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Bioscience, Biotechnology, and Biochemistry Volume 65, 2001 - Issue 9
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Original Articles

Enzyme-assisted Preparation of D-tert.-Leucine

Kurt LAUMENNovartis Pharma AG, Core Technology Area
,
Oreste GHISALBANovartis Pharma AG, Core Technology Area
&
Kurt AUERNovartis Pharma AG, Core Technology Area
Pages 1977-1980 | Received 09 Jan 2001, Accepted 25 Apr 2001, Published online: 22 May 2014

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Shu‐Lai Liu, Qing‐Xun Song, Dong‐Zhi Wei, Ye‐Wang Zhang & Xue‐Dong Wang. (2006) Preparation of Optically Pure tert‐Leucine by Penicillin G Acylase‐Catalyzed Resolution. Preparative Biochemistry & Biotechnology 36:3, pages 235-241.
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Articles from other publishers (17)

Weiming Liu, Jixing Luo, Xiaojian Zhuang, Wenhe Shen, Yang Zhang, Shuang Li, Yi Hu & He Huang. (2014) Efficient preparation of enantiopure l-tert-leucine through immobilized penicillin G acylase catalyzed kinetic resolution in aqueous medium. Biochemical Engineering Journal 83, pages 116-120.
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Margarita Escudero‐Casao & Eusebio Juaristi. (2012) Asymmetric Synthesis of β 2 ‐homo‐ tert ‐Leucine via Radical Addition to Enantiopure N ‐Fumaroylhexahydrobenzooxazolidin‐2‐one . Helvetica Chimica Acta 95:10, pages 1714-1722.
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Jian-Zhong Jin, Dong-Liang Chang & Jie Zhang. (2010) Discovery and Application of New Bacterial Strains for Asymmetric Synthesis of L-Tert-Butyl Leucine in High Enantioselectivity. Applied Biochemistry and Biotechnology 164:3, pages 376-385.
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Rainer Machauer, Kurt Laumen, Siem Veenstra, Jean-Michel Rondeau, Marina Tintelnot-Blomley, Claudia Betschart, Anne-Lise Jaton, Sandrine Desrayaud, Matthias Staufenbiel, Sabine Rabe, Paolo Paganetti & Ulf Neumann. (2009) Macrocyclic peptidomimetic ?-secretase (BACE-1) inhibitors with activity in vivo. Bioorganic & Medicinal Chemistry Letters 19:5, pages 1366-1370.
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Philippe Bisel, Loay Al-Momani & Michael Müller. (2008) The tert-butyl group in chemistry and biology. Organic & Biomolecular Chemistry 6:15, pages 2655.
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Cara E. Humphrey, Markus Furegati, Kurt Laumen, Luigi La Vecchia, Thomas Leutert, J. Constanze D. Müller-Hartwieg & Markus Vögtle. (2007) Optimized Synthesis of l - m -Tyrosine Suitable for Chemical Scale-Up . Organic Process Research & Development 11:6, pages 1069-1075.
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Roger A. Sheldon. (2007) Enzyme Immobilization: The Quest for Optimum Performance. Advanced Synthesis & Catalysis 349:8-9, pages 1289-1307.
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Irene Fotakopoulou, Efrosini Barbayianni, Violetta Constantinou-Kokotou, Uwe T. Bornscheuer & George Kokotos. (2007) Enzymatic Removal of Carboxyl Protecting Groups. III. Fast Removal of Allyl and Chloroethyl Esters by Bacillus subtilis Esterase (BS2) . The Journal of Organic Chemistry 72:3, pages 782-786.
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Eleonora Agosta, Antonio Caligiuri, Paola D’Arrigo, Stefano Servi, Davide Tessaro & Renato Canevotti. (2006) Enzymatic approach to both enantiomers of N-Boc hydrophobic amino acids. Tetrahedron: Asymmetry 17:13, pages 1995-1999.
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K. Laumen & O. Ghisalba. (2006) Easy Access to Enantiomerically Pure Nonproteinogenic Amino Acids. Engineering in Life Sciences 6:2, pages 193-194.
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Oh-Jin Park, Sang-Hyun Lee, Tae-Yoon Park, Sang-Who Lee & Koon-Ho Cho. (2005) Enzyme-catalyzed preparation of methyl (R)-N-(2,6-dimethylphenyl)alaninate: a key intermediate for (R)-metalaxyl. Tetrahedron: Asymmetry 16:6, pages 1221-1225.
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Masayuki Kurokawa & Takeshi Sugai. (2004) Both Enantiomers of N -Boc-indoline-2-carboxylic Esters . Bulletin of the Chemical Society of Japan 77:5, pages 1021-1025.
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Werner Hummel, Mutlu Kuzu & Birgit Geueke. (2003) An Efficient and Selective Enzymatic Oxidation System for the Synthesis of Enantiomerically Pure d - tert -Leucine . Organic Letters 5:20, pages 3649-3650.
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Masayuki Kurokawa, Takeyuki Shindo, Masumi Suzuki, Nobuyoshi Nakajima, Kohji Ishihara & Takeshi Sugai. (2003) Enzyme-catalyzed enantiomeric resolution of N-Boc-proline as the key-step in an expeditious route towards RAMP. Tetrahedron: Asymmetry 14:10, pages 1323-1333.
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Frank Bordusa. (2002) Proteases in Organic Synthesis. Chemical Reviews 102:12, pages 4817-4868.
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Kurt Laumen, Matthias Kittelmann & Oreste Ghisalba. (2002) Chemo-enzymatic approaches for the creation of novel chiral building blocks and reagents for pharmaceutical applications. Journal of Molecular Catalysis B: Enzymatic 19-20, pages 55-66.
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Eric Francotte, Thomas Leutert, Luiggi La Vecchia, Flavio Ossola, Paul Richert & Alfred Schmidt. (2002) Preparative resolution of the enantiomers ofTert-leucine derivatives by simulated moving bed chromatography. Chirality 14:4, pages 313-317.
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