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Original Articles

Synthesis of 2-O-Methyl Ether and 1-Carboxamide Derivatives of (2R,3S)-3-Isopropylmalic Acid and Their Interaction with Thermophilic 3-Isopropylmalate Dehydrogenase

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Pages 870-873 | Received 12 Oct 1993, Published online: 12 Jun 2014

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Masaaki FUJITA, Hideyuki TAMEGAI, Tadashi EGUCHI & Katsumi KAKINUMA. (2001) Novel Substrate Specificity of Designer 3-Isopropylmalate Dehydrogenase Derived from Thermus thermophilus HB8. Bioscience, Biotechnology, and Biochemistry 65:12, pages 2695-2700.
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Akira CHIBA, Tadashi EGUCHI, Tairo OSHIMA & Katsumi KAKINUMA. (1999) Coenzyme Activity of NAD Analogs for 3-Isopropylmalate Dehydrogenase from Thermus thermophilus HB8. Bioscience, Biotechnology, and Biochemistry 63:9, pages 1647-1649.
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Articles from other publishers (9)

Eriko Nango, Takashi Yamamoto, Takashi Kumasaka & Tadashi Eguchi. (2009) Crystal structure of 3-isopropylmalate dehydrogenase in complex with NAD+ and a designed inhibitor. Bioorganic & Medicinal Chemistry 17:22, pages 7789-7794.
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Masaaki Fujita, Yumiko Toyooka, Hideyuki Tamegai, Tadashi Eguchi & Katsumi Kakinuma. (2000) Arg-94 is crucial to the catalysis of 3-isopropylmalate dehydrogenase from Thermus thermophilus HB8. Journal of Molecular Catalysis B: Enzymatic 9:4-6, pages 149-155.
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Yoko Hayashi-Iwasaki & Tairo Oshima. 2000. Branched-Chain Amino Acids, Part B. Branched-Chain Amino Acids, Part B 301 322 .
Akira Chiba, Noriko Arai, Tadashi Eguchi & Katsumi Kakinuma. (1999) 3-Isopropylidenemalic Acid: A Mechanism-based Inhibitor of 3-Isopropylmalate Dehydrogenase. Chemistry Letters 28:12, pages 1313-1314.
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Akira Chiba, Tetsuya Aoyama, Rieko Suzuki, Tadashi Eguchi, Tairo Oshima & Katsumi Kakinuma. (1999) Synthetic and Mechanistic Studies of (2 R ,3 S )-3-Vinylmalic Acid as a Mechanism-Based Inhibitor of 3-Isopropylmalate Dehydrogenase . The Journal of Organic Chemistry 64:17, pages 6159-6165.
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Akira Chiba, Tadashi Eguchi, Tairo Oshima & Katsumi Kakinuma. (1999) Synthesis of cyclopropane substrate analog for 3-isopropylmalate dehydrogenase and its mechanism-based inhibition. Tetrahedron 55:10, pages 2927-2936.
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Akira Chiba, Tadashi Eguchi, Tairo Oshima & Katsumi Kakinuma. (1997) Synthesis of conformationally restricted substrate analogs and their interaction with 3-isopropylmalate dehydrogenase derived from Thermus thermophilus. Tetrahedron 53:10, pages 3537-3544.
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Masashi Kishida, Ta-i Eguchi & Katsumi Kakinuma. (1996) Remote asymmetric induction observed in the alkylation of propionate attached to a carbohydrate template. Tetrahedron Letters 37:12, pages 2061-2062.
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Yumiko Toyooka, Toshihiro Matsuzawa, Tadashi Eguchi & Katsumi Kakinuma. (1995) NADH mimics on diacetone-d-glucose: Stereoselective biomimetic reduction of benzoylformate and interpretation of chirality transfer deduced by molecular orbital approach. Tetrahedron 51:23, pages 6459-6474.
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