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Original Articles

Hypoglycemic Activity of Eriobotrya japonica Seeds in Type 2 Diabetic Rats and Mice

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Pages 686-693 | Received 28 Jun 2007, Accepted 30 Nov 2007, Published online: 22 May 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Atul Dhiman, Rajat Suhag, Dhruv Thakur, Viresh Gupta & Pramod K Prabhakar. (2022) Current Status of Loquat (Eriobotrya Japonica Lindl.): Bioactive Functions, Preservation Approaches, and Processed Products. Food Reviews International 38:sup1, pages 286-316.
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Seung-Shick Shin, Byungdoo Hwang, Soo-Bok Lee, Wun-Jae Kim & Sung-Kwon Moon. (2017) Ethanol extract of loquat fruit skin inhibits the proliferation and metastatic potential of EJ human bladder carcinoma cells. Animal Cells and Systems 21:5, pages 323-331.
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Articles from other publishers (28)

Saverio Nucera, Rosa Maria Bulotta, Stefano Ruga, Rosamaria Caminiti, Maria Serra, Roberto Bava, Fabio Castagna, Carmine Lupia, Mariangela Marrelli, Filomena Conforti, Giancarlo Statti, Vincenzo Mollace & Ernesto Palma. (2023) Natural Products for the Treatment of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review. Scientia Pharmaceutica 91:4, pages 53.
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Ridhi Bajaj, Manisha Shekhawat, Anu Rani, Gajendra Singh & Virender Kumar. (2023) Alternative Approach of Nutraceuticals in Management of Diabetes Mellitus. Current Nutrition & Food Science 19:7, pages 692-702.
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Zainab R. Abdelrahman, Yasser K. Bustanji & Shtaywy S. Abdalla. (2022) Ethanol Extracts of Eriobotrya japonica (Loquat) Seeds, Leaves, and Fruits Have Anti-obesity and Hypolipidemic Effects in Rats . Pharmacognosy Magazine 19:1, pages 56-65.
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Prawej Ansari, Samia Akther, J. M. A. Hannan, Veronique Seidel, Nusrat Jahan Nujat & Yasser H. A. Abdel-Wahab. (2022) Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus. Molecules 27:13, pages 4278.
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Ruoyun Wu, Lina Zhou, Yan Chen, Xiaoqin Ding, Yan Liu, Bei Tong, Han Lv, Xiuhua Meng, Jing Li, Tunyu Jian & Jian Chen. (2022) Sesquiterpene glycoside isolated from loquat leaf targets gut microbiota to prevent type 2 diabetes mellitus in db/db mice. Food & Function 13:3, pages 1519-1534.
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Biswanath Dinda & Manikarna Dinda. 2022. Natural Products in Obesity and Diabetes. Natural Products in Obesity and Diabetes 101 275 .
Han Lü, Ru-Po Lee, Jianjun Huang, Jian Chen, Vay-Liang W. Go, Zhaoping Li & Qing-Yi Lu. (2020) A new HPLC–UV method for the quantification of terpenoids and antioxidant activity of commercial loquat leaf tea and preparation. Journal of Food Measurement and Characterization 14:2, pages 1085-1091.
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Prerna Gupta, Kundu Priyanka & Chikkala Sivanand. 2020. Antioxidants in Fruits: Properties and Health Benefits. Antioxidants in Fruits: Properties and Health Benefits 577 592 .
N. A. Sagar, S. Pareek, R. Bhardwaj & N. Vyas. 2020. Bioactive Compounds in Underutilized Fruits and Nuts. Bioactive Compounds in Underutilized Fruits and Nuts 123 143 .
N. A. Sagar, S. Pareek, R. Bhardwaj & N. Vyas. 2019. Bioactive Compounds in Underutilized Fruits and Nuts. Bioactive Compounds in Underutilized Fruits and Nuts 1 21 .
Yuan Fu, Qin Yuan, Shang Lin, Wen Liu, Gang Du, Li Zhao, Qing Zhang, De-Rong Lin, Yun-Tao Liu, Wen Qin, De-Qiang Li & Ding-Tao Wu. (2019) Physicochemical characteristics and biological activities of polysaccharides from the leaves of different loquat (Eriobotrya japonica) cultivars. International Journal of Biological Macromolecules 135, pages 274-281.
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Maxwell Osaronowen Egua. 2019. Pharmacognosy - Medicinal Plants. Pharmacognosy - Medicinal Plants.
Nak-Won Seong, Heung-Sik Seo, Jun-Ho Kim, Yong-Jae Kim, Eun Kim, Joon-Yeol Lee, Je-Won Ko & Jong-Choon Kim. (2018) A 13-week subchronic toxicity study of an Eriobotrya japonica leaf extract in rats. Journal of Ethnopharmacology 226, pages 1-10.
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Aisha Saleem KhanAisha Saleem Khan. 2017. Medicinally Important Trees. Medicinally Important Trees 21 53 .
Yilong Liu, Wenna Zhang, Changjie Xu & Xian Li. (2016) Biological Activities of Extracts from Loquat (Eriobotrya japonica Lindl.): A Review. International Journal of Molecular Sciences 17:12, pages 1983.
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Jingxiao Zhang, Yan Li, Su-Shing Chen, Lilei Zhang, Jinghui Wang, Yinfeng Yang, Shuwei Zhang, Yanqiu Pan, Yonghua Wang & Ling Yang. (2015) Systems Pharmacology Dissection of the Anti-Inflammatory Mechanism for the Medicinal Herb Folium Eriobotryae. International Journal of Molecular Sciences 16:2, pages 2913-2941.
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Ravirajsinh Jadeja, Ranjitsinh V. Devkar & Srinivas Nammi. (2014) Herbal Medicines for the Treatment of Nonalcoholic Steatohepatitis: Current Scenario and Future Prospects. Evidence-Based Complementary and Alternative Medicine 2014, pages 1-18.
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Hee-Sook Cho & Kyung-Hee Kim. (2013) Quality Characteristics of Cookies Prepared with Loquat (Eriobotrya japonica Lindl.) Leaf Powder. Journal of the Korean Society of Food Science and Nutrition 42:11, pages 1799-1804.
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In-Duck Park. (2012) Quality Characteristics of Tofu Added with Loquat (Eriobotrya japonica Lindl.) Leaf Powder. Journal of the Korean Society of Food Culture 27:5, pages 521-527.
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Daisy Pitchai & Rajalakshmi Manikkam. (2011) Hypoglycemic and insulin mimetic impact of catechin isolated from Cassia fistula: a substantiate in silico approach through docking analysis. Medicinal Chemistry Research 21:9, pages 2238-2250.
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T. K. LimT. K. Lim. 2012. Edible Medicinal And Non-Medicinal Plants. Edible Medicinal And Non-Medicinal Plants 381 394 .
Ju-Sang Kim, Ramasamy Harikrishnan, Man-Chul Kim, Ik-Soo Jang, Dong-Hwi Kim, Seung-Hyun Hong, Chellam Balasundaram & Moon-Soo Heo. (2011) Enhancement of Eriobotrya japonica extracts on non-specific immune response and disease resistance in kelp grouper Epinephelus bruneus against Vibrio carchariae. Fish & Shellfish Immunology 31:6, pages 1193-1200.
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Mi-Jeong Kim, Jeongmin Lee, Ah-Reum Seong, Yoo-Hyun Lee, Yung-Jae Kim, Hum-Young Baek, Young Jun Kim, Woo Jin Jun & Ho-Geun Yoon. (2011) Neuroprotective effects of Eriobotrya japonica against ?-amyloid-induced oxidative stress and memory impairment. Food and Chemical Toxicology 49:4, pages 780-784.
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Kazuyo Muramoto, Rong-Dan Quan, Toshiharu Namba, Shojiro Kyotani, Mitsuhiko Miyamura, Yutaka Nishioka, Keiichi Tonosaki, Yoshinori L. Doi & Hideto Kaba. (2010) Ameliorative effects of Eriobotrya japonica seed extract on cellular aging in cultured rat fibroblasts. Journal of Natural Medicines 65:2, pages 254-261.
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J. Eliza, P. Daisy & S. Ignacimuthu. (2010) Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm.. Chemico-Biological Interactions 188:3, pages 467-472.
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Yoshinori Okada, Mizue Okada & Yumi Sagesaka. (2010) Screening of Dried Plant Seed Extracts for Adiponectin Production Activity and Tumor Necrosis Factor-Alpha Inhibitory Activity on 3T3-L1 Adipocytes. Plant Foods for Human Nutrition 65:3, pages 225-232.
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Guangchen SUN, Yingqin LIU, Jinling ZHU, Miki IGUCHI, Saburo YOSHIOKA, Mitsuhiko MIYAMURA & Shojiro KYOTANI. (2010) Immunomodulatory Effect of Eriobotrya japonica Seed Extract on Allergic Dermatitis Rats. Journal of Nutritional Science and Vitaminology 56:2, pages 145-149.
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H. L?J. Chen, W.L. Li, B.R. Ren, J.L. Wu, H.Y. Kang, H.Q. Zhang, A. Adams & N. De Kimpe. (2009) Hypoglycemic and hypolipidemic effects of the total triterpene acid fraction from Folium Eriobotryae. Journal of Ethnopharmacology 122:3, pages 486-491.
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