Search in:

Bioscience, Biotechnology, and Biochemistry Volume 75, 2011 - Issue 9

Journal homepage

Full access

1,079

Views

115

CrossRef citations to date

Altmetric

Original Articles

Purification and Characterization of a Novel (R)-Imine Reductase from Streptomyces sp. GF3587

Koichi MITSUKURADepartment of Biomolecular Science, Faculty of Engineering, Gifu University

Mai SUZUKIDepartment of Biomolecular Science, Faculty of Engineering, Gifu University

Sho SHINODADepartment of Biomolecular Science, Faculty of Engineering, Gifu University

Tatsuya KURAMOTODepartment of Biomolecular Science, Faculty of Engineering, Gifu University

Toyokazu YOSHIDADepartment of Biomolecular Science, Faculty of Engineering, Gifu University

Toru NAGASAWADepartment of Biomolecular Science, Faculty of Engineering, Gifu University

Pages 1778-1782 | Received 15 Apr 2011, Accepted 14 Jun 2011, Published online: 22 May 2014

Cite this article
https://doi.org/10.1271/bbb.110303

References
Citations
Metrics
Reprints & Permissions
View PDF PDF

Citations (115)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Articles from other publishers (115)

Bo Yuan, Dameng Yang, Ge Qu, Nicholas J. Turner & Zhoutong Sun. (2024) Biocatalytic reductive aminations with NAD(P)H-dependent enzymes: enzyme discovery, engineering and synthetic applications. Chemical Society Reviews.
Crossref

Davide Arnodo, Federica De Nardi, Stefano Parisotto, Eugenio De Nardo, Stefania Cananà, Federica Salvatico, Elisa De Marchi, Dina Scarpi, Marco Blangetti, Ernesto G. Occhiato & Cristina Prandi. (2023) Asymmetric Reduction of Cyclic Imines by Imine Reductase Enzymes in Non‐Conventional Solvents. ChemSusChem.
Crossref

Patrícia de Carvalho Ribeiro, Lucas Felipe Oliveira, Daniel Mendes Filho, Ricardo Cambraia Parreira, Mariana Sousa Vieira, Bruno Lemes Marques, Elis Marra da Madeira Freitas, Walison N. Silva, Helton da Costa Santiago, Alexander Birbrair, Henning Ulrich, Valdo José Dias da Silva & Rodrigo R. Resende. (2023) Biomarkers in Hypertension and Hypertension-related Disorders. Current Medicinal Chemistry 30:34, pages 3846-3879.
Crossref

Tingting Li, Qian Zhou, Fanjing Meng, Wenhui Cui, Qian Li, Jiang Zhu & Yang Cao. (2023) Asymmetric Reductive Amination in Organocatalysis and Biocatalysis. European Journal of Organic Chemistry.
Crossref

Fangfang Zhu, Jun Zhang, Yaqing Ma, Lujia Yang, Qiang Gao, Shushan Gao & Chengsen Cui. (2023) Semi-rational design of an imine reductase for asymmetric synthesis of alkylated S -4-azepanamines . Organic & Biomolecular Chemistry 21:20, pages 4181-4184.
Crossref

Jun Zhang, Yaqing Ma, Fangfang Zhu, Jinping Bao, Qiaqing Wu, Shu-Shan Gao & Chengsen Cui. (2023) Structure-guided semi-rational design of an imine reductase for enantio-complementary synthesis of pyrrolidinamine. Chemical Science 14:16, pages 4265-4272.
Crossref

Anshul Rajput, Tanaya Manna, Amit Mondal, Arijit De, Jhilik Mondal & Syed Masood Husain. (2023) Biocatalytic Access to Chiral Benzazepines Using Imine Reductases. ACS Catalysis, pages 6185-6194.
Crossref

Yitong Li, Xiaoping Yue, Zhining Li, Zedu Huang & Fener Chen. (2023) Asymmetric Synthesis of Sterically Hindered 1-Substituted Tetrahydro-β-carbolines Enabled by Imine Reductase: Enzyme Discovery, Protein Engineering, and Reaction Development. Organic Letters 25:8, pages 1285-1289.
Crossref

Fei-Fei Chen, Xue-Feng He, Xin-Xin Zhu, Zhi Zhang, Xin-Yuan Shen, Qi Chen, Jian-He Xu, Nicholas J. Turner & Gao-Wei Zheng. (2023) Discovery of an Imine Reductase for Reductive Amination of Carbonyl Compounds with Sterically Challenging Amines. Journal of the American Chemical Society.
Crossref

Yuta Fukawa, Keita Yoshida, Sayaka Degura, Koichi Mitsukura & Toyokazu Yoshida. (2022) Improvement of ( S )-selective imine reductase GF3546 for the synthesis of chiral cyclic amines . Chemical Communications 58:95, pages 13222-13225.
Crossref

Jun Zhang, Xin Li, Rongchang Chen, Xianwei Tan, Xiongduo Liu, Yaqing Ma, Fangfang Zhu, Chunyan An, Guangzheng Wei, Yongpeng Yao, Lujia Yang, Peng Zhang, Qiaqing Wu, Zhoutong Sun, Bin-Gui Wang, Shu-Shan Gao & Chengsen Cui. (2022) Actinomycetes-derived imine reductases with a preference towards bulky amine substrates. Communications Chemistry 5:1.
Crossref

Linsong Yang, Jianjiong Li, Zefei Xu, Peiyuan Yao, Qiaqing Wu, Dunming Zhu & Yanhe Ma. (2022) Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2-Arylethylamines via a Chemoenzymatic Approach. Organic Letters 24:36, pages 6531-6536.
Crossref

Zhuangzhuang Zhan, Zefei Xu, Shanshan Yu, Jinhui Feng, Fufeng Liu, Peiyuan Yao, Qiaqing Wu & Dunming Zhu. (2022) Stereocomplementary Synthesis of a Key Intermediate for Tofacitinib via Enzymatic Dynamic Kinetic Resolution‐Reductive Amination. Advanced Synthesis & Catalysis 364:14, pages 2380-2386.
Crossref

Laura M. Bernhard, Jill McLachlan & Harald Gröger. (2022) Process Development of Enantioselective Imine Reductase-Catalyzed Syntheses of Pharmaceutically Relevant Pyrrolidines. Organic Process Research & Development 26:7, pages 2067-2074.
Crossref

Wojciech Zawodny & Sarah Louise Montgomery. (2022) Evolving New Chemistry: Biocatalysis for the Synthesis of Amine-Containing Pharmaceuticals. Catalysts 12:6, pages 595.
Crossref

Amelia K. Gilio, Thomas W. Thorpe, Nicholas Turner & Gideon Grogan. (2022) Reductive aminations by imine reductases: from milligrams to tons. Chemical Science 13:17, pages 4697-4713.
Crossref

Ana I. Benítez-Mateos, David Roura Padrosa & Francesca Paradisi. (2022) Multistep enzyme cascades as a route towards green and sustainable pharmaceutical syntheses. Nature Chemistry 14:5, pages 489-499.
Crossref

Alina Kinner, Philipp Nerke, Regine Siedentop, Till Steinmetz, Thomas Classen, Katrin Rosenthal, Markus Nett, Jörg Pietruszka & Stephan Lütz. (2022) Recent Advances in Biocatalysis for Drug Synthesis. Biomedicines 10:5, pages 964.
Crossref

Thomas W. Thorpe, James R. Marshall, Vanessa Harawa, Rebecca E. Ruscoe, Anibal Cuetos, James D. Finnigan, Antonio Angelastro, Rachel S. Heath, Fabio Parmeggiani, Simon J. Charnock, Roger M. Howard, Rajesh Kumar, David S. B. Daniels, Gideon Grogan & Nicholas J. Turner. (2022) Multifunctional biocatalyst for conjugate reduction and reductive amination. Nature 604:7904, pages 86-91.
Crossref

Ming Li, Yunfeng Cui, Zefei Xu, Xi Chen, Jinhui Feng, Min Wang, Peiyuan Yao, Qiaqing Wu & Dunming Zhu. (2021) Asymmetric Synthesis of N ‐Substituted γ‐Amino Esters and γ‐Lactams Containing α,γ‐Stereogenic Centers via a Stereoselective Enzymatic Cascade . Advanced Synthesis & Catalysis 364:2, pages 372-379.
Crossref

M.V.N. Uma Mahesh, Mohammed A. Faidh & Anju Chadha. (2022) The ornithine cyclodeaminase/µ-crystallin superfamily of proteins: A novel family of oxidoreductases for the biocatalytic synthesis of chiral amines. Current Research in Biotechnology 4, pages 402-419.
Crossref

Rajesh Kumar, Carlos A. Martinez & John W. Wong. 2022. Green Chemistry in Drug Discovery. Green Chemistry in Drug Discovery 375 401 .

Mario Prejanò, Xiang Sheng & Fahmi Himo. (2021) Computational Study of Mechanism and Enantioselectivity of Imine Reductase from Amycolatopsis orientalis . ChemistryOpen 11:1.
Crossref

César Iglesias, Ariel Tijman, Gonzalo López, María Inés Lapaz, María Julia Pianzzola, Paola Panizza & Sonia Rodríguez Giordano. (2021) Identification, Characterization, and In Silico Analysis of New Imine Reductases From Native Streptomyces Genomes. Frontiers in Catalysis 1.
Crossref

Alina Stein, Dongping Chen, Nico V. Igareta, Yoann Cotelle, Johannes G. Rebelein & Thomas R. Ward. (2021) A Dual Anchoring Strategy for the Directed Evolution of Improved Artificial Transfer Hydrogenases Based on Carbonic Anhydrase. ACS Central Science 7:11, pages 1874-1884.
Crossref

Juan Mangas‐Sanchez, Sebastian C. Cosgrove & Nicholas J. Turner. 2021. Protein Engineering. Protein Engineering 265 294 .

V.N.M. Uma Mahesh & Anju Chadha. (2021) Imine reduction by an Ornithine cyclodeaminase/μ-crystallin homolog purified from Candida parapsilosis ATCC 7330. Biotechnology Reports 31, pages e00664.
Crossref

Emmanuel Cigan, Bettina Eggbauer, Joerg H. Schrittwieser & Wolfgang Kroutil. (2021) The role of biocatalysis in the asymmetric synthesis of alkaloids – an update. RSC Advances 11:45, pages 28223-28270.
Crossref

Yuta Fukawa, Yuta Mizuno, Keisuke Kawade, Koichi Mitsukura & Toyokazu Yoshida. (2021) Novel (S)-Selective Hydrolase from Arthrobacter sp. K5 for Kinetic Resolution of Cyclic Amines. Catalysts 11:7, pages 809.
Crossref

Francesco G. Mutti & Tanja Knaus. 2021. Biocatalysis for Practitioners. Biocatalysis for Practitioners 143 180 .

Itziar Peñafiel, Juan Mangas‐Sánchez & Carmen Claver. 2021. Asymmetric Hydrogenation and Transfer Hydrogenation. Asymmetric Hydrogenation and Transfer Hydrogenation 281 305 .

Sebastian C. Cosgrove, Jeremy I. Ramsden, Juan Mangas‐Sanchez & Nicholas J. Turner. 2021. Methodologies in Amine Synthesis. Methodologies in Amine Synthesis 243 283 .

James R. Marshall, Peiyuan Yao, Sarah L. Montgomery, James D. Finnigan, Thomas W. Thorpe, Ryan B. Palmer, Juan Mangas-Sanchez, Richard A. M. Duncan, Rachel S. Heath, Kirsty M. Graham, Darren J. Cook, Simon J. Charnock & Nicholas J. Turner. (2020) Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination. Nature Chemistry 13:2, pages 140-148.
Crossref

Laurine Ducrot, Megan Bennett, Gideon Grogan & Carine Vergne‐Vaxelaire. (2020) NAD(P)H‐Dependent Enzymes for Reductive Amination: Active Site Description and Carbonyl‐Containing Compound Spectrum. Advanced Synthesis & Catalysis 363:2, pages 328-351.
Crossref

Shuke Wu, Radka Snajdrova, Jeffrey C. Moore, Kai Baldenius & Uwe T. Bornscheuer. (2020) Biocatalysis: Enzymatic Synthesis for Industrial Applications. Angewandte Chemie International Edition 60:1, pages 88-119.
Crossref

Shuke Wu, Radka Snajdrova, Jeffrey C. Moore, Kai Baldenius & Uwe T. Bornscheuer. (2020) Biokatalyse: Enzymatische Synthese für industrielle Anwendungen. Angewandte Chemie 133:1, pages 89-123.
Crossref

Katrin Hecht, Hans-Peter Meyer, Roland Wohlgemuth & Rebecca Buller. (2020) Biocatalysis in the Swiss Manufacturing Environment. Catalysts 10:12, pages 1420.
Crossref

Anderson R. Aguillón, Amanda S. Miranda, Ivaldo I. Junior & Rodrigo O. M. A. Souza. 2020. Synthetic Approaches to Nonaromatic Nitrogen Heterocycles. Synthetic Approaches to Nonaromatic Nitrogen Heterocycles 667 697 .

Sebastian Roth, Peter Stockinger, Jakob Steff, Simon Steimle, Viktor Sautner, Kai Tittmann, Jürgen Pleiss & Michael Müller. (2020) Crossing the Border: From Keto‐ to Imine Reduction in Short‐Chain Dehydrogenases/Reductases. ChemBioChem 21:18, pages 2615-2619.
Crossref

Lars‐Erik Meyer, Henrike Brundiek & Jan Langermann. (2020) Integration of ion exchange resin materials for a downstream‐processing approach of an imine reductase‐catalyzed reaction . Biotechnology Progress 36:5.
Crossref

Timo Meyer, Nadine Zumbrägel, Christina Geerds, Harald Gröger & Hartmut H. Niemann. (2020) Structural Characterization of an S-enantioselective Imine Reductase from Mycobacterium Smegmatis. Biomolecules 10:8, pages 1130.
Crossref

Sarah L. Montgomery, Ahir PushpanathRachel S. Heath, James R. Marshall, Ulrike KlemsteinJames L. Galman, David Woodlock, Serena Bisagni, Christopher J. Taylor, J. Mangas-Sanchez, J. I. RamsdenBeatriz DominguezNicholas J. Turner. (2020) Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships. Science Advances 6:21.
Crossref

Juan Mangas-Sanchez, Mahima Sharma, Sebastian C. Cosgrove, Jeremy I. Ramsden, James R. Marshall, Thomas W. Thorpe, Ryan B. Palmer, Gideon Grogan & Nicholas J. Turner. (2020) Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases. Chemical Science 11:19, pages 5052-5057.
Crossref

Yu-Hui Zhang, Fei-Fei Chen, Bo-Bo Li, Xin-Yi Zhou, Qi Chen, Jian-He Xu & Gao-Wei Zheng. (2020) Stereocomplementary Synthesis of Pharmaceutically Relevant Chiral 2-Aryl-Substituted Pyrrolidines Using Imine Reductases. Organic Letters 22:9, pages 3367-3372.
Crossref

Natália Alvarenga, Stefan E. Payer, Philipp Petermeier, Christoph Kohlfuerst, André Luiz Meleiro Porto, Joerg H. Schrittwieser & Wolfgang Kroutil. (2019) Asymmetric Synthesis of Dihydropinidine Enabled by Concurrent Multienzyme Catalysis and a Biocatalytic Alternative to Krapcho Dealkoxycarbonylation. ACS Catalysis 10:2, pages 1607-1620.
Crossref

Niels Borlinghaus, Leonie Weinmann, Florian Krimpzer, Philipp N. Scheller, Ammar Al‐Shameri, Lars Lauterbach, Anne‐Sophie Coquel, Claus Lattemann, Bernhard Hauer & Bettina M. Nestl. (2019) Cascade Biotransformation to Access 3‐Methylpiperidine in Whole Cells. ChemCatChem 11:23, pages 5738-5742.
Crossref

Matthias Höhne. (2019) Engineering imine reductases for industrial applications. Nature Catalysis 2:10, pages 841-842.
Crossref

Jin Guo, Melanie A. Higgins, Phillip Daniel-Ivad & Katherine S. Ryan. (2019) An Asymmetric Reductase That Intercepts Acyclic Imino Acids Produced in Situ by a Partner Oxidase . Journal of the American Chemical Society 141:31, pages 12258-12267.
Crossref

Amin Bornadel, Serena BisagniAhir PushpanathSarah L. Montgomery, Nicholas J. Turner & Beatriz Dominguez. (2019) Technical Considerations for Scale-Up of Imine-Reductase-Catalyzed Reductive Amination: A Case Study. Organic Process Research & Development 23:6, pages 1262-1268.
Crossref

Joseph P. AdamsMurray J. B. BrownAlba Diaz‐RodriguezRichard C. LloydGheorghe‐Doru Roiban. (2019) Biocatalysis: A Pharma Perspective. Advanced Synthesis & Catalysis.
Crossref

Nadine Zumbrägel, Paul Machui, Jannis Nonnhoff & Harald Gröger. (2018) Enantioselective Biocatalytic Reduction of 2 H -1,4-Benzoxazines Using Imine Reductases . The Journal of Organic Chemistry 84:3, pages 1440-1447.
Crossref

Nadine Zumbrägel & Harald Gröger. (2019) One-pot synthesis of a 3-thiazolidine through combination of an Asinger-type multi-component-condensation reaction with an enzymatic imine reduction. Journal of Biotechnology 291, pages 35-40.
Crossref

Peiyuan Yao, Zefei Xu, Shanshan Yu, Qiaqing Wu & Dunming Zhu. (2018) Imine Reductase‐Catalyzed Enantioselective Reduction of Bulky α,β‐Unsaturated Imines en Route to a Pharmaceutically Important Morphinan Skeleton. Advanced Synthesis & Catalysis 361:3, pages 556-561.
Crossref

Wojciech Zawodny, Sarah L. Montgomery, James R. Marshall, James D. Finnigan, Nicholas J. Turner & Jonathan Clayden. (2018) Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement. Journal of the American Chemical Society 140:51, pages 17872-17877.
Crossref

Mahesh D. Patil, Gideon Grogan, Andreas Bommarius & Hyungdon Yun. (2018) Oxidoreductase-Catalyzed Synthesis of Chiral Amines. ACS Catalysis 8:12, pages 10985-11015.
Crossref

Bruna Z. Costa, James L. GalmanIustina SlabuScott P. FranceAnita J. Marsaioli & Nicholas J. Turner. (2018) Synthesis of 2,5-Disubstituted Pyrrolidine Alkaloids via A One-Pot Cascade Using Transaminase and Reductive Aminase Biocatalysts . ChemCatChem 10:20, pages 4733-4738.
Crossref

David L. Hughes. (2018) Biocatalysis in Drug Development—Highlights of the Recent Patent Literature. Organic Process Research & Development 22:9, pages 1063-1080.
Crossref

Sebastian Roth, Matthew B. Kilgore, Toni M. Kutchan & Michael Müller. (2018) Exploiting the Catalytic Diversity of Short‐Chain Dehydrogenases/Reductases: Versatile Enzymes from Plants with Extended Imine Substrate Scope. ChemBioChem 19:17, pages 1849-1852.
Crossref

Stefan Velikogne, Verena Resch, Carina Dertnig, Joerg H. Schrittwieser & Wolfgang Kroutil. (2018) Sequence‐Based In‐silico Discovery, Characterisation, and Biocatalytic Application of a Set of Imine Reductases . ChemCatChem 10:15, pages 3236-3246.
Crossref

Nadine Zumbrägel, Christian Merten, Stefan M. Huber & Harald Gröger. (2018) Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis. Nature Communications 9:1.
Crossref

Niels Borlinghaus, Sebastian Gergel & Bettina M. Nestl. (2018) Biocatalytic Access to Piperazines from Diamines and Dicarbonyls. ACS Catalysis 8:4, pages 3727-3732.
Crossref

Maike Lenz, Silvia Fademrecht, Mahima Sharma, Jürgen Pleiss, Gideon Grogan & Bettina M Nestl. (2018) New imine-reducing enzymes from β -hydroxyacid dehydrogenases by single amino acid substitutions . Protein Engineering, Design and Selection 31:4, pages 109-120.
Crossref

Gideon Grogan. (2018) Synthesis of chiral amines using redox biocatalysis. Current Opinion in Chemical Biology 43, pages 15-22.
Crossref

Jelena Spasic, Mina Mandic, Lidija Djokic & Jasmina Nikodinovic-Runic. (2018) Streptomyces spp. in the biocatalysis toolbox. Applied Microbiology and Biotechnology 102:8, pages 3513-3536.
Crossref

Martina Hestericová, Tillman Heinisch, Lur Alonso-Cotchico, Jean-Didier Maréchal, Pietro Vidossich & Thomas R. Ward. (2018) Directed Evolution of an Artificial Imine Reductase. Angewandte Chemie International Edition 57:7, pages 1863-1868.
Crossref

Scott P. France, Roger M. Howard, Jeremy Steflik, Nicholas J. Weise, Juan Mangas-Sanchez, Sarah L. Montgomery, Robert Crook, Rajesh Kumar & Nicholas J. Turner. (2018) Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination. ChemCatChem 10:3, pages 510-514.
Crossref

Fabian Schwizer, Yasunori Okamoto, Tillmann Heinisch, Yifan Gu, Michela M. Pellizzoni, Vincent Lebrun, Raphael Reuter, Valentin Köhler, Jared C. Lewis & Thomas R. Ward. (2017) Artificial Metalloenzymes: Reaction Scope and Optimization Strategies. Chemical Reviews 118:1, pages 142-231.
Crossref

Sebastian C. Cosgrove, Agata Brzezniak, Scott P. France, Jeremy I. Ramsden, Juan Mangas-Sanchez, Sarah L. Montgomery, Rachel S. Heath & Nicholas J. Turner. 2018. Enzymes in Synthetic Biology. Enzymes in Synthetic Biology 131 149 .

Gheorghe-Doru Roiban, Marcelo Kern, Zhi Liu, Julia Hyslop, Pei Lyn Tey, Matthew S. Levine, Lydia S. Jordan, Kristin K. Brown, Timin Hadi, Leigh Anne F. Ihnken & Murray J. B. Brown. (2017) Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox. ChemCatChem 9:24, pages 4475-4479.
Crossref

Maike Lenz, Niels Borlinghaus, Leonie Weinmann & Bettina M. Nestl. (2017) Recent advances in imine reductase-catalyzed reactions. World Journal of Microbiology and Biotechnology 33:11.
Crossref

Godwin A. Aleku, Scott P. France, Henry Man, Juan Mangas-Sanchez, Sarah L. Montgomery, Mahima Sharma, Friedemann Leipold, Shahed Hussain, Gideon Grogan & Nicholas J. Turner. (2017) A reductive aminase from Aspergillus oryzae. Nature Chemistry 9:10, pages 961-969.
Crossref

Sebastian Roth, Andreas Präg, Cindy Wechsler, Marija Marolt, Sascha Ferlaino, Steffen Lüdeke, Nicolas Sandon, Dennis Wetzl, Hans Iding, Beat Wirz & Michael Müller. (2017) Extended Catalytic Scope of a Well-Known Enzyme: Asymmetric Reduction of Iminium Substrates by Glucose Dehydrogenase. ChemBioChem 18:17, pages 1703-1706.
Crossref

Zaira Maugeri & Dörte Rother. (2017) Reductive amination of ketones catalyzed by whole cell biocatalysts containing imine reductases (IREDs). Journal of Biotechnology 258, pages 167-170.
Crossref

Mahima SharmaJuan Mangas-SanchezNicholas J. TurnerGideon Grogan. (2017) NAD(P)H-Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application. Advanced Synthesis & Catalysis 359:12, pages 2011-2025.
Crossref

Hao Li, Ping Tian, Jian-He Xu & Gao-Wei Zheng. (2017) Identification of an Imine Reductase for Asymmetric Reduction of Bulky Dihydroisoquinolines. Organic Letters 19:12, pages 3151-3154.
Crossref

Maike Lenz, Philipp N. Scheller, Sven M. Richter, Bernhard Hauer & Bettina M. Nestl. (2017) Cultivation and purification of two stereoselective imine reductases from Streptosporangium roseum and Paenibacillus elgii. Protein Expression and Purification 133, pages 199-204.
Crossref

Juan Mangas-Sanchez, Scott P France, Sarah L Montgomery, Godwin A Aleku, Henry Man, Mahima Sharma, Jeremy I Ramsden, Gideon Grogan & Nicholas J Turner. (2017) Imine reductases (IREDs). Current Opinion in Chemical Biology 37, pages 19-25.
Crossref

Koichi Mitsukura & Toyokazu Yoshida. 2017. Future Directions in Biocatalysis. Future Directions in Biocatalysis 97 117 .

Philipp N. Scheller & Bettina M. Nestl. (2016) The biochemical characterization of three imine-reducing enzymes from Streptosporangium roseum DSM43021, Streptomyces turgidiscabies and Paenibacillus elgii. Applied Microbiology and Biotechnology 100:24, pages 10509-10520.
Crossref

Kathleen M. Meneely, Trey A. Ronnebaum, Andrew P. Riley, Thomas E. Prisinzano & Audrey L. Lamb. (2016) Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis. Biochemistry 55:38, pages 5423-5433.
Crossref

Tillmann Heinisch & Thomas R. Ward. (2016) Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Challenges and Opportunities. Accounts of Chemical Research 49:9, pages 1711-1721.
Crossref

Zaira Maugeri & Dörte Rother. (2016) Application of Imine Reductases (IREDs) in Micro‐Aqueous Reaction Systems. Advanced Synthesis & Catalysis 358:17, pages 2745-2750.
Crossref

Henrike Brundiek & Matthias Höhne. 2016. Applied Biocatalysis: From Fundamental Science to Industrial Applications. Applied Biocatalysis: From Fundamental Science to Industrial Applications 199 218 .

Martin Gand, Christian Thöle, Hubertus Müller, Henrike Brundiek, Ghader Bashiri & Matthias Höhne. (2016) A NADH-accepting imine reductase variant: Immobilization and cofactor regeneration by oxidative deamination. Journal of Biotechnology 230, pages 11-18.
Crossref

Michihiko Kataoka, Takuya Miyakawa, Sakayu Shimizu & Masaru Tanokura. (2016) Enzymes useful for chiral compound synthesis: structural biology, directed evolution, and protein engineering for industrial use. Applied Microbiology and Biotechnology 100:13, pages 5747-5757.
Crossref

Dennis Wetzl, Martin Gand, Alfred Ross, Hubertus Müller, Philipp Matzel, Steven P. Hanlon, Michael Müller, Beat Wirz, Matthias Höhne & Hans Iding. (2016) Asymmetric Reductive Amination of Ketones Catalyzed by Imine Reductases. ChemCatChem 8:12, pages 2023-2026.
Crossref

Scott P. France, Shahed Hussain, Andrew M. Hill, Lorna J. Hepworth, Roger M. Howard, Keith R. Mulholland, Sabine L. Flitsch & Nicholas J. Turner. (2016) One-Pot Cascade Synthesis of Mono- and Disubstituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA), and Imine Reductase (IRED) Biocatalysts. ACS Catalysis 6:6, pages 3753-3759.
Crossref

Godwin A. Aleku, Henry Man, Scott P. France, Friedemann Leipold, Shahed Hussain, Laura Toca-Gonzalez, Rebecca Marchington, Sam Hart, Johan P. Turkenburg, Gideon Grogan & Nicholas J. Turner. (2016) Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis . ACS Catalysis 6:6, pages 3880-3889.
Crossref

Silvia Fademrecht, Philipp N. Scheller, Bettina M. Nestl, Bernhard Hauer & Jürgen Pleiss. (2016) Identification of imine reductase-specific sequence motifs. Proteins: Structure, Function, and Bioinformatics 84:5, pages 600-610.
Crossref

Iustina Slabu, James L. Galman, Nicholas J. Weise, Richard C. Lloyd & Nicholas J. Turner. (2016) Putrescine Transaminases for the Synthesis of Saturated Nitrogen Heterocycles from Polyamines. ChemCatChem 8:6, pages 1038-1042.
Crossref

Gideon GroganNicholas J. Turner. (2016) InspIRED by Nature: NADPH-Dependent Imine Reductases (IREDs) as Catalysts for the Preparation of Chiral Amines. Chemistry - A European Journal 22:6, pages 1900-1907.
Crossref

Hao Li, Guang-Xiang Zhang, Liu-Mei Li, Yu-Shi Ou, Ming-Yang Wang, Chun-Xiu Li, Gao-Wei Zheng & Jian-He Xu. (2016) A Novel ( R )-Imine Reductase from Paenibacillus lactis for Asymmetric Reduction of 3 H -Indoles . ChemCatChem 8:4, pages 724-727.
Crossref

Rachel S. Heath, Marta Pontini, Shahed Hussain & Nicholas J. Turner. (2016) Combined Imine Reductase and Amine Oxidase Catalyzed Deracemization of Nitrogen Heterocycles. ChemCatChem 8:1, pages 117-120.
Crossref

Maria F. Villegas-Torres, R. Julio Martinez-Torres, Armando Cázares-Körner, Helen Hailes, Frank Baganz & John Ward. (2015) Multi-step biocatalytic strategies for chiral amino alcohol synthesis. Enzyme and Microbial Technology 81, pages 23-30.
Crossref

Philipp N. Scheller, Maike Lenz, Stephan C. Hammer, Bernhard Hauer & Bettina M. Nestl. (2015) Imine Reductase-Catalyzed Intermolecular Reductive Amination of Aldehydes and Ketones. ChemCatChem 7:20, pages 3239-3242.
Crossref

Renata Sigrist, Bruna Zucoloto da Costa, Anita Jocelyne Marsaioli & Luciana Gonzaga de Oliveira. (2015) Nature-inspired enzymatic cascades to build valuable compounds. Biotechnology Advances 33:5, pages 394-411.
Crossref

Dennis Wetzl, Marco Berrera, Nicolas Sandon, Dan Fishlock, Martin Ebeling, Michael Müller, Steven Hanlon, Beat Wirz & Hans Iding. (2015) Expanding the Imine Reductase Toolbox by Exploring the Bacterial Protein-Sequence Space. ChemBioChem 16:12, pages 1749-1756.
Crossref

Joerg H. Schrittwieser, Stefan Velikogne & Wolfgang Kroutil. (2015) Biocatalytic Imine Reduction and Reductive Amination of Ketones. Advanced Synthesis & Catalysis 357:8, pages 1655-1685.
Crossref

Hao Li, Zheng-Jiao Luan, Gao-Wei Zheng & Jian-He Xu. (2015) Efficient Synthesis of Chiral Indolines using an Imine Reductase from Paenibacillus lactis . Advanced Synthesis & Catalysis 357:8, pages 1692-1696.
Crossref

Henry Man, Elizabeth Wells, Shahed Hussain, Friedemann Leipold, Sam Hart, Johan P. Turkenburg, Nicholas J. Turner & Gideon Grogan. (2015) Structure, Activity and Stereoselectivity of NADPH‐Dependent Oxidoreductases Catalysing the S ‐Selective Reduction of the Imine Substrate 2‐Methylpyrroline . ChemBioChem 16:7, pages 1052-1059.
Crossref

Shahed Hussain, Friedemann Leipold, Henry Man, Elizabeth Wells, Scott P. France, Keith R. Mulholland, Gideon Grogan & Nicholas J. Turner. (2015) An ( R )‐Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines . ChemCatChem 7:4, pages 579-583.
Crossref

M. Gand, H. Müller, R. Wardenga & M. Höhne. (2014) Characterization of three novel enzymes with imine reductase activity. Journal of Molecular Catalysis B: Enzymatic 110, pages 126-132.
Crossref

V P Ananikov, L L Khemchyan, Yu V Ivanova, V I Bukhtiyarov, A M Sorokin, I P Prosvirin, S Z Vatsadze, A V Medved'ko, V N Nuriev, A D Dilman, V V Levin, I V Koptyug, K V Kovtunov, V V Zhivonitko, V A Likholobov, A V Romanenko, P A Simonov, V G Nenajdenko, O I Shmatova, V M Muzalevskiy, M S Nechaev, A F Asachenko, O S Morozov, P B Dzhevakov, S N Osipov, D V Vorobyeva, M A Topchiy, M A Zotova, S A Ponomarenko, O V Borshchev, Yu N Luponosov, A A Rempel, A A Valeeva, A Yu Stakheev, O V Turova, I S Mashkovsky, S V Sysolyatin, V V Malykhin, G A Bukhtiyarova, A O Terent'ev & I B Krylov. (2014) Development of new methods in modern selective organic synthesis: preparation of functionalized molecules with atomic precision. Russian Chemical Reviews 83:10, pages 885-985.
Crossref

Philipp N. Scheller, Silvia Fademrecht, Sebastian Hofelzer, Jürgen Pleiss, Friedemann Leipold, Nicholas J. Turner, Bettina M. Nestl & Bernhard Hauer. (2014) Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases. ChemBioChem 15:15, pages 2201-2204.
Crossref

Tobias Huber, Lisa Schneider, Andreas Präg, Stefan Gerhardt, Oliver Einsle & Michael Müller. (2014) Direct Reductive Amination of Ketones: Structure and Activity of S ‐Selective Imine Reductases from Streptomyces . ChemCatChem 6:8, pages 2248-2252.
Crossref

Hannes Kohls, Fabian Steffen-Munsberg & Matthias Höhne. (2014) Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis. Current Opinion in Chemical Biology 19, pages 180-192.
Crossref

Diego Ghislieri & Nicholas J. Turner. (2013) Biocatalytic Approaches to the Synthesis of Enantiomerically Pure Chiral Amines. Topics in Catalysis 57:5, pages 284-300.
Crossref

Daniela Gamenara & Pablo Domínguez de María. (2014) Enantioselective imine reduction catalyzed by imine reductases and artificial metalloenzymes. Org. Biomol. Chem. 12:19, pages 2989-2992.
Crossref

N.J. Turner. 2014. Comprehensive Organic Synthesis II. Comprehensive Organic Synthesis II 328 338 .

Friedemann Leipold, Shahed Hussain, Diego Ghislieri & Nicholas J. Turner. (2013) Asymmetric Reduction of Cyclic Imines Catalyzed by a Whole‐Cell Biocatalyst Containing an ( S )‐Imine Reductase . ChemCatChem 5:12, pages 3505-3508.
Crossref

Elena Fernández-Álvaro & Pablo Domínguez de María. 2013. Synthetic Methods for Biologically Active Molecules. Synthetic Methods for Biologically Active Molecules 27 47 .

Roland Wohlgemuth. 2013. Synthetic Methods for Biologically Active Molecules. Synthetic Methods for Biologically Active Molecules 1 25 .

Koichi Mitsukura, Tatsuya Kuramoto, Toyokazu Yoshida, Norihiro Kimoto, Hiroaki Yamamoto & Toru Nagasawa. (2012) A NADPH-dependent (S)-imine reductase (SIR) from Streptomyces sp. GF3546 for asymmetric synthesis of optically active amines: purification, characterization, gene cloning, and expression. Applied Microbiology and Biotechnology 97:18, pages 8079-8086.
Crossref

María Rodríguez-Mata, Annika Frank, Elizabeth Wells, Friedemann Leipold, Nicholas J. Turner, Sam Hart, Johan P. Turkenburg & Gideon Grogan. (2013) Structure and Activity of NADPH-Dependent Reductase Q1EQE0 from Streptomyces kanamyceticus , which Catalyses the R -Selective Reduction of an Imine Substrate . ChemBioChem 14:11, pages 1372-1379.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Purification and Characterization of a Novel (R)-Imine Reductase from Streptomyces sp. GF3587

Articles from other publishers (115)

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Purification and Characterization of a Novel (R)-Imine Reductase from Streptomyces sp. GF3587

Citations (115)

Articles from other publishers (115)

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date