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Research Article

Therapeutic Drug Monitoring in HIV Treatment: A Literature Review

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Pages 59-69 | Published online: 02 Feb 2015

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Peter K. Olds, Julius P. Kiwanuka, Denis Nansera, Yong Huang, Peter Bacchetti, Chengshi Jin, Monica Gandhi & Jessica E. Haberer. (2015) Assessment of HIV antiretroviral therapy adherence by measuring drug concentrations in hair among children in rural Uganda. AIDS Care 27:3, pages 327-332.
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Kristin H Busse & Scott R Penzak. (2008) Pharmacological enhancement of protease inhibitors with ritonavir: an update. Expert Review of Clinical Pharmacology 1:4, pages 533-545.
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Niamh Higgins, Barry S. Zingman, Judianne Slish, Richard C. Reichman, Margaret A. Fischl, Barbara Gripshover, Kelly Tooley, Naomi Boston, Alan Forrest, Dan Brazeau, Linda M. Catanzaro, Robin DiFrancesco, Francesco Lliguicota, Qing Ma & Gene D. Morse. (2007) Factors Associated with Altered Pharmacokinetics in Substance Users and Non-Substance Users Receiving Lopinavir and Atazanavir. American Journal on Addictions 16:6, pages 488-494.
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Articles from other publishers (24)

Nordiana Binti Rosli, Ha-Jeong Kwon & Ji-Seon Jeong. (2023) Simultaneous quantification method for multiple antiviral drugs in serum using isotope dilution liquid chromatography–tandem mass spectrometry. Journal of Chromatography B 1231, pages 123925.
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Debbie VitalisDebbie Vitalis. 2021. Adherence to Antiretroviral Therapy among Perinatal Women in Guyana. Adherence to Antiretroviral Therapy among Perinatal Women in Guyana 1 54 .
Matthew A. Spinelli, Jessica E. Haberer, Peter R. Chai, Jose Castillo-Mancilla, Peter L. Anderson & Monica Gandhi. (2020) Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions. Current HIV/AIDS Reports 17:4, pages 301-314.
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William M. Gilliland, Nicole R. White, Bryan H. Yam, Joseph N. Mwangi, Heather M. A. Prince, Ann Marie Weideman, Angela D. M. Kashuba & Elias P. Rosen. (2020) Influence of hair treatments on detection of antiretrovirals by mass spectrometry imaging. The Analyst 145:13, pages 4540-4550.
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Linden Lalley-Chareczko, Emily Hiserodt, Ganesh Moorthy, Athena Zuppa, Karam Mounzer & Helen Koenig. (2020) Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide. Frontiers in Pharmacology 11.
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Dario CattaneoSara BaldelliValeria CozziEmilio ClementiDeborah J. E. Marriott & Cristina Gervasoni. (2020) Impact of Therapeutic Drug Monitoring of Antiretroviral Drugs in Routine Clinical Management of People Living With HIV: A Narrative Review. Therapeutic Drug Monitoring 42:1, pages 64-74.
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William M. GillilandJr.Jr., Heather M.A. Prince, Amanda Poliseno, Angela D.M. Kashuba & Elias P. Rosen. (2019) Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging of Human Hair to Characterize Longitudinal Profiles of the Antiretroviral Maraviroc for Adherence Monitoring. Analytical Chemistry 91:16, pages 10816-10822.
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Nhi Phung, Karen Kuncze, Hideaki Okochi, Alexander Louie, Leslie Z. Benet, Igho Ofokotun, David W. Haas, Judith S. Currier, Tariro D. Chawana, Anandi N. Sheth, Peter Bacchetti, Monica Gandhi & Howard Horng. (2018) Development and validation of an assay to analyze atazanavir in human hair via liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry 32:5, pages 431-441.
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Sanjiv M. Baxi, Eric Vittinghoff, Peter Bacchetti, Yong Huang, Kata Chillag, Ryan Wiegand, Peter L. Anderson, Robert Grant, Ruth M. Greenblatt, Susan Buchbinder, Monica Gandhi & Albert Y. Liu. (2018) Comparing pharmacologic measures of tenofovir exposure in a U.S. pre-exposure prophylaxis randomized trial. PLOS ONE 13:1, pages e0190118.
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. (2015) Documento de consenso de GeSIDA/Plan Nacional sobre el Sida respecto al tratamiento antirretroviral en adultos con infección por el virus de la inmunodeficiencia humana (Actualización enero 2015). Enfermedades Infecciosas y Microbiología Clínica 33:8, pages 543.e1-543.e43.
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Guido Antonelli & Ombretta Turriziani. 2015. Practical Handbook of Microbiology, Third Edition. Practical Handbook of Microbiology, Third Edition 197 210 .
Sanjiv M. Baxi, Albert Liu, Peter Bacchetti, Gaudensia Mutua, Eduard J. Sanders, Freddie M. Kibengo, Jessica E. Haberer, James Rooney, Craig W. Hendrix, Peter L. Anderson, Yong Huang, Frances Priddy & Monica Gandhi. (2015) Comparing the Novel Method of Assessing PrEP Adherence/Exposure Using Hair Samples to Other Pharmacologic and Traditional Measures. JAIDS Journal of Acquired Immune Deficiency Syndromes 68:1, pages 13-20.
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. (2014) Documento de consenso de GeSIDA/Plan Nacional sobre el Sida respecto al tratamiento antirretroviral en adultos infectados por el virus de la inmunodeficiencia humana (Actualización enero 2014). Enfermedades Infecciosas y Microbiología Clínica 32:7, pages 446.e1-446.e42.
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Albert Y. Liu, Qiyun Yang, Yong Huang, Peter Bacchetti, Peter L. Anderson, Chengshi Jin, Kathy Goggin, Kristefer Stojanovski, Robert Grant, Susan P. Buchbinder, Ruth M. Greenblatt & Monica Gandhi. (2014) Strong Relationship between Oral Dose and Tenofovir Hair Levels in a Randomized Trial: Hair as a Potential Adherence Measure for Pre-Exposure Prophylaxis (PrEP). PLoS ONE 9:1, pages e83736.
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Monica GandhiQiyun YangPeter BacchettiYong Huang. (2014) Short Communication: A Low-Cost Method for Analyzing Nevirapine Levels in Hair as a Marker of Adherence in Resource-Limited Settings. AIDS Research and Human Retroviruses 30:1, pages 25-28.
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Guido Antonelli & Ombretta Turriziani. (2012) Antiviral therapy: old and current issues. International Journal of Antimicrobial Agents 40:2, pages 95-102.
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Qing Ma, Barry S Zingman, Amneris E Luque, Margaret A Fischl, Barbara M Gripshover, Charles S Venuto, Robin DiFrancesco, Alan Forrest & Gene D Morse. (2011) Therapeutic Drug Monitoring of Protease Inhibitors and Efavirenz in HIV-Infected Individuals With Active Substance-Related Disorders. Therapeutic Drug Monitoring 33:3, pages 309-314.
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Sukhwinder S Lakhman, Qing MaGene D Morse. (2009) Pharmacogenomics of CYP3A : considerations for HIV treatment . Pharmacogenomics 10:8, pages 1323-1339.
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Stefania Notari, Chiara Tommasi, Emanuele Nicastri, Rita Bellagamba, Massimo Tempestilli, Leopoldo Paolo Pucillo, Pasquale Narciso & Paolo Ascenzi. (2009) Simultaneous determination of maraviroc and raltegravir in human plasma by HPLC-UV. IUBMB Life 61:4, pages 470-475.
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Monica Gandhi, Niloufar Ameli, Peter Bacchetti, Stephen J Gange, Kathryn Anastos, Alexandra Levine, Charles L Hyman, Mardge Cohen, Mary Young, Yong Huang & Ruth M Greenblatt. (2009) Protease inhibitor levels in hair strongly predict virologic response to treatment. AIDS 23:4, pages 471-478.
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Michael Neely & Roger Jelliffe. (2013) Practical Therapeutic Drug Management in HIV‐Infected Patients: Use of Population Pharmacokinetic Models Supplemented by Individualized Bayesian Dose Optimization. The Journal of Clinical Pharmacology 48:9, pages 1081-1091.
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Shin-Woo Kim. (2008) Therapeutic Drug Monitoring (TDM) of Antimicrobial Agents. Infection and Chemotherapy 40:3, pages 133.
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Nils Von Hentig, Errol Babacan, Schlomo Staszewski, Martin Stürmer, Hans W Doerr & Jörn Lötsch. (2007) Predictive Factors for Response to a Boosted Dual HIV-Protease Inhibitor Therapy with Saquinavir and Lopinavir in Extensively Pre-Treated Patients. Antiviral Therapy 12:8, pages 1237-1246.
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P. Amariles, N.A. Giraldo & M.J. Faus. (2007) Interacciones medicamentosas en pacientes infectados con el VIH: aproximación para establecer y evaluar su relevancia clínica. Farmacia Hospitalaria 31:5, pages 283-302.
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