssten, Mari Madetoja, Karl-Heinz Herzig & Kirsti Tiihonen. (2016) Independent and Combined Effects of Lactitol, Polydextrose, and Bacteroides thetaiotaomicron on Postprandial Metabolism and Body Weight in Rats Fed a High-Fat Diet. Frontiers in Nutrition 3.
Crossref
. (2016) Polydextrose and maintenance of normal defecation: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006. EFSA Journal 14:5.
Crossref
David Ríos-Covián, Patricia Ruas-Madiedo, Abelardo Margolles, Miguel Gueimonde, Clara G. de los Reyes-Gavilán & Nuria Salazar. (2016) Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health. Frontiers in Microbiology 7.
Crossref
Maria R.C. de GodoyMarta HerveraKelly S. SwansonGeorge C. FaheyJr.Jr.. (2016) Innovations in Canine and Feline Nutrition: Technologies for Food and Nutrition Assessment. Annual Review of Animal Biosciences 4:1, pages 311-333.
Crossref
Santosh Lamichhane, Johan A. Westerhuis, Arthur C. Ouwehand, Markku T. Saarinen, Sofia D. Forssten, Henrik Max Jensen, Jette F. Young, Hanne Christine Bertram & Christian C. Yde. (2016) Gut microbial activity as influenced by fiber digestion: dynamic metabolomics in an in vitro colon simulator. Metabolomics 12:2.
Crossref
C.F. WilliamsG.E. WaltonL. JiangS. PlummerI. GaraiovaG.R. Gibson. (2015) Comparative Analysis of Intestinal Tract Models. Annual Review of Food Science and Technology 6:1, pages 329-350.
Crossref
Tina S. Nielsen, Helle N. Lærke, Peter K. Theil, Jens F. Sørensen, Markku Saarinen, Sofia Forssten & Knud E. Bach Knudsen. (2014) Diets high in resistant starch and arabinoxylan modulate digestion processes and SCFA pool size in the large intestine and faecal microbial composition in pigs. British Journal of Nutrition 112:11, pages 1837-1849.
Crossref
H. Röytiö & A.C. Ouwehand. (2014) The fermentation of polydextrose in the large intestine and its beneficial effects. Beneficial Microbes 5:3, pages 305-313.
Crossref
Ana Gomes, Manuela Pintado & J Sousa e Silva. 2014. Probiotic Bacteria. Probiotic Bacteria 7 45 .
Koen Venema. 2014. Food Oligosaccharides. Food Oligosaccharides 217 237 .
A. C. Ouwehand, S. J. M. ten Bruggencate, A. J. Schonewille, E. Alhoniemi, S. D. Forssten & I. M. J. Bovee-Oudenhoven. (2013) Lactobacillus acidophilus supplementation in human subjects and their resistance to enterotoxigenic Escherichia coli infection . British Journal of Nutrition 111:3, pages 465-473.
Crossref
Sofia Forssten. (2014) Influence of a probiotic mixture on antibiotic induced microbiota disturbances. World Journal of Gastroenterology 20:33, pages 11878.
Crossref
Nadja Larsen, Finn K. Vogensen, Rikke Juul Gøbel, Kim F. Michaelsen, Sofia D. Forssten, Sampo J. Lahtinen & Mogens Jakobsen. (2013) Effect of Lactobacillus salivarius Ls-33 on fecal microbiota in obese adolescents. Clinical Nutrition 32:6, pages 935-940.
Crossref
Koen Venema & Pieter van den Abbeele. (2013) Experimental models of the gut microbiome. Best Practice & Research Clinical Gastroenterology 27:1, pages 115-126.
Crossref
Gemma E. Walton, Jonathan R. Swann & Glenn R. Gibson. 2013. The Prokaryotes. The Prokaryotes 25 43 .
Henna Röytiö, Kirsti Tiihonen & Arthur C. Ouwehand. 2012. Sweeteners and Sugar Alternatives in Food Technology. Sweeteners and Sugar Alternatives in Food Technology 63 76 .
Alison N. Beloshapka, Amanda K. Wolff & Kelly S. Swanson. (2011) Effects of feeding polydextrose on faecal characteristics, microbiota and fermentative end products in healthy adult dogs. British Journal of Nutrition 108:4, pages 638-644.
Crossref
Adele Costabile, Francesca Fava, Henna Röytiö, Sofia D. Forssten, Kaisa Olli, Judith Klievink, Ian R. Rowland, Arthur C. Ouwehand, Robert A. Rastall, Glenn R. Gibson & Gemma E. Walton. (2011) Impact of polydextrose on the faecal microbiota: a double-blind, crossover, placebo-controlled feeding study in healthy human subjects. British Journal of Nutrition 108:3, pages 471-481.
Crossref
A. Roessler, S.D. Forssten, M. Glei, A.C. Ouwehand & G. Jahreis. (2012) The effect of probiotics on faecal microbiota and genotoxic activity of faecal water in patients with atopic dermatitis: A randomized, placebo-controlled study. Clinical Nutrition 31:1, pages 22-29.
Crossref
Heli Putaala, Harri Mäkivuokko, Kirsti Tiihonen & Nina Rautonen. (2011) Simulated colon fiber metabolome regulates genes involved in cell cycle, apoptosis, and energy metabolism in human colon cancer cells. Molecular and Cellular Biochemistry 357:1-2, pages 235-245.
Crossref
Kaisa Raninen, Jenni Lappi, Hannu Mykkänen & Kaisa Poutanen. (2011) Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose. Nutrition Reviews 69:1, pages 9-21.
Crossref
Trevor A. Faber & George C. FaheyJr.Jr.. 2010. Nondigestible Carbohydrates and Digestive Health. Nondigestible Carbohydrates and Digestive Health 97 123 .
H. Mäkivuokko, S. Forssten, M. Saarinen, A. Ouwehand & N. Rautonen. (2010) Synbiotic effects of lactitol and Lactobacillus acidophilus NCFM™ in a semi-continuous colon fermentation model . Beneficial Microbes 1:2, pages 131-137.
Crossref
Kirsti Tiihonen, Arthur C. Ouwehand & Nina Rautonen. (2009) Effect of overweight on gastrointestinal microbiology and immunology: correlation with blood biomarkers. British Journal of Nutrition 103:7, pages 1070-1078.
Crossref
R.A. Rastall. (2010) Functional Oligosaccharides: Application and Manufacture. Annual Review of Food Science and Technology 1:1, pages 305-339.
Crossref
H. Mäkeläinen, O. Hasselwander, N. Rautonen & A.C. Ouwehand. (2009) Panose, a new prebiotic candidate. Letters in Applied Microbiology 49:6, pages 666-672.
Crossref
H. Mäkeläinen, S. Forssten, K. Olli, L. Granlund, N. Rautonen & A.C. Ouwehand. (2009) Probiotic lactobacilli in a semi-soft cheese survive in the simulated human gastrointestinal tract. International Dairy Journal 19:11, pages 675-683.
Crossref
Julian Stowell. 2009. Fiber Ingredients. Fiber Ingredients.
Arthur C. Ouwehand, Kirsti Tiihonen, Markku Saarinen, Heli Putaala & Nina Rautonen. (2008) Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters . British Journal of Nutrition 101:3, pages 367-375.
Crossref
A.C. Ouwehand, K. Tiihonen, H. Mäkeläinen, N. Rautonen, O. Hasselwander & G. Sworn. 2009. Designing Functional Foods. Designing Functional Foods 126 147 .
Julian D. Stowell. 2009. Prebiotics and Probiotics Science and Technology. Prebiotics and Probiotics Science and Technology 337 352 .
Francesca Fava, Harri Mäkivuokko, Hilkka Siljander-Rasi, Heli Putaala, Kirsti Tiihonen, Julian Stowell, Kieran Tuohy, Glenn Gibson & Nina Rautonen. (2007) Effect of polydextrose on intestinal microbes and immune functions in pigs. British Journal of Nutrition 98:1, pages 123-133.
Crossref
H.S. Mäkeläinen, H.A. Mäkivuokko, S.J. Salminen, N.E. Rautonen & A.C. Ouwehand. (2007) The Effects of Polydextrose and Xylitol on Microbial Community and Activity in a 4-Stage Colon Simulator. Journal of Food Science 72:5, pages M153-M159.
Crossref
Arthur C. Ouwehand, Henna Mkelinen, Kirsti Tiihonen & Nina Rautonen. 2006. Sweeteners and Sugar Alternatives in Food Technology. Sweeteners and Sugar Alternatives in Food Technology 44 53 .
Harri Mäkivuokko & Päivi Nurminen. 2006. Gastrointestinal Microbiology. Gastrointestinal Microbiology 237 252 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.