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Original Articles

Methadone Dose and Retention During Treatment of Heroin Addicts with Axis I Psychiatric Comorbidity

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Pages 29-41 | Published online: 12 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (14)

Dorcas Rosaley Prakaschandra, Andrew Scheibe, Monique Marks & Datshana Prakesh Naidoo. (2023) Assessing cardiac safety among clients receiving methadone as part of opioid agonist maintenance therapy (OAMT) in Durban, South Africa. Journal of Addictive Diseases 41:1, pages 82-90.
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Giulio Perugi, Alessandro Pallucchini, Salvatore Rizzato, Pietro De Rossi, Gabriele Sani, Angelo GI Maremmani, Vito Pinzone & Icro Maremmani. (2019) Pharmacotherapeutic strategies for the treatment of attention-deficit hyperactivity (ADHD) disorder with comorbid substance-use disorder (SUD). Expert Opinion on Pharmacotherapy 20:3, pages 343-355.
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Maurice Dematteis, Marc Auriacombe, Oscar D’Agnone, Lorenzo Somaini, Néstor Szerman, Richard Littlewood, Farrukh Alam, Hannu Alho, Amine Benyamina, Julio Bobes, Jean Pierre Daulouede, Claudio Leonardi, Icro Maremmani, Marta Torrens, Stephan Walcher & Michael Soyka. (2017) Recommendations for buprenorphine and methadone therapy in opioid use disorder: a European consensus. Expert Opinion on Pharmacotherapy 18:18, pages 1987-1999.
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Angelo Giovanni Icro Maremmani, Fabio Rugani, Silvia Bacciardi, Luca Rovai, Enrico Massimetti, Denise Gazzarrini, Liliana Dell’Osso & Icro Maremmani. (2015) Differentiating Between the Course of Illness in Bipolar 1 and Chronic-Psychotic Heroin-Dependent Patients at Their First Agonist Opioid Treatment. Journal of Addictive Diseases 34:1, pages 43-54.
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Einat Peles, Shaul Schreiber, Yoav Domany & Miriam Adelson. (2014) Impact of lifetime psychiatric diagnosis on long-term retention and survival of former opiate addicts in methadone maintenance treatment. The World Journal of Biological Psychiatry 15:8, pages 629-635.
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David Potik, Einat Peles, Yahli Abramsohn, Miriam Adelson & Shaul Schreiber. (2014) The Relationship Between Vulnerable Attachment Style, Psychopathology, Drug Abuse, and Retention in Treatment Among Methadone Maintenance Treatment Patients. Journal of Psychoactive Drugs 46:4, pages 325-333.
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Michael Soyka, Henry R. Kranzler, Wim van den Brink, John Krystal, Hans-Jürgen Möller & Siegfried Kasper. (2011) The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Substance Use and Related Disorders. Part 2: Opioid dependence. The World Journal of Biological Psychiatry 12:3, pages 160-187.
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Angelo Giovanni Icro Maremmani, Liliana Dell’Osso, Matteo Pacini, Dina Popovic, Luca Rovai, Marta Torrens, Giulio Perugi & Icro Maremmani. (2011) Dual Diagnosis and Chronology of Illness in Treatment-Seeking Italian Patients Dependent on Heroin. Journal of Addictive Diseases 30:2, pages 123-135.
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Michael Mancino, Geoffrey Curran, Xiaotong Han, Elise Allee, Keith Humphreys & Brenda M. Booth. (2010) Predictors of Attrition from a National Sample of Methadone Maintenance Patients. The American Journal of Drug and Alcohol Abuse 36:3, pages 155-160.
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Dirk Wedekind, Stefan Jacobs, Iris Karg, Christel Luedecke, Udo Schneider, Konrad Cimander, Pierre Baumann, Eckart Ruether, Wolfgang Poser & Ursula Havemann-Reinecke. (2010) Psychiatric comorbidity and additional abuse of drugs in maintenance treatment with l- and d,l-methadone. The World Journal of Biological Psychiatry 11:2-2, pages 390-399.
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Kristi-Ann Villagonzalo, Seetal Dodd, Felicity Ng, Stephen Mihaly, Amy Langbein & Michael Berk. (2010) The utility of the Mood Disorders Questionnaire as a screening tool in a methadone maintenance treatment program. International Journal of Psychiatry in Clinical Practice 14:2, pages 150-153.
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Petra S. Meier & Christine Barrowclough. (2009) Mental health problems: Are they or are they not a risk factor for dropout from drug treatment? A systematic review of the evidence. Drugs: Education, Prevention and Policy 16:1, pages 7-38.
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PeterL. Tenore. (2008) Psychotherapeutic Benefits of Opioid Agonist Therapy. Journal of Addictive Diseases 27:3, pages 49-65.
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Giuseppe Carrà & Massimo Clerici. (2006) Dual Diagnosis—Policy and Practice in Italy. American Journal on Addictions 15:2, pages 125-130.
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Articles from other publishers (41)

Anees Bahji, Gabriel Bastien, Paxton Bach, JinCheol Choi, Bernard Le Foll, Ron Lim, Didier Jutras-Aswad & M. Eugenia Socias. (2023) The Association Between Self-Reported Anxiety and Retention in Opioid Agonist Therapy: Findings From a Canadian Pragmatic Trial. The Canadian Journal of Psychiatry.
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Icro Maremmani, Matteo Pacini & Angelo G. I. MaremmaniIcro Maremmani, Matteo Pacini & Angelo G. I. Maremmani. 2023. Dual Disorder Heroin Addicts. Dual Disorder Heroin Addicts 109 163 .
Icro Maremmani, Matteo Pacini & Angelo G. I. MaremmaniIcro Maremmani, Matteo Pacini & Angelo G. I. Maremmani. 2023. Dual Disorder Heroin Addicts. Dual Disorder Heroin Addicts 91 108 .
Icro Maremmani, Matteo Pacini & Angelo G. I. MaremmaniIcro Maremmani, Matteo Pacini & Angelo G. I. Maremmani. 2023. Dual Disorder Heroin Addicts. Dual Disorder Heroin Addicts 1 37 .
Matteo Pacini, Angelo G. I. Maremmani & Icro Maremmani. (2020) The Conceptual Framework of Dual Disorders and Its Flaws. Journal of Clinical Medicine 9:7, pages 2098.
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Mehmet Sofuoglu, Elise E. DeVito & Kathleen M. Carroll. (2018) Pharmacological and Behavioral Treatment of Opioid Use Disorder. Psychiatric Research and Clinical Practice 1:1, pages 4-15.
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Angelo Maremmani, Matteo Pacini & Icro Maremmani. (2019) What we have learned from the Methadone Maintenance Treatment of Dual Disorder Heroin Use Disorder patients. International Journal of Environmental Research and Public Health 16:3, pages 447.
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Angelo G. I. Maremmani, Alessandro Pallucchini, Luca Rovai, Silvia Bacciardi, Vincenza Spera, Marco Maiello, Giulio Perugi & Icro Maremmani. (2018) The long-term outcome of patients with heroin use disorder/dual disorder (chronic psychosis) after admission to enhanced methadone maintenance. Annals of General Psychiatry 17:1.
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Lakshmi N Yatham, Sidney H Kennedy, Sagar V Parikh, Ayal Schaffer, David J Bond, Benicio N Frey, Verinder Sharma, Benjamin I Goldstein, Soham Rej, Serge Beaulieu, Martin Alda, Glenda MacQueen, Roumen V Milev, Arun Ravindran, Claire O'Donovan, Diane McIntosh, Raymond W Lam, Gustavo Vazquez, Flavio Kapczinski, Roger S McIntyre, Jan Kozicky, Shigenobu Kanba, Beny Lafer, Trisha Suppes, Joseph R Calabrese, Eduard Vieta, Gin Malhi, Robert M Post & Michael Berk. (2018) Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disorders 20:2, pages 97-170.
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Lantie Jorandby-Quinones, Ellen Edens & Robert A. Rosenheck. 2018. Military and Veteran Mental Health. Military and Veteran Mental Health 307 333 .
Matteo Pacini & Icro Maremmani. (2017) What Have We Learned From the Agonist Opioid Treatment of Dual Disorder Heroin Addicts?. Addictive Disorders & Their Treatment 16:4, pages 164-174.
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Noa Krawczyk, Kenneth A. Feder, Brendan Saloner, Rosa M. Crum, Marc Kealhofer & Ramin Mojtabai. (2017) The association of psychiatric comorbidity with treatment completion among clients admitted to substance use treatment programs in a U.S. national sample. Drug and Alcohol Dependence 175, pages 157-163.
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Angelo G. I. Maremmani, Pier Paolo Pani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano & Icro Maremmani. (2016) The impact of psychopathological subtypes on retention rate of patients with substance use disorder entering residential therapeutic community treatment. Annals of General Psychiatry 15:1.
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Carlos Roncero, Carmen Barral, Laia Rodríguez-Cintas, Jesús Pérez-Pazos, Nieves Martinez-Luna, Miguel Casas, Marta Torrens & Lara Grau-López. (2016) Psychiatric comorbidities in opioid-dependent patients undergoing a replacement therapy programme in Spain: The PROTEUS study. Psychiatry Research 243, pages 174-181.
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Debasish Basu, Bhagyalakshmi Nanjayya Subodh, Kavita Nagpal & Sudhir Mahajan. (2016) Bipolar spectrum disorders in substance use disorders. Asian Journal of Psychiatry 21, pages 33-36.
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Stuart Gore, Julio Mendoza & Jaime Delgadillo. (2015) Multiple obstacles to psychological care from the viewpoint of addiction service users. Advances in Dual Diagnosis 8:3, pages 129-140.
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Angelo GI Maremmani, Luca Rovai, Fabio Rugani, Silvia Bacciardi, Enrico Massimetti, Denise Gazzarrini, Liliana Dell׳Osso, Fengyi Tang, Hagop S. Akiskal & Icro Maremmani. (2015) Chronology of illness in dual diagnosis heroin addicts: The role of mood disorders. Journal of Affective Disorders 179, pages 156-160.
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Sameer Hassamal, Antony Fernandez, Hossein Moradi Rekabdarkolaee & Ananda Pandurangi. (2015) QTc Prolongation in Veterans With Heroin Dependence on Methadone Maintenance Treatment. International Journal of High Risk Behaviors and Addiction 4:2.
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Angelo Giovanni Icro Maremmani, Silvia Bacciardi, Nicole D. Gehring, Luca Cambioli, Christian Schütz, Hagop S. Akiskal, Kerry Jang & Michael Krausz. (2015) The impact of mood symptomatology on pattern of substance use among homeless. Journal of Affective Disorders 176, pages 164-170.
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Georgios Moussas, Irene Fanouraki, Argiro Pachi, Arezina Asomatou, Olga Drylli, Georgios Paschalakis, Athanasios Tselebis, Konstantinos Giotakis, Dionisios Bratis, Georgios Dermatis & Meni Malliori. (2015) Comorbid Psychopathology and Alcohol Use Patterns among Methadone Maintenance Treatment Patients. Journal of Addiction 2015, pages 1-10.
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Angelo Giovanni Icro Maremmani, Luca Rovai, Silvia Bacciardi, Fabio Rugani, Matteo Pacini, Pier Paolo Pani, Liliana Dell' Osso, Hagop Akiskal & Icro Maremmani. (2013) The long-term outcomes of heroin dependent-treatment-resistant patients with bipolar 1 comorbidity after admission to enhanced methadone maintenance. Journal of Affective Disorders 151:2, pages 582-589.
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Angelo Giovanni Icro Maremmani, Silvia Bacciardi, Luca Rovai, Fabio Rugani, Liliana Dell’Osso & Icro Maremmani. (2013) Natural History of Addiction in Psychotic Heroin-addicted Patients at Their First Agonist Opioid Treatment. Addictive Disorders & Their Treatment 12:1, pages 31-39.
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Hsin-Ya Lee, Jih-Heng Li, Yuh-Ling Sheu, Hsin-Pei Tang, Wei-Chiao Chang, Tze-Chun Tang, Yi-Chun Yeh, Shing-Yaw Wang & Ray-H. Liu. (2013) Moving toward Personalized Medicine in the Methadone Maintenance Treatment Program: A Pilot Study on the Evaluation of Treatment Responses in Taiwan. BioMed Research International 2013, pages 1-11.
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Céline Eiden, Yves Leglise, Béatrice Clarivet, Jean-Pierre Blayac & Hélène Peyrière. (2012) Co-morbidités psychiatriques associées à des fortes posologies de méthadone (> 100 mg/j) : analyse rétrospective d’une cohorte de patients traités. Therapies 67:3, pages 223-230.
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G. Gerra, E. Saenz, A. Busse, I. Maremmani, R. Ciccocioppo, A. Zaimovic, M.L. Gerra, M. Amore, M. Manfredini, C. Donnini & L. Somaini. (2011) Supervised daily consumption, contingent take-home incentive and non-contingent take-home in methadone maintenance. Progress in Neuro-Psychopharmacology and Biological Psychiatry 35:2, pages 483-489.
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Angelo Maremmani, Luca Rovai, Pier Pani, Matteo Pacini, Francesco Lamanna, Fabio Rugani, Elisa Schiavi, Liliana Dell'Osso & Icro Maremmani. (2011) Do methadone and buprenorphine have the same impact on psychopathological symptoms of heroin addicts?. Annals of General Psychiatry 10:1, pages 17.
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Iain C. Anthony, Katherine E. Norrby, Tommy Dingwall, Frances W. Carnie, Tracey Millar, Juan Carlos Arango, Roy Robertson & Jeanne E. Bell. (2010) Predisposition to accelerated Alzheimer-related changes in the brains of human immunodeficiency virus negative opiate abusers. Brain 133:12, pages 3685-3698.
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Pier Paolo Pani, Icro Maremmani, Emanuela Trogu, Gian Luigi Gessa, Pedro Ruiz & Hagop Souren Akiskal. (2010) Delineating the psychic structure of substance abuse and addictions: Should anxiety, mood and impulse-control dysregulation be included?. Journal of Affective Disorders 122:3, pages 185-197.
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Michael J. Mancino, Janette McGaugh, Zachary Feldman, James Poling & Alison Oliveto. (2010) Effect of PTSD Diagnosis and Contingency Management Procedures on Cocaine Use in Dually Cocaine‐ and Opioid‐Dependent Individuals Maintained on LAAM: A Retrospective Analysis. The American Journal on Addictions 19:2, pages 169-177.
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C. Roncero, C. López-Ortiz, M. Rodríguez-Pascual & L. Grau-López. (2009) Paciente bipolar dual: un reto terapéutico. Trastornos Adictivos 11:2, pages 131-137.
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Icro Maremmani, Matteo Pacini, Pier Paolo Pani, Giulio Perugi, Joseph Deltito & Hagop Akiskal. (2007) The mental status of 1090 heroin addicts at entry into treatment: should depression be considered a 'dual diagnosis'?. Annals of General Psychiatry 6:1.
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Icro Maremmani, Giulio Perugi, Matteo Pacini & Hagop S. Akiskal. (2006) Toward a unitary perspective on the bipolar spectrum and substance abuse: Opiate addiction as a paradigm. Journal of Affective Disorders 93:1-3, pages 1-12.
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Icro Maremmani, Matteo Pacini, Antonio Lazzeri, Giulio Perugi & Joseph Deltito. (2006) Concurrent Abuse of Cannabis Is Associated with a Shorter Duration of Hospitalization in Treatment-Resistant Psychotic Bipolar Inpatients Treated with Clozapine. Addictive Disorders & Their Treatment 5:1, pages 1-7.
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Icro Maremmani, Matteo Pacini, Giulio Perugi & Hagop S Akiskal. (2004) Addiction and the Bipolar Spectrum. Addictive Disorders & Their Treatment 3:4, pages 156-164.
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