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Original Articles

Flavonoids Inhibit Cell Growth and Induce Apoptosis in B16 Melanoma 4A5 Cells

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Pages 1813-1820 | Received 28 Jan 2000, Accepted 24 Apr 2000, Published online: 22 May 2014

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Mariana Teixeira Santos Figueiredo Salgado, Estela Fernandes e Silva, Mariana Amaral do Nascimento, Alessandra Costa Lopes, Luciana Souza de Paiva & Ana Paula de Souza Votto. (2023) Potential Therapeutic Targets of Quercetin in the Cutaneous Melanoma Model and Its Cellular Regulation Pathways: A Systematic Review. Nutrition and Cancer 75:9, pages 1687-1709.
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Hua Qiao, Xiaoyun Zhang, Ting Wang, Li Liang, Wei Chang & Huxiong Xia. (2014) Pharmacokinetics, biodistribution and bioavailability of isoliquiritigenin after intravenous and oral administration. Pharmaceutical Biology 52:2, pages 228-236.
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SHAMS TABREZ, MEDHA PRIYADARSHINI, MARYAM UROOJ, SHAZI SHAKIL, GHULAM Md ASHRAF, MOHD SHAHNAWAZ KHAN, MOHAMMAD AMJAD KAMAL, QAMRE ALAM, NASIMUDEENR. JABIR, ADEL MOHAMMAD ABUZENADAH, ADEELG. A. CHAUDHARY & GHAZI ABDULLAH DAMANHOURI. (2013) Cancer Chemoprevention by Polyphenols and Their Potential Application as Nanomedicine. Journal of Environmental Science and Health, Part C 31:1, pages 67-98.
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Zhihua Cui, E. Song, Dan-Ning Hu, Min Chen, Richard Rosen & Steven A. McCormick. (2012) Butein Induces Apoptosis in Human Uveal Melanoma Cells Through Mitochondrial Apoptosis Pathway. Current Eye Research 37:8, pages 730-739.
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Xuan Yuan, Bo Zhang, Na Chen, Xiao-Yu Chen, Liang-Liang Liu, Qiu-Sheng Zheng & Zhi-Ping Wang. (2012) Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells. Journal of Asian Natural Products Research 14:8, pages 789-798.
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Kenji OHGUCHI, Yukihiro AKAO & Yoshinori NOZAWA. (2006) Stimulation of Melanogenesis by the Citrus Flavonoid Naringenin in Mouse B16 Melanoma Cells. Bioscience, Biotechnology, and Biochemistry 70:6, pages 1499-1501.
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Wen-Xin Li, Cheng-Bin Cui, Bing Cai, Hai-Yan Wang & Xin-Sheng Yao. (2005) Flavonoids from Vitex trifolia L. inhibit cell cycle progression at G2/M phase and induce apoptosis in mammalian cancer cells. Journal of Asian Natural Products Research 7:4, pages 615-626.
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Hyun-Mi Kang, Jong-Han Kim, Mi-Young Lee, Kwang-Hee Son, Deok Cho Yang, Nam-In Baek & Byoung-Mog Kwon. (2004) Relationship Between Flavonoid Structure and Inhibition of Farnesyl Protein Transferase. Natural Product Research 18:4, pages 349-356.
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Hiroshige Hibasami, Hideo Esaki, Tomoko Kataoka, Sachiko Takaue & Shunro Kawakishi. (2004) Human Stomach Cancer Cells Undergo Apoptosis by Genistein, But Not Other Genistein-and Daidzein-Related Compounds. Journal of Herbs, Spices & Medicinal Plants 10:4, pages 39-48.
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Crossref
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Cuilan Hou, Wenguang Li, Zengyou Li, Jing Gao, Zhenjie Chen, Xiqiong Zhao, Yaya Yang, Xiaoyu Zhang & Yong Song. (2017) Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism. Oxidative Medicine and Cellular Longevity 2017, pages 1-11.
Crossref
Sean M. Bugel, Josephine A. Bonventre & Robert L. Tanguay. (2016) Comparative Developmental Toxicity of Flavonoids Using an Integrative Zebrafish System. Toxicological Sciences 154:1, pages 55-68.
Crossref
Dong-Sung Lee & Gil-Saeng Jeong. (2016) Butein provides neuroprotective and anti-neuroinflammatory effects through Nrf2/ARE-dependent haem oxygenase 1 expression by activating the PI3K/Akt pathway. British Journal of Pharmacology 173:19, pages 2894-2909.
Crossref
Sharad Verma, Sukriti Goyal, Salma Jamal, Aditi Singh & Abhinav Grover. (2016) Hsp90: Friends, clients and natural foes. Biochimie 127, pages 227-240.
Crossref
Ramesh Santhanam, Syahida Ahmad, Faridah Abas, Intan Safinar Ismail, Yaya Rukayadi, Muhammad Tayyab Akhtar & Khozirah Shaari. (2016) Bioactive Constituents of Zanthoxylum rhetsa Bark and Its Cytotoxic Potential against B16-F10 Melanoma Cancer and Normal Human Dermal Fibroblast (HDF) Cell Lines. Molecules 21:6, pages 652.
Crossref
Peijie Chen, Peiming Bai, Guangcheng Luo, Hanzhong Su, Ruixiong Shen, Ziming Liu, Nangen Zhang, Lin Fang & Chunxiao Liu. (2016) Role of Anti-apoptotic Activity of Antioxidants in Conferring Protection Against Prostate Cancer. International Journal of Pharmacology 12:4, pages 304-316.
Crossref
Tran Dang Xuan & Tran Dang Khanh. (2016) Chemistry and pharmacology of Bidens pilosa: an overview. Journal of Pharmaceutical Investigation 46:2, pages 91-132.
Crossref
Yasuharu Watanabe, Yoshinori Nagai, Hiroe Honda, Naoki Okamoto, Seiji Yamamoto, Takeru Hamashima, Yoko Ishii, Miyako Tanaka, Takayoshi Suganami, Masakiyo Sasahara, Kensuke Miyake & Kiyoshi Takatsu. (2016) Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice. Scientific Reports 6:1.
Crossref
Chun-Lin Ye & Yi-Feng Lai. (2014) 2′,4′-Dihydroxy-6′-methoxy-3′,5′-dimethylchalcone, from buds of Cleistocalyx operculatus, induces apoptosis in human hepatoma SMMC-7721 cells through a reactive oxygen species-dependent mechanism. Cytotechnology 68:2, pages 331-341.
Crossref
Zsuzsanna Rozmer & Pál Perjési. (2014) Naturally occurring chalcones and their biological activities. Phytochemistry Reviews 15:1, pages 87-120.
Crossref
Rajeshwari H. Patil, R. L. Babu, M. Naveen Kumar, K. M. Kiran Kumar, Shubha M. Hegde, Rashmi Nagesh, Govindarajan T. Ramesh & S. Chidananda Sharma. (2015) Anti-Inflammatory Effect of Apigenin on LPS-Induced Pro-Inflammatory Mediators and AP-1 Factors in Human Lung Epithelial Cells. Inflammation 39:1, pages 138-147.
Crossref
Alak Manna, Subrata Chattopadhyay & Mitali Chatterjee. 2016. 81 129 .
Ziwei Song, Muthu K. Shanmugam, Hanry Yu & Gautam Sethi. 2016. Anti-inflammatory Nutraceuticals and Chronic Diseases. Anti-inflammatory Nutraceuticals and Chronic Diseases 419 433 .
Sang‑Mi Woo, Youn Choi, Ah Kim, Sung‑Gook Cho & Seong‑Gyu Ko. (2015) p53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells. Molecular Medicine Reports.
Crossref
Ganesan Padmavathi, Sivakumar Raju Rathnakaram, Javadi Monisha, Devivasha Bordoloi, Nand Kishor Roy & Ajaikumar B. Kunnumakkara. (2015) Potential of butein, a tetrahydroxychalcone to obliterate cancer. Phytomedicine 22:13, pages 1163-1171.
Crossref
Pritha Dasgupta & Sumita Sengupta (Bandyopadhyay). (2015) Role of diallyl disulfide-mediated cleavage of c-Myc and Sp-1 in the regulation of telomerase activity in human lymphoma cell line U937. Nutrition 31:7-8, pages 1031-1037.
Crossref
Mi Jin Kim, Taraman Kadayat, Yeon Ji Um, Tae Cheon Jeong, Eung-Seok Lee & Pil-Hoon Park. (2015) Inhibitory Effect of 3-(4-Hydroxyphenyl)-1-(thiophen-2-yl) prop-2-en-1-one, a Chalcone Derivative on MCP-1 Expression in Macrophages via Inhibition of ROS and Akt Signaling. Biomolecules & Therapeutics 23:2, pages 119-127.
Crossref
Ruchi Badoni Semwal, Deepak Kumar Semwal, Sandra Combrinck & Alvaro Viljoen. (2015) Butein: From ancient traditional remedy to modern nutraceutical. Phytochemistry Letters 11, pages 188-201.
Crossref
Neamt H. A. Osman, Usama Z. Said, Ahmed M. El-Waseef & Esraa S. A. Ahmed. (2014) Luteolin supplementation adjacent to aspirin treatment reduced dimethylhydrazine-induced experimental colon carcinogenesis in rats. Tumor Biology 36:2, pages 1179-1190.
Crossref
Janmejai K. Srivastava & Sanjay Gupta. 2015. Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults. Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults 171 183 .
Hiroe Honda, Yoshinori Nagai, Takayuki Matsunaga, Naoki Okamoto, Yasuharu Watanabe, Koichi Tsuneyama, Hiroaki Hayashi, Isao Fujii, Masashi Ikutani, Yoshikatsu Hirai, Atsushi Muraguchi & Kiyoshi Takatsu. (2014) Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation. Journal of Leukocyte Biology 96:6, pages 1087-1100.
Crossref
Júlio César Conceição Filho, André Lúcio Franceschini Sarria, Amanda Blanque Becceneri, Angelina Maria Fuzer, Jaqueline Raquel Batalhão, Caio Marcio Paranhos da Silva, Rose Maria Carlos, Paulo Cezar Vieira, João Batista Fernandes & Márcia Regina Cominetti. (2014) Copper (II) and 2,2′-Bipyridine Complexation Improves Chemopreventive Effects of Naringenin against Breast Tumor Cells. PLoS ONE 9:9, pages e107058.
Crossref
Dong-Sung Lee, Kyoung-Su Kim, Wonmin Ko, Bin Li, Samell Keo, Gil-Saeng Jeong, Hyuncheol Oh & Youn-Chul Kim. (2014) The Neoflavonoid Latifolin Isolated from MeOH Extract of Dalbergia odorifera Attenuates Inflammatory Responses by Inhibiting NF-κB Activation via Nrf2-Mediated Heme Oxygenase-1 Expression . Phytotherapy Research 28:8, pages 1216-1223.
Crossref
Young Ho Seo & Ju Hui Jeong. (2014) Synthesis of Butein Analogues and their Anti-proliferative Activity Against Gefitinib-resistant Non-small Cell Lung Cancer (NSCLC) through Hsp90 Inhibition. Bulletin of the Korean Chemical Society 35:5, pages 1294-1298.
Crossref
Syaefudin .W.T. Wahyuni, I.M. Artika & Sulistiyani .. (2014) Antioxidant Activity of Flavonoid from Guazuma ulmifolia Lamk. Leaves and Apoptosis Induction in Yeast Cells. Journal of Biological Sciences 14:4, pages 305-310.
Crossref
P. Kumar, Y.E. Choonara, G. Modi, D. Naidoo & V. Pillay. (2014) Cur(Que)min: A neuroactive permutation of Curcumin and Quercetin for treating spinal cord injury. Medical Hypotheses 82:4, pages 437-441.
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Murtala B. Abubakar, Wan Zaidah Abdullah, Siti Amrah Sulaiman & Boon Suen Ang. (2014) Polyphenols as Key Players for the Antileukaemic Effects of Propolis. Evidence-Based Complementary and Alternative Medicine 2014, pages 1-11.
Crossref
P. J. Bindu, K. M. Mahadevan, T. R. Ravikumar Naik & B. G. Harish. (2014) Synthesis, DNA binding, docking and photocleavage studies of quinolinyl chalcones. Med. Chem. Commun. 5:11, pages 1708-1717.
Crossref
Donghua Qian. (2013) Butein induces cell apoptosis and inhibition of cyclooxygenase‑2 expression in A549 lung cancer cells. Molecular Medicine Reports.
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Xiaowei Zhang, Pingping Shang, Fang Qin, Qin Zhou, Boyan Gao, Haiqiu Huang, Haisha Yang, Haiming Shi & Liangli (Lucy) Yu. (2013) Chemical composition and antioxidative and anti-inflammatory properties of ten commercial mung bean samples. LWT - Food Science and Technology 54:1, pages 171-178.
Crossref
Viduranga Waisundara & Lee Yian Hoon. (2013) A Comparative Study on the Antioxidant Activity of Commonly Used South Asian Herbs. Journal of Traditional and Complementary Medicine 3:4, pages 263-267.
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Crossref
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Naghma KhanVaqar M. AdhamiFarrukh AfaqHasan Mukhtar. (2012) Butein Induces Apoptosis and Inhibits Prostate Tumor Growth In Vitro and In Vivo . Antioxidants & Redox Signaling 16:11, pages 1195-1204.
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YA-HUI CHEN, CHI-WEI YEH, HUI-CHEN LO, SHIH-LI SU, YOU-CHENG HSEU & LI-SUNG HSU. (2012) Generation of reactive oxygen species mediates butein-induced apoptosis in neuroblastoma cells. Oncology Reports 27:4, pages 1233-1237.
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Bokyung Sung, Sung‐Gook Cho, Mingyao Liu & Bharat B. Aggarwal. (2011) Butein, a tetrahydroxychalcone, suppresses cancer‐induced osteoclastogenesis through inhibition of receptor activator of nuclear factor‐kappaB ligand signaling. International Journal of Cancer 129:9, pages 2062-2072.
Crossref
Glaucio Valdameri, Marina Trombetta-Lima, Paulo R. Worfel, Amanda R.A. Pires, Glaucia R. Martinez, Guilhermina R. Noleto, Silvia M.S.C. Cadena, Mari C. Sogayar, Sheila M.B. Winnischofer & Maria E.M. Rocha. (2011) Involvement of catalase in the apoptotic mechanism induced by apigenin in HepG2 human hepatoma cells. Chemico-Biological Interactions 193:2, pages 180-189.
Crossref
Chia-Yu Ma, Wei-Ting Ji, Fu-Shin Chueh, Jai-Sing Yang, Po-Yuan Chen, Chien-Chih Yu & Jing-Gung Chung. (2011) Butein Inhibits the Migration and Invasion of SK-HEP-1 Human Hepatocarcinoma Cells through Suppressing the ERK, JNK, p38, and uPA Signaling Multiple Pathways. Journal of Agricultural and Food Chemistry 59:16, pages 9032-9038.
Crossref
Peramaiyan Rajendran, Tina H. Ong, Luxi Chen, Feng Li, Muthu K. Shanmugam, Shireen Vali, Taher Abbasi, Shweta Kapoor, Ashish Sharma, Alan Prem Kumar, Kam M. Hui & Gautam Sethi. (2011) Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo . Clinical Cancer Research 17:6, pages 1425-1439.
Crossref
Vivek R. Yadav, Sahdeo Prasad, Bokyung Sung & Bharat B. Aggarwal. (2011) The role of chalcones in suppression of NF-κB-mediated inflammation and cancer. International Immunopharmacology 11:3, pages 295-309.
Crossref
K Garg Neeraj, Mangal Sharad, Sahu Tejram, Mehta Abhinav, P Vyas Suresh & K Tyagi Rajeev. (2011) Evaluation of anti–apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide. Asian Pacific Journal of Tropical Biomedicine 1:1, pages 57-63.
Crossref
Gil-Saeng Jeong, Dong-Sung Lee, Mi-Young Song, Byung-Hyun Park, Dae-Gill Kang, Ho-Sub Lee, Kang-Beom Kwon & Youn-Chul Kim. (2011) Butein from <i>Rhus verniciflua</i> Protects Pancreatic &beta; Cells against Cytokine-Induced Toxicity Mediated by Inhibition of Nitric Oxide Formation. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 34:1, pages 97-102.
Crossref
Linling Li, Hua Cheng, Jianying Peng & Shuiyuan Cheng. (2010) Construction of a plant expression vector of chalcone synthase gene of Ginkgo biloba L. and its genetic transformation into tobacco. Frontiers of Agriculture in China 4:4, pages 456-462.
Crossref
Zhuohong Xie, Wei Liu, Haiqiu Huang, Margaret Slavin, Yang Zhao, Monica Whent, Jessica Blackford, Herman Lutterodt, Huiping Zhou, Pei Chen, Thomas T. Y. Wang, Shaoke Wang & Liangli (Lucy) Yu. (2010) Chemical Composition of Five Commercial Gynostemma pentaphyllum Samples and Their Radical Scavenging, Antiproliferative, and Anti-inflammatory Properties. Journal of Agricultural and Food Chemistry 58:21, pages 11243-11249.
Crossref
Angeline Wei Ling Chua, Hui Sin Hay, Peramaiyan Rajendran, Muthu K. Shanmugam, Feng Li, Pradeep Bist, Evelyn S.C. Koay, Lina H.K. Lim, Alan Prem Kumar & Gautam Sethi. (2010) Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells. Biochemical Pharmacology 80:10, pages 1553-1562.
Crossref
Dong-Oh Moon, Yung Hyun Choi, Sung-Kwon Moon, Wun-Jae Kim & Gi-Young Kim. (2010) Butein suppresses the expression of nuclear factor-kappa B-mediated matrix metalloproteinase-9 and vascular endothelial growth factor in prostate cancer cells. Toxicology in Vitro 24:7, pages 1927-1934.
Crossref
Grace Tak Yi Lau & Lai K. Leung. (2010) The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines. Food and Chemical Toxicology 48:10, pages 3022-3027.
Crossref
Dong-Oh Moon, Mun-Ock Kim, Yung Hyun Choi & Gi-Young Kim. (2010) Butein Sensitizes Human Hepatoma Cells to TRAIL-Induced Apoptosis via Extracellular Signal-Regulated Kinase/Sp1–Dependent DR5 Upregulation and NF-κB Inactivation. Molecular Cancer Therapeutics 9:6, pages 1583-1595.
Crossref
Sanjeev Shukla & Sanjay Gupta. (2010) Apigenin: A Promising Molecule for Cancer Prevention. Pharmaceutical Research 27:6, pages 962-978.
Crossref
Dong-Oh Moon, Mun-Ock Kim, Yung Hyun Choi, Jin Won Hyun, Weon Young Chang & Gi-Young Kim. (2010) Butein induces G2/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation. Cancer Letters 288:2, pages 204-213.
Crossref
Kathy Ka-Wai Auyeung & Joshua Ka-Shun Ko. (2009) Novel herbal flavonoids promote apoptosis but differentially induce cell cycle arrest in human colon cancer cell. Investigational New Drugs 28:1, pages 1-13.
Crossref
Yoon Geon KimSabarish RamachandranDong-chul KimYoung Bin HongEun Ha KimSang-Hoon KwonSo-Jin ShinSoon-Do ChaInsoo BaeChi-Heum Cho. (2010) Isoliquiritigenin inhibited cell proliferation and triggered apoptosis in human endometrial cancer cell line. Journal of Women's Medicine 3:3, pages 89.
Crossref
Sanjeev Shukla & Sanjay Gupta. 2010. Bioactive Foods in Promoting Health. Bioactive Foods in Promoting Health 663 689 .
Guy G. Chabot, Yasmine S. Touil, Minh Hien Pham & Daniel Dauzonne. 2010. Alternative and Complementary Therapies for Cancer. Alternative and Complementary Therapies for Cancer 583 612 .
El-Shaimaa A. Arafa, Qianzheng Zhu, Bassant M. Barakat, Gulzar Wani, Qun Zhao, Mohamed A. El-Mahdy & Altaf A. Wani. (2009) Tangeretin Sensitizes Cisplatin-Resistant Human Ovarian Cancer Cells through Downregulation of Phosphoinositide 3-Kinase/Akt Signaling Pathway. Cancer Research 69:23, pages 8910-8917.
Crossref
Dong-Oh Moon, Mun-Ock Kim, Jae-Dong Lee, Yung Hyun Choi & Gi-Young Kim. (2009) Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells. Cancer Letters 286:2, pages 172-179.
Crossref
Mi-Ja Kim, Min Kyu Jeong, Pahn-Shick Chang & JaeHwan Lee. (2009) Radical scavenging activity and apoptotic effects in HT-29 human colon cancer cells of black sesame seed extract. International Journal of Food Science & Technology 44:11, pages 2106-2112.
Crossref
Gyoo Taik Kwon, Han Jin Cho, Won-Yoon Chung, Kwang-Kyun Park, Aree Moon & Jung Han Yoon Park. (2009) Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: possible mediation by decreased JNK/AP-1 signaling. The Journal of Nutritional Biochemistry 20:9, pages 663-676.
Crossref
Xiaoyun Zhang, Jianping Liu, Hua Qiao, Jingman Ni & Yanbin Shi. (2009) Determination and Pharmacokinetics of Isoliquiritigenin in Rat Plasma by RP–LC After Intravenous Administration. Chromatographia 70:3-4, pages 423-430.
Crossref
Ya‐Ling Hsu, Chun‐Chieh Chia, Ping‐Jye Chen, Su‐Er Huang, Soon‐Cen Huang & Po‐Lin Kuo. (2009) Shallot and licorice constituent isoliquiritigenin arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and initiation of the mitochondrial system in human cervical carcinoma HeLa cells. Molecular Nutrition & Food Research 53:7, pages 826-835.
Crossref
Iha Park, Kwang-Kyun Park, Jung Han Yoon Park & Won-Yoon Chung. (2009) Isoliquiritigenin induces G2 and M phase arrest by inducing DNA damage and by inhibiting the metaphase/anaphase transition. Cancer Letters 277:2, pages 174-181.
Crossref
M. K. Pandey, B. Sung, K. S. Ahn & B. B. Aggarwal. (2008) Butein Suppresses Constitutive and Inducible Signal Transducer and Activator of Transcription (STAT) 3 Activation and STAT3-Regulated Gene Products through the Induction of a Protein Tyrosine Phosphatase SHP-1. Molecular Pharmacology 75:3, pages 525-533.
Crossref
Xiao-Ping Ding, Jin Qi, Yan-Xu Chang, Ling-Li Mu, Dan-Ni Zhu & Bo-Yang Yu. (2009) Quality control of flavonoids in Ginkgo biloba leaves by high-performance liquid chromatography with diode array detection and on-line radical scavenging activity detection. Journal of Chromatography A 1216:11, pages 2204-2210.
Crossref
Kayo Henmi, Yoko Hiwatashi, Eri Hikita, Naoya Toyama & Toshihiko Hirano. (2009) Methoxy- and Fluoro-chalcone Derivatives Arrest Cell Cycle Progression and Induce Apoptosis in Human Melanoma Cell A375. Biological & Pharmaceutical Bulletin 32:6, pages 1109-1113.
Crossref
XiuJun Li, Xiaoyan Xue & Paul C. H. Li. (2009) Real-time detection of the early event of cytotoxicity of herbal ingredients on single leukemia cells studied in a microfluidic biochip. Integrative Biology 1:1, pages 90-98.
Crossref
Janmejai K. Srivastava & Sanjay Gupta. 2009. Complementary and Alternative Therapies and the Aging Population. Complementary and Alternative Therapies and the Aging Population 135 158 .
Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto & Richard B. van Breemen. (2008) Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases. Drug Metabolism and Disposition 36:10, pages 2104-2112.
Crossref
Vijayalakshmi Nandakumar, Trygve Tollefsbol, Ada Elgavish & Sabita Saldanha. 2008. Cancer Epigenetics. Cancer Epigenetics 197 214 .
Tatsushi Yoshida, Mano Horinaka, Mami Takara, Mayuko Tsuchihashi, Nobuhiro Mukai, Miki Wakada & Toshiyuki Sakai. (2008) Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells. Environmental Health and Preventive Medicine 13:5, pages 281-287.
Crossref
Dong-chul Kim, Sabarish Ramachandran, Seung-hee Baek, Sang-Hoon Kwon, Kun-Young Kwon, Soon-Do Cha, Insoo Bae & Chi-Heum Cho. (2008) Induction of Growth Inhibition and Apoptosis in Human Uterine Leiomyoma Cells by Isoliquiritigenin. Reproductive Sciences 15:6, pages 552-558.
Crossref
LiRui Zhang, Wei Chen & Xu Li. (2008) A novel anticancer effect of butein: Inhibition of invasion through the ERK1/2 and NF-κB signaling pathways in bladder cancer cells. FEBS Letters 582:13, pages 1821-1828.
Crossref
Marjan Nassiri Asl & Hossein Hosseinzadeh. (2008) Review of Pharmacological Effects of Glycyrrhiza sp. and its Bioactive Compounds . Phytotherapy Research 22:6, pages 709-724.
Crossref
Supaluk Prachayasittikul, Prasit Buraparuangsang, Apilak Worachartcheewan, Chartchalerm Isarankura-Na-Ayudhya, Somsak Ruchirawat & Virapong Prachayasittikul. (2008) Antimicrobial and Antioxidative Activities of Bioactive Constituents from Hydnophytum formicarum Jack.. Molecules 13:4, pages 904-921.
Crossref
Jian Guo, Dongting Liu, Dejan Nikolic, Dongwei Zhu, John M. Pezzuto & Richard B. van Breemen. (2008) In Vitro Metabolism of Isoliquiritigenin by Human Liver Microsomes. Drug Metabolism and Disposition 36:2, pages 461-468.
Crossref
Chang Ki Lee, Seung Hwa Son, Kwang Kyun Park, Jung Han Yoon Park, Soon Sung Lim & Won Yoon Chung. (2008) Isoliquiritigenin Inhibits Tumor Growth and Protects the Kidney and Liver Against Chemotherapy-Induced Toxicity in a Mouse Xenograft Model of Colon Carcinoma. Journal of Pharmacological Sciences 106:3, pages 444-451.
Crossref
Nam Joo Kang, Ki Won Lee, Evgeny A. Rogozin, Yong-Yeon Cho, Yong-Seok Heo, Ann M. Bode, Hyong Joo Lee & Zigang Dong. (2007) Equol, a Metabolite of the Soybean Isoflavone Daidzein, Inhibits Neoplastic Cell Transformation by Targeting the MEK/ERK/p90RSK/Activator Protein-1 Pathway. Journal of Biological Chemistry 282:45, pages 32856-32866.
Crossref
Samuel N. Kikandi, Samira Musah, Kyoungyun Lee, John Hassani, Shawn Rajan, Ailing Zhou & Omowunmi. A. Sadik. (2007) Comparative Studies of Quercetin Interactions with Monophosphate Nucleotides Using UV-Vis Spectroscopy and Electrochemical Techniques. Electroanalysis 19:19-20, pages 2131-2140.
Crossref
Yuan-Li Li, Guo-Ping Gan, Hui-Zhan Zhang, He-Zhen Wu, Chang-Long Li, Yong-Ping Huang, Yan-Wen Liu & Jian-Wen Liu. (2007) A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines. Journal of Ethnopharmacology 113:1, pages 115-124.
Crossref
Manoj K. Pandey, Santosh K. Sandur, Bokyung Sung, Gautam Sethi, Ajaikumar B. Kunnumakkara & Bharat B. Aggarwal. (2007) Butein, a Tetrahydroxychalcone, Inhibits Nuclear Factor (NF)-κB and NF-κB-regulated Gene Expression through Direct Inhibition of IκBα Kinase β on Cysteine 179 Residue. Journal of Biological Chemistry 282:24, pages 17340-17350.
Crossref
Patricia C. Allen. (2007) Anticoccidial Effects of Xanthohumol. Avian Diseases 51:1, pages 21-26.
Crossref
Romina Pedreschi & Luis Cisneros-Zevallos. (2007) Phenolic profiles of Andean purple corn (Zea mays L.). Food Chemistry 100:3, pages 956-963.
Crossref
S. Sale, R. G. Tunstall, K. C. Ruparelia, P. C. Butler, G. A. Potter, W. P. Steward & A. J. Gescher. (2006) Effects of the potential chemopreventive agent DMU-135 on adenoma development in the ApcMin+ mouse. Investigational New Drugs 24:6, pages 459-464.
Crossref
Gudrun Michels, Gamal A. Mohamed, Nadine Weber, Yvonni Chovolou, Andreas Kampkotter, Wim Watjen & Peter Proksch. (2006) Effects of Methylated Derivatives of Luteolin Isolated from Cyperus alopecuroides in Rat H4IIE Hepatoma Cells*. Basic <html_ent glyph="@amp;" ascii="&"/> Clinical Pharmacology <html_ent glyph="@amp;" ascii="&"/> Toxicology 98:2, pages 168-172.
Crossref
Tsutomu Nakayama, Katsuko Kajiya & Shigenori Kumazawa. 2006. 107 133 .
Jae In Jung, Eunkyung Chung, Mi Ra Seon, Hyun-Kyung Shin, Eun Ji Kim, Soon Sung Lim, Won-Yoon Chung, Kwang-Kyun Park & Jung Han Yoon Park. (2006) Isoliquiritigenin (ISL) inhibits ErbB3 signaling in prostate cancer cells. BioFactors 28:3-4, pages 159-168.
Crossref
Michael Samoszuk, Jenny Tan & Guillaume Chorn. (2005) The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts. BMC Complementary and Alternative Medicine 5:1.
Crossref
Rongxia Liu, Jianghao Sun, Kaishun Bi & De-an Guo. (2005) Identification and determination of major flavonoids in rat serum by HPLC–UV and HPLC–MS methods following oral administration of Dalbergia odorifera extract. Journal of Chromatography B 829:1-2, pages 35-44.
Crossref
Masahiro Nishihara, Takashi Nakatsuka & Saburo Yamamura. (2005) Flavonoid components and flower color change in transgenic tobacco plants by suppression of chalcone isomerase gene. FEBS Letters 579:27, pages 6074-6078.
Crossref
Nicole Monfilliette-Cotelle. 2005. Carcinogenic and Anticarcinogenic Food Components. Carcinogenic and Anticarcinogenic Food Components.
Rong-Xia Liu, Qiao Wang, Hong-Zhu Guo, Li Li, Kai-Shun Bi & De-An Guo. (2005) Simultaneous determination of 10 major flavonoids in Dalbergia odorifera by high performance liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis 39:3-4, pages 469-476.
Crossref
Chun-Lin Ye, Feng Qian, Dong-Zhi Wei, Yan-Hua Lu & Jian-Wen Liu. (2005) Induction of apoptosis in K562 human leukemia cells by 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone. Leukemia Research 29:8, pages 887-892.
Crossref
Amr Amin, Aysha Alkaabi, Shamaa Al‐Falasi & Sayel A. Daoud. (2013) Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer . Cell Biology International 29:8, pages 687-694.
Crossref
Ya-Ling Hsu, Po-Lin Kuo & Chun-Ching Lin. (2005) Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells. Life Sciences 77:3, pages 279-292.
Crossref
Yun Wang, Franky L. Chan, Shiuan Chen & Lai K. Leung. (2005) The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase. Life Sciences 77:1, pages 39-51.
Crossref
Jean-Baptiste Daskiewicz, Flore Depeint, Lionel Viornery, Christine Bayet, Geraldine Comte-Sarrazin, Gilles Comte, Jennifer M. Gee, Ian T. Johnson, Karine Ndjoko, Kurt Hostettmann & Denis Barron. (2005) Effects of Flavonoids on Cell Proliferation and Caspase Activation in a Human Colonic Cell Line HT29:  An SAR Study. Journal of Medicinal Chemistry 48:8, pages 2790-2804.
Crossref
Herng-Jiun Lee, Chau-Jong Wang, Hsing-Chun Kuo, Fen-Pi Chou, Lian-Fwu Jean & Tsui-Hwa Tseng. (2005) Induction apoptosis of luteolin in human hepatoma HepG2 cells involving mitochondria translocation of Bax/Bak and activation of JNK. Toxicology and Applied Pharmacology 203:2, pages 124-131.
Crossref
. (2005) Effect of Rhus verniciflua Stokes Extract and Fisetin on UVB-induced Apoptosis in NIH3T3 Cells. Journal of Life Science 15:1, pages 141-146.
Crossref
. (2005) Subacute Inhalation Toxicity Study of Dimethyl Disulfide in F344 Rats. Journal of Life Science 15:1, pages 1-8.
Crossref
Krishan Datt SHARMA & Hitoshi NAGASHIMA. (2005) Protective effects of flavonoids against rubratoxin B toxicity in human hepatocellular carcinoma cells. Mycotoxins 55:2, pages 101-105.
Crossref
Chun-Lin Ye, Jian-Wen Liu, Dong-Zhi Wei, Yan-Hua Lu & Feng Qian. (2004) In vitro anti-tumor activity of 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone against six established human cancer cell lines. Pharmacological Research 50:5, pages 505-510.
Crossref
Martin Albrecht, Wenguo Jiang, James Kumi-DiakaEphraim P. LanskyLyndon M. Gommersall, Amit Patel, Robert E. Mansel, Ishak Neeman, Albert A. Geldof & Moray J. Campbell. (2004) Pomegranate Extracts Potently Suppress Proliferation, Xenograft Growth, and Invasion of Human Prostate Cancer Cells. Journal of Medicinal Food 7:3, pages 274-283.
Crossref
Ya-Ling Hsu, Po-Lin Kuo, Lien-Chai Chiang & Chun-Ching Lin. (2004) ISOLIQUIRITIGENIN INHIBITS THE PROLIFERATION AND INDUCES THE APOPTOSIS OF HUMAN NON-SMALL CELL LUNG CANCER A549 CELLS. Clinical and Experimental Pharmacology and Physiology 31:7, pages 414-418.
Crossref
Omid Sabzevari, Giuseppe Galati, Majid Y Moridani, Arno Siraki & Peter J O’Brien. (2004) Molecular cytotoxic mechanisms of anticancer hydroxychalcones. Chemico-Biological Interactions 148:1-2, pages 57-67.
Crossref
Sanjeev Shukla & Sanjay Gupta. (2004) Suppression of Constitutive and Tumor Necrosis Factor α-Induced Nuclear Factor (NF)-κB Activation and Induction of Apoptosis by Apigenin in Human Prostate Carcinoma PC-3 Cells: Correlation with Down-Regulation of NF-κB-Responsive Genes. Clinical Cancer Research 10:9, pages 3169-3178.
Crossref
Tetsuyuki Takahashi, Nobuo Takasuka, Masaaki Iigo, Masaki Baba, Hoyoku Nishino, Hiroyuki Tsuda & Toru Okuyama. (2005) Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E 2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development . Cancer Science 95:5, pages 448-453.
Crossref
Tsunehiro Ii, Yoshiko Satomi, Daishiro Katoh, Junichi Shimada, Masaki Baba, Toru Okuyama, Hoyoku Nishino & Nobuo Kitamura. (2004) Induction of cell cycle arrest and p21CIP1/WAF1 expression in human lung cancer cells by isoliquiritigenin. Cancer Letters 207:1, pages 27-35.
Crossref
Sanjeev Shukla & Sanjay Gupta. (2004) Molecular mechanisms for apigenin‐induced cell‐cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cells. Molecular Carcinogenesis 39:2, pages 114-126.
Crossref
Dae Gill Kang, An Sook Lee, Yeun Ja Mun, Won Hong Woo, Youn Chul Kim, Eun Jin Sohn, Mi Kyong Moon & Ho Sub Lee. (2004) Butein Ameliorates Renal Concentrating Ability in Cisplatin-Induced Acute Renal Failure in Rats. Biological & Pharmaceutical Bulletin 27:3, pages 366-370.
Crossref
Alexander Gosslau & Kuang Yu Chen. (2004) Nutraceuticals, apoptosis, and disease prevention. Nutrition 20:1, pages 95-102.
Crossref
Mohamed M Rafi. (2004) Elucidating the role of nutraceuticals in overexpressing antiapoptotic proteins in prostate cancer. Nutrition 20:1, pages 78-82.
Crossref
Hye Won Lee, Hye Young Ji, Hong Il Lee, Hae-Kyoung Kim, Dong Hwan Sohn, Youn-Chul Kim, Hun Taeg Chung & Hye Suk Lee. (2004) Determination of butein in rat serum by high performance liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis 34:1, pages 227-231.
Crossref
Gary D. Stoner & Bruce C. Casto. 2004. Cancer Chemoprevention. Cancer Chemoprevention 419 435 .
Gianna Roscetti, Ornella Franzese, Alessandro Comandini & Enzo Bonmassar. (2004) Cytotoxic activity of Hypericum perforatum L. on K562 erythroleukemic cells: differential effects between methanolic extract and hypericin . Phytotherapy Research 18:1, pages 66-72.
Crossref
Yen-Chou Chen, Shing-Chuan Shen & Hui-Yi Lin. (2003) Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids. Biochemical Pharmacology 66:7, pages 1139-1150.
Crossref
Reiko Kamei, Michinori Kadokura, Yoshinori Kitagawa, Osamu Hazeki & Shinzo Oikawa. (2003) 2′-benzyloxychalcone derivatives stimulate glucose uptake in 3T3-L1 adipocytes. Life Sciences 73:16, pages 2091-2099.
Crossref
Richard Garry Beniston & Maria Saveria Campo. (2003) Quercetin elevates p27Kip1 and arrests both primary and HPV16 E6/E7 transformed human keratinocytes in G1. Oncogene 22:35, pages 5504-5514.
Crossref
Wenying Ren, Zhenhua Qiao, Hongwei Wang, Lei Zhu & Li Zhang. (2003) Flavonoids: Promising anticancer agents. Medicinal Research Reviews 23:4, pages 519-534.
Crossref
D.P. Shrayer, H. Lukoff, T. King & P. Calabresi. (2003) The effect of Taurolidine on adherent and floating subpopulations of melanoma cells. Anti-Cancer Drugs 14:4, pages 295-303.
Crossref
C Martínez, J Yàñez, V Vicente, M Alcaraz, O Benavente-García, J Castillo, J Lorente & J A Lozano. (2003) Effects of several polyhydroxylated flavonoids on the growth of B16F10 melanoma and Melan-a melanocyte cell lines. Melanoma Research 13:1, pages 3-9.
Crossref
Ming Shi. (2003) Synergetic anticancer effect of combined quercetin and recombinant adenoviral vector expressing human wild-type p53, GM-CSF and B7-1 genes on hepatocellular carcinoma cells in vitro . World Journal of Gastroenterology 9:1, pages 73.
Crossref
Ayumi Denda, Wakashi Kitayama, Rawiwan Puatanachokchai, Masahiro Tsutsumi, Yoichi Konishi, Hiroki Kuniyasu, Masaki Baba, Toru Okuyama & Hoyoku Nishino. (2003) Effects of Isoliquirithigenin on the Development of Preneoplastic Liver Lesions Caused by a Choline-Deficient, L-Amino Acid-Defined Diet and on the Urinary Bladder Carcinogenesis by N-Butyl-N-(4-hydroxybutyl)nitrosamine in Rats. Journal of Toxicologic Pathology 16:4, pages 201-207.
Crossref
Dae Gill Kang, Yun Cheol Kim, Eun Jin Sohn, Yun Mi Lee, An Sook Lee, Ming Hao Yin & Ho Sub Lee. (2003) Hypotensive Effect of Butein via the Inhibition of Angiotensin Converting Enzyme. Biological & Pharmaceutical Bulletin 26:9, pages 1345-1347.
Crossref
Naomi Katsube, Keiko Iwashita, Tojiro Tsushida, Koji Yamaki & Masuko Kobori. (2002) Induction of Apoptosis in Cancer Cells by Bilberry ( Vaccinium myrtillus ) and the Anthocyanins . Journal of Agricultural and Food Chemistry 51:1, pages 68-75.
Crossref
Guray Saydam, H.Hakan Aydin, Fahri Sahin, Ozlem Kucukoglu, Ercin Erciyas, Ender Terzioglu, Filiz Buyukkececi & Serdar Bedii Omay. (2003) Cytotoxic and inhibitory effects of 4,4′-dihydroxy chalcone (RVC-588) on proliferation of human leukemic HL-60 cells. Leukemia Research 27:1, pages 57-64.
Crossref
Ryuichi Kato, Katsuko Kajiya, Hiromi Tokumoto, Shigenori Kumazawa & Tsutomu Nakayama. (2003) Affinity of isoflavonoids for lipid bilayers evaluated with liposomal systems. BioFactors 19:3-4, pages 179-187.
Crossref
Shinjiro Yamamoto, Koji Nakano, Chihiro Ishikawa, Megumi Yamamoto, Yoko Matsumoto, Masayoshi Iwahara, Shintaro Furusaki & Ryuichi Ueoka. (2002) Enhanced inhibitory effects of extracts from Ginkgo biloba L. leaves encapsulated in hybrid liposomes on the growth of tumor cells in vitro. Biochemical Engineering Journal 12:2, pages 125-130.
Crossref
Marcello Maggiolini, Giancarlo Statti, Adele Vivacqua, Sabrina Gabriele, Vittoria Rago, Monica Loizzo, Francesco Menichini & Sebastiano Amdò. (2002) Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology 82:4-5, pages 315-322.
Crossref
Burcu Meric, Kagan Kerman, Dilsat Ozkan, Pinar Kara, Arzum Erdem, Ozlem Kucukoglu, Ercin Erciyas & Mehmet Ozsoz. (2002) Electrochemical biosensor for the interaction of DNA with the alkylating agent 4,4′-dihydroxy chalcone based on guanine and adenine signals. Journal of Pharmaceutical and Biomedical Analysis 30:4, pages 1339-1346.
Crossref
Shoji Yamazaki, Tatuo Morita, Hitoshi Endo, Toshiro Hamamoto, Masaki Baba, Yoshiko Joichi, Sanae Kaneko, Yoshihito Okada, Toru Okuyama, Hoyoku Nishino & Akihiko Tokue. (2002) Isoliquiritigenin suppresses pulmonary metastasis of mouse renal cell carcinoma. Cancer Letters 183:1, pages 23-30.
Crossref
Jung-Hye Choi, Bo-Rim Seo, Seong-Hoon Seo, Kyung-Tae Lee, Jae-Hoon Park, Hee-Juhn Park, Jong-Won Choi, Yoshie Itoh & Ken-ichi Miyamoto. (2002) Costunolide induces differentiation of human leukemia HL-60 cells. Archives of Pharmacal Research 25:4, pages 480-484.
Crossref
Lilia I. Melnik, Bridgette M. Collins-Burow, Daniel K. Pace, John A. McLachlan, Matthew E. Burow, Daniel E. Frigo, Bich N. Duong & Lawanda S. Schief. (2002) Flavonoid Phytochemicals Regulate Activator Protein-1 Signal Transduction Pathways in Endometrial and Kidney Stable Cell Lines. The Journal of Nutrition 132:7, pages 1848-1853.
Crossref
M. Piantelli, D. Tatone, G. Castrilli, F. Savini, N. Maggiano, L. M. Larocca, F. O. Ranelletti & P. G. Natali. (2001) Quercetin and tamoxifen sensitize human melanoma cells to hyperthermia. Melanoma Research 11:5, pages 469-476.
Crossref
Sanjay Gupta, Farrukh Afaq & Hasan Mukhtar. (2001) Selective Growth-Inhibitory, Cell-Cycle Deregulatory and Apoptotic Response of Apigenin in Normal versus Human Prostate Carcinoma Cells. Biochemical and Biophysical Research Communications 287:4, pages 914-920.
Crossref

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