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Bioscience, Biotechnology, and Biochemistry Volume 76, 2012 - Issue 6
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Original Articles

A Novel Reductase from Candida albicans for the Production of Ethyl (S)-4-Chloro-3-hydroxybutanoate

Mingdong ANCollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
,
Ping CAICollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
,
Ming YANCollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
,
Ning HAOCollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
,
Shanshan WANGCollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
,
Huan LIUCollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
,
Yan LICollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
&
Lin XUCollege of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology
 show all
Pages 1210-1212 | Received 07 Feb 2012, Accepted 12 Mar 2012, Published online: 22 May 2014

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Ping Cai, Mingdong An, Sheng Xu, Ming Yan, Ning Hao, Yan Li & Lin Xu. (2015) Asymmetric synthesis of (S)-4-chloro-3-hydroxybutanoate by sorbose reductase from Candida albicans with two co-existing recombinant Escherichia coli strains. Bioscience, Biotechnology, and Biochemistry 79:7, pages 1090-1093.
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Articles from other publishers (8)

Anirudh P. Shanbhag. (2023) Stairway to Stereoisomers: Engineering Short‐ and Medium‐Chain Ketoreductases To Produce Chiral Alcohols. ChemBioChem 24:6.
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Zhen Zhang, Zichen Yu, Jinduo Wang, Yifa Yu, Lanxiao Li, Pengjie Sun, Xiaoguang Fan & Qingyang Xu. (2022) Metabolic engineering of Escherichia coli for efficient production of L-5-hydroxytryptophan from glucose. Microbial Cell Factories 21:1.
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Yi-Hao Zhu, Cai-Yun Liu, Sha Cai, Li-Bin Guo, In-Won Kim, Vipin C. Kalia, Jung-Kul Lee & Ye-Wang Zhang. (2019) Cloning, Expression and Characterization of a Highly Active Alcohol Dehydrogenase for Production of Ethyl (S)-4-Chloro-3-Hydroxybutyrate. Indian Journal of Microbiology 59:2, pages 225-233.
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Zhi‐Qiang Liu, Zhong‐Liang Hu, Xiao‐Jian Zhang, Xiao‐Ling Tang, Feng Cheng, Ya‐Ping Xue, Ya‐Jun Wang, Lin Wu, Dan‐Kai Yao, Yi‐Teng Zhou & Yu‐Guo Zheng. (2017) Large‐scale synthesis of tert‐ butyl ( 3R,5S )‐6‐chloro‐3,5‐dihydroxyhexanoate by a stereoselective carbonyl reductase with high substrate concentration and product yield . Biotechnology Progress 33:3, pages 612-620.
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Qin Xu, Wei-Yi Tao, He Huang & Shuang Li. (2016) Highly efficient synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by a novel carbonyl reductase from Yarrowia lipolytica and using mannitol or sorbitol as cosubstrate. Biochemical Engineering Journal 106, pages 61-67.
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Zhi-Qiang Liu, Jing-Jing Ye, Zhen-Yang Shen, Hua-Bin Hong, Jian-Bo Yan, Yi Lin, Zheng-Xu Chen, Yu-Guo Zheng & Yin-Chu Shen. (2014) Upscale production of ethyl (S)-4-chloro-3-hydroxybutanoate by using carbonyl reductase coupled with glucose dehydrogenase in aqueous-organic solvent system. Applied Microbiology and Biotechnology 99:5, pages 2119-2129.
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Zhong-Yu You, Zhi-Qiang Liu & Yu-Guo Zheng. (2013) Characterization of a newly synthesized carbonyl reductase and construction of a biocatalytic process for the synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate with high space-time yield. Applied Microbiology and Biotechnology 98:4, pages 1671-1680.
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Ping Cai, Mingdong An, Lin Xu, Sheng Xu, Ning Hao, Yan Li, Kai Guo & Ming Yan. (2012) Development of a substrate-coupled biocatalytic process driven by an NADPH-dependent sorbose reductase from Candida albicans for the asymmetric reduction of ethyl 4-chloro-3-oxobutanoate. Biotechnology Letters 34:12, pages 2223-2227.
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