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HIV Clinical Trials Volume 6, 2005 - Issue 6
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Original Articles

Prospective, Open-Label Comparative Study of Liver Toxicity in an Unselected Population of HIV-Infected Patients Treated for the First Time with Efavirenz or Nevirapine

Roberto ManfrediDepartment of Clinical and Experimental MedicineDivision of Infectious Diseases, University of Bologna “Alma Mater Studiorum,” S. Orsola Hospital, Bologna, ItalyCorrespondence[email protected]
,
Leonardo CalzaDepartment of Clinical and Experimental MedicineDivision of Infectious Diseases, University of Bologna “Alma Mater Studiorum,” S. Orsola Hospital, Bologna, Italy
&
Francesco ChiodoDepartment of Clinical and Experimental MedicineDivision of Infectious Diseases, University of Bologna “Alma Mater Studiorum,” S. Orsola Hospital, Bologna, Italy
Pages 302-311 | Published online: 02 Feb 2015

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S Hyder Hussaini & Elizabeth A Farrington. (2007) Idiosyncratic drug-induced liver injury: an overview. Expert Opinion on Drug Safety 6:6, pages 673-684.
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Saskia ME Vrouenraets, Ferdinand WNM Wit, Jacqueline van Tongeren & Joep MA Lange. (2007) Efavirenz: a review. Expert Opinion on Pharmacotherapy 8:6, pages 851-871.
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Articles from other publishers (14)

Kiamu Kurosawa, Masataka Nakano, Itsuki Yokoseki, Mai Nagaoka, Seiya Takemoto, Yoshiyuki Sakai, Kaoru Kobayashi, Yasuhiro Kazuki, Tatsuki Fukami & Miki Nakajima. (2023) ncBAF enhances PXR-mediated transcriptional activation in the human and mouse liver. Biochemical Pharmacology 215, pages 115733.
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Kellie J. Goodlet, Monika T. Zmarlicka & Alyssa M. Peckham. (2018) Drug–drug interactions and clinical considerations with co-administration of antiretrovirals and psychotropic drugs. CNS Spectrums 24:03, pages 287-312.
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Lawrence Mbuagbaw, Sara Mursleen, James H Irlam, Alicen B Spaulding, George W Rutherford & Nandi Siegfried. (2016) Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals. Cochrane Database of Systematic Reviews 2016:12.
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C. Padmapriyadarsini, P.K. Bhavani, Alice Tang, Hemanth Kumar, C. Ponnuraja, G. Narendran, Elizabeth Hannah, C. Ramesh, C. Chandrasekar, Christine Wanke & Soumya Swaminathan. (2013) Early changes in hepatic function among HIV–tuberculosis patients treated with nevirapine or efavirenz along with rifampin-based anti-tuberculosis therapy. International Journal of Infectious Diseases 17:12, pages e1154-e1159.
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Ignacio A. EcheniqueJosiah D. Rich. (2013) EFV/FTC/TDF-Associated Hepatotoxicity: A Case Report and Review. AIDS Patient Care and STDs 27:9, pages 493-497.
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P-M Girard, TB Campbell, B Grinsztejn, J Hartikainen, A Rachline, S Nijs & J Witek. (2012) Pooled week 96 results of the phase III DUET-1 and DUET-2 trials of etravirine: further analysis of adverse events and laboratory abnormalities of special interest. HIV Medicine 13:7, pages 427-435.
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Feng Zhou, Gerald F Kominski, Han-Zhu Qian, Jiansheng Wang, Song Duan, Zhiwei Guo & Xinping Zhao. (2011) Expenditures for the care of HIV-infected patients in rural areas in China's antiretroviral therapy programs. BMC Medicine 9:1.
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Lawrence CE Mbuagbaw, James H Irlam, Alicen Spaulding, George W Rutherford & Nandi Siegfried. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Beatriz GrinsztejnGiovanni Di PerriWilliam TownerBrian WoodfallGoedele De SmedtMonika Peeters. (2010) A Review of the Safety and Tolerability Profile of the Next-Generation NNRTI Etravirine. AIDS Research and Human Retroviruses 26:7, pages 725-733.
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Paul J. WeidleDavid MooreJonathan MerminKate BuchaczWilly WereRobert DowningAminah KigoziVincent NdazimaPhilip PetersJohn T. Brooks. (2008) Liver Enzymes Improve Over Twenty-Four Months of First-Line Non-Nucleoside Reverse Transcriptase Inhibitor-Based Therapy in Rural Uganda. AIDS Patient Care and STDs 22:10, pages 787-795.
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Roberto Manfredi & Leonardo Calza. (2007) Safety Issues About Nevirapine Administration in HIV-Infected Pregnant Women. JAIDS Journal of Acquired Immune Deficiency Syndromes 45:3, pages 365-368.
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Carlo Torti, Silvia Costarelli, Annalisa De Silvestri, Eugenia Quiros-Roldan, Giuseppe Lapadula, Giuliana Cologni, Giuseppe Paraninfo, Filippo Castelnuovo, Massimo Puoti & Giampiero Carosi. (2007) Analysis of Severe Hepatic Events Associated with Nevirapine-Containing Regimens. Drug Safety 30:12, pages 1161-1169.
Crossref
Roberto Manfredi & Leonardo Calza. (2006) Nevirapine versus efavirenz in 742 patients: no link of liver toxicity with female sex, and a baseline CD4 cell count greater than 250 cells/μl. AIDS 20:17, pages 2233-2236.
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. (2006) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 15:8.
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