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Expert Opinion on Therapeutic Patents Volume 19, 2009 - Issue 5
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Patent Evaluations

MDM2/MDMX inhibitor peptide: WO2008106507

Antonio Macchiarulo Dipartimento di Chimica e Tecnologia del Farmaco, Via del Liceo 1, 06123 Perugia (Italy) +39 075 585 5120; +39 075 585 5114; [email protected]
&
Roberto Pellicciari Dipartimento di Chimica e Tecnologia del Farmaco, Via del Liceo 1, 06123 Perugia (Italy) +39 075 585 5120; +39 075 585 5114; [email protected]
Pages 721-726 | Published online: 09 May 2009

Citations (9)

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Antonio Macchiarulo, Nicola Giacchè, Francesca Mancini, Efisio Puxeddu, Fabiola Moretti & Roberto Pellicciari. (2011) Alternative strategies for targeting mouse double minute 2 activity with small molecules: novel patents on the horizon?. Expert Opinion on Therapeutic Patents 21:3, pages 287-294.
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Articles from other publishers (8)

Nidhi Singh & Wenjin Li. (2020) Absolute Binding Free Energy Calculations for Highly Flexible Protein MDM2 and Its Inhibitors. International Journal of Molecular Sciences 21:13, pages 4765.
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Avipsha Sarkar & Shampa Sen. (2019) A Comparative Analysis of the Molecular Interaction Techniques for In Silico Drug Design. International Journal of Peptide Research and Therapeutics 26:1, pages 209-223.
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Mariateresa Giustiniano, Simona Daniele, Sveva Pelliccia, Valeria La Pietra, Deborah Pietrobono, Diego Brancaccio, Sandro Cosconati, Anna Messere, Stefano Giuntini, Linda Cerofolini, Marco Fragai, Claudio Luchinat, Sabrina Taliani, Giuseppe La Regina, Federico Da Settimo, Romano Silvestri, Claudia Martini, Ettore Novellino & Luciana Marinelli. (2017) Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure–Activity Relationship Studies and Pharmacological Activity. Journal of Medicinal Chemistry 60:19, pages 8115-8130.
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Sahand Golestanian, Amirhossein Sharifi, Grzegorz M. Popowicz, Homa Azizian, Alireza Foroumadi, Aleksandra Szwagierczak, Tad A. Holak & Massoud Amanlou. (2016) Discovery of novel dual inhibitors against Mdm2 and Mdmx proteins by in silico approaches and binding assay. Life Sciences 145, pages 240-246.
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Nader Touqan, Christine P Diggle, Edlo T Verghese, Sarah Perry, Kieran Horgan, William Merchant, Rashida Anwar, Alexander F Markham, Ian M Carr & Rajgopal Achuthan. (2013) An observational study on the expression levels of MDM2 and MDMX proteins, and associated effects on P53 in a series of human liposarcomas. BMC Clinical Pathology 13:1.
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Antonio Macchiarulo, Nicola Giacchè, Andrea Carotti, Fabiola Moretti & Roberto Pellicciari. (2011) Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4). MedChemComm 2:6, pages 455.
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Cristina Dezi, Andrea Carotti, Matteo Magnani, Massimo Baroni, Alessandro Padova, Gabriele Cruciani, Antonio Macchiarulo & Roberto Pellicciari. (2010) Molecular Interaction Fields and 3D-QSAR Studies of p53−MDM2 Inhibitors Suggest Additional Features of Ligand−Target Interaction. Journal of Chemical Information and Modeling 50:8, pages 1451-1465.
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Ryo Hayashi, Deyun Wang, Toshiaki Hara, Jaclyn A. Iera, Stewart R. Durell & Daniel H. Appella. (2009) N-Acylpolyamine inhibitors of HDM2 and HDMX binding to p53. Bioorganic & Medicinal Chemistry 17:23, pages 7884-7893.
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