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Original Articles

Hibiscus Acid as an Inhibitor of Starch Digestion in the Caco-2 Cell Model System

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Pages 2087-2089 | Received 17 Jan 2001, Accepted 22 May 2001, Published online: 22 May 2014

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Manisha Singh, Thilini Thrimawithana, Ravi Shukla & Benu Adhikari. (2022) Inhibition of enzymes associated with obesity by the polyphenol-rich extracts of Hibiscus sabdariffa. Food Bioscience 50, pages 101992.
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Ixchell Y. Sedillo-Torres, Álvaro O. Hernández-Rangel, Yolanda Gómez-y-Gómez, Daniel Cortés-Avalos, Blanca Estela García-Pérez, Juan C. Villalobos-Rocha, César H. Hernández-Rodríguez, Luis Gerardo Zepeda-Vallejo, Paulina Estrada-de los Santos, María Elena Vargas-Díaz & Jose Antonio Ibarra. (2022) Hibiscus Acid from Hibiscus sabdariffa L. Inhibits Flagellar Motility and Cell Invasion in Salmonella enterica. Molecules 27:3, pages 655.
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Harry G. Preuss & Debasis Bagchi. 2022. Nutrition and Functional Foods in Boosting Digestion, Metabolism and Immune Health. Nutrition and Functional Foods in Boosting Digestion, Metabolism and Immune Health 289 307 .
Sainath S. Kasar, Vijay L. Maheshwari & Pankaj K. Pawar. 2022. Natural Products as Enzyme Inhibitors. Natural Products as Enzyme Inhibitors 59 104 .
Andrea Devecchi, Sonia Demasi, Francesca Saba, Rosalba Rosato, Roberto Gambino, Valentina Ponzo, Antonella De Francesco, Paola Massarenti, Simona Bo & Valentina Scariot. (2021) Compositional Characteristics and Antioxidant Activity of Edible Rose Flowers and Their Effect on Phenolic Urinary Excretion. Polish Journal of Food and Nutrition Sciences, pages 383-392.
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Chao Tang, Liangyu Kong, Mengyuan Shan, Zhaoxin Lu & Yingjian Lu. (2021) Protective and ameliorating effects of probiotics against diet-induced obesity: A review. Food Research International 147, pages 110490.
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Tong Li, Jianjun Yang, Hongxing Zhang, Yuanhong Xie & Junhua Jin. (2020) Bifidobacterium from breastfed infant faeces prevent high‐fat‐diet‐induced glucose tolerance impairment, mediated by the modulation of glucose intake and the incretin hormone secretion axis . Journal of the Science of Food and Agriculture 100:8, pages 3308-3318.
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Jeannett Izquierdo-Vega, Diego Arteaga-Badillo, Manuel Sánchez-Gutiérrez, José Morales-González, Nancy Vargas-Mendoza, Carlos Gómez-Aldapa, Javier Castro-Rosas, Luis Delgado-Olivares, Eduardo Madrigal-Bujaidar & Eduardo Madrigal-Santillán. (2020) Organic Acids from Roselle (Hibiscus sabdariffa L.)—A Brief Review of Its Pharmacological Effects. Biomedicines 8:5, pages 100.
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Fenfen Yan, Na Li, Yingxue Yue, Chengfeng Wang, Li Zhao, Smith Etareri Evivie, Bailiang Li & Guicheng Huo. (2020) Screening for Potential Novel Probiotics With Dipeptidyl Peptidase IV-Inhibiting Activity for Type 2 Diabetes Attenuation in vitro and in vivo. Frontiers in Microbiology 10.
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Sandra Pimentel-Moral, Isabel Borrás-Linares, Jesús Lozano-Sánchez, David Arráez-Román, Antonio Martínez-Férez & Antonio Segura-Carretero. (2019) Supercritical CO2 extraction of bioactive compounds from Hibiscus sabdariffa. The Journal of Supercritical Fluids 147, pages 213-221.
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Young-Sil Lee, Won-Kyung Yang, Hwa Kim, Bokkee Min, Nuria Caturla, Jonathan Jones, Yang-Chun Park, Young-Cheol Lee & Seung-Hyung Kim. (2018) Metabolaid® Combination of Lemon Verbena and Hibiscus Flower Extract Prevents High-Fat Diet-Induced Obesity through AMP-Activated Protein Kinase Activation. Nutrients 10:9, pages 1204.
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Ahmed M. Zheoat, Alexander I. Gray, John O. Igoli, Alan R. Kennedy & Valerie A. Ferro. (2017) Crystal structures of hibiscus acid and hibiscus acid dimethyl ester isolated from Hibiscus sabdariffa (Malvaceae) . Acta Crystallographica Section E Crystallographic Communications 73:9, pages 1368-1371.
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María Herranz-López, Mariló Olivares-Vicente, José Encinar, Enrique Barrajón-Catalán, Antonio Segura-Carretero, Jorge Joven & Vicente Micol. (2017) Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity. Nutrients 9:8, pages 907.
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Abdul-Lateef Molan & Abdulkhaliq Saleh Mahdy. (2016) Total Phenolics, Antioxidant Activity and Anti-Diabetic Capacities of Selected Iraqi Medicinal Plants. American Journal of Life Science Researches 4:2, pages 47-59.
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Noriaki Kasuya, Megumi Okuyama, Kazutaka Yoshida, Satoshi Sunabori, Hiroyuki Suganuma, Isamu Murata, Yutaka Inoue & Ikuo Kanamoto. (2016) Prior or Concomitant Drinking of Vegetable Juice with a Meal Attenuates Postprandial Blood Glucose Elevation in Healthy Young Adults. Food and Nutrition Sciences 07:09, pages 797-806.
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Zhu Zeng, Junyi Luo, Fanglei Zuo, Ying Zhang, Huiqin Ma & Shangwu Chen. (2016) Screening for potential novel probiotic Lactobacillus strains based on high dipeptidyl peptidase IV and α-glucosidase inhibitory activity. Journal of Functional Foods 20, pages 486-495.
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Hongxia Chen, Jiangjiang Zhang, Heng Wu, Kwangnak Koh & Yongmei Yin. (2015) Sensitive colorimetric assays for ?-glucosidase activity and inhibitor screening based on unmodified gold nanoparticles. Analytica Chimica Acta 875, pages 92-98.
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Harry Preuss & Dallas Clouatre. 2015. Nutritional and Integrative Strategies in Cardiovascular Medicine. Nutritional and Integrative Strategies in Cardiovascular Medicine 147 178 .
E. Mutai, R. Sunkara, Jorge Vizcarra, L. T. Walker & M. Verghese. (2015) Antioxidant, Enzyme Inhibitory and Anti-Obesity Potential of Sorrel Calyx Extracts in 3T3-L1 Adipocytes. Food and Nutrition Sciences 06:05, pages 452-465.
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Inês Da-Costa-Rocha, Bernd Bonnlaender, Hartwig Sievers, Ivo Pischel & Michael Heinrich. (2014) Hibiscus sabdariffa L. – A phytochemical and pharmacological review. Food Chemistry 165, pages 424-443.
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Pei Chen, Qiuxiang Zhang, Hui Dang, Xiaoming Liu, Fengwei Tian, Jianxin Zhao, Yongquan Chen, Hao Zhang & Wei Chen. (2014) Screening for potential new probiotic based on probiotic properties and α-glucosidase inhibitory activity. Food Control 35:1, pages 65-72.
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T. K. LimT. K. Lim. 2014. Edible Medicinal and Non Medicinal Plants. Edible Medicinal and Non Medicinal Plants 324 370 .
Sirichai Adisakwattana, Thanyachanok Ruengsamran, Patcharaporn Kampa & Weerachat Sompong. (2012) In vitro inhibitory effects of plant-based foods and their combinations on intestinal α-glucosidase and pancreatic α-amylase. BMC Complementary and Alternative Medicine 12:1.
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Takashi Yamada. 2010. Biotechnology in Functional Foods and Nutraceuticals. Biotechnology in Functional Foods and Nutraceuticals 265 276 .
Hassan Mozaffari-KhosraviBeman-Ali Jalali-KhanabadiMohammad Afkhami-ArdekaniFarhad Fatehi. (2009) Effects of Sour Tea ( Hibiscus sabdariffa ) on Lipid Profile and Lipoproteins in Patients with Type II Diabetes . The Journal of Alternative and Complementary Medicine 15:8, pages 899-903.
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O. Carvajal-Zarrabal, P. M. Hayward-Jones, Z. Orta-Flores, C. Nolasco-Hipólito, D. M. Barradas-Dermitz, M. G. Aguilar-Uscanga & M. F. Pedroza-Hernández. (2009) Effect of Hibiscus sabdariffa L. Dried Calyx Ethanol Extract on Fat Absorption-Excretion, and Body Weight Implication in Rats . Journal of Biomedicine and Biotechnology 2009, pages 1-5.
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Jin-Kyung Kim, Hongseob So, Myung-Ja Youn, Hyung-Jin Kim, Yunha Kim, Channy Park, Se-Jin Kim, Young-Ae Ha, Kyu-Yun Chai, Shin-Moo Kim, Ki-Young Kim & Raekil Park. (2007) Hibiscus sabdariffa L. water extract inhibits the adipocyte differentiation through the PI3-K and MAPK pathway. Journal of Ethnopharmacology 114:2, pages 260-267.
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Junkyu Han, Susumu Inoue & Hiroko Isoda. (2007) Effects of silkworm powder on glucose absorption by human intestinal epithelial cell line Caco-2. Journal of Natural Medicines 61:4, pages 387-390.
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Takashi Yamada, Hiroyuki Hida & Yasuhiro Yamada. (2007) Chemistry, physiological properties, and microbial production of hydroxycitric acid. Applied Microbiology and Biotechnology 75:5, pages 977-982.
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Takashi Yamada, Hiroyuki Hida & Yasuhiro Yamada. (2007) Isolation of hydroxycitric acid-producing Streptomyces sp. U121 and generation of improved mutants by genome shuffling. Actinomycetologica 21:1, pages 40-45.
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Chanida Hansawasdi & Jun Kawabata. (2006) ?-Glucosidase inhibitory effect of mulberry (Morus alba) leaves on Caco-2. Fitoterapia 77:7-8, pages 568-573.
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