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Nuclear Technology Volume 129, 2000 - Issue 2
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Technical Paper

Neutron Beam Optimization for Boron Neutron Capture Therapy Using the D-D and D-T High-Energy Neutron Sources

Jérôme M. VerbekeUniversity of California, BerkeleyNuclear Engineering Department, Berkeley, California 94720 and Ernest Orlando Lawrence Berkeley National Laboratory 1 Cyclotron Road, Berkeley, California 94720
,
Jasmina L. VujicUniversity of California, BerkeleyNuclear Engineering Department, Berkeley, California 94720
&
Ka-Ngo LeungErnest Orlando Lawrence Berkeley National Laboratory 1 Cyclotron Road, Berkeley, California 94720
Pages 257-278 | Published online: 12 May 2017

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Francesco Ganda, Jasmina Vujic, Ehud Greenspan & Ka-Ngo Leung. (2010) Compact D-D Neutron Source-Driven Subcritical Multiplier and Beam-Shaping Assembly for Boron Neutron Capture Therapy. Nuclear Technology 172:3, pages 302-324.
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Articles from other publishers (30)

Yi Ge, Jingang Liang, Qiong Zhang, Wei Tang & Agustin Munoz-Garcia. (2022) A comparison study of GEANT4 and MCNP6 on neutron-induced gamma simulation. Applied Radiation and Isotopes 190, pages 110514.
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A. Tedjani, R. Abdi, D. Boumala, A. Belafrites & J.-E. Groetz. (2022) Boron neutron capture therapy: Dosimetric evaluation of a brain tumor and surrounding healthy tissues using Monte Carlo Simulation. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 1040, pages 167240.
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Seth W. Streitmatter, Robert D. Stewart, Gregory Moffitt & Tatjana Jevremovic. (2020) Mechanistic Modeling of the Relative Biological Effectiveness of Boron Neutron Capture Therapy. Cells 9:10, pages 2302.
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M. Nanbedeh, S.M. Sadat-Kiai, A. Aghamohamadi & M. Hassanzadeh. (2020) A feasibility study of the Iranian Sun mather type plasma focus source for neutron capture therapy using MCNP X2.6, Geant4 and FLUKA codes. Nuclear Engineering and Technology 52:5, pages 1002-1007.
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Ka-Ngo Leung, James K. Leung & Graeme Melville. (2018) Feasibility study on medical isotope production using a compact neutron generator. Applied Radiation and Isotopes 137, pages 23-27.
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G S Sahoo, S D Sharma, S P Tripathy & T Bandyopadhyay. (2017) Design and dosimetric evaluation of beam shaping assembly for BNCT of compact D–T neutron generator by Monte Carlo simulation. Biomedical Physics & Engineering Express 4:1, pages 015018.
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Hamza Naeem, Chaobin Chen, Huaqing Zheng & Jing Song. (2017) Optimization of beam shaping assembly based on D-T neutron generator and dose evaluation for BNCT. Journal of the Korean Physical Society 70:8, pages 816-821.
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S. Farhad Masoudi, Fatemeh S. Rasouli & Marjan Ghasemi. (2017) BNCT of skin tumors using the high-energy D-T neutrons. Applied Radiation and Isotopes 122, pages 158-163.
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文强 李. (2017) One Design of the Neutron Generator for BNCT. Nuclear Science and Technology 05:04, pages 195-203.
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Shuang Hang, Xiaobin Tang, Diyun Shu, Yuanhao Liu, Changran Geng, Chunhui Gong, Haiyan Yu & Da Chen. (2016) Monte Carlo study of the beam shaping assembly optimization for providing high epithermal neutron flux for BNCT based on D–T neutron generator. Journal of Radioanalytical and Nuclear Chemistry 310:3, pages 1289-1298.
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S. Farhad Masoudi & Fatemeh S. Rasouli. (2015) Investigating a multi-purpose target for electron linac based photoneutron sources for BNCT of deep-seated tumors. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 356-357, pages 146-153.
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Yoshinori Sakurai, Hiroki Tanaka, Takushi Takata, Nozomi Fujimoto, Minoru Suzuki, Shinichiro Masunaga, Yuko Kinashi, Natsuko Kondo, Masaru Narabayashi, Yosuke Nakagawa, Tsubasa Watanabe, Koji Ono & Akira Maruhashi. (2015) Advances in boron neutron capture therapy (BNCT) at kyoto university - From reactor-based BNCT to accelerator-based BNCT. Journal of the Korean Physical Society 67:1, pages 76-81.
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R.H. Avagyan & I.A. Kerobyan. (2015) Conceptual design project: Accelerator complex for nuclear physics studies and boron neutron capture therapy application at the Yerevan Physics Institute (YerPhI) Yerevan, Armenia. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 355, pages 344-346.
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Fatemeh S. Rasouli & S. Farhad Masoudi. (2015) A study on the optimum fast neutron flux for Boron Neutron Capture Therapy of deep-seated tumors. Applied Radiation and Isotopes 96, pages 45-51.
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Mitsuru Uesaka & Hitoshi Kobayashi. (2016) Compact Neutron Sources for Energy and Security. Reviews of Accelerator Science and Technology 08, pages 181-207.
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D. Krstic, V. M. Markovic, Z. Jovanovic, B. Milenkovic, D. Nikezic & J. Atanackovic. (2014) Monte Carlo calculations of lung dose in ORNL phantom for boron neutron capture therapy. Radiation Protection Dosimetry 161:1-4, pages 269-273.
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Fatemeh Torabi, S. Farhad Masoudi, Faezeh Rahmani & Fatemeh S. Rasouli. (2014) BSA optimization and dosimetric assessment for an electron linac based BNCT of deep‐seated brain tumors. Journal of Radioanalytical and Nuclear Chemistry 300:3, pages 1167-1174.
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S. Farhad Masoudi & Masoud Ghashami. (2014) D–T neutron generators as a feasibility tool for landmine detection based on neutron backscattering method. Annals of Nuclear Energy 65, pages 441-445.
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Sauli Savolainen, Mika Kortesniemi, Marjut Timonen, Vappu Reijonen, Linda Kuusela, Jouni Uusi-Simola, Eero Salli, Hanna Koivunoro, Tiina Seppälä, Nadja Lönnroth, Petteri Välimäki, Heini Hyvönen, Petri Kotiluoto, Tom Serén, Antti Kuronen, Sami Heikkinen, Antti Kosunen & Iiro Auterinen. (2013) Boron neutron capture therapy (BNCT) in Finland: Technological and physical prospects after 20 years of experiences. Physica Medica 29:3, pages 233-248.
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Fatemeh S. Rasouli & S. Farhad Masoudi. (2012) Design and optimization of a beam shaping assembly for BNCT based on D–T neutron generator and dose evaluation using a simulated head phantom. Applied Radiation and Isotopes 70:12, pages 2755-2762.
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Fatemeh S. Rasouli, S. Farhad Masoudi & Yaser Kasesaz. (2012) Design of a model for BSA to meet free beam parameters for BNCT based on multiplier system for D–T neutron source. Annals of Nuclear Energy 39:1, pages 18-25.
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Ka-Ngo Leung. 2012. Neutron Capture Therapy. Neutron Capture Therapy 55 67 .
M.R. Eskandari & S. Kashian. (2009) Design of moderator and multiplier systems for D–T neutron source in BNCT. Annals of Nuclear Energy 36:8, pages 1100-1102.
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Ximan Jiang, Ye Chen, Lili Ji, Qing Ji & Ka-Ngo Leung. (2005) Development of a 27.12MHz radio frequency driven ion source with 3mTorr operation pressure for neutron generators. Review of Scientific Instruments 76:10, pages 103302.
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H Koivunoro, D.L Bleuel, U Nastasi, T.P Lou, J Reijonen & K-N Leung. (2004) BNCT dose distribution in liver with epithermal D–D and D–T fusion-based neutron beams. Applied Radiation and Isotopes 61:5, pages 853-859.
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J. Rassow, W. Sauerwein, A. Wittig, E. Bourhis-Martin, K. Hideghéty & R. Moss. (2004) Advantage and limitations of weighting factors and weighted dose quantities and their units in boron neutron capture therapy. Medical Physics 31:5, pages 1128-1134.
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Guido Martı́n & Arian Abrahantes. (2004) A conceptual design of a beam-shaping assembly for boron neutron capture therapy based on deuterium-tritium neutron generators. Medical Physics 31:5, pages 1116-1122.
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Guillermo F. Quinteiro. (2004) Beam optimization: improving methodology. Annals of Nuclear Energy 31:4, pages 399-411.
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M Angelone, S Atzeni & S Rollet. (2002) Conceptual study of a compact accelerator-driven neutron source for radioisotope production, boron neutron capture therapy and fast neutron therapy. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 487:3, pages 585-594.
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D. L. Bleuel, R. J. Donahue, B. A. Ludewigt & J. Vujic. 2001. Advanced Monte Carlo for Radiation Physics, Particle Transport Simulation and Applications. Advanced Monte Carlo for Radiation Physics, Particle Transport Simulation and Applications 833 840 .

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