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Expert Opinion on Therapeutic Patents Volume 19, 2009 - Issue 11
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Patent Evaluations

AZD-4818, a chemokine CCR1 antagonist: WO2008103126 and WO2009011653

Peter Norman Norman Consulting, 18 Pink lane, Burnham, Bucks, SL1 8JW, UK [email protected]
Pages 1629-1633 | Published online: 08 Jul 2009

Citations (10)

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Read on this site (2)

Sonia Vallet & Kenneth C Anderson. (2011) CCR1 as a target for multiple myeloma. Expert Opinion on Therapeutic Targets 15:9, pages 1037-1047.
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Percy H Carter & John Hynes. (2010) N-aryl pyrazoles, indazoles and azaindazoles as antagonists of CC chemokine receptor 1: patent cooperation treaty applications WO2010/036632, WO2009/134666 and WO2009/137338. Expert Opinion on Therapeutic Patents 20:11, pages 1609-1618.
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Articles from other publishers (8)

Joseph B. SantellaIIIIII, Daniel S. Gardner, John V. Duncia, Hong Wu, Murali Dhar, Cullen Cavallaro, Andrew J. Tebben, Percy H. Carter, Joel C. Barrish, Melissa Yarde, Stephanie W. Briceno, Mary Ellen Cvijic, R. Robert Grafstrom, Richard Liu, Sima R. Patel, Andrew J. Watson, Guchen Yang, Anne V. Rose, Rodney D. Vickery, Janet Caceres-Cortes, Christian Caporuscio, Daniel M. Camac, Javed A. Khan, Yongmi An, William R. Foster, Paul Davies & John HynesJr.Jr.. (2014) Discovery of the CCR1 Antagonist, BMS-817399, for the Treatment of Rheumatoid Arthritis. Journal of Medicinal Chemistry 57:18, pages 7550-7564.
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Daniel S. Gardner, Joseph B. SantellaIIIIII, John V. Duncia, Percy H. Carter, T.G.Murali Dhar, Hong Wu, Weiwei Guo, Cullen Cavallaro, Katy Van Kirk, Melissa Yarde, Stephanie W. Briceno, R. Robert Grafstrom, Richard Liu, Sima R. Patel, Andrew J. Tebben, Dan Camac, Javed Khan, Andrew Watson, Guchen Yang, Anne Rose, William R. Foster, Mary Ellen Cvijic, Paul Davies & John HynesJr.Jr.. (2013) The discovery of BMS-457, a potent and selective CCR1 antagonist. Bioorganic & Medicinal Chemistry Letters 23:13, pages 3833-3840.
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Maikel Wijtmans, Danny J. Scholten, Iwan J.P. de Esch, Martine J. Smit & Rob Leurs. (2012) Therapeutic targeting of chemokine receptors by small molecules. Drug Discovery Today: Technologies 9:4, pages e229-e236.
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Cullen L. Cavallaro, Stephanie Briceno, Jing Chen, Mary Ellen Cvijic, Paul Davies, John HynesJr.Jr., Rui-Qin Liu, Sandhya Mandlekar, Anne V. Rose, Andrew J. Tebben, Katy Van Kirk, Andrew Watson, Hong Wu, Guchen Yang & Percy H. Carter. (2012) Discovery and Lead Optimization of a Novel Series of CC Chemokine Receptor 1 (CCR1)-Selective Piperidine Antagonists via Parallel Synthesis. Journal of Medicinal Chemistry 55:22, pages 9643-9653.
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J. ROBERT MERRITT & ANNETTE GILCHRIST. 2012. Anti-Inflammatory Drug Discovery. Anti-Inflammatory Drug Discovery 329 349 .
Angela R Karash & Annette Gilchrist. (2011) Therapeutic potential of CCR1 antagonists for multiple myeloma. Future Medicinal Chemistry 3:15, pages 1889-1908.
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Carl G Persson & Lena Uller. (2010) Resolution of cell-mediated airways diseases. Respiratory Research 11:1.
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J. Robert Merritt, Ray James, Vidyadhar M. Paradkar, Chongwu Zhang, Ruiyan Liu, Jinqi Liu, Biji Jacob, Camelia Chiriac, Michael J. Ohlmeyer, Elizabeth Quadros, Pamela Wines, Jennifer Postelnek, Catherine M. Hicks, Weiqing Chen, Earl F. Kimble, Linda O’Brien, Nicole White, Hema Desai, Kenneth C. Appell & Maria L. Webb. (2010) Novel pyrrolidine heterocycles as CCR1 antagonists. Bioorganic & Medicinal Chemistry Letters 20:18, pages 5477-5479.
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