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Original Articles

Effect of a Tomato Drink Intervention on Insulin-Like Growth Factor (IGF)-1 Serum Levels in Healthy Subjects

Pages 157-162 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Peter H. Gann, Ryan J. Deaton, Erika Enk Rueter, Richard B. van Breemen, Larisa Nonn, Virgilia Macias, Misop Han & Viju Ananthanarayanan. (2015) A Phase II Randomized Trial of Lycopene-Rich Tomato Extract Among Men with High-Grade Prostatic Intraepithelial Neoplasia. Nutrition and Cancer 67:7, pages 1104-1112.
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Torsten Bohn, Michelle Blackwood, David Francis, Qingguo Tian, StevenJ. Schwartz & StevenK. Clinton. (2013) Bioavailability of Phytochemical Constituents From a Novel Soy Fortified Lycopene Rich Tomato Juice Developed for Targeted Cancer Prevention Trials. Nutrition and Cancer 65:6, pages 919-929.
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Jane Teas, MohammadR. Irhimeh, Susan Druker, ThomasG. Hurley, JamesR. Hébert, ToddM. Savarese & MindyS. Kurzer. (2011) Serum IGF-1 Concentrations Change With Soy and Seaweed Supplements in Healthy Postmenopausal American Women. Nutrition and Cancer 63:5, pages 743-748.
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Karin Wertz. (2009) Lycopene Effects Contributing to Prostate Health. Nutrition and Cancer 61:6, pages 775-783.
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Patrizia Riso, Daniela Martini, Francesco Visioli, Antonia Martinetti & Marisa Porrini. (2009) Effect of Broccoli Intake on Markers Related to Oxidative Stress and Cancer Risk in Healthy Smokers and Nonsmokers. Nutrition and Cancer 61:2, pages 232-237.
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DorienW. Voskuil, Alina Vrieling, CatharinaM. Korse, JosH. Beijnen, JohannesM. G. Bonfrer, Jaap van Doorn, Reinie Kaas, HesterS. A. Oldenburg, NicolaS. Russell, EmielJ. T. Rutgers, Senno Verhoef, FloraE. van Leeuwen, LauraJ. van't Veer & MattiA. Rookus. (2008) Effects of Lycopene on the Insulin-Like Growth Factor (IGF) System in Premenopausal Breast Cancer Survivors and Women at High Familial Breast Cancer Risk. Nutrition and Cancer 60:3, pages 342-353.
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Articles from other publishers (29)

Vittoria Rago & Silvia Di Agostino. (2023) Novel Insights into the Role of the Antioxidants in Prostate Pathology. Antioxidants 12:2, pages 289.
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Alireza Sadeghi, Ahmad Saedisomeolia, Leili Jalili-Baleh, Mehdi Khoobi, Mohammad Soleimani, Ali Mohammad Fakhr Yasseri, Mir Saeed Yekaninejad, Amirreza Farzin, Erfan Amini & Mohammad Reza Nowroozi. (2022) FruHis significantly increases the anti-benign prostatic hyperplasia effect of lycopene: A double-blinded randomized controlled clinical trial. Frontiers in Nutrition 9.
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Anna Zasowska-Nowak, Piotr Jan Nowak & Aleksandra Cialkowska-Rysz. (2022) Carotenoids in Palliative Care—Is There Any Benefit from Carotenoid Supplementation in the Adjuvant Treatment of Cancer-Related Symptoms?. Nutrients 14:15, pages 3183.
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Ming-Ju Hsieh, Chih-Yang Huang, Rudolf Kiefer, Shin-Da Lee, Nancy Maurya & Bharath Kumar Velmurugan. (2022) Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors. Molecules 27:10, pages 3235.
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Fatemeh Meshkini, Nahid Ramezani‐Jolfaie, Saman Sargazi, Cain C.T. Clark & Sepideh Soltani. (2022) The effects of lycopene supplementation on insulin‐like growth factor‐1 and insulin‐like growth factor binding proteins: A systematic review of randomized controlled trials . Phytotherapy Research 36:4, pages 1633-1643.
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Zhihong Xie & Feng Yang. (2021) The effects of lycopene supplementation on serum insulin-like growth factor 1 (IGF-1) levels and cardiovascular disease: A dose-response meta-analysis of clinical trials. Complementary Therapies in Medicine 56, pages 102632.
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Kalina M. Biernacka, Jeff M.P. Holly, Richard M. Martin, Aleksandra Frankow, Caroline J. Bull, Freddie C. Hamdy, Jenny L. Donovan, David E. Neal, Chris Metcalfe & Athene Lane. (2019) Effect of green tea and lycopene on the insulin-like growth factor system: the ProDiet randomized controlled trial. European Journal of Cancer Prevention 28:6, pages 569-575.
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Kazim Sahin, Shakir Ali, Nurhan Sahin, Cemal Orhan & Omer Kucuk. 2017. Natural Products and Cancer Drug Discovery. Natural Products and Cancer Drug Discovery.
Rebecca E Graff, Andreas Pettersson, Rosina T Lis, Thomas U Ahearn, Sarah C Markt, Kathryn M Wilson, Jennifer R Rider, Michelangelo Fiorentino, Stephen Finn, Stacey A Kenfield, Massimo Loda, Edward L Giovannucci, Bernard Rosner & Lorelei A Mucci. (2016) Dietary lycopene intake and risk of prostate cancer defined by ERG protein expression. The American Journal of Clinical Nutrition 103:3, pages 851-860.
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Anja Diener & Sabine Rohrmann. (2016) Associations of serum carotenoid concentrations and fruit or vegetable consumption with serum insulin-like growth factor (IGF)-1 and IGF binding protein-3 concentrations in the Third National Health and Nutrition Examination Survey (NHANES III). Journal of Nutritional Science 5.
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Karin Linnewiel-Hermoni, Yair Motro, Yifat Miller, Joseph Levy & Yoav Sharoni. (2014) Carotenoid derivatives inhibit nuclear factor kappa B activity in bone and cancer cells by targeting key thiol groups. Free Radical Biology and Medicine 75, pages 105-120.
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Gamze Aydemir, Yasamin Kasiri, Eszter Birta, Gabriella Béke, Ada L. Garcia, Emőke-Márta Bartók & Ralph Rühl. (2013) Lycopene-derived bioactive retinoic acid receptors/retinoid-X receptors-activating metabolites may be relevant for lycopene's anti-cancer potential. Molecular Nutrition & Food Research 57:5, pages 739-747.
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Nikki Ford & John W. ErdmanJr.Jr.. 2013. Carotenoids and Human Health. Carotenoids and Human Health 193 214 .
Paola Palozza, Rossella E. Simone, Assunta Catalano & Maria Cristina Mele. (2011) Tomato Lycopene and Lung Cancer Prevention: From Experimental to Human Studies. Cancers 3:2, pages 2333-2357.
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Nancy N. Maserejian, Edward L. Giovannucci, Kevin T. McVary & John B. McKinlay. (2011) Dietary, but Not Supplemental, Intakes of Carotenoids and Vitamin C Are Associated with Decreased Odds of Lower Urinary Tract Symptoms in Men,. The Journal of Nutrition 141:2, pages 267-273.
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Yaxiong Tang, Basmina Parmakhtiar, Anne R. Simoneau, Jun Xie, John Fruehauf, Michael Lilly & Xiaolin Zi. (2011) Lycopene Enhances Docetaxel's Effect in Castration-Resistant Prostate Cancer Associated with Insulin-like Growth Factor I Receptor Levels. Neoplasia 13:2, pages 108-119.
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June M. Chan, Vivian Weinberg, Mark J. Magbanua, Eduardo Sosa, Jeffry Simko, Katsuto Shinohara, Scot Federman, Mike Mattie, Millie Hughes-Fulford, Christopher Haqq & Peter R. Carroll. (2010) Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer. Cancer Causes & Control 22:1, pages 141-150.
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Joseph Levy, Shlomo Walfisch, Andrea Atzmon, Keren Hirsch, Marina Khanin, Karin Linnewiel, Yael Morag, Hagar Salman, Anna Veprik, Michael Danilenko & Yoav Sharoni. 2011. Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention. Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention 47 66 .
Rajat Sandhir, Arpit Mehrotra & Sukhdev S. Kamboj. (2010) Lycopene prevents 3-nitropropionic acid-induced mitochondrial oxidative stress and dysfunctions in nervous system. Neurochemistry International 57:5, pages 579-587.
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Michael Bergman, Meir Djaldetti, Hertzel Salman & Hanna Bessler. (2010) On the combined effect of statins and lycopene on cytokine production by human peripheral blood cells. Heart and Vessels 25:5, pages 426-431.
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Erica N. StoryRachel E. KopecSteven J. SchwartzG. Keith Harris. (2010) An Update on the Health Effects of Tomato Lycopene. Annual Review of Food Science and Technology 1:1, pages 189-210.
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Kin-Weng Kong, Hock-Eng Khoo, K. Nagendra Prasad, Amin Ismail, Chin-Ping Tan & Nor Fadilah Rajab. (2010) Revealing the Power of the Natural Red Pigment Lycopene. Molecules 15:2, pages 959-987.
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Sabine Ellinger. 2010. Bioactive Foods in Promoting Health. Bioactive Foods in Promoting Health 343 357 .
Daniella Markovitch, Rex M. Tyrrell, Pedro Tauler, Jan Frystyk, Keith Stokes & Dylan Thompson. (2009) Lycopene supplementation (passata sauce) reduces apoptosis but does not affect oxidant-responsive heme oxygenase-1 in human lymphocytes. Nutrition 25:6, pages 668-675.
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John W. ErdmanJr.Jr., Nikki A. Ford & Brian L. Lindshield. (2009) Are the health attributes of lycopene related to its antioxidant function?. Archives of Biochemistry and Biophysics 483:2, pages 229-235.
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Joseph Levy, Shlomo Walfisch, Yossi Walfisch, Amit Nahum, Keren Hirsch, Michael Danilenko & Yoav Sharoni. 2008. Tomatoes and Tomato Products. Tomatoes and Tomato Products 395 410 .
Concepción Sánchez-Moreno, Begoña Ancos, Lucía Plaza, Pedro Elez-Martínez & M Cano. 2008. Tomatoes and Tomato Products. Tomatoes and Tomato Products 235 258 .
Alina Vrieling, Dorien W Voskuil, Johannes M Bonfrer, Catharina M Korse, Jaap van Doorn, Annemieke Cats, Annekatrien C Depla, Robin Timmer, Ben J Witteman, Flora E van Leeuwen, Laura J van’t Veer, Matti A Rookus & Ellen Kampman. (2007) Lycopene supplementation elevates circulating insulin-like growth factor–binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer. The American Journal of Clinical Nutrition 86:5, pages 1456-1462.
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R Graydon, S E C M Gilchrist, I S Young, U Obermüller-Jevic, O Hasselwander & J V Woodside. (2007) Effect of lycopene supplementation on insulin-like growth factor-1 and insulin-like growth factor binding protein-3: a double-blind, placebo-controlled trial. European Journal of Clinical Nutrition 61:10, pages 1196-1200.
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