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HIV Clinical Trials Volume 8, 2007 - Issue 4
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Original Articles

High-Dose Lopinavir/Ritonavir in Highly Treatment-Experienced HIV-1 Patients: Efficacy, Safety, and Predictors of Response

Daniel PodzamczerInfectious Disease ServiceHospital Universitari de Bellvitge, Barcelona, Spain
,
Martin S. KingAbbott LaboratoriesAbbott Park, Illinois, USA
,
Cheri E. KleinAbbott LaboratoriesAbbott Park, Illinois, USA
,
Charles FlexnerJohns Hopkins UniversityBaltimore, Maryland, USA
,
Christine KatlamaHôpital de la Pitié-Salpêtrière, Paris, France
,
Diane V. HavlirUniversity of California, San Francisco, USA
,
Scott L. LetendreAntiviral Research CenterUniversity of California, San Diego, USA
,
Joseph J. EronDepartment of Infectious DiseaseUniversity of North Carolina, Chapel Hill, USA
,
Scott C. BrunAbbott LaboratoriesAbbott Park, Illinois, USA
&
Barry BernsteinAbbott LaboratoriesAbbott Park, Illinois, USACorrespondence[email protected]
 show all
Pages 193-204 | Published online: 06 Jan 2015

Citations (15)

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Md. Jamal Hossain & S. M. Abdur Rahman. (2021) Repurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress. Expert Review of Anti-infective Therapy 19:8, pages 1009-1027.
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Patricia Barragan & Daniel Podzamczer. (2008) Lopinavir/ritonavir: a protease inhibitor for HIV-1 treatment. Expert Opinion on Pharmacotherapy 9:13, pages 2363-2375.
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Articles from other publishers (13)

Judith A Aberg, Anthony Mills, Santiago Moreno, Jill Slater, Manyu Prakash & Andrew Clark. (2023) The evolution of clinical study design in heavily treatment-experienced persons with HIV: A critical review. Antiviral Therapy 28:3, pages 135965352311747.
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Md. Hossain, Tabassum Jannat, Shejuti Brishty, Urmi Roy, Saikat Mitra, Md. Rafi, Md. Islam, Mst. Nesa, Md. Islam & Talha Emran. (2021) Clinical Efficacy and Safety of Antiviral Drugs in the Extended Use against COVID-19: What We Know So Far. Biologics 1:2, pages 252-284.
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Aarzoo Thakur, Shawn Pei Feng Tan & James Chun Yip Chan. (2020) Physiologically‐Based Pharmacokinetic Modeling to Predict the Clinical Efficacy of the Coadministration of Lopinavir and Ritonavir against SARS‐CoV‐2. Clinical Pharmacology & Therapeutics 108:6, pages 1176-1184.
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Roberta Prinapori, Raffaella Rosso, Antonio Di Biagio, Franca Miletich, Elisa Furfaro, Lucia Taramasso, Francesca Ginocchio, Vania Giacomet, Loredana Nulvesu, Maria Pia Sormani, Irene Schiavetti, Alessio Signori, Laura De Hoffer & Claudio Viscoli. (2013) Pharmacokinetics of Lopinavir Determined with an ELISA Test in Youths with Perinatally Acquired HIV. The Indian Journal of Pediatrics.
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Arunee Klinklom, Thanyawee Puthanakit, Meena Gorowara, Chayapa Phasomsap, Stephen Kerr, Chulalak Sriheara, Jintanat Ananworanich, David Burger, Kiat Ruxrungtham & Chitsanu Pancharoen. (2012) Low Dose Lopinavir/Ritonavir Tablet Achieves Adequate Pharmacokinetic Parameters in HIV-Infected Thai Adolescents. Antiviral Therapy 17:2, pages 283-289.
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Frantz Foissac, Saïk Urien, Déborah Hirt, Pierre Frange, Marie-Laure Chaix, Jean-Marc Treluyer & Stéphane Blanche. (2011) Pharmacokinetics and Virological Efficacy after Switch to Once-Daily Lopinavir-Ritonavir in Treatment-Experienced HIV-1-Infected Children. Antimicrobial Agents and Chemotherapy 55:9, pages 4320-4325.
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Jamie D. Croxtall & Caroline M. Perry. (2010) Lopinavir/Ritonavir. Drugs 70:14, pages 1885-1915.
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Natella Rakhmanina, John van den Anker, Aline Baghdassarian, Steven Soldin, Keetra Williams & Michael N. Neely. (2009) Population Pharmacokinetics of Lopinavir Predict Suboptimal Therapeutic Concentrations in Treatment-Experienced Human Immunodeficiency Virus-Infected Children. Antimicrobial Agents and Chemotherapy 53:6, pages 2532-2538.
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Joseph Gathe, Barbara A da Silva, Daniel E Cohen, Mona R Loutfy, Daniel Podzamczer, Rafael Rubio, Sara Gibbs, Theresa Marsh, Christian Naylor, Linda Fredrick & Barry Bernstein. (2009) A Once-Daily Lopinavir/Ritonavir-Based Regimen Is Noninferior to Twice-Daily Dosing and Results in Similar Safety and Tolerability in Antiretroviral-Naive Subjects Through 48 Weeks. JAIDS Journal of Acquired Immune Deficiency Syndromes 50:5, pages 474-481.
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Martine Caron, Corinne Vigouroux, Jean-Philippe Bastard & Jacqueline Capeau. (2009) Antiretroviral-Related Adipocyte Dysfunction and Lipodystrophy in HIV-Infected Patients: Alteration of the PPAR -Dependent Pathways . PPAR Research 2009, pages 1-8.
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Brian L. Robbins, Edmund V. Capparelli, Ellen G. Chadwick, Ram Yogev, Leslie Serchuck, Carol Worrell, Mary Elizabeth Smith, Carmelita Alvero, Terence Fenton, Barbara Heckman, Stephen I. Pelton, Grace Aldrovandi, William Borkowsky, John Rodman & Peter L. Havens. (2008) Pharmacokinetics of High-Dose Lopinavir-Ritonavir with and without Saquinavir or Nonnucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus-Infected Pediatric and Adolescent Patients Previously Treated with Protease Inhibitors. Antimicrobial Agents and Chemotherapy 52:9, pages 3276-3283.
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. (2008) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 17:4.
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Graham S Cooke. (2007) Evolution of adult antiretroviral therapy for programmatic delivery in Africa and the potential role for new therapeutic approaches. Therapy 4:6, pages 767-774.
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