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Bioscience, Biotechnology, and Biochemistry Volume 66, 2002 - Issue 4
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Original Articles

5-Halogenated Thymidine Analogues Induce a Senescence-like Phenomenon in HeLa Cells

Eriko MICHISHITADivision of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City UniversityMaioka-cho 641-12, Totsuka-ku, Yokohama 244-0813, Japan
,
Naoto MATSUMURADivision of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City UniversityMaioka-cho 641-12, Totsuka-ku, Yokohama 244-0813, Japan
,
Toshihiro KURAHASHIDivision of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City UniversityMaioka-cho 641-12, Totsuka-ku, Yokohama 244-0813, Japan
,
Toshikazu SUZUKIDivision of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City UniversityMaioka-cho 641-12, Totsuka-ku, Yokohama 244-0813, Japan
,
Hideki OGINODivision of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City UniversityMaioka-cho 641-12, Totsuka-ku, Yokohama 244-0813, Japan
,
Michihiko FUJIIDivision of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City UniversityMaioka-cho 641-12, Totsuka-ku, Yokohama 244-0813, Japan
&
Dai AYUSAWADivision of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City UniversityMaioka-cho 641-12, Totsuka-ku, Yokohama 244-0813, Japan
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Pages 877-879 | Received 12 Sep 2001, Accepted 13 Dec 2001, Published online: 22 May 2014

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Morio ENDOH, Kensuke MIKI, Mohammad Nazir HOSSAIN, Michihiko FUJII & Dai AYUSAWA. (2007) 5-Bromodeoxyuridine Increases Transient Expression of Ectopic Genes in Human Cells. Bioscience, Biotechnology, and Biochemistry 71:4, pages 1098-1102.
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Articles from other publishers (12)

Jessica L. Macer-Wright, Naomi R. Stanley, Neil Portman, Joanne T. Tan, Christina Bursill, Benjamin S. Rayner & Clare L. Hawkins. (2019) A Role for Chlorinated Nucleosides in the Perturbation of Macrophage Function and Promotion of Inflammation. Chemical Research in Toxicology 32:6, pages 1223-1234.
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Hiroaki AdachiYuhko MurakamiNaokazu HottaHiroshi TanakaSatoru Nakata. (2015) Investigation of the Skin Aging Mechanism Focusing on Stratifin. Journal of Society of Cosmetic Chemists of Japan 49:3, pages 211-217.
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Ikue Kikuchi, Yuji Nakayama, Takao Morinaga, Yasunori Fukumoto & Naoto Yamaguchi. (2014) A decrease in cyclin B1 levels leads to polyploidization in DNA damage‐induced senescence. Cell Biology International 34:6, pages 645-653.
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Mohammad Nazir Hossain, Michihiko Fuji, Kensuke Miki, Morio Endoh & Dai Ayusawa. (2006) Downregulation of hnRNP C1/C2 by siRNA sensitizes HeLa cells to various stresses. Molecular and Cellular Biochemistry 296:1-2, pages 151-157.
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Junko Takeshita, Jaeman Byun, Thomas Q. Nhan, David K. Pritchard, Subramaniam Pennathur, Steven M. Schwartz, Alan Chait & Jay W. Heinecke. (2006) Myeloperoxidase Generates 5-Chlorouracil in Human Atherosclerotic Tissue. Journal of Biological Chemistry 281:6, pages 3096-3104.
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M. Ferenac, D. Polancec, M. Huzak, O. M. Pereira-Smith & I. Rubelj. (2005) Early-Senescing Human Skin Fibroblasts Do Not Demonstrate Accelerated Telomere Shortening. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 60:7, pages 820-829.
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Sachi Minagawa, Kazuhiko Nakabayashi, Michihiko Fujii, Stephen W. Scherer & Dai Ayusawa. (2005) Early BrdU-responsive genes constitute a novel class of senescence-associated genes in human cells. Experimental Cell Research 304:2, pages 552-558.
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Sachi Minagawa, Kazuhiko Nakabayashi, Michihiko Fujii, Stephen W Scherer & Dai Ayusawa. (2004) Functional and chromosomal clustering of genes responsive to 5-bromodeoxyuridine in human cells. Experimental Gerontology 39:7, pages 1069-1078.
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Dai Ayusawa. 2003. Aging of Cells in and Outside the Body. Aging of Cells in and Outside the Body 239 255 .
. (2002) Anti-Aging Medicine LiteratureWatch. Journal of Anti-Aging Medicine 5:3, pages 291-311.
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Eriko Michishita, Toshihiro Kurahashi, Toshikazu Suzuki, Masafumi Fukuda, Michihiko Fujii, Hisashi Hirano & Dai Ayusawa. (2002) Changes in nuclear matrix proteins during the senescence-like phenomenon induced by 5-chlorodeoxyuridine in HeLa cells. Experimental Gerontology 37:7, pages 885-890.
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Toshikazu Suzuki, Eriko Michishita, Hideki Ogino, Michihiko Fujii & Dai Ayusawa. (2002) Synergistic Induction of the Senescence-Associated Genes by 5-Bromodeoxyuridine and AT-Binding Ligands in HeLa Cells. Experimental Cell Research 276:2, pages 174-184.
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