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Original Articles

Therapeutic Drug Monitoring in Methadone Maintenance

Choosing a Matrix

, &
Pages 55-73 | Published online: 12 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Omar Henriquez-Gonzalez & Robert Patton. (2013) Prevalence of tobacco, cocaine and alcohol use amongst patients attending for methadone-maintenance therapy in a rural setting. Journal of Substance Use 18:5, pages 340-348.
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Debra F. Hobbins. (2010) Case Report: Methadone Maintenance Dose of 1200 mg/day in an Ultra-rapid Metabolizer. Journal of Addictions Nursing 21:1, pages 22-36.
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Kyle R. Dyer, Kyle R. Dyer, Catherine Wilkinson, Kyle R. Dyer & Catherine Wilkinson. (2008) The detection of illicit drugs in oral fluid: another potential strategy to reduce illicit drug-related harm. Drug and Alcohol Review 27:1, pages 99-107.
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Articles from other publishers (20)

Xiao-ming Wang, Jigong Wang, Valentina Fokina, Svetlana Patrikeeva, Erik Rytting, Mahmoud S. Ahmed, Jun-Ho La & Tatiana Nanovskaya. (2022) Effect of deuteration on the single dose pharmacokinetic properties and postoperative analgesic activity of methadone. Drug Metabolism and Pharmacokinetics 47, pages 100477.
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Baharak Davari, Nidhi Kotecha, Claudia F. Clavijo, James J. ThomasRachael Rzasa-Lynn, Jeffrey L. GalinkinUwe Christians & Cristina Sempio. (2020) A Sensitive LC-MS/MS Assay for the Quantification of Methadone and its Metabolites in Dried Blood Spots: Comparison With Plasma. Therapeutic Drug Monitoring 42:1, pages 118-128.
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Rani George, Alison Haywood, Phillip Good, Stefanie Hennig, Sohil Khan, Ross Norris & Janet Hardy. (2017) Can Saliva and Plasma Methadone Concentrations Be Used for Enantioselective Pharmacokinetic and Pharmacodynamic Studies in Patients With Advanced Cancer?. Clinical Therapeutics 39:9, pages 1840-1848.
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. (2017) Appropriate Use of Drug Testing in Clinical Addiction Medicine. Journal of Addiction Medicine 11:1, pages 1-56.
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Long Hoang Nguyen, Lan Huong Thi Nguyen, Victoria L. Boggiano, Canh Dinh Hoang, Hung Van Nguyen, Huong Thi Le, Hai Quan Le, Tho Dinh Tran, Bach Xuan Tran, Carl A. Latkin, Nabil Zary & Minh Thuc Thi Vu. (2017) Quality of life and healthcare service utilization among methadone maintenance patients in a mountainous area of Northern Vietnam. Health and Quality of Life Outcomes 15:1.
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Hamid Abousaidi, Omid Rezahosseini, Reza Bidaki, Mahmood Sheikh Fathollahi, Hamid Reza Goodarzi Nejad, Golam Hossein Hassan Shahi, Maryam Sahraei, Shila Jalalpoor & Mina Abousaidi. (2016) Viral and Psychiatric Disorders in Methadone Maintenance Therapy (MMT) Clients. Thrita 5:4.
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Rani George, Michael Lobb, Alison Haywood, Sohil Khan, Janet Hardy, Phillip Good, Stefanie Hennig & Ross Norris. (2016) Quantitative determination of the enantiomers of methadone in human plasma and saliva by chiral column chromatography coupled with mass spectrometric detection. Talanta 149, pages 142-148.
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Sudeep R. Bista, Alison Haywood, Ross Norris, Phillip Good, Angela Tapuni, Michael Lobb & Janet Hardy. (2015) Saliva versus Plasma for Pharmacokinetic and Pharmacodynamic Studies of Fentanyl in Patients with Cancer. Clinical Therapeutics 37:11, pages 2468-2475.
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Andrea Trescot, Natalia Murinova & Daniel Krashin. 2015. Substance Abuse. Substance Abuse 301 310 .
Shiau Hui Diong, Nor Shuhadah Mohd Yusoff, Maw Shin Sim, Raja Elina Raja Aziddin, Zamri Chik, Poppy Rajan, Rusdi Abdul Rashid, Norliza Chemi & Zahurin Mohamed. (2014) Quantitation of Methadone and Metabolite in Patients under Maintenance Treatment. Journal of Analytical Toxicology 38:9, pages 660-666.
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Sudeep R. Bista, Michael Lobb, Alison Haywood, Janet Hardy, Angela Tapuni & Ross Norris. (2014) Development, validation and application of an HPLC–MS/MS method for the determination of fentanyl and nor-fentanyl in human plasma and saliva. Journal of Chromatography B 960, pages 27-33.
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Melissa B. Weimer, P. Todd Korthuis, George S. Behonick & Martha J. Wunsch. (2011) The Source of Methadone in Overdose Deaths in Western Virginia in 2004. Journal of Addiction Medicine 5:3, pages 188-202.
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Laloup Marleen, Samyn Nele & De Boeck Gert. 2009. Wiley Encyclopedia of Forensic Science. Wiley Encyclopedia of Forensic Science.
Marleen Laloup, Gert De Boeck & Nele Samyn. 2008. Forensic Science. Forensic Science 653 697 .
John M. Corkery, Fabrizio Schifano, A. Hamid Ghodse & Adenekan Oyefeso. (2004) The effects of methadone and its role in fatalities. Human Psychopharmacology: Clinical and Experimental 19:8, pages 565-576.
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R Brown, C Kraus, M Fleming & S Reddy. (2004) Methadone: applied pharmacology and use as adjunctive treatment in chronic pain. Postgraduate Medical Journal 80:949, pages 654-659.
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Yvonnick B??zie, Val??rie Talon, Agn??s Lillo, Christian Illier, Eliane Billaud, Patrice Prognon & Pierre Boutouyrie. (2004) Compliance with Methadone-Based Substitutive Treatment. Therapeutic Drug Monitoring 26:3, pages 271-276.
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Joseph A. Kim, Kelly A. Pollak, Gregory O. Hjelmstad & Howard L. Fields. (2004) A single cocaine exposure enhances both opioid reward and aversion through a ventral tegmental area-dependent mechanism. Proceedings of the National Academy of Sciences 101:15, pages 5664-5669.
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Avram Goldstein & Byron W. Brown. (2003) Urine testing in methadone maintenance treatment: applications and limitations. Journal of Substance Abuse Treatment 25:2, pages 61-63.
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Xiaoming Wang, Jigong Wang, Valentina Fokina, Svetlana Patrikeeva, Erik Rytting, S. Mahmoud, Jun-Ho La & Tatiana Nanovskaya. (2022) Effect of Deuteration on Pharmacokinetic Properties and Postoperative Analgesic Activity of Methadone. SSRN Electronic Journal.
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