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Journal of Addictive Diseases Volume 23, 2004 - Issue 1
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Original Articles

An Open-Label Pilot Study of Methylphenidate in the Treatment of Cocaine Dependent Patients with Adult Attention Deficit/ Hyperactivity Disorder

Eugene C. Somoza MD, PhD, CinARC Cincinnati VA/UC NIDA MDRU, VA Medical Center, 3200 Vine Street, Cincinnati, OH, 45220, USA; Psychiatry Department, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH, 45267-0559, USA
,
Theresa M. Winhusen PhD Cincinnati VA/UC NIDA MDRU, VA Medical Center, 3200 Vine Street, Cincinnati, OH, 45220, USA; Psychiatry Department, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH, 45267-0559, USA
,
T. Peter Bridge MD National Institute on Drug Abuse, Division of Treatment, Research and Development, 6001 Executive Boulevard, Room 4123, MSC 9551, Bethesda, MD, 20892-9551, USA
,
John P. Rotrosen MD New York University School of Medicine and VHA New York Harbor Healthcare System, 423 East 23rd Street, New York, NY, 10010, USA
,
Douglas G. Vanderburg MD New York University School of Medicine and VHA New York Harbor Healthcare System, 423 East 23rd Street, New York, NY, 10010, USA
,
Judy M. Harrer PhD Cincinnati VA/UC NIDA MDRU, VA Medical Center, 3200 Vine Street, Cincinnati, OH, 45220, USA; Psychiatry Department, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH, 45267-0559, USA
,
Juris P. Mezinskis PhD Cincinnati VA/UC NIDA MDRU, VA Medical Center, 3200 Vine Street, Cincinnati, OH, 45220, USA; Psychiatry Department, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH, 45267-0559, USA
,
Margaret A. Montgomery RN National Institute on Drug Abuse, Division of Treatment, Research and Development, 6001 Executive Boulevard, Room 4123, MSC 9551, Bethesda, MD, 20892-9551, USA
,
Domenic A. Ciraulo MD Department of Psychiatry, MDRU, VA Boston Healthcare System, Boston University School of Medicine, 720 Harrison Avenue, Boston, MA, 02118, USA
,
Lawson R. Wulsin MD Cincinnati VA/UC NIDA MDRU, VA Medical Center, 3200 Vine Street, Cincinnati, OH, 45220, USA; Psychiatry Department, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH, 45267-0559, USA
&
Jera A. Barrett MD Cincinnati VA/UC NIDA MDRU, VA Medical Center, 3200 Vine Street, Cincinnati, OH, 45220, USA
 show all
Pages 77-92 | Published online: 12 Oct 2008

Citations (36)

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Marc Vogel, Patricia Bucher, Johannes Strasser, Matthias E. Liechti, Stephan Krähenbühl & Kenneth M. Dürsteler. (2016) Similar and Different? Subjective Effects of Methylphenidate and Cocaine in Opioid-Maintained Patients. Journal of Psychoactive Drugs 48:2, pages 93-100.
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Kenneth M Dürsteler, Eva-Maria Berger, Johannes Strasser, Carlo Caflisch, Jochen Mutschler, Marcus Herdener & Marc Vogel. (2015) Clinical potential of methylphenidate in the treatment of cocaine addiction: a review of the current evidence. Substance Abuse and Rehabilitation 6, pages 61-74.
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Christopher D Verrico, Colin N Haile, Thomas F Newton, Thomas R Kosten & Richard De La Garza. (2013) Pharmacotherapeutics for substance-use disorders: a focus on dopaminergic medications. Expert Opinion on Investigational Drugs 22:12, pages 1549-1568.
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Estate Sokhadze, ChristopherM. Stewart, Allan Tasman, Robert Daniels & David Trudeau. (2011) Review of Rationale for Neurofeedback Application in Adolescent Substance Abusers with Comorbid Disruptive Behavioral Disorders. Journal of Neurotherapy 15:3, pages 232-261.
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Thomas Babcock & Craig S. Ornstein. (2009) Comorbidity and its Impact in Adult Patients with Attention-Deficit/Hyperactivity Disorder: A Primary Care Perspective. Postgraduate Medicine 121:3, pages 73-82.
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FrancesR. Levin, JohnJ. Mariani, Alex Secora, Daniel Brooks, WendyY. Cheng, Adam Bisaga, Edward Nunes, Efrat Aharonovich, Wilfrid Raby & Grace Hennessy. (2009) Atomoxetine Treatment for Cocaine Abuse and Adult Attention Deficit/Hyperactivity Disorder (ADHD): A Preliminary Open Trial. Journal of Dual Diagnosis 5:1, pages 41-56.
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James Shearer. (2008) The principles of agonist pharmacotherapy for psychostimulant dependence. Drug and Alcohol Review 27:3, pages 301-308.
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John J. Mariani, Jonathan Horey, Adam Bisaga, Efrat Aharonovich, Wilfrid Raby, Wendy Y. Cheng, Edward Nunes & Frances R. Levin. (2008) Antisocial Behavioral Syndromes in Cocaine and Cannabis Dependence. The American Journal of Drug and Alcohol Abuse 34:4, pages 405-414.
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John J. Mariani, John J. Mariani & Frances R. Levin. (2007) Treatment Strategies for Co-Occurring ADHD and Substance Use Disorders. American Journal on Addictions 16:sup1, pages 45-56.
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Articles from other publishers (27)

Frances R. Levin, C. Jean Choi, Martina Pavlicova, John J. Mariani, Amy Mahony, Daniel J. Brooks, Edward V. Nunes & John Grabowski. (2018) How treatment improvement in ADHD and cocaine dependence are related to one another: A secondary analysis. Drug and Alcohol Dependence 188, pages 135-140.
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Benedikt Fischer, Peter Blanken, Dartiu Da Silveira, Andrea Gallassi, Elliot M. Goldner, Jürgen Rehm, Mark Tyndall & Evan Wood. (2015) Effectiveness of secondary prevention and treatment interventions for crack-cocaine abuse: A comprehensive narrative overview of English-language studies. International Journal of Drug Policy 26:4, pages 352-363.
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Frances R. Levin. 2015. Textbook of Addiction Treatment: International Perspectives. Textbook of Addiction Treatment: International Perspectives 2035 2062 .
Timothy E. Wilens & Nicholas R. Morrison. 2015. Attention-Deficit Hyperactivity Disorder in Adults and Children. Attention-Deficit Hyperactivity Disorder in Adults and Children 111 122 .
Martin A. Katzman & Tia Sternat. (2014) A Review of OROS Methylphenidate (Concerta®) in the Treatment of Attention-Deficit/Hyperactivity Disorder. CNS Drugs 28:11, pages 1005-1033.
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Frieda Matthys, Steven Stes, Wim van den Brink, Peter Joostens, David Möbius, Sabine Tremmery & Bernard Sabbe. (2014) Guideline for Screening, Diagnosis and Treatment of ADHD in Adults with Substance Use Disorders. International Journal of Mental Health and Addiction 12:5, pages 629-647.
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José Pérez de los Cobos, Núria Siñol, Víctor Pérez & Joan Trujols. (2014) Pharmacological and clinical dilemmas of prescribing in co-morbid adult attention-deficit/hyperactivity disorder and addiction. British Journal of Clinical Pharmacology 77:2, pages 337-356.
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Cleo L. Crunelle, Wim van den Brink, Dick J. Veltman, Katelijne van Emmerik-van Oortmerssen, Geert Dom, Robert A. Schoevers & Jan Booij. (2013) Low dopamine transporter occupancy by methylphenidate as a possible reason for reduced treatment effectiveness in ADHD patients with cocaine dependence. European Neuropsychopharmacology 23:12, pages 1714-1723.
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Guido A. van Wingen, Wim van den Brink, Dick J. Veltman, Lianne Schmaal, Geert Dom, Jan Booij & Cleo L. Crunelle. (2013) Reduced striatal brain volumes in non-medicated adult ADHD patients with comorbid cocaine dependence. Drug and Alcohol Dependence 131:3, pages 198-203.
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P. W. Czoty, S. E. Martelle, R. W. Gould & M. A. Nader. (2013) Effects of Chronic Methylphenidate on Cocaine Self-Administration under a Progressive-Ratio Schedule of Reinforcement in Rhesus Monkeys. Journal of Pharmacology and Experimental Therapeutics 345:3, pages 374-382.
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Esther Sobanski, Georgios Paslakis, Michael Schredl, Stephanie Daffner & Barbara Alm. 2013. ADHD in Adults. ADHD in Adults 137 154 .
Timothy E Wilens & Nicholas R Morrison. (2012) Substance-use disorders in adolescents and adults with ADHD: focus on treatment. Neuropsychiatry 2:4, pages 301-312.
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Colin N. Haile, James J. MahoneyIIIIII, Thomas F. Newton & Richard De La GarzaIIII. (2012) Pharmacotherapeutics directed at deficiencies associated with cocaine dependence: Focus on dopamine, norepinephrine and glutamate. Pharmacology & Therapeutics 134:2, pages 260-277.
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Héloïse Delavenne, Nicolas Ballon, Aimé Charles-Nicolas, Frederico Duarte Garcia, Florence Thibaut & Jérôme Lacoste. (2011) Attention Deficit Hyperactivity Disorder Is Associated With a More Severe Pattern of Cocaine Consumption in Cocaine Users From French West Indies. Journal of Addiction Medicine 5:4, pages 284-288.
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Karen D. Ersche & Trevor W. Robbins. 2011. Neuroimaging in Addiction. Neuroimaging in Addiction 7 35 .
Maija Konstenius, Nitya Jayaram-Lindstr?m, Olof Beck & Johan Franck. (2010) Sustained release methylphenidate for the treatment of ADHD in amphetamine abusers: A pilot study. Drug and Alcohol Dependence 108:1-2, pages 130-133.
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G. Paslakis, F. Kiefer, A. Diehl, B. Alm & E. Sobanski. (2010) MethylphenidatMethylphenidate. Der Nervenarzt 81:3, pages 277-288.
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Anne Goossensen, Geurt van der Glind, Pieter-Jan Carpentier, Riek Wijsen, Daniëlle van Duin & Sandra Kooij. (2007) Herkenning en intramurale behandeling van ADHD in de verslavingszorg. Verslaving 3:4, pages 148-154.
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Christine Darredeau, Sean P. Barrett, Bianca Jardin & Robert O. Pihl. (2007) Patterns and predictors of medication compliance, diversion, and misuse in adult prescribed methylphenidate users. Human Psychopharmacology: Clinical and Experimental 22:8, pages 529-536.
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Xavier Castells, Miguel Casas, Xavier Vidal, Rosa Bosch, Carlos Roncero, Josep Antoni Ramos‐Quiroga & Dolors Capellà. (2007) Efficacy of central nervous system stimulant treatment for cocaine dependence: a systematic review and meta‐analysis of randomized controlled clinical trials. Addiction 102:12, pages 1871-1887.
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Frank J. Vocci & Nathan M. Appel. (2007) Approaches to the development of medications for the treatment of methamphetamine dependence. Addiction 102, pages 96-106.
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Frances R. Levin, Suzette M. Evans, Daniel J. Brooks & Fatima Garawi. (2007) Treatment of cocaine dependent treatment seekers with adult ADHD: Double-blind comparison of methylphenidate and placebo. Drug and Alcohol Dependence 87:1, pages 20-29.
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G. A. Wiesbeck & K. Dürsteler-MacFarland. (2006) Neue Entwicklungen in der Pharmakotherapie der KokainabhängigkeitNew developments in the pharmacotherapy of cocaine dependence. Der Nervenarzt 77:9, pages 1064-1070.
Crossref
M. Anne Goossensen, Geurt van de Glind, Pieter-Jan Carpentier, Riek M.A. Wijsen, Daniëlle van Duin & J.J. Sandra Kooij. (2006) An intervention program for ADHD in patients with substance use disorders: Preliminary results of a field trial. Journal of Substance Abuse Treatment 30:3, pages 253-259.
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Frances R. Levin, Suzette M. Evans, Daniel J. Brooks, Aparna S. Kalbag, Fatima Garawi & Edward V. Nunes. (2006) Treatment of methadone-maintained patients with adult ADHD: Double-blind comparison of methylphenidate, bupropion and placebo. Drug and Alcohol Dependence 81:2, pages 137-148.
Crossref
Pieter J. Carpentier, Cor A. J. De Jong, Boukje A. G. Dijkstra, Cor A. G. Verbrugge & Paul F. M. Krabbe. (2005) A controlled trial of methylphenidate in adults with attention deficit/hyperactivity disorder and substance use disorders. Addiction 100:12, pages 1868-1874.
Crossref
John Grabowski, James Shearer, John Merrill & S. Stevens Negus. (2004) Agonist-like, replacement pharmacotherapy for stimulant abuse and dependence. Addictive Behaviors 29:7, pages 1439-1464.
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