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Article

Pro Islet Amyloid Polypeptide (ProIAPP) Immunoreactivity in the Islets of Langerhans

, M.D., , , &
Pages 97-106 | Published online: 02 Mar 2011

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Per Westermark. (2011) Amyloid in the islets of Langerhans: Thoughts and some historical aspects. Upsala Journal of Medical Sciences 116:2, pages 81-89.
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Gunilla T Westermark, Per Westermark, Astrid Nordin, Eva Törnelius & Arne Andersson. (2003) Formation of amyloid in human pancreatic islets transplanted to the liver and spleen of nude mice. Upsala Journal of Medical Sciences 108:3, pages 193-204.
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Ana F. Raimundo, Sofia Ferreira, Francisco A. Tomás-Barberán, Claudia N. Santos & Regina Menezes. (2021) Urolithins: Diet-Derived Bioavailable Metabolites to Tackle Diabetes. Nutrients 13:12, pages 4285.
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Steven E Kahn, Yi-Chun Chen, Nathalie Esser, Austin J Taylor, Daniël H van Raalte, Sakeneh Zraika & C Bruce Verchere. (2021) The β Cell in Diabetes: Integrating Biomarkers With Functional Measures. Endocrine Reviews 42:5, pages 528-583.
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Mark Germanos, Andy Gao, Matthew Taper, Belinda Yau & Melkam A. Kebede. (2021) Inside the Insulin Secretory Granule. Metabolites 11:8, pages 515.
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Ana F. Raimundo, Sofia Ferreira, Ivo C. Martins & Regina Menezes. (2020) Islet Amyloid Polypeptide: A Partner in Crime With Aβ in the Pathology of Alzheimer's Disease. Frontiers in Molecular Neuroscience 13.
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Michael C. Owen, David Gnutt, Mimi Gao, Sebastian K. T. S. Wärmländer, Jüri Jarvet, Astrid Gräslund, Roland Winter, Simon Ebbinghaus & Birgit Strodel. (2019) Effects of in vivo conditions on amyloid aggregation . Chemical Society Reviews 48:14, pages 3946-3996.
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Jaques A. Courtade, Agnieszka M. Klimek-Abercrombie, Yi-Chun Chen, Nirja Patel, Phoebe Y. T. Lu, Cate Speake, Paul C. Orban, Behzad Najafian, Graydon Meneilly, Carla J. Greenbaum, Garth L. Warnock, Constadina Panagiotopoulos & C. Bruce Verchere. (2017) Measurement of Pro-Islet Amyloid Polypeptide (1–48) in Diabetes and Islet Transplants. The Journal of Clinical Endocrinology & Metabolism 102:7, pages 2595-2603.
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Thomas A. Lutz & Urs Meyer. (2015) Amylin at the interface between metabolic and neurodegenerative disorders. Frontiers in Neuroscience 9.
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Sanda Despa, Savita Sharma, Todd R. Harris, Hua Dong, Ning Li, Nipavan Chiamvimonvat, Heinrich Taegtmeyer, Kenneth B. Margulies, Bruce D. Hammock & Florin Despa. (2014) Cardioprotection by Controlling Hyperamylinemia in a “Humanized” Diabetic Rat Model. Journal of the American Heart Association 3:4.
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Hui Wang & Daniel P. Raleigh. (2014) The Ability of Insulin To Inhibit the Formation of Amyloid by Pro-Islet Amyloid Polypeptide Processing Intermediates Is Significantly Reduced in the Presence of Sulfated Glycosaminoglycans. Biochemistry 53:16, pages 2605-2614.
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Juan R. Peinado, Furqan Sami, Nina Rajpurohit & Iris Lindberg. (2013) Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS. FEBS Letters 587:21, pages 3406-3411.
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Per Westermark, Arne Andersson & Gunilla T. Westermark. (2011) Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus. Physiological Reviews 91:3, pages 795-826.
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Sebastian Wolfgang Schultz, K. Peter R. Nilsson & Gunilla Torstensdotter Westermark. (2011) Drosophila Melanogaster as a Model System for Studies of Islet Amyloid Polypeptide Aggregation. PLoS ONE 6:6, pages e20221.
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Katrin Weise, Rajesh Mishra, Suman Jha, Daniel Sellin, Diana Radovan, Andrea Gohlke, Christoph Jeworrek, Janine Seeliger, Simone Möbitz & Roland Winter. 2011. Lipids and Cellular Membranes in Amyloid Diseases. Lipids and Cellular Membranes in Amyloid Diseases 93 120 .
Fanling Meng & Daniel P. Raleigh. (2011) Inhibition of Glycosaminoglycan-Mediated Amyloid Formation by Islet Amyloid Polypeptide and proIAPP Processing Intermediates. Journal of Molecular Biology 406:3, pages 491-502.
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Gunilla T. Westermark. 2011. BetaSys. BetaSys 363 386 .
Vita Chien, Jacqueline F. Aitken, Shaoping Zhang, Christina M. Buchanan, Anthony Hickey, Thomas Brittain, Garth J. S. CooperKerry M. Loomes. (2010) The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes. Biochemical Journal 432:1, pages 113-121.
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Andisheh Abedini & Daniel P. Raleigh. 2010. Protein Misfolding Diseases. Protein Misfolding Diseases 517 541 .
Suman Jha, Daniel Sellin, Ralf Seidel & Roland Winter. (2009) Amyloidogenic Propensities and Conformational Properties of ProIAPP and IAPP in the Presence of Lipid Bilayer Membranes. Journal of Molecular Biology 389:5, pages 907-920.
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. (2008) Amyloid and Transplanted Islets. New England Journal of Medicine 359:25, pages 2729-2731.
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Melanie R. Nilsson. 2008. Protein Science Encyclopedia. Protein Science Encyclopedia 81 109 .
Arne Andersson, Sara Bohman, L. A. H?kan Borg, Johan F. Paulsson, Sebastian W. Schultz, Gunilla T. Westermark & Per Westermark. (2008) Amyloid Deposition in Transplanted Human Pancreatic Islets: A Conceivable Cause of Their Long-Term Failure. Experimental Diabetes Research 2008, pages 1-8.
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Fanling Meng, Andisheh Abedini, Benben Song & Daniel P. Raleigh. (2007) Amyloid Formation by Pro-Islet Amyloid Polypeptide Processing Intermediates:  Examination of the Role of Protein Heparan Sulfate Interactions and Implications for Islet Amyloid Formation in Type 2 Diabetes. Biochemistry 46:43, pages 12091-12099.
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Anne Clark & Jenni Moffitt. 2007. Protein Misfolding, Aggregation, and Conformational Diseases. Protein Misfolding, Aggregation, and Conformational Diseases 199 216 .
Andisheh Abedini, Sylvia M. Tracz, Jae-Hyun Cho & Daniel P. Raleigh. (2006) Characterization of the Heparin Binding Site in the N-Terminus of Human Pro-Islet Amyloid Polypeptide:  Implications for Amyloid Formation. Biochemistry 45:30, pages 9228-9237.
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Jo W.M. Höppener & Cees J.M. Lips. (2006) Role of islet amyloid in type 2 diabetes mellitus. The International Journal of Biochemistry & Cell Biology 38:5-6, pages 726-736.
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Melanie R. Nilsson. 2005. Amyloid Proteins. Amyloid Proteins 81 109 .
Gunilla T. Westermark. 2005. Amyloid Proteins. Amyloid Proteins 723 754 .
Per Westermark, Arne Andersson & Gunilla T. Westermark. (2005) Is aggregated IAPP a cause of beta-cell failure in transplanted human pancreatic islets?. Current Diabetes Reports 5:3, pages 184-188.
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Sofianos Andrikopoulos, Rebecca L. Hull, C. Bruce Verchere, Feng Wang, Shani M. Wilbur, Thomas N. Wight, Lucy Marzban & Steven E. Kahn. (2004) Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide. American Journal of Physiology-Endocrinology and Metabolism 286:3, pages E418-E424.
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Makiko Umezawa, Kenjiro Tatematsu, Tatsumi Korenaga, Xiaoying Fu, Takatoshi Matushita, Harumi Okuyama, Masanori Hosokawa, Toshio Takeda & Keiichi Higuchi. (2003) Dietary fat modulation of apoA-II metabolism and prevention of senile amyloidosis in the senescence- accelerated mouse. Journal of Lipid Research 44:4, pages 762-769.
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J. S. Wall, M. Schell, R. Hrncic, F. J. Stevens & A. Solomon. 2003. Monoclonal Gammopathies and the Kidney. Monoclonal Gammopathies and the Kidney 203 214 .

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